Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled Trials by Vittorio Unfer, John E. Nestler, Zdravko A. Kamenov, Nikos Prapas, Fabio Facchinetti

“…It affects about 5–10% of women of reproductive age who typically suffer from obesity, hyperandrogenism, ovarian dysfunction, and menstrual irregularity. …”
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Clinical Profiles, Occurrence, and Management of Adolescent Patients with HAIR-AN Syndrome by Hatim A. Omar, Stephanie Logsdon, Jessica Richards

“…The syndrome of hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) is a subphenotype of the polycystic ovary syndrome. …”
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Obesity Differentially Affects Phenotypes of Polycystic Ovary Syndrome by Carlos Moran, Monica Arriaga, Gustavo Rodriguez, Segundo Moran

“…Phenotypes of PCOS have been described on the presence of clinical hyperandrogenism, oligoovulation and polycystic ovaries. …”
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Pathophysiologic Mechanisms of Insulin Secretion and Signaling-Related Genes in Etiology of Polycystic Ovary Syndrome by Zahra Shaaban, Arezoo Khoradmehr, Amir Amiri-Yekta, Fariborz Nowzari, Mohammad Reza Jafarzadeh Shirazi, Amin Tamadon

“…PCOS is characterized by anovulation, hyperandrogenism, polycystic ovaries, insulin resistance, and obesity. …”
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Proposal for an Educational Program for the Prevention of Complications of Polycystic Ovary Syndrome by Edison Sotalin Nivela, Lexter Michalache Bernal, María de Lourdes Llerena Cepeda

“…<strong>Foundation:</strong> polycystic ovary syndrome is characterized by hyperandrogenism and oligoovulation. It affects women of reproductive age and can have serious health implications. …”
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A Case of Successful Treatment with Unilateral Oophorectomy in a Patient with Resistant Polycystic Ovary Syndrome by S. Pathmanathan, I. Ranathunga, N. P. Somasundaram

“…Typical features consist of oligo/anovulation, polycystic ovaries, and features of hyperandrogenism. Pathogenesis is multifactorial, and positive family history may have a predisposition for disease development. …”
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Prevalence Of Skin Manifestations In Patients With Polycystic Ovarian Syndrome by Tehseen Naveed, Asma Afzal Kiyani, Sameena Kausar, Aqsa Naheed, Dawood Khan, Sakina Sadiq Malik

“…Keywords: PCOS, Skin manifestations, Hyperandrogenism, Hirsutism, Acne. …”
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A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women by Elena Benelli, Scilla Del Ghianda, Caterina Di Cosmo, Massimo Tonacchera

“…We evaluated the effects of a therapy that combines myo-inositol (MI) and D-chiro-inositol (DCI) in young overweight women affected by polycystic ovary syndrome (PCOS), characterized by oligo- or anovulation and hyperandrogenism, correlated to insulin resistance. Methods. …”
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Gestational diabetes mellitus and polycystic ovary syndrome, a position statement from EGOI-PCOS by Paola Quaresima, Samuel H. Myers, Basilio Pintaudi, Basilio Pintaudi, Rosario D’Anna, Rosario D’Anna, Michele Morelli, Vittorio Unfer, Vittorio Unfer

“…One of the major risk factors for the development of gestational diabetes mellitus is polycystic ovary syndrome, primarily due to the biochemical hyperandrogenism and metabolic issues, commonly observed in these patients. …”
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Update on the therapeutic role of metformin in the management of polycystic ovary syndrome: Effects on pathophysiologic process and fertility outcomes by Kerstin MG Brand, Ulrike Gottwald-Hostalek, Aimee Andag-Silva

“…PCOS is an insulin-resistant state, which drives hyperandrogenism and anovulatory infertility. The metabolic action of metformin involves amelioration of insulin resistance, which helps to resolve hormonal and metabolic disturbances and increases ovulation, pregnancy, and live birth rates relative to placebo. …”
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The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic-Cytoprotective Adjuvant Therapy by Eduardo Spinedi, Daniel P. Cardinali

“…Although its etiology is not fully understood, evidence suggests that insulin resistance, with or without compensatory hyperinsulinemia, and hyperandrogenism are very common features of the polycystic ovary syndrome phenotype. …”
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Ocular Surface Disease Severity in Polycystic Ovary Syndrome: is This Really Significant in Daily Life? by Demet Yabanoglu, Funda Gode

“…Polycystic ovary syndrome was diagnosed when two of the following conditions were met: oligo- or anovulation, clinical and/or biochemical signs of hyperandrogenism, and ultrasonographic documentation of polycystic ovaries. …”
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Adrenocortical Production Is Associated with Higher Levels of Luteinizing Hormone in Nonobese Women with Polycystic Ovary Syndrome by Luciana Tock, Gláucia Carneiro, Andrea Z. Pereira, Sérgio Tufik, Maria Teresa Zanella

“…Insulin resistance (IR) and ovarian and adrenal hyperandrogenism are a common finding in women with polycystic ovary syndrome (PCOS). …”
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Efficacy and Safety of Tracnil™ Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study by Ezhil Arasan Ramanan, Sailatha Ravi, K. R. Radha Anbu, Margaret Michael

“…Myo-inositol’s role in improving acne by reducing hyperandrogenism has been demonstrated in PCOS patients. …”
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Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential by Jingyi Yuan, Zhenmin Li, Yongjiang Yu, Xiuge Wang, Yunyun Zhao

“…Polycystic ovary syndrome (PCOS) is a multifaceted endocrine disorder characterized by irregularities in gonadotropin secretion, hyperandrogenism, chronic anovulation, and polycystic ovarian morphology. …”
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The Use of Yoga in the Treatment of PCOS by Agnieszka Przesor Przezor, Natalia Medźwiedzka

“…Symptoms include multiple ovarian cysts, hyperandrogenism (high levels of male hormones), and irregular menstrual cycles. …”
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Role of Lipotoxicity and Contribution of the Renin-Angiotensin System in the Development of Polycystic Ovary Syndrome by Alexandre Connolly, Samuel Leblanc, Jean-Patrice Baillargeon

“…Polycystic ovary syndrome (PCOS) is a common and significant condition associated with hyperandrogenism, infertility, low quality of life, and metabolic comorbidities. …”
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Bilateral Leydig Cell Hyperplasia: A Rare Cause of Postmenopausal Hirsutism by S. Pathmanathan, S. D. N. De Silva, M. Sumanatilleke, D. Lokuhetty, U. V. V. Ranathunga

“…Successful treatment of hyperandrogenism can result in improvement of glycaemic control. …”
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Impact of headache in women with polycystic ovary syndrome by Lina Zabulienë, V. Hendrixson, M. Urbonas, I. Ilias, D. Jatužis

“…Materials and methods. 114 women with PCOS (according to the Rotterdam criteria) and 80 age-matched control women with regular menses and no clinical or biochemical hyperandrogenism or polycystic ovaries were enrolled in the study. …”
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Action Mechanisms of Metformin Combined with Exenatide and Metformin Only in the Treatment of PCOS in Obese Patients by Jingwen Gan, Jie Chen, Rui-lin Ma, Yan Deng, Xue-song Ding, Shi-yang Zhu, Ai-jun Sun

“…Polycystic ovary syndrome (PCOS) is the most common endocrine disease in women of reproductive age, whose clinical characteristics are hyperandrogenism (HA), ovulatory dysfunction, and polycystic ovary, often accompanied by insulin resistance (IR) and metabolic abnormalities. …”
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