Towards an ontology of mental health: Protocol for developing an ontology to structure and integrate evidence regarding anxiety, depression and psychosis [version 2; peer review: 1... by Jennifer Potts, Micaela Santilli, Claire Friedrich, Jaycee Kennett, Janna Hastings, Susan Michie, Paulina M. Schenk

“…Methods We will develop and apply the GALENOS Mental Health Ontology through eight steps: (1) defining the ontology’s scope; (2) identifying, labelling and defining the ontology’s entities for the GALENOS living systematic reviews; (3) structuring the ontology’s upper level (4) refining entities via iterative stakeholder consultations regarding the ontology’s clarity and scope; (5) formally specifying the relationships between entities in the Mental Health Ontology; (6) making the ontology machine-readable and available online; (7) integrating the ontology into the data repository; and (8) exploring the ontology-structured repository’s usability. …”
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Testing a multi-behavioral intervention to improve oral health behaviors in the pediatric dental surgery population: protocol for the PROTECT trial by Joanna Buscemi, Teresa G. Borowski, David Avenetti, Lisa Tussing-Humphreys, Lisa Tussing-Humphreys, Lisa Tussing-Humphreys, Molly Martin, Molly Martin, Marc S. Atkins, Teresa Marshall, Michael Berbaum, Helen H. Lee, Helen H. Lee

“…We developed PROTECT through an iterative process, incorporating feedback from caregivers, dentists, and community health workers and through a small pilot trial. …”
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Synthetic Data Generation and Evaluation Techniques for Classifiers in Data Starved Medical Applications by Wan D. Bae, Shayma Alkobaisi, Matthew Horak, Siddheshwari Bankar, Sartaj Bhuvaji, Sungroul Kim, Choon-Sik Park

“…We propose an incremental synthetic data generation system that improves data quality over iterations by gradually adjusting to the data distribution and thus avoids overfitting in classifiers. …”
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Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives by Bryan Cleal, Yanbing Chen, Mandy Wäldchen, Hanne Ballhausen, Drew Cooper, Shane O'Donnell, Christine Knoll, Niklas Krug, Klemens Raile, Tebbe Ubben, Adrian Tappe, Dana Lewis, Ingrid Willaing, Timothy Skinner, Katarina Braune

“…Narratives were thematically analyzed, and a coding framework was identified through iterative alignment. ResultsParticipants consistently reported improvements in glycemia, physical health, sleep quality, emotional impact on everyday life, and quality of life. …”
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State Estimation in Power Systems Under False Data Injection Attack Using Total Least Squares by Bamrung Tausiesakul, Krissada Asavaskulkiet, Chuttchaval Jeraputra, Ittiphong Leevongwat, Thamvarit Singhavilai, Supun Tiptipakorn

“…In this work, two non-iterative computation methods based on total least squares are proposed for estimating the state vector from the measurement results contaminated by the additive noise and the malicious attack that can arise in the power transmission systems. …”
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Education strategies are the most commonly used in pediatric rehabilitation implementation research: a scoping review by Sahar Ghahramani, Sophia C. Larson, Allison J. L’Hotta, Kelly M. Harris, Kim Lipsey, Elvin H. Geng, Lisa A. Juckett, Catherine R. Hoyt

“…The most commonly used implementation strategies were “train and educate key informant” (n = 21, 48%) and “use evaluative/iterative strategies” (n = 19, 43%). Feasibility (n = 19, 43%) and acceptability (n = 16, 36%) were the most frequently targeted implementation outcomes. …”
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Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma by Nan Li, Haiying Qin, Rosa Nguyen, Mitchell Ho, Ming Sun, Eytan Ruppin, Michael C Kelly, Yingying Cao, Reona Okada, Jeyshka M Reyes-González, Hannah G Stack, Charlie Seibert, Carol J Thiele

“…We developed a new chimeric antigen receptor (CAR) targeting glypican-2 (GPC2) and conducted iterative preclinical engineering of the CAR structure to maximize its anti-tumor efficacy before clinical translation.Methods We evaluated different GPC2-CAR constructs by measuring the CAR activity in vitro. …”
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Conceptualising cultural safety at an Indigenous-focused midwifery practice in Toronto, Canada: qualitative interviews with Indigenous and non-Indigenous clients by Michelle Firestone, Sara H Wolfe, Cheryllee Bourgeois, Janet K Smylie, Mackenzie E Churchill, Helle Moeller

“…Interviews were transcribed and analysed thematically using an iterative, consensus-based approach and a critical, naturalistic, and decolonising lens.Participants Saturation was reached after 20 interviews (n=9 Indigenous participants, n=11 non-Indigenous participants).Results Three domains of cultural safety emerged. …”
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Combining exergy-pinch and techno-economic analyses for identifying feasible decarbonization opportunities in carbon-intensive process industry: Case study of a propylene productio... by Tharun Roshan Kumar, Johanna Beiron, V.R. Reddy Marthala, Lars Pettersson, Simon Harvey, Henrik Thunman

