Implementing an intrahospital transport preparation (IHT) and management project for critically ill patients: identification of barriers and facilitators using consolidated framewo... by Jing Wang, Li Ma, Ying Lu, Baohua Li, Xiaotian Zhang, Rui Xie, Guifen Li, Man Cui, Lanfang Du

“…Facilitators were identified in four primary domains: ease of implementation, scientific and project completion, patient advantages and enhanced capacity for safe and professional transfer. Additionally, hurdles were identified in the CFIR domains of intervention characteristics, outer settings and inner settings. …”
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Extracellular vesicle surface engineering with integrins (ITGAL & ITGB2) to specifically target ICAM-1-expressing endothelial cells by Markus Bergqvist, Kyong-Su Park, Nasibeh Karimi, Lijuan Yu, Cecilia Lässer, Jan Lötvall

“…Abstract Extracellular vesicles (EVs) are taken up by most cells, however specific or preferential cell targeting remains a hurdle. This study aims to develop an EV that targets cells involved in inflammation, specifically those expressing intercellular adhesion molecule-1 (ICAM-1). …”
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Six-Phase Fully Coreless Axial-Flux Permanent-Magnet Generator: Design, Fabrication, and Performance Analysis by Turki M. Alsuwian, Asiful Habib, Muhammad Ammirrul Atiqi Mohd Zainuri, Ahmad Asrul Ibrahim, Nasrudin Abd Rahim, Adam R. H. Alhawari, Abdulkarem H. M. Almawgani, Saleh Almasabi, A. T. Hindi, Mohamed Fauzi Packeer Mohamed

“…Nevertheless, the proliferation of coreless AFPM machines faces hurdles as to high leakage flux and weaker structural integrity. …”
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Factors influencing livestock ownership and herd intensity among smallholder farmers in the Eastern Cape, South Africa by Jabulile Z. Manyike, Amon Taruvinga, Leocadia Zhou

“…Data were collected through a semi-structured questionnaire and analysed using a double hurdle model. The findings reveal that the decision to own livestock is positively influenced by adherence to African traditional religion, access to climate information, membership in farming organizations, income diversification, possession of formal housing, exposure to high average temperatures, and the likelihood of being in female-headed households. …”
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Leaflet: Operative Steps for Interventional Studies in Neuroscience by Maria Meringolo, Sergio Delle Monache, Giuseppina Martella, Antonella Peppe

“…Notably, neuroscience drug development encounters distinct challenges, including the complex nature of diseases, limitations imposed by the blood–brain barrier, the absence of reliable predictive preclinical models, and regulatory hurdles. Ethical and safety considerations are pivotal due to the potential cognitive and motor effects of CNS-active drugs. …”
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Design and implementation of an asynchronous online course-based undergraduate research experience (CURE) in computational genomics. by Seema B Plaisier, Danielle O Alarid, Joelle A Denning, Sara E Brownell, Kenneth H Buetow, Katelyn M Cooper, Melissa A Wilson

“…As genomics technologies advance, there is a growing demand for computational biologists trained for genomics analysis but instructors face significant hurdles in providing formal training in computer programming, statistics, and genomics to biology students. …”
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Reliability and Differences Between Sexes in Landing Mechanics when Performing the Lateral Bound Test by Andy Waldhelm, Sydney Allen, Lacy Grand, Carolyn Bopp, Kristian Foster, Ginger Muckridge, Neil Schwarz

“… # Materials/Methods Each subject performed three trials of a LBT which included jumping laterally from one leg over a hurdle and landing on the opposite leg. Two cameras were placed six feet from the landing marker. …”
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Repeatability and High-Speed Validation of Supplemental Lead-Extrusion Energy Dissipation Devices by Geoffrey W. Rodgers, J. Geoffrey Chase, John B. Mander

“…However, despite several research study tests and a limited range of velocity testing, they have never been tested across a realistic velocity range or for robustness to manufacture and design across several devices. These issues are hurdles that limit professional design uptake and add uncertainty and risk to their use in design. …”
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Genetic diversity and differentiation of cultured Nile tilapia populations from Ethiopia revealed by ddRAD-seq: implications for better hatchery management by Geletu Temesgen Tola, Tang Shoujie, Zhao Jinliang

“…Hence, the development of aquaculture in Ethiopia faces a major hurdle owing to the absence of good-quality seeds, largely because of the lack of genetic management practices within hatchery centers. …”
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The small modular molten salt reactor potential and opportunity in Saudi Arabia by Dana Hejazi, Anas M. Alwafi, Salman M. Alzahrani, Meshari M. Alqahtani, Salman M. Alshehri

“…While implementing MSRs requires overcoming technical hurdles, mainly related to structural materials withstanding extreme conditions, Saudi Arabia’s thriving research ecosystem is well-suited for overcoming such challenges. …”
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Treating self-harm behaviors in prisons: implementation of the STEPPS program by Rosa Lorente-Català, Irene Jaén, Xavier Buscà-Huertas, Berta Framis, Azucena García-Palacios

