Dietary Supplementation with Omega-3-PUFA-Rich Fish Oil Reduces Signs of Food Allergy in Ovalbumin-Sensitized Mice by Olívia Gonçalves de Matos, Sylvia Stella Amaral, Pedro Elias Marques Pereira da Silva, Denise Alves Perez, Débora Moreira Alvarenga, Adaliene Versiani Matos Ferreira, Jacqueline Alvarez-Leite, Gustavo Batista Menezes, Denise Carmona Cara

“…Allergic group mice had increased serum levels of antiovalbumin IgE and IgG1 and changes in small intestine, characterized by an increased edema, number of rolling leukocytes in microcirculation, eosinophil infiltration, mucus production, and Paneth cell degranulation, in comparison to non-allergic group. …”
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Identification and analysis of immunological activity of two isoforms of tropomyosin in Alectryonella plicatula by Shiqiang Yang, Yexin Chen, Fei Huan, Xinrong He, Xiao Yun, Hong Liu, Guixia Chen, Guangming Liu

“…Sequences and epitopes alignment with shellfish TMs revealed that amino acids of TM-β were more frequently recognized as IgE epitopes in other shellfish TMs than TM-α. Differences in structure and sequence account for the higher immunological activity of TM-β compared to TM-α. …”
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A méh- vagy darázscsípés okozta anafilaxiás sokk vizsgálata a triptáz enzim és a méh-, illetve darázsméreg specifikus immunglobulin E szintek vérből történő meghatározása alapján,... by Judit Kruzslitz, Gyula Ludányi, Zsolt Ujvári

“…Ha az igazságügyi vagy eseti rovarszakértő sikeresen azonosítja a fajt, az segíti az adott méregre specifikus IgE allergológiai vizsgálatát. Érték: A rovarcsípés okozta anafilaxia eredményeképp bekövetkező halál oka az esetek többségében a kellő körültekintés, valamint a megfelelő módszerek hiányában nem került megállapításra. …”
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Preventive effects of Bifidobacterium lactis Probio-M8 on ovalbumin-induced food allergy in mice by Jialu Shi, Yan Xu, Cheng Liu, Shizhi Wang, Jin Wang, Vijaya Raghavan

“…Results demonstrate that oral administration of Probio-M8 effectively mitigated the allergy symptoms triggered by ovalbumin (OVA) by ameliorating the morphological damage in the jejunum, reducing OVA-specific IgE and histamine levels in the serum, and suppressing Th2 cytokines (interleukin (IL) 4 and IL-13) while increasing Th1 cytokines (interferon (IFN) γ) and regulatory T (Treg) cytokines (IL-10 and transforming growth factor (TGF) β1) in the culture supernatants of splenic cells. …”
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Synergistic Synbiotic-Containing <i>Lactiplantibacillus plantarum</i> and Fructo-Oligosaccharide Alleviate the Allergenicity of Mice Induced by Soy Protein by Jing Bai, Qian Zeng, Wen Den, Liheng Huang, Zhihua Wu, Xin Li, Ping Tong, Hongbing Chen, Anshu Yang

“…The results showed that Lp synergistic FOS significantly decreased clinical allergy scores, inhibited specific antibodies (IgE, IgG, and IgG1), IL-4, IL-6, and IL-17A levels, and increased IFN-γ and IL-10 levels. …”
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Sevoflurane Inhibits the Th2 Response and NLRP3 Expression in Murine Allergic Airway Inflammation by Lixia Wang, Binshan Zha, Qiying Shen, Hongyun Zou, Cheng Cheng, Huimei Wu, Rongyu Liu

“…We found that OVA-induced inflammatory cell recruitment to peribronchial regions, goblet cell hyperplasia, the serum levels of IgE, inflammatory cells, and the Th2 cytokine secretion in BALF was potently suppressed by sevoflurane with an efficacy comparable with that suppressed by MCC950 treatment. …”
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The Impact of Infectious Diseases on Clinical Characteristics and Immunological Correlations in Pediatric Henoch–Schönlein Purpura: A Five-Year Retrospective Study by Sînziana Oprițescu, Gabriela Viorela Nițescu, Mihaela Golumbeanu, Dora Boghițoiu, Elena Iuliana Ioniță, Diana-Andreea Ușurelu, Cristian Lucaci, Adriana Negoiță, Elena Moroșan

