Assessing the Effectiveness of International Climate Agreements in Mitigating Global Warming by Anna Mravcová

“…The paper also discusses the challenges and obstacles in the process of implementing the agreements, such as compliance difficulties, political hurdles, and the involvement of various stakeholders. …”
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The Growth of Electronic-cigarette Use Globally and Its Implications for Australia – A Literature Review by Joul Kassis

“…Despite the current legal hurdles, Australian smokers have increased their usage of e-cigarettes during the last 10 years. …”
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Achieving myoblast engraftment into intact skeletal muscle via extracellular matrix by Kitora Dohi, Yasuko Manabe, Nobuharu L. Fujii, Yasuro Furuichi

“…Additionally, skeletal muscle-specific somatic stem cells, called satellite cells, lose their ability to adhere to tissue after being cultured in vitro and transforming into myoblasts. To overcome these hurdles, we explored using extracellular matrix (ECM) components to create a niche environment conducive for myoblasts during transplantation. …”
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Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges by Vidhi Mathur, Prachi Agarwal, Meghana Kasturi, Varadharajan Srinivasan, Raviraja N Seetharam, Kirthanashri S Vasanthan

“…By highlighting both the technological potential and regulatory hurdles, this review offers a comprehensive overview of the future landscape of bioinks in bioprinting, emphasizing the necessity for cross-disciplinary collaboration between scientists, clinicians, and regulatory bodies to achieve successful clinical applications.…”
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The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo by Carlo Galli, Giuseppe Pedrazzi, Monica Mattioli-Belmonte, Stefano Guizzardi

“…A broad range of settings used for PEMFs stimulation still represents a hurdle to better define treatment protocols and extensive research is needed to overcome this issue. …”
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Application of Sequence-Dependent Electrophoresis Fingerprinting in Exploring Biodiversity and Population Dynamics of Human Intestinal Microbiota: What Can Be Revealed? by Geert Huys, Tom Vanhoutte, Peter Vandamme

“…The first part of this review covers the methodological concept of SDE fingerprinting and the technical hurdles for analyzing intestinal samples. Subsequently, the current state-of-the-art of DGGE and related techniques to analyze human intestinal microbiota from healthy individuals and from patients with intestinal disorders is surveyed. …”
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Economic sustainability and community support by ex-migrants in rural communities in Lombok Tengah, Nusa Tenggara Barat by Sandiatmo Suyanto, Priyadi Budi Puspo, Falah Fajrul, Purwanti Tari, Putri Carolina Retmawati

“…The findings highlight the critical role of community support and the need for government intervention in encouraging these entrepreneurial activities. Despite the hurdles of minimal capital and limited land, these entrepreneurs contribute significantly to local economic development, particularly through small-scale enterprises such as brick molding, gardening, and poultry farming. …”
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A Critical Review of the Hydrometallurgy and Pyrometallurgical Recovery Processes of Platinum Group Metals from End-of-Life Fuel Cells by Sinikiwe A. Mvokwe, Opeoluwa O. Oyedeji, Mojeed A. Agoro, Edson L. Meyer, Nicholas Rono

“…The health risks, benefits, and limitations of these processes are highlighted. Finally, the hurdles faced by, opportunities for, and future directions of these approaches are identified. …”
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Roles of nanotechnology in electrochemical sensors for medical diagnostic purposes: A review by Ali R. Jalalvand, Mohammad Mehdi Karami

“…Despite the promising benefits, several challenges including technical, regulatory, and market barriers are discussed alongside potential strategies to overcome these hurdles. The ongoing research and development in this field promise to revolutionize medical diagnostics by providing rapid, accurate, and accessible testing solutions ultimately improving patient outcomes and healthcare efficiency.…”
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Large‐Vessel Occlusion Stroke Knowledge and Training for Stroke Severity Assessment Among Emergency Medical Services Personnel in the United States by Kaiz S. Asif, Robin Novakovic, Thanh N. Nguyen, Santiago Ortega‐Gutierrez, Youngran Kim, Amanda Jagolino‐Cole, Sushanth Aroor, Alicia Castonguay, Prateek Kumar, Ashutosh P. Jhadav, Dileep Yavagal, May Nour, Gabor Toth, Maxim Mokin, Sunil A. Sheth, Mouhammad A. Jumaa, Alhamza Al‐bayati, Mohamed Teleb, Ossama Y. Mansour, Shashvat M. Desai, Joshua Hartman, David S. Liebeskind, Ameer E. Hassan, Brijesh P. Mehta

“…It included 12 multiple‐choice and free‐response questions designed to test participants’ clinical knowledge of LVO, knowledge of stroke center certification levels, prior LVO educational experiences, preferences for educational content delivery, and perspectives on prehospital hurdles to stroke care. All subscribers of EMS World received a survey link via email. …”
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The Essentials of Clinical Trial Management: Addressing Needs for Successful Outcomes by Gunjan Kumar, Aparna Mukherjee

