ZBP1-mediated PANoptosis is a crucial lethal form in diverse keratinocyte death modalities in UVB-induced skin injury by Xuechan Bi, Min Li, Yiming Guo, Mengyao Hu, Yujie Chen, Ni Lian, Sihan Chen, Min Li, Heng Gu, Xu Chen

“…We observed that the key molecules of GSDMD-mediated pyroptosis, apoptosis, and necroptosis, which are N-terminal GSDMD, cleaved caspase-3/PARP, and phosphorylated MLKL, respectively, were elevated in keratinocytes of UVB-challenged mice and human skin tissue. Through keratinocyte-specific gene knockout or using corresponding inhibitors, we found that individual inhibition of GSDMD-mediated pyroptosis, caspase-3-mediated apoptosis, or MLKL-mediated necroptosis did not reduce the overall level of keratinocyte death after UVB exposure, and that the other two pathways maintained the activation. …”
Get full text

Evaluation of the Microbiota and Integrity of Respirators Reused by Health Professionals in a Hospital Environment by José D. Paiva, Giselda Neves, Paulo C. Neto, Wanuska Portugal, Douglas Ferreira, Fernando Lundgren, Idalina Cambuim, Ana C. Paiva, Elvis França

“…The results obtained showed that the microbiota of the respirators comprised commensal fungi and bacteria from the oral and nasal regions of human beings. It was also found that after 36 h of use, the respirators did not demonstrate a decrease in filtration efficiency; that is, they retained their 97% filtration efficiency. …”
Get full text

Establishment of Novel Limbus-Derived, Highly Proliferative ABCG2+/ABCB5+ Limbal Epithelial Stem Cell Cultures by Eung Kweon Kim, Ga-Hyun Lee, Boram Lee, Yong-Sun Maeng

“…In this study, we identified the culture conditions required to expand LESCs in vitro and established human limbus-derived highly proliferative ABCG2+/ABCB5+ double-positive LESCs. …”
Get full text

Document-Level Neural TTS Using Curriculum Learning and Attention Masking by Sung-Woong Hwang, Joon-Hyuk Chang

“…Speech synthesis has been developed to the level of natural human-level speech synthesized through an attention-based end-to-end text-to-speech synthesis (TTS) model. …”
Get full text

Sequential transcriptome profiling: comparative analysis of normal and canine lymphoma preceding detailed T-cell and B-cell subtype comparison by Yeji Kim, Yeji Kim, Jihyun Kim, Jihyun Kim, Yunji Song, Yunji Song, Keunhwan Jang, Se Eun Kim, Se Eun Kim, Se Eun Kim, Ha-Jung Kim, Ha-Jung Kim

“…Additionally, genes with potential relevance to the clinical characteristics of T-cell lymphoma (TCL), which is characterized by a low treatment response and poor prognosis, were identified through a comparative analysis of different lymphoma subtypes.ResultsWithin the canine lymphoma group, HERC5 showed consistent upregulation, a gene similarly implicated in human acute myeloid leukemia but previously no reports exist. …”
Get full text

Leches a base de plantas: Nuez de marañón (anacardo) by Jamie Zeldman, Daniela Rivero-Mendoza, Wendy J. Dahl

“…Dahl, translated by Daniela Rivero-Mendoza, and published by the UF/IFAS Food Science and Human Nutrition Department. https://edis.ifas.ufl.edu/fs418 …”
Get full text

In Search of an Integrative Method to Study Unconscious Processing: An Application of Bayesian and General Recognition Theory Models to the Processing of Hierarchical Patterns in t... by Antonio Prieto, Pedro R. Montoro, Mikel Jimenez, José Antonio Hinojosa

“…The dissociation between conscious and unconscious perception is one of the most relevant issues in the study of human cognition. While there is evidence suggesting that some stimuli might be unconsciously processed up to its meaning (e.g., high-level stimulus processing), some authors claim that most results on the processing of subliminal stimuli can be explained by a mixture of methodological artefacts and questionable assumptions about what can be considered non-conscious. …”
Get full text

COVID-19 preguntas frecuentes para servicios de comida: preguntas generales y salud de los empleados by Natalie Seymour, Mary Yavelak, Candice Christian, Ben Chapman, Michelle Danyluk

“…Written by Natalie Seymour, Mary Yavelak, Candice Christian, and Ben Chapman (NC State University Extension), and published by the UF/IFAS Food Science and Human Nutrition Department, April 2020. FSHN20-16s/FS359: COVID-19 preguntas frecuentes para servicios de comida: preguntas generales y salud de los empleados (ufl.edu) …”
Get full text

Unveiling the antiglioblastoma potential of harmicens, harmine and ferrocene hybrids by Poje Goran, Šakić Davor, Marinović Marina, You Jiangyang, Tarpley Michael, Williams Kevin P., Golub Nikolina, Dernovšek Jaka, Tomašič Tihomir, Bešić Erim, Rajić Zrinka

“…., the C-6 substituted harmicene (IC50 = 7.4 ± 0.5 µmol L–1, SI = 5.8) exert remarkable activity and selectivity against human malignant glioblastoma cell line (U251) in vitro. …”
Get full text

Administrative and legal principles of formation of tariffs for freight transportation by railway transport by Voroniatnikov O.

