Genomic Variability among Field Isolates and Laboratory-Adapted Strains of Leptospira borgpetersenii Serovar Hardjo by Alejandro Llanes, Carlos Mario Restrepo, Pablo Riesgo-Ferreiro, Sreekumari Rajeev

“…Leptospira borgpetersenii serovar Hardjo colonizes cattle kidneys and may occasionally infect humans and other mammals. Strains belonging to two clonal subtypes (types A and B) with marked differences in their pathogenicity in the hamster experimental model have been described for this serovar. …”
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HAVCR1 Affects the MEK/ERK Pathway in Gastric Adenocarcinomas and Influences Tumor Progression and Patient Outcome by Ji Xue, Ying Li, Jianfeng Yi, Hong Jiang

“…Especially, HAVCR1 overexpression promotes the development and progression of several human cancers. Hence, we aimed to detect the effects of HAVCR1 on gastric adenocarcinoma (GAC). …”
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Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- Mice by Ying Huang, Haiying Hu, Ling Liu, Jing Ye, Zhen Wang, Bin Que, Wenjing Liu, Ying Shi, Tao Zeng, Lei Shi, Qingwei Ji, Chao Chang, Yingzhong Lin

“…Previous studies demonstrated that both recombinant mice and human IL-35 attenuated atherosclerosis in ApoE-/- mice. …”
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Testicular Cancer Presenting as Gastric Variceal Hemorrhage by Carlos Eduardo Salazar-Mejía, David Hernández-Barajas, Edio Llerena-Hernández, José Luis González-Vela, María Inés Contreras-Salcido, Adriana González-Gutiérrez, Omar David Borjas-Almaguer, Luis Alberto Pérez-Arredondo, Blanca Otilia Wimer-Castillo

“…The serum alpha-fetoprotein level was 17,090 ng/mL, lactate dehydrogenase was 1480 U/L, and human chorionic gonadotropin was 287.4 IU/mL. Upper endoscopy revealed a type 1 isolated gastric varix, treated with cyanoacrylate. …”
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Agent-Based Modeling of Harvest Decisions by Small Scale Forest Landowners in Maine, USA by Jessica E. Leahy, Erika Gorczyca Reeves, Kathleen P. Bell, Crista L. Straub, Jeremy S. Wilson

“…Small-scale forests are an excellent example of coupled social-ecological systems, which involve human and biophysical subsystems with complex two-way feedback interactions. …”
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Detection and Analysis of Autoantigens Targeted by Autoantibodies in Immunorelated Pancytopenia by Hui Liu, Rong Fu, Yihao Wang, Hong Liu, Lijuan Li, Honglei Wang, Jin Chen, Hong Yu, Zonghong Shao

“…This study identified that a G-protein-coupled receptor 156 variant and chain P, a crystal structure of the cytoplasmic domain of human erythrocyte band-3 protein, were autoantigens in IRP. …”
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From sick old man to mythical hero by Sandra Pitcher, Tammy Frankland, Nicola Jones

“…In an examination of the Independent Online news repository in 2010 and 2013, this research highlights how ‘Madiba’s Magic’ was a carefully constructed media image and one that, during his long illness, forced South Africans, and the world, to recognise his ‘humanness’. The paper concludes, however, by documenting the immense power of Mandela’s legacy as played out in the press, and how, after death, his carefully constructed legacy rose above the damage of his prolonged illness, elevating him from a sick old man and reinforcing him as a mythical revolutionary. …”
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Temporal-spatial evolution and formation mechanism of energy consumption carbon footprint at county scale in the Yellow River Basin by Liyan Zhang, Mei Song, Yan Gao

“…Government intervention, urbanization, human capital, and agricultural energy inputs increase the carbon footprint.…”
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Deep Learning for Predicting Spheroid Viability: Novel Convolutional Neural Network Model for Automating Quality Control for Three-Dimensional Bioprinting by Zyva A. Sheikh, Oliver Clarke, Amatullah Mir, Narutoshi Hibino

“…However, current viability assays are time-consuming, labor-intensive, require specialized training, or are subject to human bias. In this study, we build a convolutional neural network (CNN) model to efficiently and accurately predict spheroid viability, using a phase-contrast image of a spheroid as its input. …”
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A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial by Lewis Musoke, Hayden B. Bosworth, Christina Dickson, Pamela Gentry, Elizabeth Strawbridge, Soumya Subramaniam, Jennifer Gierisch, Valerie Smith, Sandra Woolson, John Pura, Willington Amutuhaire, Susanna Naggie, Julie Schexnayder, Karen Hall, Chris T. Longenecker, Nadine M. Harris, Chantrice Rogers, Puja Van Epps, for V-EXTRA-CVD Group

