The anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01E by M. Sanni Ali, Lisa Stockdale, Issaka Sagara, Issaka Zongo, Rakiswendé Serge Yerbanga, Almahamoudou Mahamar, Frédéric Nikièma, Amadou Tapily, Frédéric Sompougdou, Modibo Diarra, Duncan Bellamy, Samuel Provstgaard-Morys, Charles Zoungrana, Djibrilla Issiaka, Alassane Haro, Koualy Sanogo, Abdoul Aziz Sienou, Mahamadou Kaya, Seydou Traore, Oumar M. Dicko, Youssouf Kone, Hama Yalcouye, Ismaila Thera, Kalifa Diarra, Paul Snell, Opokua Ofori-Anyinam, Chris Ockenhouse, Cynthia Lee, Katie Ewer, Halidou Tinto, Abdoulaye Djimde, Jean-Bosco Ouedraogo, Alassane Dicko, Daniel Chandramohan, Brian Greenwood

“…However, there is little information about the immune response to repeated booster doses of RTS,S/AS01E. …”
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CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma by Victoria Jennings, Kevin Harrington, Hardev Pandha, Alan Melcher, Adel Samson, Fiona Errington-Mais, Victoria Roulstone, Eva Crespo-Rodriguez, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Martin McLaughlin, Malin Pedersen, Richard Vile, Joan Kyula, Jehanne Hassan, Lizzie Appleton, Charleen ML Chan Wah Hak, Gabby Baker, Edward Armstrong, Matthew Chiu, Masahiro Ono

“…This immune data was used to inform the selection of ICI for triple combination therapy, the effects of which were then further characterized using transcriptomics.Results Adding BRAFi treatment to HSV improved anti-tumor effects in vivo but not in vitro. …”
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Preliminary study assessing the long-term surgical outcomes of TBX6-associated congenital scoliosis (TACS) patients using the propensity score matching method: exploring the clinic... by Guanfeng Lin, Yang Yang, Zefu Chen, Sen Zhao, Yuchen Niu, You Du, Yiwei Zhao, Shengru Wang, Nan Wu, Jianguo Zhang

“…We evaluated and compared the coronal and sagittal radiographic parameters before surgery, immediately after surgery, and at the final follow-up. Surgical information, including surgical method, fusion segment, blood loss and complications, was also compared and analyzed. …”
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Four-dimensional flow magnetic resonance imaging for noninvasive diagnosis of clinically significant portal hypertension and high-risk gastroesophageal varices in patients with cir... by Jiachen Ji, Yi Xiang, Jinghui Dong, Hanyu Jiang, Tianyi Xia, Yunduo Li, Mengmeng Zhang, Changchun Liu, Xijun Gong, Bo Jin, Wen Shen, Gangfeng Zhu, Jianming Cai, Rui Li, Xiaolong Qi

“…Four-dimensional (4D) flow magnetic resonance imaging (MRI) provides comprehensive flow information and is a promising alternative. This study evaluated the efficacy of 4D flow MRI as a noninvasive method for diagnosing CSPH and high-risk varices in patients with liver cirrhosis. …”
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Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers by Beatrice Brunner, Andrea Martina Aegerter, Venerina Johnston, Thomas Volken, Manja Deforth, Gisela Sjøgaard, Achim Elfering, Markus Melloh, the NEXpro Collaboration Group

“…The 12-week multi-component intervention consisted of neck exercises, health promotion information workshops, and workplace ergonomics sessions. …”
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Deep learning-based algorithm for classifying high-resolution computed tomography features in coal workers’ pneumoconiosis by Hantian Dong, Biaokai Zhu, Xiaomei Kong, Xuesen Su, Ting Liu, Xinri Zhang

“…This successful application of a deep learning-data augmentation algorithm can help clinical radiologists by providing reliable diagnostic information for classification. Trial registration: Chinese Clinical Trial Registry, ChiCTR2100050379. …”
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The impact of implementing and sustaining the international guidelines for skin-to-skin contact in the first hour after birth in Uganda by Kajsa Brimdyr, Scovia Nalugo Mbalinda, Anna Blair, Kristin Svensson, Mike Kagawa, Melissa Reyes, Louise Racine Bastarache, Livingstone Kamoga, Edwin Kigozi, Karin Cadwell

