Sustainable 3D printing of bone scaffolds using animal biowaste feedstocks by A. Dukle, M. Ravi Sankar

“…The study also addresses the challenges and future perspectives of biowaste-derived feedstocks for bone tissue engineering, including regulatory hurdles, biocompatibility, and scalability.…”
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Maize Market Chain Analysis and the Determinants of Market Participation in the Gamo and Gofa Zones of Southern Ethiopia by Duge Galtsa, Kassa Tarekegn, Kusse Kamaylo, Endrias Oyka

“…The data were analyzed by using descriptive statistics, marketing margins, and the double hurdle model. The survey results revealed that approximately 35.88% of the maize from the total maize produced by the sampled farmers was marketed in the study area. …”
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Forced to Reimagine: Reflections on the Experience of Leicester Vaughan College Community Benefit Society by Miriam Gill, Lucy Faire

“…As we searched (and continue to search) for a ‘happy ending’ with LVC, the multiple hurdles experienced exemplify the difficulties of trying to create a space for a new paradigm within hostile, shifting structures shaped by neoliberal regulatory and economic imperatives. …”
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Inherent stochasticity, noise and limits of detection in continuous and time-gated fluorescence systems. by Nicholas H Vitale, Arjang Hassibi, Hyongsok Tom Soh, Boris Murmann, Thomas H Lee

“…While CW systems remain a gold standard, TG systems can be leveraged to overcome cost and system complexity hurdles when paired with the appropriate fluorophore.…”
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ETHNIC POLITICS AND SUSTAINABLE DEMOCRACY IN NIGERIA by UKWU FELIX EMEKA

“…The research contends that the endemic nature of ethnic politics presents significant hurdles to democracy's survival in Nigeria. The findings reveal various symptoms and ramifications of ethnic politics that hinder the consolidation of democracy, including heightened calls for self-determination, escalating insecurity, and stalled development. …”
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Immediate shock and residual stress: Unmasking the dual dynamics of covid-19 on the mental health of health professionals in China by Suyi Duan

“…It has posed extraordinary hurdles for Chinese health workers, affecting their mental health with respect to situations in the present as well as the future. …”
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Usage of Probabilistic and General Regression Neural Network for Early Detection and Prevention of Oral Cancer by Neha Sharma, Hari Om

“…It is critical to ascertain the diagnosis in order to initiate most advantageous treatment of the suspicious lesions. The main hurdle in appropriate treatment and control of oral cancer is identification and risk assessment of early disease in the community in a cost-effective fashion. …”
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QeMFi: A Multifidelity Dataset of Quantum Chemical Properties of Diverse Molecules by Vivin Vinod, Peter Zaspel

“…Much research is progressing in this direction for diverse applications ranging from energy band gaps to excitation energies. One hurdle for effective research here is the lack of a diverse multifidelity dataset for benchmarking. …”
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Current Trends in Targeted Therapies for Glioblastoma Multiforme by Fumiharu Ohka, Atsushi Natsume, Toshihiko Wakabayashi

“…In this paper, we review up-to-date clinical trials of GBM treatments in order to overcome these 4 hurdles and to aim at more therapeutical effect than conventional therapies that are ongoing or are about to launch in clinical settings and discuss future perspectives.…”
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Oligonucleotides as a Novel Therapeutic Approach: An Innovative Area for Drug Delivery in Neurological Disorders by Yasir Qasim Almajidi, Rana Kadum Muslim, Yaseen T. khalf

“…However, the delivery of nucleic acids to the central nervous system (CNS) by the systemic route, remains a major hurdle. To overcome this pitfall, this review focuses on oligonucleotide-based novel strategies including liposomes, carbon nanotubes, quantum dots, solid lipid nanoparticles, nano lipid carriers, polymeric nanoparticles, mesoporous silica, dendrimers, aptamers, nanobodies etc. …”
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Comparison of Flow Solutions for Naturally Fractured Reservoirs Using Complex Analysis Methods (CAM) and Embedded Discrete Fracture Models (EDFM): Fundamental Design Differences an... by Aaditya Khanal, Ruud Weijermars