“…The results of the research can be used in legislation and law-enforcement activities during the inquiry of crimes related to human trafficking and corruption.…”
Get full text

Profil Kesiapan dan Pemahaman Guru Biologi terhadap Pelaksanaan Asesmen Psikomotorik dan Afektif Selama Pembelajaran Online di SMA Seluruh Kecamatan Comal, Pemalang by Eka Nunik Suharjanti, Ipah Budi Minarti, Lussana Rossita Dewi

“…An understanding profile that has an impact on misconceptions in the realm of assessment and the development of an assessment rubric that is not yet good so that human application cannot run optimally. In addition, the application of psychomotor and affective assessments during online learning is influenced by the factors of the teacher's IT ability and the facilities owned by the students.…”
Get full text

First Case Report of a Late Onset Knee Periprosthetic Joint Infection Caused by Lactococcus garvieae by V.-I. Neagoe, S. Zytoun, H.-J. Neuhaus

“…The association between Lactococcus spp. and human infectious diseases is described as being mainly associated with lumbar osteomyelitis, hepatic abscess, and infective endocarditis. …”
Get full text

Severe Wound Infection with Photobacterium damselae ssp. damselae and Vibrio harveyi, following a Laceration Injury in Marine Environment: A Case Report and Review of the Literatur... by Jörg Hundenborn, Steffi Thurig, Mechthild Kommerell, Heike Haag, Oliver Nolte

“…Furthermore, the wound was coinfected with Vibrio harveyi, a halophile bacterium, which has never been reported from human infections before. Identification was achieved by use of Matrix-Assisted Laser Desorption-Ionization Time of Flight Mass Spectrometry (MALDI-TOF) and confirmed by 16S rDNA sequencing. …”
Get full text

The influence of emotional states induced by emotion-related auditory stimulus on ankle proprioception performance in healthy individuals by Keqing Yuan, János Négyesi, Takeshi Okuyama, Ryoichi Nagatomi

“…Abstract Human movement is influenced by emotions, yet their effect on proprioceptive behavior remains unclear. …”
Get full text

Treated Follicular Lymphoma, Recurrent Invasive Pneumococcal Disease, Nonresponsiveness to Vaccination, and a Unique Pneumococcus by Clare Murphy, Donald Inverarity, Claire McGoldrick, Lindsay Mitchell, Pamela Paterson, Louise Thom, Giles Edwards

“…Indirect immunofluorescence with anti-human immunoglobulin confirmed a poor or intermediate response to Pneumovax II. …”
Get full text

Adjuntive nicergoline therapy for severe persistent corneal epithelial defects. by Valeria Oliva-Biénzobas, Enrique O. Graue-Hernandez, Guillermo Raul Vera-Duarte, Jesus Cabral-Macías, Juan Serna-Ojeda, Victor Boullosa, Arturo Ramirez-Miranda, Vishal Jhanji, Victor L. Perez, Alejandro Navas

“…Further studies and clinical trials must be conducted to prove safety and efficacy as a treatment for persistent corneal epithelium defects in humans.…”
Get full text

Fiber-tip photonic crystal for real-time referenced biosensing in serum by Mathias Dolci, Paco Dreverman, Mildred S. Cano-Velázquez, Arthur L. Hendriks, Emiel Veth, P.J. van Veldhoven, Andrea Fiore, Peter Zijlstra

“…These referenced fiber-tip PhC biosensors may pave the way for fluidic integrated systems in environmental, industrial, and healthcare applications, and open up the possibility of biosensing in the human body by integrating them into catheters.…”
Get full text

How current law and policy supports providers of NHS healthcare in England to respond to patient harm: A scoping review protocol. by Naomi Assame, Susan Greenhalgh, John Tingle, Julie Wright, Gillian Yeowell

“…<h4>Introduction</h4>Harm arising from National Health Service (NHS) healthcare results in significant human cost for the patient, those who care for them, and the medical staff involved. …”
Get full text

Polyphenolic Compounds in Fabaceous Plants with Antidiabetic Potential by Lucia Guerrero-Becerra, Sumiko Morimoto, Estefania Arrellano-Ordoñez, Angélica Morales-Miranda, Ramón G. Guevara-Gonzalez, Ana Angélica Feregrino-Pérez, Consuelo Lomas-Soria

“…To integrate these herbal remedies into modern medicine, further research on phenolic compound type, doses, efficacy, and safety in the human population is needed.…”
Get full text

Role of the Psi Packaging Signal and Dimerization Initiation Sequence in the Organization of Rous Sarcoma Virus Gag-gRNA Co-Condensates by Gregory S. Lambert, Rebecca J. Kaddis Maldonado, Leslie J. Parent

“…Recent studies have demonstrated that the Gag proteins of Rous sarcoma virus (RSV) and human immunodeficiency virus type-1 (HIV-1) undergo nuclear trafficking, colocalize with nascent genomic viral RNA (gRNA) at transcription sites, may interact with host transcription factors, and display biophysical properties characteristic of biomolecular condensates. …”
Get full text