“…We aim to conduct a randomized control trial among PWH (n = 300) with a diagnosis of hypertension (HTN) who are enrolled in Veterans Health Administration (VHA) clinics, on suppressive antiretroviral therapy (ART), randomized 1:1 to intervention vs. education control for a 12-month duration. Methods: Using human centered design approach, we have adapted a previous 5-component telehealth focused, non-physician led intervention to a Veteran population. …”
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Identification of Sources of Resistance for Peanut Aspergillus flavus Colonization and Aflatoxin Contamination by Richard Moise Alansou Dieme, Issa Faye, Yedomon Ange Bovys Zoclanclounon, Daniel Fonceka, Ousmane Ndoye, Papa Madiallacke Diedhiou

“…Peanut aflatoxin contamination caused by Aspergillus flavus is a serious constraint for food safety and human health in Senegal. The present study aimed to identify sources of resistance for A. flavus colonization and aflatoxin contamination. …”
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High-Fiber Crackers Supplemented with Asparagus Hard-Stem: Impacts of Supplementation Ratios and Water Amounts in Cracker Recipe on the Product Quality by Thi Thu Tra Tran, Le Hong Ngoc Ngo, Nu Minh Nguyet Ton, Thi Hong Nhung Le, Thi Thuy Le, Van Viet Man Le

“…Spears or cladophylls are edible parts of asparagus ( Asparagus officinalis L.) implemented in a human diet while its hard-stem by-products have been used for animal feeding. …”
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Identification of Iron Homeostasis Genes Dysregulation Potentially Involved in Retinopathy of Prematurity Pathogenicity by Microarray Analysis by Xian-qiong Luo, Chun-yi Zhang, Jia-wen Zhang, Jing-bo Jiang, Ai-hua Yin, Li Guo, Chuan Nie, Xu-zai Lu, Hua Deng, Liang Zhang

“…Therefore, here we performed global gene expression profiling in human fetal retinal microvascular endothelial cells (RMECs) under hypoxic conditions in vitro. …”
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Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach by Kelly K. Gurka, Heather H. Burris, Lucia Ciciolla, Claire D. Coles, Suena H. Massey, Sharlene Newman, Vidya Rajagopalan, Lynne M. Smith, Anna Zilverstand, Gretchen Bandoli

“…The Healthy Brain and Child Development (HBCD) Study, a multi-site, prospective, longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. …”
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Influence of Exposure to Benzo[a]pyrene on Mice Testicular Germ Cells during Spermatogenesis by Hueiwang Anna Jeng, Silvina M. Bocca

“…However, the mice dose concentrations were not relevant for comparison to human exposure.…”
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Characterization of Women with Endocrine Infertility by Annia Quintana Marrero, Elodia María Rivas Alpízar, Jan Oneil González Ramos

“…<strong><br />Objective:</strong> to describe the behavior of endocrine female infertility in patients studied at the Territorial Center for Human Reproduction of Cienfuegos. <strong><br />Method:</strong> a descriptive series of case studies was conducted in which all women treated for endocrine infertility from January 2012 to January 2013 were included. …”
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Tryptophan as a biomarker of pregnancy-related immune expression and modulation: an integrative review by Stephanie Prescott, Stephanie Prescott, Natasa Billeci, Melissa Gotcher, Sapna Patel, Addison Almon, Hailey Morgan, Danielle Abukhalaf, Maureen Groer

“…The immunomodulatory role of TRP and its metabolites through the indoleamine 2,3-dioxygenase (IDO) pathway is particularly relevant to pregnancy due to its potential influence on maternal and fetal immune tolerance and the mother's health.MethodsA targeted literature search was conducted via PubMed, Web of Science, and Embase, focusing on maternal serum TRP levels in pregnancy. We included original human subject research on maternal serum TRP, published in English within the last five years. …”
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Comparative assessment of the resilience of new urban settlements to earthquake risk (Case study: Greater Isfahan urban area) by Fazllollah Karimi Ghotbabadi, Ali Zangiabadi

“…Consequently, to mitigate the adverse effects of earthquakes on communities, it is imperative to consider the unique capacities of each urban development, thereby reducing potential human and financial losses resulting from such events.…”
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Hepatitis B Virus (HBV) Genotypes in an Ecuadorian Population: A Preliminary Study by Miguel Moncayo, Enrique Teran, Bernardo Gutierrez, Jorge Reyes, Johanna Cortez, Rodrigo Tobar, Gabriela Yerovi, Marcia Robalino, Ana Aguilar, Daniel Garzon-Chavez

“…To address this gap, the current study took a preliminary look at HBV-infected human samples from this region to identify the most common genotypes and subgenotypes. …”
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Therapeutic Potential of Dental Pulp Stem Cell Secretome for Alzheimer’s Disease Treatment: An In Vitro Study by Nermeen El-Moataz Bellah Ahmed, Masashi Murakami, Yujiro Hirose, Misako Nakashima

“…Alzheimer’s disease (AD) is one of the most common human late onset and sporadic neurodegenerative disorders. …”
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