“…One aim is to define scaling rules for the strength (flux) of the discrete natural fractures used in CAM models, which was previously theoretically defined based on the expected flow distortion. A major hurdle for quantitative benchmarks of CAM with EDFM results is that each of the two methods accounts for natural fractures with different assumptions and input parameters. …”
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UV-C and Nanomaterial-Based Approaches for Sulfite-Free Wine Preservation: Effects on Polyphenol Profile and Microbiological Quality by Kamila Pachnowska, Jolanta Kochel-Karakulska, Adrian Augustyniak, Valentina Obradović, Ireneusz Ochmian, Sabina Lachowicz-Wiśniewska, Ireneusz Kapusta, Klaudia Maślana, Ewa Mijowska, Krzysztof Cendrowski

“…These results open up discussion on the possible use of the proposed hurdle technology in winemaking to control the polyphenol composition and alcohol reduction.…”
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Challenges in the Diagnosis and Management of Growth Hormone Deficiency in India by Mathew John, Ekaterina Koledova, Kanakatte Mylariah Prasanna Kumar, Harshal Chaudhari

“…The diagnosis and treatment of GHD are hurdled with various challenges, restricting the availability of growth hormone (GH) therapy to only a very limited segment of the children in India. …”
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Current Status of Comprehensive Chromosome Screening for Elective Single-Embryo Transfer by Ming-Yih Wu, Kuang-Han Chao, Chin-Der Chen, Li-Jung Chang, Shee-Uan Chen, Yu-Shih Yang

“…However, unsatisfactory results in IVF may result from plenty of factors, in which aneuploidy associated with advanced maternal age is a major hurdle. Throughout the past few years, we have got a big leap in advancement of the genetic screening of embryos on aneuploidy, translocation, or mutations. …”
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Volatile Organic Metabolites as Potential Biomarkers for Genitourinary Cancers: Review of the Applications and Detection Methods by Kiana L. Holbrook, Wen-Yee Lee

“…However, developing robust VOC detection methods remains a hurdle. This review outlines the current landscape of major genitourinary cancers (kidney, prostate, bladder, and testicular), including epidemiology, risk factors, and current diagnostic tools. …”
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Correlation Analysis of Sprint Performance and Reaction Time Based on Double Logarithm Model by Jing Zhang, Xin-Yu Lin, Su Zhang

“…This study examines the reaction time and the results of the male and female sprinters participating in the World Athletics Championships from 2011 to 2019 in the 100 m, 200 m, 100 m, and 110 m hurdles. The researchers used least squares estimation, multivariate analysis of variance, and other methods and theories to construct a double logarithmic model and a multivariate analysis of a variance model. …”
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AutomationML Meets Bayesian Networks: A Comprehensive Safety-Security Risk Assessment in Industrial Control Systems by Pushparaj Bhosale, Wolfgang Kastner, Thilo Sauter

“…Acquiring data from various sources poses a significant hurdle. To address these challenges, automation markup language (AML) provides a standardized framework that facilitates the seamless exchange of engineering information. …”
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Direct Reprogramming of Mouse Fibroblasts to Neural Stem Cells by Small Molecules by Yan-Chuang Han, Yoon Lim, Michael D. Duffieldl, Hua Li, Jia Liu, Nimshitha Pavathuparambil Abdul Manaph, Miao Yang, Damien J. Keating, Xin-Fu Zhou

“…Although it is possible to generate neural stem cells (NSC) from somatic cells by reprogramming technologies with transcription factors, clinical utilization of patient-specific NSC for the treatment of human diseases remains elusive. The risk hurdles are associated with viral transduction vectors induced mutagenesis, tumor formation from undifferentiated stem cells, and transcription factors-induced genomic instability. …”
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Developing glycoproteomics reveals the role of posttranslational glycosylation in the physiological and pathological processes of male reproduction by Qingyuan Cheng, Mengqi Luo, Zihe Xu, Fuping Li, Yong Zhang

“…However, our grasp on glycosylation within male reproductive processes remains limited, largely due to the technical hurdles. Recent advancements have seen the mapping of the glycoproteome of human semen, utilizing cutting‐edge glycoproteomic technologies. …”
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Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review by Manjusha Bhange, Darshan Telange

“…However, data privacy, regulatory hurdles, and the need for large-scale clinical validation remain. …”
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