Clinical Characterization of Patients with Chronic Spontaneous Urticaria according to Anti-TPO IgE Levels by Jorge Sánchez, Andres Sánchez, Ricardo Cardona

“…Chronic spontaneous urticaria (CSU) is a heterogeneous disease with some frequent comorbidities like autoimmune diseases, drug reactions, and inducible urticaria. IgE antibodies against thyroid peroxidase (anti-TPO IgE) could be associated with some of these clinical characteristics. …”
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Hyper-IgE Syndrome with STAT3 Mutation: A Case Report in Mainland China by Lixin Xie, Xiaoxiang Hu, Yang Li, Weihua Zhang, Liang'an Chen

“…In this paper, we firstly report a young man diagnosed of Hyper-IgE syndrome with STAT3 mutation in Mainland China, and investigate the autosomal dominant trait of his family members.…”
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CC-Chemokine CCL15 Expression and Possible Implications for the Pathogenesis of IgE-Related Severe Asthma by Yasuo Shimizu, Kunio Dobashi

“…We review the role of CCL15 in the pathogenesis of asthma and also discuss the influence of IgE-mediated immunomodulation via CCL15 and its receptor CCR1.…”
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Unveiling the Effect of Age and IgE Level on Alopecia Areata: Insights from Comparative RNAseq Analysis by Liu H, Yang S, Xian H, Liu Y, Zhang Y, Chen Y, Xu Y, Liu J, Yang B, Luo Y

“…Moreover, pediatric AA patients with atopic predisposition often exhibit elevated IgE levels, early onset, and a poor prognosis.Purpose: This study aimed to investigate the impact of age and IgE levels on AA by conducting RNA sequencing on scalp samples from AA patients with atopic predisposition, age-matched healthy controls, and AA samples with varying IgE levels.Patients and Methods: We employed the single-sample Gene Set Enrichment Analysis (ssGSEA) algorithm in conjunction with gene expression analysis to assess immune infiltration. …”
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哮喘患儿IL-12 、IL-13 与总IgE 水平变化 by 麦贤弟, 赵　莉, 檀卫平, 朱昌国, 黄花荣, 黄绍良

“…【目的】探讨哮喘患儿白细胞介素12(IL-12)、白细胞介素13(IL-13)与总免疫球蛋白E(总IgE)的变化。【方法】 取静脉血, 用ELISA 方法检测IL-12、IL-13 与总IgE 水平, 并对检测结果进行统计学处理。…”
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Improving predictability of IgE-high type 2 chronic sinusitis with nasal polyps in the biologic era by Austin Heffernan, Jobanjit Phulka, Andrew Thamboo

“…Patients meeting these parameters have a high pretest probability for elevated IgE and would benefit from IgE serology to determine qualification for omalizumab. …”
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Comparison of Blood and Tissue Eosinophil Count and Blood IgE in Patients with Chronic Sinusitis and Nasal Polyps by Masoud Asghari, Shadi Izadpanahi, Mina Heidari Esfahani

“…The purpose of this study was to compare blood and tissue eosinophils and serum IgE levels in patients with chronic sinusitis with nasal polyp in Vali-e-Asr hospital in 1397. …”
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Ethanol Extract of Ampelopsis brevipedunculata Rhizomes Suppresses IgE-Mediated Mast Cell Activation and Anaphylaxis by Ji-Yeong Park, Min-Jong Kim, Young-Ae Choi, Seung Woong Lee, Soyoung Lee, Yong Hyun Jang, Sang-Hyun Kim

“…For in vivo studies, we used ovalbumin-induced active systemic anaphylaxis (ASA) and immunoglobulin (Ig) E-mediated passive cutaneous anaphylaxis (PCA) models. …”
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IL-1β and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype by Yongkang Wu, Bei Cai, Junlong Zhang, Beilei Shen, Zhuochun Huang, Chunyu Tan, Carla C. Baan, Lanlan Wang

“…IL-6 correlated with both IgE and IL-1β levels in RF+IgE+ SLE patients (r2=0.583, P=0.027; r2=0.847, P=0.001), and IgE also correlated with IL-1β (r2=0.567, P=0.031). …”
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Immune responses in children with secondary infection of mycoplasma pneumoniae after COVID-19: focus on eosinophils and IgE by Pingping Wang, Jin Yao, Yaqiong Li, Zhanjun Zhang, Ruiling Zhang, Shouting Lu, Meixia Sun, Xiaorong Huang

