In vitro effects of ascorbic acid on viability and metabolism of patients’ osteosarcoma stem cells by Jovičić Marijana Šimić, Pušić Maja, Antunović Maja, Ledinski Maja, Librenjak Lucija, Kolundžić Robert, Ribičić Tomislav, Trkulja Vladimir, Urlić Inga

“…Determination of the dominant type of metabolism of OS-CSC, parental OS cells, human mesenchymal stem cells (hMSC) and U2OS OS lineage before and after AA treatment was done by Seahorse XF (Agilent). …”
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An Effective Methodology for Diabetes Prediction in the Case of Class Imbalance by Borislava Toleva, Ivan Atanasov, Ivan Ivanov, Vincent Hooper

“…Diabetes causes an increase in the level of blood sugar, which leads to damage to various parts of the human body. Diabetes data are used not only for providing a deeper understanding of the treatment mechanisms but also for predicting the probability that one might become sick. …”
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Prospects for the use of <i>Bacillus anthracis</i> toxin in cancer therapy by A. P. Rodionov, S. V. Ivanova, E. A. Artemeva, L. A. Melnikova

“…Cancer is one of the major causes of death in pet animals and humans worldwide. The contraindications and side effects associated with conventional cancer therapies heighten the importance of research aimed at finding new ways to combat cancer. …”
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Analysis of Spatial Distribution Pattern and Driving Factors of Nature Reserves in Xinjiang by Yue Yang, Zhaoping Yang, Fang Han

“…This spatial differentiation is the result of the interaction between natural and human factors, manifesting as an enhanced effect among these factors.…”
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Microbial and Inflammatory Salivary Biomarkers of Periodontal Diseases by Aram Mohammed Sha, Hayder Raad Abdulbaqi, Syed Saad Bin Qasim

“… Recent data reveals that severe periodontal diseases affect approximately 19% of global adult populations, impacting more than 1 billion individuals universally, ranking it as the sixth most predominant human disease. Diagnosis and treatment plans for periodontal disease entirely depend solely on the assessment of traditional clinical parameters. …”
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<i>In Silico</i> Investigation of γ-Sitosterol Isolated from the Ethanol Extract of <i>Artocarpus camansi</i> Leaves as a Sunscreen Agent by Rosnani Nasution, Rafna Azura, Muhammad Bahi, Nur Balqis Maulydia, Reza Akbar Bastian, Michelia Mutiara Hilda, Marianne Marianne

“…From the molecular docking, it is known that γ-sitosterol has the highest binding affinity value of −7.4 and −8.2 kcal/mol to human neutrophile collagenase (PDB ID: 1BZS) and fibroblast collagenase-1 (PDB ID: 966C), respectively. …”
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Regulator of Calcineurin 1 in Periodontal Disease by Ulrike Peters, Eleni Solominidou, Yüksel Korkmaz, Stefan Rüttermann, Astrid Klocke, Thomas Frank Flemmig, Thomas Beikler

“…For expression analysis human umbilical vein endothelial cells (HUVEC) were used. …”
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Gender Variations in the Oral Microbiomes of Elderly Patients with Initial Periodontitis by Jie Zhao, Ying-Hui Zhou, Ya-Qiong Zhao, Yao Feng, Fei Yan, Zheng-Rong Gao, Qin Ye, Yun Chen, Qiong Liu, Li Tan, Shao-Hui Zhang, Jing Hu, Marie Aimee Dusenge, Yun-Zhi Feng, Yue Guo

“…The oral microbiome influences human health. The aim of this study was at assessing gender variation in the subgingival bacterial microbiome of elderly patients with initial periodontitis and to determine the causes of this variation. …”
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Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease by Lindsey Van Haute, Petra Páleníková, Jia Xin Tang, Pavel A Nash, Mariella T Simon, Angela Pyle, Monika Oláhová, Christopher A Powell, Pedro Rebelo-Guiomar, Alexander Stover, Michael Champion, Charulata Deshpande, Emma L Baple, Karen L Stals, Sian Ellard, Olivia Anselem, Clémence Molac, Giulia Petrilli, Laurence Loeuillet, Sarah Grotto, Tania Attie-Bitach, Jose E Abdenur, Robert W Taylor, Michal Minczuk

“…Abstract Pathogenic variants in either the mitochondrial or nuclear genomes are associated with a diverse group of human disorders characterized by impaired mitochondrial function. …”
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Activity of Phosvitin in Hydroxyapatite Acid-Damage Immersion and Antimicrobial Assays by Richard D. Shipman, Sean D. Doering, Jack R. Hemsath, Eun Joo Lee, Jennifer E. Grant

“…In both Kirby–Bauer tests and liquid culture growth inhibition assays, phosvitin inhibited M. luteus, a microorganism that thrives in the human mouth, but not the other bacteria tested. The MIC of phosvitin was determined to be 31.3 μg/mL when delivered in 1 mM CaCl2 but was 0.5 mg/mL in the absence of added calcium. …”
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Prion Diseases and the Gastrointestinal Tract by Gwynivere A Davies, Adam R Bryant, John D Reynolds, Frank R Jirik, Keith A Sharkey