“…Interactive Analysis Labs allowed key informants to provide reflection on barriers and solutions. …”
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Quality of life and its influencing factors in patients with gynecologic tumor (妇科肿瘤患者生存质量现状及影响因素调查研究) by CHEN Fan (陈帆), GUO Xiujing (郭秀静), CHEN Jing (陈静)

“…Methods Patients with gynecologic malignant tumor in a grade-A hospital in Sichuan province were selected as the research objects. The general information questionnaire, EORTC Quality of Life Questionnaire (EORTC QLQ-30), Chinese version of the European Organization for Research and Treatment for Cancer Quality of Life Questionnaire-spiritual Well-being (EORTCQLQ-SWB32) and the Hospital Anxiety and Depression Scale(HAD) were used in the survey. …”
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Progressive subchondral bone cyst formation following autologous chondrocyte implantation with all-suture anchors: a Case Report with histological evaluation by Takuma Kaibara, Eiji Kondo, Masatake Matsuoka, Koji Iwasaki, Tomohiro Onodera, Daisuke Momma, Zen-Ichi Tanei, Shinya Tanaka, Norimasa Iwasaki

“…These observations may inform future strategies for the early detection of SBC formation and its progression, as well as timely intervention to prevent further joint damage in similar cases, though further research is needed to establish broader clinical implications.…”
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Long-term impact of different prevalent cropping systems on soil physico-chemical characteristics under subtropical climate conditions of Punjab, Pakistan by Fahad Ali Fayyaz, Irfan Aziz, Muhammad Ansar, Muhammad Akmal, Saud Alamri, Alanoud T. Alfagham, Renata Gamrat, Abdul Qayyum

“…Abstract Lack of site-specific nutrients information for different cropping systems has been a major challenge in addressing declining soil fertility levels and enhance crop productivity in Punjab, Pakistan. …”
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Attitudes toward scale-up of an Intensive Combination Approach to Rollback the Epidemic in Nigerian adolescents (iCARE) intervention for youth in Nigeria: results of a mixed method... by Arthi Kozhumam, Revika Singh, Oche Agbaji, Adedotun Adetunji, Bopo Taiwo, Olayinka Omigbodun, Kehinde Kuti, Agatha David, Sulaimon Akanmu, Folashade Adekambi, Akinsegun Akinbami, Bibilola Oladeji, Babafemi Taiwo, Lisa M. Kuhns, Ogochukwu Okonkwor, Baiba Berzins, Amy K. Johnson, Titilope Badru, Patrick Janulis, Olubusuyi M. Adewumi, Marbella Cervantes, Olutosin Awolude, Robert Garofalo, Aima A. Ahonkhai, Lisa R. Hirschhorn

“…These results are important for informing future work to scale-out iCARE and similar interventions to new settings. …”
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Fusion of EEG and EMG signals for detecting pre-movement intention of sitting and standing in healthy individuals and patients with spinal cord injury by Chenyang Li, Chenyang Li, Yuchen Xu, Tao Feng, Tao Feng, Minmin Wang, Minmin Wang, Minmin Wang, Xiaomei Zhang, Li Zhang, Li Zhang, Ruidong Cheng, Weihai Chen, Weihai Chen, Weidong Chen, Weidong Chen, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang, Shaomin Zhang

“…The final prediction was determined using a majority voting scheme.ResultsAmong the three functional connectivity methods investigated—coherence, Pearson correlation coefficient and mutual information (MI)—the MI-based EEG–EMG network showed the highest decoding performance (94.33%), outperforming both EEG (73.89%) and EMG (89.16%). …”
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Cord Direct Antiglobulin Test for Predicting the Need for Phototherapy in Neonates with ABO Incompatibility: A Prospective Cohort Study by Ranjith Balan, Sakthipriya Balaji, Arun Kumar, Subash Sundar, Shrinidhi Krishnan, Ashok Chandrasekaran