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Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity by Sameer Bahal, Maha E. Houssen, Ania Manson, Lorena Lorenzo, Mark A. Russell, Noel G. Morgan, Fariba Tahami, Sofia Grigoriadou

“…We present the case of a 19-year-old female with a mild form of Autosomal Dominant Hyper IgE syndrome (HIES) associated with a loss-of-function mutation in STAT3. …”
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Murine model of cross-IgE sensitization and cross-anaphylactic reactions among multiple group food allergens by Ibrahim Musa, Fariba Ardalani, Nan Yang, Soheila J. Maleki, Xiu-Min Li, Xiu-Min Li, Xiu-Min Li

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A Novel STAT3 Gene Mutation Related Hyper-IgE Syndrome Misdiagnosed as Hidradenitis Suppurativa by Pragya Shrestha, Geetika Sabharwal, Gisoo Ghaffari

“…Although Hyper-IgE Syndrome (HIES) is a rare immunodeficiency disorder, presenting symptoms may be as common as lung and skin infections. …”
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Second-hand Smoke Increases Nitric Oxide and Alters the IgE Response in a Murine Model of Allergic Aspergillosis by Brian W. P. Seymour, Janice L. Peake, Kent E. Pinkerton, Viswanath P. Kurup, Laurel J. Gershwin

“…All Af sensitized mice in ambient air (Af + AIR) made elevated levels of IgE, IgG1, IgM, IgG2a and IgA. Af sensitized mice housed in ETS (Af + ETS) made similar levels of immunoglobulins except for IgE that was significantly reduced in the serum and bronchoalveolar lavage (BAL). …”
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Critical pathomechanisms of NSAID-exacerbated respiratory disease (N-ERD) clarified by treatment with omalizumab, an anti-IgE antibody by Hiroaki Hayashi, Makoto Ishii, Yoshinori Hasegawa, Masami Taniguchi

“…Our findings regarding omalizumab-associated mast cell inhibitory effects are indirect evidence that mast cell dysregulation and, possibly, IgE are pivotal components of N-ERD.…”
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A Case of Severe Asthma with Eosinophilic Otitis Media Successfully Treated with Anti-IgE Monoclonal Antibody Omalizumab by Azusa Okude, Etsuko Tagaya, Mitsuko Kondo, Manabu Nonaka, Jun Tamaoki

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Very Elevated IgE, Atopy, and Severe Infection: A Genomics-Based Diagnostic Approach to a Spectrum of Diseases by A. Chin, S. Balasubramanyam, C. M. Davis

“…Elevated IgE has been long recognized as an important clinical marker of atopy but can be seen in a myriad of conditions. …”
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The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses. by Colin M Fitzsimmons, Frances M Jones, Alex Stearn, Iain W Chalmers, Karl F Hoffmann, Jakub Wawrzyniak, Shona Wilson, Narcis B Kabatereine, David W Dunne

“…<h4>Background</h4>A human IgE response to Sm22.6 (a dominant IgE target in Schistosoma mansoni) is associated with the development of partial immunity. …”
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过敏性休克死亡豚鼠脏器中IgE、IL-4的表达及其法医学意义 by 肖凤, 王伴青, 唐和生, 孙朝越, 李梦军, 廖义林, 刘继志

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变应性鼻炎吸入性变应原特异性IgE检测分析

“…【目的】 为了了解广州地区变应性鼻炎主要吸入性变应原65377; 【方法】 采用德国敏筛(Allergyscreen)变应原检测系统,检测我院变应性鼻炎患者常见吸入性特异性IgE和总IgE含量,并将患者分成未成年组(≤18 岁)和成年组( > 18岁),回顾性分析我院不同年龄变应性鼻炎患者常见吸入性变应原特异性IgE阳性率及其分布差异65377; 【结果】 625例变应性鼻炎患者中吸入性变应原特异性IgE阳性率依次为尘螨84.32%65380;蟑螂19.04%65380;柏树15.20%65380;动物毛皮屑组合13.12%65380;树木花粉组合7.20%65380;矮豚草5.12%,葎草1.76%65380;蒿草1.76%65380;霉菌组合1.44%;总IgE阳性者413例(66.1%)明显低于特异性IgE阳性率;两组中最常见的变应原相似;未成年组屋尘螨的阳性率及敏感程度明显高于成年组(P < 0.01)65377; 【结论】 ①我院变应性鼻炎患者最主要的吸入性变应原是屋尘螨65380;蟑螂65380;柏树65380;动物毛皮屑,可为广州地区参考;②未成年人对尘螨过敏的比例及敏感程度均高于成年人65377;…”
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