“…Finally, it examines the complexities of multi-centric clinical trials, offering strategies for overcoming these hurdles.…”
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PROTAC technology for prostate cancer treatment by Zhen Wang, Dingpeng Zhang, Hiroyuki Inuzuka, Wenyi Wei

“…Although androgen deprivation therapy remains the mainstay for early-stage PrCa treatment, efficacy is temporary because many cases advance to castration-resistant PrCa (CRPC), presenting a significant therapeutic hurdle. This review explores key biomarkers for PrCa and the latest therapeutic strategies for CRPC with a particular focus on the innovative proteolysis-targeting chimera (PROTAC) technology. …”
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Climate effects on the diversification strategy of export firms: Evidence from China. by Junmei Zhang, Lianying Yao

“…The results of the study show that as climate change intensifies, leading to more frequent extreme temperatures, firms will face significant hurdles in pursuing diversified development strategies, pointing to increasing challenges ahead.…”
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An exact approach to calibrating infectious disease models to surveillance data: The case of HIV and HSV-2 by David J. Gerberry

“…While frequently overlooked, the calibration process is nontrivial at best and can be inefficient, poorly communicated and a major hurdle to the overall reproducibility of modeling results.In this work, we describe a general approach to calibrating infectious disease models to surveillance data. …”
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Total shoulder arthroplasty in a patient with osteopetrosis: A case report by Ryan C. Rizk, MS, Elias Lugo-Fagundo, BS, Mohammad Yasrab, MD, Edmund M Weisberg, MS, MBE, Linda C. Chu, MD, John M. Gross, MD, Elliot K. Fishman, MD

“…When osteoarthritis results in significant pain and impairs function, surgical interventions such as total joint arthroplasty may be recommended, although these procedures come with a unique set of surgical and recovery-related hurdles. Due to its challenging preoperative diagnosis, radiological imaging plays a fundamental role in the detection of osteopetrosis, along with the evaluation of the extent of disease. …”
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Natural Training in Control of Formal Education: A Critical Analysis ofthe Book " Zaynab Letters" by seyyed hosyn hoseyni

“…The difference between formal education and education training, based on the human and divine nature of the individual mechanisms, has always been one of the most important issues in the field of philosophy of education and has been considered the analysis of educational characteristics education.The main objective of this paper is to analyze the book "Zaynab Letters" through which the dimensions of these differences are explored; a general conceptual framework regarding prominent challenges in the formal education system and conceptual hurdles posed by the events in this book are discussed. .The paper aims to find out what  the principles and characteristics of children's innate language are. …”
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Pathways to Progress: Unveiling Structural Change in Africa Through Economic Transformation, Technology, Talent, and Tourism by Hugo Pinto, Evans Odoi, Carla Nogueira, Luiz Fernando Câmara Viana

“…Driven by urbanization, technological innovation, and global trade, this shift offers opportunities for sustainable growth but faces challenges such as infrastructure gaps and institutional hurdles. This paper examines the dynamics of structural change in 54 African countries, focusing on the roles of technology, talent, and tourism. …”
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Smart learning and the law: examining the case of the Dubai Judicial Institute and its inevitable transition towards a modern pedagogical paradigm by Hind Al-Mazmi, Khadeegha Alzouebi, Tendai Charles

“…However, the DJI faces specific challenges in transitioning to a smart learning model, including the potential loss of valuable personal interaction, significant financial and technological requirements, and the need for staff training to adapt to new systems. Despite these hurdles, both management and learners at the DJI express readiness and enthusiasm for this paradigm shift, driven by the benefits of flexibility, time efficiency, and increased learner autonomy. …”
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Fed-CL- an atrial fibrillation prediction system using ECG signals employing federated learning mechanism by Fayez Saud Alreshidi, Mohammad Alsaffar, Rajeswari Chengoden, Naif Khalaf Alshammari

“…Abstract Deep learning has shown great promise in predicting Atrial Fibrillation using ECG signals and other vital signs. However, a major hurdle lies in the privacy concerns surrounding these datasets, which often contain sensitive patient information. …”
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Advancing UAV Communications: A Comprehensive Survey of Cutting-Edge Machine Learning Techniques by Chenrui Sun, Gianluca Fontanesi, Berk Canberk, Amirhossein Mohajerzadeh, Symeon Chatzinotas, David Grace, Hamed Ahmadi

“…UAV have demonstrated considerable potential in addressing the evolving challenges of next-generation mobile networks, such as enhancing coverage and facilitating temporary hotspots but pose new hurdles including optimal positioning, trajectory optimization, and energy efficiency. …”
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