Medication patterns and potentially inappropriate medication in patients with metastatic breast cancer: results of the BRE-BY-MED study by Lilly Sophia Brandstetter, Anna Grau, Peter U. Heuschmann, Max Müller-Reiter, Jessica Salmen, Stefan Störk, Achim Wöckel, Jens-Peter Reese

“…Methods Between July 2022 and February 2024 individuals with advanced or mBC, aged ≥ 18 years, living in Bavaria, and who gave written informed consent, were included in the BRE-BY-MED “Breast Cancer Care in Bavaria for Patients with Metastatic Disease” cohort study (DRKS00026601). …”
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Comparative Study on Growth Characteristics and Early Selection Efficiency of Hybrid Offspring of <i>Populus deltoides</i> ‘DD-109’ and <i>P. maximowiczii</i> in Liaoning, China... by Wei Liu, Chenggong Liu, Yan Zhang, Jinhua Li, Jiabao Ji, Xiaorui Qin, Fenfen Liu, Chengcheng Gao, Nairui Wang, Xueli Zhang, Ning Liu, Rusheng Peng, Qinjun Huang

“…These findings contribute to evaluating the production potential of <i>P. deltoides</i> ‘DD-109’ and <i>P. maximowiczii</i> germplasm in northern China and provide valuable guidance for selecting poplar clones suitable for local cultivation, accelerating breeding processes, and informing management planning for poplar plantations.…”
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Bacterial etiologies, antimicrobial susceptibility profiles and associated factors among patients with otitis media referred to Nekemte Public Health Research and Referral Laborato... by Endalu Tesfaye Guteta, Fedasan Alemu Abdi, Seifu Gizaw Feyisa, Betrearon Sileshi Kinfu, Tadese Bekele Tafesse

“…Currently, there is little information on the prevalence and antimicrobial susceptibility patterns of pathogenic bacterial isolates from patients with otitis media in Ethiopia. …”
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Cocoa farmers' characteristics on climate variability and its effects on climate change adaptation strategy by I. Idawati, N.A. Sasongko, A.D. Santoso, M. Septiani, T. Handayani, A.Y.N. Sakti, B.D. Purnamasari

“…The sample size was determined using the Slovin formula through in-depth interviews with five key informants. The data collected were descriptively and statistically analyzed using the Excel program, which involved generating frequency distribution tables. …”
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Influencing factors and changing trends of depressive symptoms among middle and junior high school students in Eastern China from 2019 to 2023: a cross-sectional study by Xingchen Zhu, Na An, Zaixiang Tang, Jianping Huang, Qingxin Ren, Yue Wu

“…Students were administered an online survey, completed the Chinese version of the Center for Epidemiologic Studies Depression Scale, and answered questions regarding basic information, such as birth date. Univariate and multivariate analyses were performed to examine the factors that influenced depressive symptoms. …”
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Benefits, limits, and risks of ChatGPT in medicine by Jonathan A. Tangsrivimol, Jonathan A. Tangsrivimol, Erfan Darzidehkalani, Hafeez Ul Hassan Virk, Zhen Wang, Zhen Wang, Jan Egger, Michelle Wang, Sean Hacking, Benjamin S. Glicksberg, Markus Strauss, Markus Strauss, Chayakrit Krittanawong, Chayakrit Krittanawong

“…To aid in understanding and progress, our analysis is organized into six key areas: (1) Information and Education, (2) Triage and Symptom Assessment, (3) Remote Monitoring and Support, (4) Mental Healthcare Assistance, (5) Research and Decision Support, and (6) Language Translation. …”
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Surgical options for Evans-Jensen type IV intertrochanteric femur fractures in the elderly over 65: a comparison between total hip arthroplasty and proximal femoral nail antirotati... by Ming Sun, Hai-Rui Liang, He Zhang, Tong Bai, Rong-Da Xu, Si-Yu Duan, Zhen-Cun Cai, Zhen-Cun Cai

