Evaluation of Regulatory Immune Response in Skin Lesions of Patients Affected by Nonulcerated or Atypical Cutaneous Leishmaniasis in Honduras, Central America by Gabriela Venicia Araujo Flores, Carmen Maria Sandoval Pacheco, Thaise Yumie Tomokane, Wilfredo Sosa Ochoa, Concepción Zúniga Valeriano, Claudia Maria Castro Gomes, Carlos Eduardo Pereira Corbett, Marcia Dalastra Laurenti

“…Considering that little is known about the pathogenesis of NUCL, the aim of this study was to evaluate the regulatory response in situ in skin lesions of patients affected by NUCL. Biopsies (n=20) from human cutaneous nonulcerative lesions were collected and processed by usual histological techniques. …”
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Towards a Bipolar World. Book Review of ‘The Second World War and the Transformation of International Relations: From Multipolarity to a Bipolar World’ edited by L.S. Belousov and... by V. I. Batyuk

“…In 2020 the whole world commemorated the 75th anniversary of the end of World War II — the most horrifi c war in the human history. However, the celebration of the victory over fascism was overshadowed by the growing tension among the leading actors of contemporary international relations. …”
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Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus by Yifan Xing, Zeyu Wen, Jie Mei, Xinyi Huang, Shuangshuang Zhao, Jin Zhong, Yaming Jiu

“…Abstract Hepatitis C virus (HCV) is a major human pathogen causing liver diseases. Although direct‐acting antiviral agents effectively inhibit HCV infection, cell–cell transmission remains a critical venue for HCV persistence in vivo. …”
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IncF Plasmids Are Commonly Carried by Antibiotic Resistant Escherichia coli Isolated from Drinking Water Sources in Northern Tanzania by Beatus Lyimo, Joram Buza, Murugan Subbiah, Sylivester Temba, Honest Kipasika, Woutrina Smith, Douglas R. Call

“…Detection of these public health-relevant conjugative plasmids and antibiotic resistant traits in Tanzanian water suggests the possible pollution of these water sources from human, livestock, and wild animal wastes and also shows the potential of these water sources in the maintenance and transmission of these resistance traits between environments, animals, and people.…”
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Automated Measurements of Tooth Size and Arch Widths on Cone-Beam Computerized Tomography and Scan Images of Plaster Dental Models by Thong Phi Nguyen, Jang-Hoon Ahn, Hyun-Kyo Lim, Ami Kim, Jonghun Yoon

“…An analysis of variance test confirmed the statistical consistency between the method’s measurements and those of human experts.…”
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Clopidogrel Protects Endothelium by Hindering TNFα-Induced VCAM-1 Expression through CaMKKβ/AMPK/Nrf2 Pathway by Huabing Yang, Pengjun Zhao, Shiliu Tian

“…In the present study, human aortic endothelial cells (HAECs) were employed to explore the anti-inflammatory activity of INN. …”
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Machine Learning-Based Diabetes Risk Prediction Using Associated Behavioral Features by Ayodeji O. J. Ibitoye, Joseph D. Akinyemi, Olufade F. W. Onifade

“…With different uncertainties in human lifestyles, it is difficult to predict diabetes while assuming that the risk patterns are the same for all. …”
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دور دار الوثائق القومیة فى التسویق للتراث الوطنى الوثائقى فى مصر : دراسة تحلیلیة by د. مریم صالح منصور

“…National archives play a pivotal role in documenting the historical memoryof human beings and have the capacity to change the social, economic andpolitical development of the people. …”
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Monitoring ocular disease via optical nanostructures potentially applicable to corneal contact lens products by Bader AlQattan, Mohamed Elsherif, Fahad Alam, Haider Butt

“…A spherical surface was also used to simulate the human eye, and application of a force (curvature change) caused the nanostructure spacing to change, influencing the visible color of the contact lenses. …”
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HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas by M. J. Rutten, F. Dijk, C. D. Savci-Heijink, M. R. Buist, G. G. Kenter, M. J. van de Vijver, E. S. Jordanova

“…Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. …”
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Households willingness to pay for improved solid waste management by S. Akhtar, A.S. Ahmad, M.I. Qureshi, S. Shahraz

