Reducing Nitrogen Waste: Factors Influencing Neem‐Coated Urea Adoption in Bhutan by Toritseju Begho, Tashi Dorji, Sonam Dendup

“…Analysing data from 235 farmers using a double hurdle regression model, the paper identified several positive drivers of NCU adoption, including multiple plots, larger farm size, organic fertiliser use, recent agricultural training, and seeking advice on fertiliser decisions. …”
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Transposon mediated functional genomic screening for BRAF inhibitor resistance reveals convergent Hippo and MAPK pathway activation events by Li Chen, Iulian Pruteanu-Malinici, Anahita Dastur, Xunqin Yin, Dennie Frederick, Ruslan I. Sadreyev, Cyril H. Benes

“…Abstract Genotype-informed anticancer therapies such as BRAF inhibitors can show remarkable clinical efficacy in BRAF-mutant melanoma; however, drug resistance poses a major hurdle to successful cancer treatment. Many resistance events to targeted therapies have been identified, suggesting a complex path to improve therapeutics. …”
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Integrating malaria vaccine and CRISPR/Cas9 gene drive: a comprehensive strategy for accelerated malaria eradication by Israel Charles Abraham, John Ehi Aboje, Bonaventure Michael Ukoaka, Kehinde Tom-Ayegunle, Maryam Amjad, Anas Abdulkader, Chinonyelum Emmanuel Agbo, Oluwatosin Ayokunle Akinruli, Taiwo Rebecca Akisanmi, Emmanuel Oyedeji Oyetola, Gbolahan Olatunji, Emmanuel Kokori, Nicholas Aderinto

“…Challenges such as regulatory hurdles, community acceptance, ecological impacts, and sustainable funding are examined, alongside strategies for implementation within existing malaria control programmes. …”
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A Process Model for the Implementation of Blockchain-Based Systems by Muhammad Nasim Bahar, Michal Ries, Kristian Kostal

“…This study tackles these hurdles by introducing a process model for the implementation of a blockchain-based system (PM-IBS), a comprehensive framework that guides organizations through the complexities of the adoption of blockchain systems. …”
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Fibroblasts in rheumatoid arthritis: novel roles in joint inflammation and beyond by Elpida Neofotistou-Themeli, Elpida Neofotistou-Themeli, Panagiota Goutakoli, Panagiota Goutakoli, Theodoros Chanis, Theodoros Chanis, Maria Semitekolou, Maria Semitekolou, Eirini Sevdali, Eirini Sevdali, Prodromos Sidiropoulos, Prodromos Sidiropoulos

“…Although our knowledge of ILD has progressed, significant gaps in both basic and clinical science remain, posing hurdles to efficient diagnosis, prediction of disease course and its effective treatment. …”
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Current Advance and Future Prospects of Tissue Engineering Approach to Dentin/Pulp Regenerative Therapy by Ting Gong, Boon Chin Heng, Edward Chin Man Lo, Chengfei Zhang

“…Nevertheless, many practical hurdles need to be overcome prior to its application in clinical settings. …”
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Impact of E-Learning, Perception and Attitude among Students and Faculty following the COVID-19 Pandemic by Syed Hamza Zia, Ghina Rizwan, Afifa Ehsan, Zarnab Rizwan, Rabia Masood, Naila Umer

“…Many efforts such as social distancing was made to cut down the spread of the virus in its early days and restrictions were followed by numerous countries worldwide which resulted in serious hurdles in all sectors of our daily lives such as education, financial and social activities. …”
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Brown Bear, Brown Bear, What Can You See? Exploring the Tension Between Strategic Choices and Claimants’ Voices in Environmental Litigation in the EU by Reilly Anne Dempsey Willis

“…There are many legal hurdles to bringing environmental claims and it is possible that the voice of the environment and those most adversely affected by its degradation is lost in the strategic legal decision-making. …”
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Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease by Jason P. Weick

“…While significant advances have been made, critical hurdles must be overcome in order for this technology to support progression toward clinical applications.…”
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Advancements in training and deployment strategies for AI-based intrusion detection systems in IoT: a systematic literature review by S. Kumar Reddy Mallidi, Rajeswara Rao Ramisetty