“…Measurements of immunological panels (IgA, IgM, IgG, and IgE), C3, C4, C-reactive protein, fibrinogen, and hematite sedimentation rate (VSH) determined using blood samples revealed that there is a strong correlation between the elements of the immunological panel and the HSP manifestations. …”
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Characterization of a chitinase from Trichinella spiralis and its immunomodulatory effects on allergic airway inflammation in mice by Jia Xu, Ye Yao, Qisheng Zhuang, Zixuan Li, Min Zhang, Shouan Wang, Hongxin Hu, Jianbin Ye

“…Additionally, rTs-chit treatment decreased the expression of GATA3, arginase-1, MCP-1, CCL-11, and AMCase, along with reducing OVA-specific IgE, IgG, and IgG1 levels, suggesting its potential as an immunomodulatory agent. …”
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Comparison of new secondgeneration H1 receptor blockers with some molecules; a study involving DFT, molecular docking, ADMET, biological target and activity by Velid Unsal, Erkan Oner, Reşit Yıldız, Başak Doğru Mert

“…The best binding sites of Desloratadine, Levocetirizine, Fexofenadine, CAPE, Quercetin, Melatonin, curcumin, Vitamin C ligands to Desmoglein 1, Human Histamine H1 receptor, IgE and IL13 protons were determined by molecular docking method and binding energy and interaction states were analyzed. …”
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Clinical Guidelines of the Russian Gastroenterological Association on the Diagnostics and Treatment of Eosinophilic Esophagitis by V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, T. L. Lapina, D. N. Andreev, E. K. Baranskaya, A. S. Tertychny, S. S. Pirogov, A. A. Sheptulin, D. I. Abdulganieva, D. T. Dicheva, A. V. Zaborovsky, N. Yu. Ivashkina, N. V. Korochanskaya, A. V. Paraskevova

“…The diagnostic criterion is the eosinophilic infiltration of the esophageal mucosa with an eosinophil density of ≥ 15 per high power field (×400) in at least one of the biopsy specimens (about 60 eosinophils in 1 mm2). Total IgE levels, peripheral blood eosinophilia and skin allergy tests are considered to be additional diagnostic means. …”
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姜黄素通过抑制p38 MAPK和AKT活化改善幼鼠过敏性气道炎症 by 陈彦球, 陈彬林, 马百会, 曾清香, 刘文龙, 宋丰林

“…在末次卵清白蛋白激发24 h后，观察各组小鼠的症状，测定肺泡灌洗液（BALF）中的炎症细胞数，全血细胞分 析白细胞亚型的数量，用HE染色观察肺部支气管周围炎症细胞浸润情况，用过碘酸-雪夫染色观察杯状细胞增生情况，酶 联免疫吸附法测定BALF中的细胞因子IL-4、IL-5、IL-13以及血浆中的总IgE水平，western blot技术检测肺组织磷酸化p38 丝裂原活化蛋白激酶（p-p38 MAPK）/p38 MAPK,，p-AKT/AKT蛋白表达情况。…”
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Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities by Ammara Riaz, Azhar Rasul, Ghulam Hussain, Muhammad Kashif Zahoor, Farhat Jabeen, Zinayyera Subhani, Tahira Younis, Muhammad Ali, Iqra Sarfraz, Zeliha Selamoglu

“…It carries out the aforementioned activities by the regulation and modulation of various molecular targets such as transcription factors (NF-κB, TNF-α, and TGF-β1), enzymes (iNOS, COX-2, PGE2, MMP-1, MMP-3, MIP-1α, COX-2, PGE-2, HK2, AChe, SOD, DRP-1, DDH, PLCγ1, and GPX), kinases (JNK, MAPK, Akt, ERK, SAPK, IκBα, PI3K, and PKCβ2), cell adhesion proteins (E-cadherin, vimentin PAR-2, and NCam), apoptotic and antiapoptotic proteins (Beclin-1, Bcl-2, Bax, Bcl-xL, cytochrome c, LC3A/B, caspase-3, caspase-9, procaspase-3, procaspase-8, and IgE), and inflammatory cytokines (SOCS-3, SOCS-5, IL-1β, IL-4, IL-6, IL-8, IL-13, MCP-1, CXCL-1, CXCL-2, and IFN-γ). …”
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Role and sensitivity of Positron Emission Tomography with [18F]Fluorodeoxyglucose in diagnosis and follow-up of patients affected by chronic pulmonary aspergillosis (CPA) by Gianfranco Schiraldi, Cristina Elena Popescu, Michele Chiericozzi, Salvatore Lo Cicero, Flavio Allegri, Franco Mosca, Claudio Rossetti

