In vitro Release of Eosinophil Proteins in Allergic and Atopic Dermatitis Patients by L. K. Poulsen, C. M. Reimert, C. Bindslev-Jensen

“…To investigate whether eosinophils are stimulated in vivo or have acquired an increased susceptibility to stimuli from the coagulation cascade, the release of eosinophil proteins was compared for three groups of donors with different levels of serum IgE. (1) with atopic dermatitis (s-IgE > 5000 IU/ml, n = 11); (2) with inhalant allergy (200 < s-IgE < 2 000 IU/ml, n = 10); and (3) non-allergic (s- IgE < 100 IU/ml, n = 10). …”
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Ethanol Extract of Sesamum indicum Linn. Inhibits FcεRI-Mediated Allergic Reaction via Regulation of Lyn/Syk and Fyn Signaling Pathways in Rat Basophilic Leukemic RBL-2H3 Mast Cell... by Hyun Ju Do, Tae Woo Oh, Kwang-Il Park

“…SIE inhibited the degranulation and secretion of inflammatory mediators in antigen/IgE-sensitized mast cells. SIE reduced the expressions of FcεRI signaling-related genes, such as Syk, Lyn, and Fyn, and the phosphorylation of extracellular signal-regulated kinase in antigen/IgE-sensitized mast cells. …”
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Allergen sensitization patterns: Allergic rhinitis with multimorbidity versus alone—A real‐world study by Ya‐Ting Li, Qi‐Qing Ye, Ya‐Xin Lu, Ke‐Xin Yang, Ping‐Ping Zhang, Chang Chen, Min Zhou, Pei‐Ying Feng, Zhuang‐Gui Chen

“…Allergic multimorbidity often involves polysensitization, where allergen‐specific immunoglobulin E (IgE) plays a significant role. Objective This study aims to explore differences in allergen IgE sensitization patterns between AR alone and AR multimorbidity. …”
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Efficacy and safety of sublingual immunotherapy using a combination of Dermatophagoides pteronyssinus and Blomia tropicalis extracts in patients with allergic rhinitis: A randomize... by Priscilla Rios Cordeiro Macedo, MD, MSc, Priscila Moraes, MD, Luísa Karla Arruda, MD, PhD, Fábio Fernandes Morato Castro, MD, PhD, Jorge Kalil, MD, PhD, Clóvis Eduardo Santos Galvão, MD, PhD

“…Total serum IgE, serum specific IgE, and IgG4 levels for Der p 1 and Blo t were assessed at baseline and, 6 and 12 months after treatment. …”
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Clinical Response Predictive Model for Omalizumab in Moderate-to-Severe Asthma Patients by Ruiqi Qian, Lingyi Yang, Xurui Shen, Cheng Chen, Jianan Huang, Xiuqin Zhang, Cuiping Fu

“…The serum level of total IgE increased significantly after injection of omalizumab, while blood eosinophils count decreased significantly from baseline. …”
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Th2 cells and cytokine networks in allergic inflammation of the lung by Anthony J. Coyle, Shogo Tsuyuki

“…The cytokines released from Th2 and Th2-like cells are likely to be central to the pathophysiolgy of asthma and allergy, contributing to aberrant IgE production, eosinophilia and, perhaps, mucosal susceptibility to viral infection. …”
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Cow milk αs1-casein induces allergic responses in a mouse model of atopy by Guangyu Wang, Xiaofeng Yu, Yanjun Cong, Linfeng Li

“…The levels of specific IgE, mast cell proteinase, histamine and cytokines in sensitized mice were determined, and the clinical and pathological observation were evaluated. …”
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The inhibitory effect of anti-allergic agent suplatast tosilate (IPD–1151T) on methacholine- and allergen-induced bronchoconstriction in sensitized mice by Kazuhito Asano, Tetsuya Mizutani, Toshikazu Shimane, Masataka Hisano, Tadashi Hisamitsu, Harumi Suzaki

“…We also examined the effect of IPD-1151T on IgE production in response to DNP-KLH immunization. …”
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Investigation of gut microbiota in pediatric patients with peanut allergy in outpatient settings by Shouming Li, Jingyi Huang, Yunyun Xie, Di Wang, Xin Tan, Yufan Wang

“…The PA group was defined by a positive reaction to peanut-specific IgE tests, while the Ctl group tested negative for peanut IgE and had no history of allergies. …”
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Association of LPCAT1-rs8352 genetic variant with susceptibility and severity of pediatric bronchial asthma: a case-control study by Khalid M. Mohany, Yasser Gamal, Yaser F. Abdel Raheem

