嗜酸性淋巴肉芽肿的免疫病理研究

“…用免疫组织化学方法及组织化学特殊染色法观察35例嗜酸性淋巴肉芽肿病变组织中的lgE、IgA、IgM、IgG抗体和肥大细胞,结果表明,病变组织中IgE明显增多,主要分布在淋巴滤泡生发中心内及生发中心外浆细胞内,肥大细胞大量增生,其分布及数量与一般的慢性炎症组织明显不同。…”
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Evaluation of Haematological and Immunological Status in Type 2 Diabetics by A. Sohna Chandra Packiavathy, M. Ramalingam

“…The values of IgG, IgM, IgE and IgA were found to be significantly increased. …”
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Allergic diseases, drug adverse reactions and total immunoglobulin E levels in lupus erythematosus patients by Anna Wozniacka, Anna Sysa-Jedrzejowska, Ewa Robak, Zbigniew Samochocki, Malgorzata Zak-Prelich

“…Background: The association of allergic diseases, drug adverse reactions and elevated total immunoglobulin E (IgE) concentration in systemic lupus erythematosus patients remains controversial. …”
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Three Unrelated Patients of Roma Ethnicity from a Single Center Carrying the Same Deletion in <i>MYD88</i> Gene: A Founder Effect? by Roberta Romano, Francesca Cillo, Laura Grilli, Alessio Ciaccio, Lorenzo Bufalo, Elisabetta Toriello, Antonio De Rosa, Carmen Rosano, Emilia Cirillo, Giancarlo Blasio, Marika Comegna, Carmela Di Domenico, Giuseppe Castaldo, Claudio Pignata, Giuliana Giardino

“…Moreover, being associated with increased Immunoglobulin E (IgE) levels, this condition should be included in the differential diagnosis of Hyper-IgE syndromes.…”
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Human inborn errors of immunity underlying Talaromyces marneffei infections: a multicenter, retrospective cohort study by Huifeng Fan, Zhiyong Yang, Yuhui Wu, Xiulan Lu, Tian Li, Xuyang Lu, Gen Lu, Liming He, Guoping Lu, Li Huang

“…Three cases presented with pan-hypogammaglobulinemia, while three other cases showed heightened levels of IgM. Elevated levels of IgE were detected in five cases, and six cases exhibited decreased T lymphocyte absolute counts. …”
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珠三角地区变应性鼻炎和/或支气管哮喘患者皮下特异性免疫治疗依从性的真实世界研究 by 江育蔺, 王心悦, 唐隽, 鲍燕敏, 王桂兰, 白珺, 廖振鹏, 黎雅婷

“…结果纳入1 244例接受SCIT的患者，中止治疗427例（脱落率为34.3%）；儿童、已婚、过敏家族史阳性、总IgE （tIgE）&gt;200 U/mL的患者表现出相对良好的SCIT依从性（<italic>P</italic>值均&lt;0.05），而单纯AR患者依从性较AR合并BA组低（<italic>P</italic>&lt;0.05），治疗前症状评分和药物评分高的患者脱落率低（<italic>P</italic>值均&lt;0.001）。…”
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Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis by Zheng H, Xu S, Yang R, Jiao WE, Qiao YL, Liu JY, Fan HM, Zhou YT, Ni HF, Chen J, Deng YQ, Chen SM

“…In AR patients, circulating IgA+CD27- class-switched memory B cells were significantly positively correlated with Treg cells, IL-10, and IL-4 and significantly negatively correlated with IFN-γ, total IgE, sIgE, and VAS scores (P < 0.05). After AIT, the number of circulating IgA+CD27- class-switched memory B cells in AR patients was significantly positively correlated with the number of Treg cells and IL-10 and significantly negatively correlated with the VAS score (P < 0.05).Conclusion: The IgA+CD27- class-switched memory cell subset in human peripheral blood may serve as a potential biomarker for evaluating AR symptoms and treatment efficacy. …”
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Plaque Rupture-Induced Myocardial Infarction and Mechanical Circulatory Support in Alpha-Gal Allergy by Sohab S. Radwan, Gauravpal Gill, Amre Ghazzal, Awais Malik, Christopher Barnett

“…Alpha-gal (AG) allergy is an IgE-mediated allergic reaction to galactose-alpha-1,3-galactose found in mammalian meat. …”
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The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma by Evelyn M. Slaughter, Nathan Boyer, Steven Bennett

“…This paper presents a case of hymenoptera venom anaphylaxis averted by omalizumab, a monoclonal antibody to IgE antibody. This case suggests a novel and unintentional effect of this therapy. …”
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Maillard reaction affecting immunobinding activity and digestibility of tropomyosin in Alectryonella plicatula food matrix by Chenchen Yu, Xinrong He, Nairu Ji, Shuai Kang, Dongxiao Li, Huilin Zhang, Yang Yang, Dong Lai, Qingmei Liu, Guangming Liu