“…Waste is a byproduct of human life. Nowadays, municipal solid waste is being produced in excessive amounts and in this way, both developing and developed countries are facing challenges regarding generation of waste. …”
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Clinicopathologic Significance of HIF-1α, CXCR4, and VEGF Expression in Colon Cancer by Yugang Wu, Min Jin, Huanbai Xu, Zhang Shimin, Songbing He, Liang Wang, Yanyun Zhang

“…We investigated the clinicopathologic significance of HIF-1, CXCR4, and VEGF expression using immumohistochemistry in human colon cancer. HIF-1, CXCR4, and VEGF high expression levels were correlated positively with TNM stage, lymph node involvement, and distant metastasis Furthermore, we found that combined high expression of any two of the three molecules (P=.028 for HIF-1/CXCR4, P=.007 for HIF-1/VEGF, and P=.004 for CXCR4/VEGF) had stronger correlation with lymph node metastasis than did each alone. …”
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Challenges in Emerging Vaccines and Future Promising Candidates against SARS-CoV-2 Variants by Tanmay Ghildiyal, Nishant Rai, Janhvi Mishra Rawat, Maargavi Singh, Jigisha Anand, Gaurav Pant, Gaurav Kumar, Amrullah Shidiki

“…Genomic variation can be quite significant, as seen by the notable differences in impact, transmission rate, morbidity, and death during several human coronavirus outbreaks. Therefore, understanding the amount and characteristics of coronavirus genetic diversity in historical and contemporary strains can help researchers get an edge over upcoming variants.…”
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Potential of Louhan fish (Amphilophus labiatus) as a local fishery pest in Lake Toba North Sumatra as a source omega 3 and 6 fatty acids by Pandiangan Maruba, Sihombing Dewi Restuana, Daniela Connie, Sibuea Posman, Tampubolon Sanggam Dera Rosa, Sitohang Apul, Sitanggang Lasmianna

“…Louhan fish oil may include omega 3 and omega 6 fatty acids, which are beneficial to human health, based on its fatty acid composition.…”
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Legal Certainty – Protected Values and Partial Objectives: The Case of the Czech Republic by Jana Janderová, Petra Hubálková

“…Its objective is to promote several values that are all important for the protection of human rights: the rule of law, protection of legitimate expectations, general trust in law, prevention of arbitrary decision-making, inadmissibility of retroactivity. …”
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Renal and Hematological Effects of CLCF-1, a B-Cell-Stimulating Cytokine of the IL-6 Family by Virginia J. Savin, Mukut Sharma, Jianping Zhou, David Gennochi, Timothy Fields, Ram Sharma, Ellen T. McCarthy, Tarak Srivastava, Jos Domen, Aurélie Tormo, Jean-François Gauchat

“…We have identified CLCF-1 as a potential injurious factor in the human renal disease focal segmental glomerulosclerosis (FSGS). …”
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Parameters Estimation of a Microscopic Traffic Flow Sub-Model Within a Multiscale Approach Using Experimental Data by Facundo Storani, Roberta Di Pace, Shi-Teng Zheng, Rui Jiang, Stefano de Luca

“…Future traffic contexts will likely involve the coexistence of human-driven vehicles and connected and automated vehicles (CAVs). …”
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cLegal-QA: a Chinese legal question answering with natural language generation methods by Yizhen Wang, Xueying Shen, Zixian Huang, Lihui Niu, Shiyan Ou

“…This dataset spans various legal disputes and includes questions, disputes, scenarios, multiple lawyer responses, and gold-standard answers from human annotators. Additionally, we employed a generative QA model specifically designed for the cLegal-QA dataset. …”
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The Effect of Using Cement Kiln Dust as a Partial Replacement of Cement on The Mechanical Properties of Concrete: Review and Modelling by Nawdar Sabir Faraj, Mahdi Osman Hassun

“…These efforts have been made due to the necessity of the material for proper disposal, because of its very fine texture and the fact that if not handled properly, it will be harmful to human health and the environment. Numerous studies have been conducted to investigate the effects of incorporating CKD in concrete as an approach of reusing it. …”
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Protected Turning Movements of Noncooperative Automated Vehicles: Geometrics, Trajectories, and Saturation Flow by Xiaobo Liu, Lijuan Lai, You Kong, Scott Le Vine

“…We analyze noncooperative (“defensive”) behavior, in keeping with the Assured Clear Distance Ahead legal standard to which human drivers are held and AVs will likely also be for the foreseeable future. …”
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