“…The gastrointestinal (GI) tract plays a central role in the pathogenesis of transmissible spongiform encephalopathies. These are human and animal diseases that include bovine spongiform encephalopathy, scrapie and Creutzfeldt-Jakob disease. …”
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Serum Micronutrient Status of Haart-Naïve, HIV Infected Children in South Western Nigeria: A Case Controlled Study by H. C. Anyabolu, E. A. Adejuyigbe, O. O. Adeodu

“…Though micronutrients are vital in the pathogenesis of human immunodeficiency virus infection, most studies have been conducted in adults. …”
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Prenatal Stress due to a Natural Disaster Predicts Adiposity in Childhood: The Iowa Flood Study by Kelsey N. Dancause, David P. Laplante, Kimberly J. Hart, Michael W. O’Hara, Guillaume Elgbeili, Alain Brunet, Suzanne King

“…Prenatal stress can affect lifelong physical growth, including increased obesity risk. However, human studies remain limited. Natural disasters provide models of independent stressors unrelated to confounding maternal characteristics. …”
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Different Pathological Roles of Toll-Like Receptor 9 on Mucosal B Cells and Dendritic Cells in Murine IgA Nephropathy by Tadahiro Kajiyama, Yusuke Suzuki, Masao Kihara, Hitoshi Suzuki, Satoshi Horikoshi, Yasuhiko Tomino

“…We have reported that mucosal toll-like receptor (TLR)-9 is involved in the pathogenesis of human and murine IgAN. However, cell-type expressing TLR9 in mucosa remains unclear. …”
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Case report: Bevacizumab-induced cerebrovascular events: a case series report and literature review by Ke Chen, Boyang Jiang, Boyang Jiang, Huiping Yan, Huiping Yan, Liu Yang, Liu Yang, Zheling Chen, Zheling Chen

“…In clinical use, bevacizumab has improved the overall survival (OS) and progression-free survival (PFS) of malignant solid tumors, and the safe use of bevacizumab has gradually become the mainstream direction of clinical, nursing and pharmaceutical research. Bevacizumab is a humanized anti-VEGF drug. By binding to VEGF, it loses the opportunity to activate VEGFR and then plays an anti-angiogenic role. …”
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Autologous and Heterologous Minor and Major Bone Regeneration with Platelet-Derived Growth Factors by Gianna Dipalma, Angelo Michele Inchingolo, Valeria Colonna, Pierluigi Marotti, Claudio Carone, Laura Ferrante, Francesco Inchingolo, Andrea Palermo, Alessio Danilo Inchingolo

“…Only English-language clinical studies involving human subjects were included. A total of 10 studies were selected for qualitative analysis. …”
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Research on Airport Target Recognition under Low-Visibility Condition Based on Transfer Learning by Jiajun Li, Yongzhong Wang, Yuexin Qian, Tianyi Xu, Kaiwen Wang, Liancheng Wan

“…From the perspective of transfer learning, this paper will explore the identification of all targets (mainly including aircraft, humans, ground vehicles, hangars, and birds) in the airport field under low-visibility conditions (caused by bad weather such as fog, rain, and snow). …”
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Sulforaphane in alternative cancer chemotherapy: From carcinogenesis suppression to drug resistance reversal by Seyed Mohammad Doodmani, Payman Rahimzadeh, Najma Farahani, Seyedalireza Mirilavasani, Mina Alimohammadi, Noushin Nabavi, Elmira Alaei, Afshin Taheriazam, Maryam Abedi, Nadia Shafiee, Salman Daneshi, Mehrdad Hashemi

“…When combined with chemotherapy drugs, SFN enhances tumor suppression and mitigates drug resistance in human cancers. This is achieved primarily by promoting apoptosis, reducing proliferation, and inhibiting metastasis. …”
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Functional connectome gradient of prefrontal cortex as biomarkers of high risk for internet gaming disorder by Xinwen Wen, Lirong Yue, Zhe Du, Jiahao Zhao, Mengjiao Ge, Cunfeng Yuan, Hongmei Wang, Qinghua He, Kai Yuan

“…We used functional connectome gradient (FCG) to capture the macroscopic hierarchical organization of human brain. Canonical correlation analysis was employed to identify components mapping relationships between FCG and behavioral scores. …”
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Statistical Distribution of Urban Area Reveals a Converging Trend of Global Urban Land Expansion by Shengjie Hu, Zhenlei Yang, Sergio Andres Galindo Torres, Zipeng Wang, Haoying Han, Yoshihide Wada, Thomas Cherico Wanger, Ling Li

“…Abstract Urban land expansion is a major driver of many environmental and societal changes that challenge human well‐being and sustainable development, but its evolutionary process and dynamics are neither clear nor well‐integrated into urban science quantitatively. …”
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