“…In this study, the Maillard reaction with xylose significantly reduced the IgE binding capacity of Alectryonella plicatula food matrix (AFM), that reduced by (77.81 ± 2.68)%. …”
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Intravenous Immunoglobulins: Mode of Action and Indications in Autoimmune and Inflammatory Dermatoses by Lyubomir A. Dourmishev, Dimitrina V. Guleva, Ljubka G. Miteva

“…Intravenous immunoglobulins (IVIGs), a mixture of variable amounts of proteins (albumin, IgG, IgM, IgA, and IgE antibodies), as well as salt, sugar, solvents, and detergents, are successfully used to treat a variety of dermatological disorders. …”
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Kimura Disease Manifesting as Synchronous Bilateral Parotid Swelling in a Young Middle-Eastern Patient by Fatemah Faras, Fawaz Abo-Alhassan, Khalid Al-Sebeih, Jassem Bastaki

“…Characteristic features of the disease include, but not limited to, painless subcutaneous head and neck swelling, blood and tissue eosinophilia, and markedly elevated immunoglobulin E (IgE) levels. Herein, we report a rare case of Kimura disease manifesting as synchronous bilateral parotid swelling of 12 years duration in a 33-year-old Middle-Eastern man. …”
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Eosinophilic pancreatitis: a rare or unexplored disease entity? by Murli Manohar, Alok Verma, Gulshan Singh, Anil Mishra

“…EP patients also have elevated serum IgE levels with high eosinophil counts in the pancreas as well as in other organs such as the gastrointestinal tract, which is termed as eosinophilic gastroenteritis. …”
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Pathogenesis of Chronic Urticaria: An Overview by Sanjiv Jain

“…It is also probable that mast cells are involved in the pathogenesis through mechanisms that extend beyond high affinity IgE receptor stimulation. An increasing recognition of chronic urticaria as an immune mediated inflammatory disorder related to altered cytokine-chemokine network consequent to immune dysregulation resulting from disturbed innate immunity is emerging as yet another pathogenic explanation. …”
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Структура сенсибілізації до риби та морепродуктів у дітей by Yu.V. Marushko, O.D. Moskovenko, A.I. Chmil

“…Визначено рівні специфічних IgE до алергенів риби та морепродуктів. Результати. …”
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呼吸道菌群失调加重小鼠过敏性呼吸道炎症反应 by 王学坤, 张宗义, 王森林, 张梦媛, 王鹏程

“…建模成功后，应用相同的方法建立小鼠呼吸道菌群失调模型，在此基础上，通过腹腔注射致敏及雾化吸入卵清蛋白（OVA）激发，诱导小鼠过敏性呼吸道炎症反应，计数擦鼻频率，检测BALF中细胞总数及嗜酸性粒细胞百分比，肺组织病理分析炎症反应及杯状细胞增生情况，ELISA法检测血清中IgE水平，BALF中IFN-γ、IL-4、IL-5水平，血清、BALF 及肠组织中IL-33水平，从而分析呼吸道菌群失调对过敏性呼吸道炎症反应的影响。…”
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The Role of Immune Defects and Colonization of Staphylococcus aureus in the Pathogenesis of Atopic Dermatitis by Danuta Nowicka, Ewelina Grywalska

“…Moreover, anti-S. aureus-specific IgE was identified and measured in patients with AD, revealing that its level corresponds to the severity of the disease. …”
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Acute Eosinophilic Ascites in a Middle-Aged Man by Fadi Bleibel, Keith Fragoza, Garrey T. Faller

“…Initial work-up demonstrated severe peripheral blood eosinophilia, normal liver function tests, thickening of the stomach and small bowel wall, and elevated serum IgE. Upper endoscopy and extensive testing for malignancy and parasitic infections failed to establish a diagnosis. …”
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Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals by Ruxing Zhao, Yujing Sun, Yongyuan Zhang, Weili Wang, Shouyu Wang, Chuang Wang, Jinbo Liu, Ling Gao, Zhao Hu, Jianchun Fei, Xinguo Hou, Huizhen Zheng, Li Chen

“…Levels of C reactive protein, immunoglobulin (IgG, IgM, IgA, and IgE), and complements (C3, C4) were detected by rate nephelometry immunoassay. …”
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二甲双胍和孟鲁司特在急性和慢性过敏性哮喘小鼠模型中的作用 by 郭妍蓉, 严彦

“…结果慢性模型小鼠的血清总IgE水平、气道周围胶原沉积程度、气道平滑肌厚度显著高于急性模型小鼠（<italic>P</italic>＜0.05）。…”
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