“…The patients were divided into two groups based on the treatment method: the PFNA group (20 cases) and the THA group (20 cases). General patient information, operative time, intraoperative blood loss, time to postoperative mobilization, time to weight-bearing on the affected limb, Harris hip scores at 1, 3, and 6 months postoperatively, excellent and good rates, SF-36 scores, and postoperative complications were recorded.ResultsCompared to the PFNA group, the THA group had a longer operative time (86.7 ± 9.6 vs. 51.5 ± 5.3 min, p &lt; 0.001) and more intraoperative blood loss (212.0 ± 35.5 vs. 76.5 ± 16.1 ml, p &lt; 0.001). …”
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Current regenerative approaches to the treatment of generalized periodontitis in young people (literature review) by O.V Kopchak, I.V. Kovach, Y.V. Litvinova, K.A. Yanishevsky, N.S. Marchenko

“…The conducted analysis included studies whose findings were published in 52 English- and Ukrainian-language information sources for the period 1985-2022. The literature search was carried out in the PubMed, Scopus, Google Scholar databases and in the electronic catalog of the National Scientific Medical Library of Ukraine. …”
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Identification of patient demographic, clinical, and SARS-CoV-2 genomic factors associated with severe COVID-19 using supervised machine learning: a retrospective multicenter study by Kuganya Nirmalarajah, Patryk Aftanas, Shiva Barati, Emily Chien, Gloria Crowl, Amna Faheem, Lubna Farooqi, Alainna J. Jamal, Saman Khan, Jonathon D. Kotwa, Angel X. Li, Mohammad Mozafarihashjin, Jalees A. Nasir, Altynay Shigayeva, Winfield Yim, Lily Yip, Xi Zoe Zhong, Kevin Katz, Robert Kozak, Andrew G. McArthur, Nick Daneman, Finlay Maguire, Allison J. McGeer, Venkata R. Duvvuri, Samira Mubareka

“…Results Complete clinical data and viral whole genome level information were obtained from 617 patients, 50.4% of whom were hospitalized. …”
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Large-scale spatio-temporal variation in vital rates and population dynamics of an alpine bird by Nater, Chloé R., Frassinelli, Francesco, Martin, James A., Nilsen, Erlend B.

“…Our study highlights the potential of participatory monitoring and 2integrated modelling approaches for estimating and understanding spatio-temporal patterns in species abundance and demographic rates, and showcases how corresponding workflows can be set up in reproducible and semi-automated ways that increase their usefulness for informing management and regular reporting towards national and international biodiversity frameworks.…”
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Aerobic exercise alleviates statin-induced PCSK9 upregulation by increasing epoxyeicosatrienoic acid levels through the FoxO3a–Sirt6 axis by Jiahui Hu, Hao Lei, Jingyuan Chen, Leiling Liu, Yajun Gui, Kaijun Sun, Danyan Xu

“…Further, EETs significantly suppressed PCSK9 expression, subsequently reducing the LDL-C levels (all p < 0.05); this effect was mediated via the activation of the forkhead box O3a–silent mating type information regulation 2 homolog 6 (FoxO3a–Sirt6) axis, with no impact on the sterol regulatory element binding protein 2 and 3-hydroxy-3-methylglutaryl-CoA reductase (SREBP2-HMGCR) pathway. …”
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Sustainability assessment of animal feed production from by-products of Sago palm smallholder industry by Allaily ., A.D. Santoso, M.N. Rofiq, N.A. Sasongko, H. Daulay, E.I. Wiloso, E. Widjaja, B.N. Utomo, A.I. Yanuar, S. Suryani, Y.P. Erlambang, U.N. Thiyas, D. Iskandar, A. Anhar, M. Rahmawati, T. Simamora, Y. Yusriani, G. Maghfirah, M. Ammar

“…This study provided information that production factors needed to be improved for sustainability of Sago palm smallholder industry in terms of economy and environment. …”
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Using microfluidic shear to assess transfusion requirements in trauma patients by Rachael A Callcut, James T Ross, Anamaria J Robles, Leslie H Vuoncino, Ashli C Barnes, Leonardo W Graeff, Taylor L Anway, Nico T Vincent, Nithya Tippireddy, Kimi M Tanaka, Randi J Mays