“…ECP, hs-CRP, and total IgE serum levels were measured using their corresponding ELISA kits. …”
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A Case of Fish Sausage Anaphylaxis Induced by Epicutaneous Sensitization to Carmine Contained in Eyeshadows: The Effect of Chelation on Carmine Allergy by Maiko Yamaura, Yuriko Iwahashi, Eri Hashimoto, Jun Miura, Yuri Murayama, Sachiko Koshikawa, Naoko Inomata

“…SPT was also positive for carmine. In IgE-immunoblotting using the eyeshadow and fish sausage, the patient serum IgE was bound to three protein bands at approximately 86, 114, and 130 kDa. …”
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Gender-Related Effects of Sex Steroids on Histamine Release and FcεRI Expression in Rat Peritoneal Mast Cells by Samira Muñoz-Cruz, Yolanda Mendoza-Rodríguez, Karen E. Nava-Castro, Lilián Yepez-Mulia, Jorge Morales-Montor

“…In addition to the well-characterized IgE/FcεRI-mediated degranulation, a variety of biological substances can induce MCs activation and release of their granule content. …”
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Atypical Presentation of Kimura’s Disease in a Male Patient: A Case Report and Review of Literature by Zahra A. Natsha, Islam A. Hamarsheh, Rawan S. Utt, Bassam Abu Alrob, Adnan A. Wahdan

“…It primarily affects the head and neck region, presenting as deep subcutaneous masses, and is often accompanied by triad regional lymphadenopathy, salivary gland involvement, and high serum immunoglobulin E (IgE) levels. Here, we report the second documented case of KD in Palestine diagnosed in a 28-year-old male patient who presented with lymphadenopathy and increased serum immunoglobulin E and G (IgE and IgG) associated with intermittent abdominal pain, generalised fatigue, hepatomegaly, cardiomyopathy, reactive airway disease, peripheral vasculopathy, peripheral neuropathy, and focal segmental glomerulosclerosis. …”
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Asthma in Children and Adults: A Shared Biological and Molecular Basis by Paolo M Renzi

“…Eosinophilia and increased immunoglobulin (Ig) E levels are present at every age except in young infants. …”
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Kimura disease: A rare presentation in the rheumatology clinic by Malay Kumar, Arun Hegde, Gunjan Dwivedi, Prashant Sengupta, Kovilapu Uday Bhanu

“…Blood and tissue eosinophilia, and elevated immunoglobulin E (IgE) levels, are common associations. Characteristic histopathological findings of biopsy specimens obtained from the subcutaneous swellings or lymph nodes include eosinophilic infiltrates, follicular hyperplasia, and proliferation of postcapillary venules. …”
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Trichoscopy in Unveiling the Triad of Netherton Syndrome by H Bangaru, D Ashwini

“…Trichoscopy showed trichorrhexis nodosa, “golf-tee” hair, “bamboo” hair, and “matchstick” hair over eyebrows. Serum IgE levels were raised. Skin biopsy was suggestive of ILC. …”
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Changes in Serum Immunoglobulin Levels Play as Predictors of Treatment Response and Prognosis in Pediatric Idiopathic Nephrotic Syndrome During the Remission Phase by Amin sadat Sharif, Naghmeh Nickravesh, Marzieh Heidarzadeh Arani, Mohammad Javad Azadchehr, Hossein Motedayyen

“…Blood samples were collected from participants and serum values of IgG, IgM, IgE, and IgA were measured using EISA KITS from Aptech Services. …”
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Phadiatop Infant in the Diagnosis of Atopy in Children with Allergy-Like Symptoms by Ragnhild Halvorsen, Åsa Jenner, Else Marie Hagelin, Magnus P. Borres

“…The doctor's diagnosis atopic/nonatopic was based on routinely used procedures such as clinical evaluation, SPT, total and allergen-specific IgE antibodies. The performance of Phadiatop Infant was evaluated in a blinded manner against this diagnosis. …”
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Coexistence of T-Cell Lymphoblastic Lymphoma and Ichthyosis Vulgaris: A Case Report by Şule Çalışkan Kamış, Begül Yağcı

“…The diagnosis of HIES was confirmed through clinical evaluation, including elevated serum IgE levels and associated symptoms. Skin findings, growth retardation, and HIES overlap with Online Mendelian Inheritance in Man (OMIM) #615508, and parental carrier status was confirmed. …”
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Management of Recurrent Lung Infections in a Case of Hyperimmunoglobulinemia E (or Job’s) Syndrome by M Arsenault, V Echave, C Fish, J-P Praud

“…The diagnosis of hyperimmunoglobulinemia E (hyper IgE) or Job’s syndrome was made in a five-month-old girl with chronic staphylococcal mastitis, elevated serum IgE and abnormal neutrophil chemotaxis. …”
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