“…The study concludes by synthesizing the major challenges facing current IDS implementations in IoT and suggesting future research directions aimed at overcoming these hurdles. This review highlights the technological advancements in IDS and sets the stage for future enhancements in IoT security, emphasizing the integration of innovative training and deployment strategies.…”
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Essential Oils as Natural Food Preservatives: Special Emphasis on Antimicrobial and Antioxidant Activities by Nooshin Noshirvani

“…By using encapsulation, active packaging, hurdle technology, etc., the applied dose is reduced which can further reduce the negative effects of EOs on sensorial properties. …”
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An UAV-assisted VANET architecture for intelligent transportation system in smart cities by Ali Raza, Syed Hashim Raza Bukhari, Farhan Aadil, Zeshan Iqbal

“…The severity of these challenges become even more intensified when deployed in urban areas. To overcome these hurdles, integrating micro unmanned aerial vehicles with vehicular ad hoc network provides a viable solution. …”
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Missed, but Momentous: A Comprehensive Review of Neglected Tropical Skin Diseases in Southern India and their Global Impact by Ramesha M Bhat, N Swathi

“…This systematic review aims to probe into the intricate facets of NTDs in South India, delving into each dermatological NTD in detail, spotlighting their essence, prevalence, socio-economic reverberations, hurdles, and the necessity for collective action. …”
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The effect of smart contracts (blockchain technology) on Jordan’s land registry and survey department for sustainable development by AbdelKarim Fawwaz AlBataineh

“…Despite these promising results, the study acknowledges critical challenges such as the need for technical expertise, regulatory frameworks, and initial investment hurdles. Addressing these challenges is crucial for balanced implementation and sustained engagement with the technology. …”
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Synergies of Electric Vehicle Multi-Use: Analyzing the Implementation Effort for Use Case Combinations in Smart E-Mobility by Patrick Vollmuth, Maximilian Hampel

“…Challenges in the implementation of the combinations investigated arise primarily from technical hurdles and the fact that some use cases have not yet been fully defined in regulatory terms.…”
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The long road from urban experimentation to the transformation of urban planning practice: The case of tactical urbanism in the city of Barcelona by Franziska Schreiber

“…The study suggests that political pressure on planners to avoid failure, bureaucratic hurdles, and the lack of (process) learning are among the main barriers to generating valuable lessons for planning and institutionalizing innovations. …”
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Progress towards Sustainable Utilisation and Management of Food Wastes in the Global Economy by Purabi R. Ghosh, Derek Fawcett, Shashi B. Sharma, Gerrard Eddy Jai Poinern

“…Factors contributing to food waste, effective cost/benefit food waste utilisation methods, sustainability and environment considerations, and public acceptance are identified as hurdles in preventing large-scale food waste processing. …”
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Synthetic genomics in crop breeding: Evidence, opportunities and challenges by Yuhan Zhou, Ziqi Zhou, Qingyao Shu

“…Despite these advancements, the integration of synthetic genomics into crop breeding encounters hurdles, including the intricacies of complex crop genomes, the unpredictability introduced by epigenetic modification, and the limitations in achieving robust transformation processes. …”
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In-building direct wastewater heat recovery solutions for enhancing thermal efficiency in domestic hot water systems by Balan Mircea, Sandu Mihnea, Bode Florin

“…Retrofitting existing buildings poses significant hurdles due to space constraints and plumbing modifications, while maintenance is essential to prevent efficiency losses from fouling. …”
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Devanagari Character Recognition: A Comprehensive Literature Review by Sandhya Arora, Latesh Malik, Sonakshi Goyal, Debotosh Bhattacharjee, Mita Nasipuri, Ondrej Krejcar

“…The lack of large, diverse datasets for training and evaluation is a significant hurdle. This review highlights efforts to create annotated datasets and benchmarks, providing a comprehensive overview of HDCR methodologies, strengths, limitations, and future research directions. …”
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