“…We hypothesize the CA and PCF from this novel assay will provide information that correlates with trauma-induced coagulopathy and transfusion requirements.Methods Blood samples were collected on adult trauma patients from a single-institution prospective cohort study of high-level activations. …”
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Characterizing local forest structural complexity based on multi-platform and -sensor derived indicators by Patrick Kacic, Ursula Gessner, Christopher R. Hakkenberg, Stefanie Holzwarth, Jörg Müller, Kerstin Pierick, Dominik Seidel, Frank Thonfeld, Michele Torresani, Claudia Kuenzer

“…In this regard, forest managers have sought to promote enhanced structural complexity (ESC) which utilizes the positive correlation between structural complexity and biodiversity or resilience to inform management practices. In light of these concerns, we integrated remote sensing data from multiple platforms and sensors to test the potential for quantifying different levels of structural complexity in temperate forests. …”
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Fetal Spinal Cord Tissue in Mini-Guidance Channels Promotes Longitudinal Axonal Growth after Grafting into Hemisected Adult Rat Spinal Cords by Norman I. Bamber, Huaying Li, Patrick Aebischer, Xiao Ming Xu

“…We conclude that viable FSC grafts within semipermeable guidance channels may serve both as a permissive bridge for longitudinally directed axonal growth and a potential relay for conveying information across a lesion site in the adult rat spinal cord.…”
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RETRACTED ARTICLE: Bone mesenchymal stem cell-derived exosomal microRNA-7-5p inhibits progression of acute myeloid leukemia by targeting OSBPL11 by Duanfeng Jiang, Xin Wu, Xiaoying Sun, Wei Tan, Xin Dai, Youbang Xie, Ashuai Du, Qiangqiang Zhao

“…Conclusions Exo-miR-7-5p derived from BMSCs negatively regulates OSBPL11 by suppressing the phosphorylation of the PI3K/AKT/mTOR signaling pathway, thereby inhibiting AML proliferation and promoting apoptosis. The data will inform the development of AML therapies based on BMSC-derived exosomes. …”
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Altered Topological Properties of Grey Matter Structural Covariance Networks in Complete Thoracic Spinal Cord Injury Patients: A Graph Theoretical Network Analysis by Wen-Li Wang, Yu-Lin Li, Mou-Xiong Zheng, Xu-Yun Hua, Jia-Jia Wu, Fei-Fei Yang, Nan Yang, Xia He, Li-Juan Ao, Jian-Guang Xu

“…The efficiency of regional information transmission in psychology-cognition regions increased. …”
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Review: A systematic review of dairy cow health, welfare, and behaviour in year-round loose range housing by W.J. Harvey, L. Petrokofsky, M.W. Jordon, G. Arnott, L.W. von Walter, A. Malik, T. Carter, L.S. Wade, G. Petrokofsky

“…To contribute to evidence-informed policy, a systematic evidence evaluation was undertaken to assess the scientific evidence base for this question, and determine whether the evidence base is robust enough to determine any association between housing systems and health, welfare and natural behaviour in dairy cows. …”
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The ASK-16 motorized glider: an airborne eddy covariance platform to measure turbulence, energy, and matter fluxes by I. Wiekenkamp, A. K. Lehmann, A. Bütow, J. Hartmann, S. Metzger, S. Metzger, T. Ruhtz, C. Wille, M. Zöllner, T. Sachs, T. Sachs

“…<p>Airborne eddy covariance measurements can bridge the gap between local (tower-based) and regional (satellite/inversion-derived) flux data, as they provide information about the spatial distribution of turbulent fluxes for larger regions. …”
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Using Community Engagement to Create a Telecoaching Intervention to Improve Self-Management in Adolescents and Young Adults With Cystic Fibrosis: Qualitative Study by Christina L Duncan, Emily F Muther, Jennifer J Lindwall, Kristine Durkin, Elizabeth Ruvalcaba, Eliza Williamson, Corrine Ahrabi-Nejad, Evelyn Bord, Angela Green, Megan L Harrison, Deepika Polineni

“…Our Step 1 qualitative findings helped inform the structure (eg, telecoaching session frequency and duration) and approach of the telecoaching intervention. …”
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