A mixed-method investigation of the root causes of construction project delays in Afghanistan by Mohammad Basheer Ahmadzai, Kunhui Ye

“…The research findings highlight the significant impact of security challenges, corruption, and logistical hurdles on construction project delays in Afghanistan. …”
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Advances in liver engineering with cell, scaffold, and vascularization by Chunyan Liu, Yulian Wang, Xuqian Zhou, Lei Dong

“…Further research is required to overcome these hurdles and ultimately realize the full potential of tissue-engineered liver constructs in clinical applications.…”
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Challenges of reproducible AI in biomedical data science by Henry Han

“…While adherence to reproducibility standards is essential for the long-term advancement of AI, the conflict between following these standards and aligning with researchers’ personal goals remains a significant hurdle in achieving AI reproducibility.…”
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Traffic incident and disaster management in the Netherlands by John Steenbruggen, Peter Nijkamp, Jan M. Smits, Ghaitrie Mohabir

“…Information, communication and coordination tasks, and especially problems in information quality, are identified as the main hurdles. This paper addresses, from a broad perspective, the relation and challenges between the two related fields.…”
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Item-level and Composite-level Interrater Reliability of Functional Movement Screen™ Scores Following Condensed Training in Novice Raters by Brent A Harper, Stephen M Glass

“…Reliability (kappa) was fair for Inline Lunge (0.24 Day 1, 0.39 Day 2), and poor for Hurdle Step (Day 1 -0.01, Day 2 no result) and Rotary Stability (Day 1 -0.03, Day 2 -0.01). …”
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Liver Xenotransplantation: A Path to Clinical Reality by Serkan Sucu, Serkan Sucu, Yucel Yankol, Luis A. Fernandez, Burcin Ekser

“…Understanding the mechanism behind those challenges and using novel genetically engineered pigs enabled researchers to overcome some of the hurdles, but more research is needed. However, new advances might allow pig liver xenotransplantation to potentially serve as a bridge to liver allotransplantation or allow native liver regeneration in the near future.…”
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Genome sequence of Vibrio sp. OULL4 isolated from shellfish by Vengadesh Letchumanan, Wen-Si Tan, Wai-Fong Yin, Kok-Gan Chan

“…The control of these vibrios has been a hurdle due to the rising numbers of antibiotic resistant strains in the environments. …”
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Improving CD3 bispecific antibody therapy in solid tumors using combination strategies by Katy Lloyd, Jim Middelburg, Vitalijs Ovcinnikovs, Nora Pencheva, Kristel Kemper, Thorbald van Hall

“…Despite these recent advances, the success of CD3 bsAbs in solid cancer has been hampered by hurdles like limited intratumoral T cell numbers, immunosuppressive tumor microenvironments (TME), and poor memory T-cell induction. …”
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Public Accountability and its Diverse Context: a Tale from Different Disciplinary Parameters. by Basheka, Benon

“…One of the greatest hurdles of sound administrative and governance contexts in Africa remains that of accountability. …”
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Insights into Viral Zoonotic Diseases: COVID-19 and Monkeypox by Alysha Kaur Sachdev, Vengadesh Letchumanan

“…The onset of the COVID-19 pandemic in 2019 and the sporadic occurrences of monkeypox virus infections have presented substantial hurdles to global healthcare. The appearance of these viruses underscores the persistent menace of infectious diseases. …”
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Artificial intelligence techniques applications in the wastewater: A comprehensive review by Zakur Yahya, Márquez Fausto, Al-Taie Ali, Alsaidi Saif, Alsadoon Abeer, Mirashrafi Seyed Bagher, Flaih Laith, Zakoor Yousif

“…There are some challenges are firms the wastewater treatment, numerous hurdles concerning the enhancement of the energy efficiency, compliance with the increasingly stringent water quality regulations, and the maximizing resource recovery opportunities. …”
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Prospect of Induced Pluripotent Stem Cell Genetic Repair to Cure Genetic Diseases by Jeanne Adiwinata Pawitan

“…In addition, the challenges in using the iPSC and the strategies to manage the hurdles are addressed.…”
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Distinct Functions of Specialized Dendritic Cell Subsets in Atherosclerosis and the Road Ahead by Alma Zernecke

“…Furthermore, an outlook on future challenges faced when studying DCs in this detrimental disease are provided, and hurdles that will need to be overcome in order to enable a better understanding of the contribution of DCs to atherogenesis are discussed, a prerequisite for their therapeutic targeting in atherosclerosis.…”
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Genome Editing as a Vehicle to Drive Successful Chimeric Antigen Receptor T Cell Therapies to the Clinic by Caitlin R Hopkins, Joseph A Fraietta

“…However, there are many challenges preventing clinical efficacy and thus broader translation of this approach. These hurdles include poor autologous T cell fitness, manufacturing issues and lack of conserved tumour-restricted antigens to target. …”
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Improving the reproducibility in geoscientific papers: lessons learned from a Hackathon in climate science by Alejandro Coca-Castro, Anne Fouilloux, Ricardo Barros Lourenço, Andrew McDonald, Yuhan Rao, J. Scott Hosking

“…The competition aimed at (1) identifying common hurdles to reproduce computational climate science; and (2) creating interactive reproducible publications for selected papers of the Environmental Data Science journal. …”
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Storing Digital Information in Long-Read DNA by TaeJin Ahn, Hamin Ban, Hyunsoo Park

“…Previous studies tackled technical hurdles due to errors from DNA synthesis and sequencing. …”
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Embracing Generative Artificial Intelligence in Clinical Research and Beyond by Henry P. Foote, MD, Chuan Hong, PhD, Mohd Anwar, PhD, Maria Borentain, MD, Kevin Bugin, PhD, Nancy Dreyer, PhD, MPH, Josh Fessel, MD, PhD, Nitender Goyal, MD, Morgan Hanger, MPP, Adrian F. Hernandez, MD, Christoph P. Hornik, MD, PhD, MPH, Jennifer G. Jackman, PhD, MBA, Alistair C. Lindsay, MD, MPH, DPhil, Michael E. Matheny, MD, Kerem Ozer, MD, Jan Seidel, PhD, Norman Stockbridge, MD, PhD, Peter J. Embi, MD, Christopher J. Lindsell, PhD

“…Challenges include technical hurdles, ethical dilemmas, and regulatory uncertainties. …”
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Recent Advances in Peptide-Loaded PLGA Nanocarriers for Drug Delivery and Regenerative Medicine by Hossein Omidian, Renae L. Wilson, Ana M. Castejon

“…Despite remarkable progress, challenges such as production scalability, cost, and regulatory hurdles remain.…”
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Unlocking the Potential of Chest MRI: Strategies for Establishing a Successful Practice by Kyubin Kim, Kun-Il Kim, Ji Won Lee, Yeon Joo Jeong

“…Despite the technical hurdles posed by cardiac and respiratory motion, advancements in sequence and scan techniques have enabled high-quality chest MRI examinations to be conducted across diverse clinical settings. …”
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Cybersecurity Infrastructure Compliance Key Factors to Detect and Mitigate Malware Attacks in SMEs: A Systematic Literature Review by Adnan Bin Amanat Ali, Ramesh Kumar Ayyasamy, Rehan Akbar, Abdulkarim Kanaan Jebna, Kiran Adnan

“…As the backbone of a nation’s economy, SMEs face challenges due to limited knowledge, awareness, and resource constraints. These hurdles hinder their adoption of existing frameworks and policies. …”
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