“…However, significant challenges arise when implementing evidence-based programs within this complex setting. Despite these hurdles, the Systems Training for Emotional Predictability and Problem Solving (STEPPS) program has garnered recognition, notably in the United States, for its efficacy in tackling such issues. …”
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RENEWABLES IN DEVELOPMENT OF THE ARAB EAST (CASE OF SOLAR ENERGY) by A. O. Filonik, V. A. Isaev, V. M. Morozov

“…Insufficient experience and lack of competence are followed by more serious factors seeing in bureaucratic hurdles, passivity of national capital, incorrect distribution of functions among administrative bodies, etc. …”
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What enabled the successful implementation of a quality certification initiative in Bhavnagar, Gujarat? A policy analysis case study. by K Shruti Lekha, Sudha Ramani, Harsha Joshi, Preet Verma, Sumit Malhotra, Tapasvi Puwar, Chandramani Kumar, Ankita Shah, Anish Sinha, Deepak Saxena

“…The district's mid-level operational team on quality has engaged with innovative solutions to solve checklist-related hurdles in infrastructure like establishing a temporary fire-escape or installing screens between rooms for additional space. …”
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Genebanks and market participation: evidence from groundnut farmers in Malawi by Martin Paul Jr. Tabe-Ojong, Melinda Smale, Nelissa Jamora, Vania Azevedo

“…Different econometric techniques were used, including a double hurdle model to understand market participation and quantity of groundnuts sold. …”
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A Review on Person Re-Identification Techniques and Its Analysis by C. Selvan, H. Anwar Basha, K. Meenakshi, Soumyalatha Naveen

“…It delves into three crucial facets; encompassing succinct explanations of video re-ID techniques along with their constraints, pivotal breakthroughs coupled with the technical hurdles faced, and the architectural framework underpinning these developments. …”
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Firth's penalized logistic regression: A superior approach for analysis of data from India's National Mental Health Survey, 2016 by Satish Suhas, Narayana Manjunatha, Channaveerachari Naveen Kumar, Vivek Benegal, Girish N. Rao, Mathew Varghese, Gopalkrishna Gururaj

“…In response to these data-driven hurdles, NMHS recognized the critical necessity for an alternative to conventional logistic regression, one that could adeptly navigate these complexities, ensuring robust and dependable insights from the collected data. …”
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Diagnosing skin neglected tropical diseases with the aid of digital health tools: A scoping review. by Ewelina Julia Barnowska, Anil Fastenau, Srilekha Penna, Ann-Kristin Bonkass, Sophie Stuetzle, Ricky Janssen

“…However, the results emphasized the existing lack of data regarding the diagnostic precision of these tools, and highlighted various hurdles to their effective implementation, including insufficient infrastructure, data security issues and low adherence to the routine use of digital health tools. …”
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Using Pretreatment of Carbon Monoxide Combined with Chlorine Dioxide and Lactic Acid to Maintain Quality of Vacuum-Packaged Fresh Beef by Fei Lyu, Yuliang Zhao, Kejing Shen, Xuxia Zhou, Jianyou Zhang, Yuting Ding

“…Due to microbial growth, beef easily gets corrupt in retail conditions, and the color and quality of the meat will be deteriorated. Therefore, hurdle technology, namely, pretreatment of carbon monoxide (CO), chlorine dioxide, and lactic acid, is used for vacuum-packaged beef to decontaminate beef and increase its quality stability. …”
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Single domain antibody-scFv conjugate targeting amyloid β and TfR penetrates the blood–brain barrier and interacts with amyloid β by Rebecca Faresjö, Elisabet O. Sjöström, Tiffany Dallas, Magnus M. Berglund, Jonas Eriksson, Dag Sehlin, Stina Syvänen

“…Immunotherapies, including the marketed antibodies lecanemab (Leqembi®) and donanemab (KisunlaTM), offer promise but face hurdles due to limited delivery across the blood–brain barrier (BBB). …”
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Isolation of a tumor neoantigen specific CD8+ TCR from a skin biopsy of a vaccination site by Maria Paula Roberti, Pornpimol Charoentong, Yanhong Lyu, Marten Meyer, Stefan B. Eichmüller, Patrick Schmidt, Frank Momburg, Miray Cetin, Felix Hartmann, Nektarios A. Valous, Albrecht Stenzinger, Laura Michel, Peter Lichter, Andreas Schneeweiss, Verena Thewes, Carlo Fremd, Inka Zörnig, Dirk Jäger

“…The easy and safe accessibility of skin biopsies overcomes the major hurdles of current TCR screening approaches and present exciting opportunities for the development of innovative immunotherapeutic strategies.…”
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