“…Following the acquisition of informed consent, cord blood samples were collected from 934 neonates delivered after 35 weeks of completed gestation to mothers with O blood type. …”
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Assessment of nurses’ knowledge and practice of pressure injuries prevention for critically ill patients in Rwanda: a cross-sectional study by Sophie Mukantwari, Emmanuel Bikorimana, Liberatha Rumagihwa, Ime U. Akaninyene, Christian Ntakirutimana, Joseph Mucumbitsi, Thierry Claudien Uhawenimana, David Ikwuka

“…In addition, barriers affecting nurses’ practices in this area also need further investigation in order to inform the interventions to improve nursing care of patients with pressure injuries in Rwandan hospitals. …”
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Geomorphic time series reveals the constructive and destructive history of Havre caldera volcano, Kermadec arc by E. Spain, R. J. Carey, J. M. Whittaker, V. L. Lucieer, J. M. Fox, J. M. Fox, J. M. Fox, S. J. Watson, F. Caratori Tontini

“…We also integrate the results of previous geological studies of Havre to inform the geomorphic interpretation. Our map reveals a variety of geomorphic forms from a range of volcanic and mass-wasting processes that aid in the interpretation of the growth and evolution of submarine volcanoes. …”
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Phenotypic diversity of CTCs and tdEVs in liquid biopsies of tumour-draining veins is linked to poor prognosis in colorectal cancer by Stefan A. Cieslik, Andrés G. Zafra, Christiane Driemel, Monica Sudarsanam, Jan-Philipp Cieslik, Georg Flügen, Levent Dizdar, Andreas Krieg, Sascha Vaghiri, Hany Ashmawy, Stephen Fung, Miriam Wilms, Leon W. M. M. Terstappen, Afroditi Nanou, Hans Neubauer, Nuh N. Rahbari, Wolfram T. Knoefel, Nikolas H. Stoecklein, Rui P. L. Neves

“…However, their low abundance in peripheral blood limits their informative value. In this study, we explored the presence of CTCs and tdEVs collected intraoperatively from a tumour-draining vein (DV) and via a central venous catheter (CVC) prior to tumour resection. …”
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Characteristics and long-term health outcomes of the first domestic COVID-19 outbreak cases in Da Nang, Vietnam: a longitudinal cohort study by Miyuki Tsuruoka, Mai Kim Huynh, Michiko Toizumi, Thanh Tien Hoang, Trieu Bao Nguyen, Anh The Dao, Luong Dinh Nguyen, Huy Xuan Le, Chung Thanh Le, Anh Quang Dang, Hung Thai Do, Lay Myint Yoshida

“…Clinical and demographic information was retrospectively collected from medical charts. …”
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Characteristics of base materials and acrylates used in removable prosthetics in dental practice (review) by Yu.I. Poliukhovych, A.Ye. Demkovych, Yu.I. Bondarenko, V.V. Shcherba, O.I. Lebid, K.M. Duda

“…After systematization of the selected information using general scientific methods, 70 most relevant sources remained. …”
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Patient Voices: Multimethod Study on the Feasibility of Implementing Electronic Patient-Reported Outcome Measures in a Comprehensive Cancer Center by Cinzia Brunelli, Sara Alfieri, Emanuela Zito, Marco Spelta, Laura Arba, Linda Lombi, Luana Caselli, Augusto Caraceni, Claudia Borreani, Anna Roli, Rosalba Miceli, Gabriele Tine', Ernesto Zecca, Marco Platania, Giuseppe Procopio, Nicola Nicolai, Luigi Battaglia, Laura Lozza, Morena Shkodra, Giacomo Massa, Daniele Loiacono, Giovanni Apolone

“…ConclusionsThis study provides useful information for future ePROM implementation strategies, aimed at effectively supporting the routine clinical management and care of patients with cancer. …”
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A Digital Tool for Clinical Evidence–Driven Guideline Development by Studying Properties of Trial Eligible and Ineligible Populations: Development and Usability Study by Shahzad Mumtaz, Megan McMinn, Christian Cole, Chuang Gao, Christopher Hall, Magalie Guignard-Duff, Huayi Huang, David A McAllister, Daniel R Morales, Emily Jefferson, Bruce Guthrie

“…Currently, the process is complex, onerous, and time-consuming, whereas a real-time tool may be used to rapidly inform a guideline developer’s judgment about the applicability of evidence. …”
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