“…., identification of Aspergillus-specific IgE and IgG antibodies using IFA and ELISA). 12 months after the treatment, we repeated tests only in patients with possible active disease to make a comparison between serological tests and 18F-FDG PET/CT. …”
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Chronic Rhinosinusitis without Nasal Polyps in Asian Patients Shows Mixed Inflammatory Patterns and Neutrophil-Related Disease Severity by Dae Woo Kim, Kyoung Mi Eun, Eun Youn Roh, Sue Shin, Dong-Kyu Kim

“…When comparing the UPs between groups, CRSsNP patients showed higher levels of Th2 cytokines (IL-4 and IL-13), eosinophilic chemokines (CCL-11 and CCL-24), ECP, and total IgE expression than control subjects. In addition, several neutrophilic markers (IL-1α, IL-6, IL-8, CXCL-1, CXCL-2, and MPO), IL-17A, IL-22, and TNF-α were dominant in CRSsNP patients. …”
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Co-Occurrence of Rarest Type of Dysphagia Lusoria (Type N-1) and Eosinophilic Esophagitis in a Cognitively Disabled Individual by Kishore Kumar, Jasbir Makker, Hassan Tariq, Ariyo Ihimoyan, Chime Chukwunonso, Masooma Niazi, Michael Lombino, Muhammad Kamal, Harish K. Patel

“…There was no laboratory evidence of peripheral eosinophilia. The IgE-mediated allergic test was unremarkable. His prior presentation revealed a diagnosis of eosinophilic esophagitis. …”
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Milk fat globule membrane supplementation protects against β-lactoglobulin-induced food allergy in mice via upregulation of regulatory T cells and enhancement of intestinal barrier... by Han Gong, Tiange Li, Dong Liang, Jingxin Gao, Xiaohan Liu, Xueying Mao

“…Results demonstrated that MFGM alleviated food allergy symptoms, decreased serum levels of lipopolysaccharide, pro-inflammatory cytokines, immunoglobulin (Ig) E, IgG1, and Th2 cytokines including interleukin (IL)-4, while increased serum levels of Th1 cytokines including interferon-γ and regulatory T cells (Tregs) cytokines including IL-10 and transforming growth factor-β. …”
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March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation by Osama A. Kishta, Antoine Sabourin, Leora Simon, Toby McGovern, Maxime Raymond, Tristan Galbas, Abdelilah Majdoubi, Satoshi Ishido, James G. Martin, Jacques Thibodeau

“…Interestingly, in the serum, levels of total and ova-specific IgE were reduced in March1-deficient mice as compared to WT mice. …”
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A nomogram for predicting bladder dysfunction in patients with type 2 diabetes mellitus: a retrospective study by Yingjie Hu, Fengming Hao, Ying Wang, Ling Chen, Lihua Wen, Jue Li, Wei Ren, Wenzhi Cai

“…Multivariate logistic regression analysis identified HbA1c, PCP-2h, DPN, TCO2, PAB, T-Bil, I-Bil, IgE, URBC, UI and UR as independent risk factors for DBD. …”
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广东地区成人外周血嗜酸性粒细胞检测对嗜酸性粒细胞性鼻息肉的诊断意义 by 孔维封

“…【结果】广东地区成年人患者嗜酸性粒细胞性鼻息肉占36.1%，非嗜酸性粒细胞性鼻息肉占63.9%，嗜酸性粒细胞性鼻息肉组在合并变应性鼻炎比例、合并哮喘比例、外周血IgE水平、双侧后组筛窦总分、筛窦上颌窦比值、外周血嗜酸性粒细胞绝对值及百分比、嗜碱性粒细胞绝对值及百分比等指标较非嗜酸性粒细胞性鼻息肉更高，差异有统计学意义。…”
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Increase of Vascular Endothelial Growth Factor and Decrease of MCP-1 and Some Updated Epidemiology Aspects of Cystic Echinococcosis Human Cases in Calabria Region by Giovanni Matera, Maria Teresa Loria, Cinzia Peronace, Tatiana Catanzariti, Pio Settembre, Aida Giancotti, Angelo G. Lamberti, Giorgio S. Barreca, Luisa Galati, Gessica Dodaro, Maria Mazzitelli, Alessio Strazzulla, Carlo Torti, Angela Quirino, Maria Carla Liberto, Alfredo Focà

“…An increase of serum total IgE class and IgG4 subclass was found in Echinococcus-positive patients versus controls. …”
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