“…The framework combines an iterative exergy-pinch analysis with techno-economic analysis to identify promising process modifications. …”
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A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study by Lauren Kelenc, Brittany Wiles, Fareha Nishat, Chitra Lalloo, Anya Nair, Craig Eling, Melanie Kirby-Allen, Ewurabena Simpson, Roona Sinha, Richard Ward, William T. Zempsky, Sara Ahola Kohut, Jennifer N. Stinson

“…Conclusion: The results from this pilot study suggest that the current iteration of the iP2P SCD program lacks feasibility. …”
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A sensitivity analysis of methodological variables associated with microbiome measurements by Samuel P. Forry, Stephanie L. Servetas, Jennifer N. Dootz, Monique E. Hunter, Jason G. Kralj, James J. Filliben, Scott A. Jackson

“…This report details a full factorial exploration of 48 experimental protocols by systematically varying microbiome sample, iterations of material production, laboratory personnel, DNA extraction kit, marker gene selection, and reference databases. …”
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Why and how should we simulate platform trials? Learnings from EU-PEARL by Elias Laurin Meyer, Tobias Mielke, Marta Bofill Roig, Michaela Maria Freitag, Peter Jacko, Pavla Krotka, Peter Mesenbrink, Tom Parke, Sonja Zehetmayer, Dario Zocholl, Franz König

“…We developed and proposed an iterative, simulation-guided “vanilla and sprinkles” framework, i.e. from a basic to a more complex design, for designing platform trials. …”
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Complex Cloud-Sea Background Simulation for Space-Based Infrared Payload Digital Twin by Wen Sun, Yejin Li, Fenghong Li, Guangsen Liu, Peng Rao

“…Static cloud-sea scenes are generated using Qilu-2 and New Technology satellite images, while dynamic scenarios are simulated with our iterative fractal dimension optimization algorithm. …”
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Dynamic assessment of long-term survival in survivors with stage III non-small cell lung cancer: a novel conditional survival model with a web-based calculator by Xiangdi Meng, Xiangdi Meng, Peihe Wang, Jie Liu, Daqing Sun, Zhuojun Ju, Yuanyuan Cai

“…The model performed with an excellent concordance index (C-index) of 0.71 (95% CI: 0.70–0.72), and a median time-dependent AUC of 0.71–0.73 from 200 iterations 5-fold cross-validation.ConclusionThe study demonstrated the improvement in real-time OS over time in stage III NSCLC survivors and developed the novel CS-nomogram to provide patients with updated survival data. …”
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Exploring the Needs and Preferences of Users and Parents to Design a Mobile App to Deliver Mental Health Peer Support to Adolescents With Type 1 Diabetes: Qualitative Study by Titilola I Yakubu, Poonamdeep Jhajj, Samantha Pawer, Nicholas C West, Shazhan Amed, Tricia S Tang, Matthias Görges

“…A thematic analysis following an inductive and iterative process was performed to develop themes and subthemes from the collected information. …”
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Machine Learning and Intelligent Diagnostics in Dental and Orofacial Pain Management: A Systematic Review by Taseef Hasan Farook, Nafij Bin Jamayet, Johari Yap Abdullah, Mohammad Khursheed Alam

“…Machine learning in dental and orofacial healthcare has shown respectable results in diagnosing diseases with symptomatic pain and with improved future iterations and can be used as a diagnostic aid in the clinics. …”
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Implementation of Distributed Generation with Solar Plants in a 132 kV Grid Station at Layyah Using ETAP by Ghulam Mujtaba, Zeeshan Rashid, Farhana Umer, Shadi Khan Baloch, G. Amjad Hussain, Muhammad Usman Haider

“…To overcome this issue, a simulation of load flow of this system is performed using the Newton-Raphson method due to its less computational time, fewer iterations, fast convergence, and independence from slack bus selection. …”
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Translation, adaptation and validation of an epilepsy screening instrument in two Ghanaian languages. by Emmanuel Kwame Darkwa, Sabina Asiamah, Elizabeth Awini, Cynthia Sottie, Anthony Godi, John E Williams, Albert Akpalu, J Helen Cross, Josemir W Sander, Arjune Sen, Charles R Newton, Anthony Danso-Appiah, Patrick Adjei

“…It can also be adapted for other resource-poor settings, although translation and iterative in-country testing will be needed to ensure its validity.…”
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Comparison of principal component analysis algorithms for imputation in agrometeorological data in high dimension and reduced sample size. by Valter Cesar de Souza, Sergio Augusto Rodrigues, Luís Roberto Almeida Gabriel Filho

“…The aim of this study was to evaluate the performance of alternative multivariate procedures for principal component analysis (PCA), using the Nonlinear Iterative Partial Least Squares (NIPALS) and Expectation-Maximization (EM) algorithms, for imputing missing data in time series of meteorological variables. …”
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Negotiating a physically active life in tune with ageing: a grounded theory study of older persons’ experiences of participating in high-intensity interval training by Helena Fridberg, Maria Wiklund, Fredrik Snellman, Erik Rosendahl, Mattias Hedlund, Carl-Johan Boraxbekk, Nina Lindelöf

“…The focus groups were analysed inductively, followed by an iterative process of abstraction, abduction, and theory generation using a constant comparative method. …”
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