Production of an Extract with β-1,4-Xylanase Activity by <i>Fusarium oxysporum</i> f. sp. <i>melonis</i> on a Sonicated Brewer’s Spent Grain Substrate by Irma A. Arreola-Cruz, Rosalba Troncoso-Rojas, Francisco Vásquez-Lara, Nina G. Heredia-Sandoval, Alma R. Islas-Rubio

“…The <i>Fusarium oxysporum</i> species commonly found in soil include plant and human pathogens, and nonpathogenic species. <i>F. oxysporum</i> grown on lignocellulosic substrates under submerged conditions produces an extracellular enzyme profile with hemicellulolytic and cellulolytic activities. …”
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Symptom Status Predicts Patient Outcomes in Persons with HIV and Comorbid Liver Disease by Wendy A. Henderson, Angela C. Martino, Noriko Kitamura, Kevin H. Kim, Judith A. Erlen

“…Persons living with human immunodeficiency virus (HIV) are living longer; therefore, they are more likely to suffer significant morbidity due to potentially treatable liver diseases. …”
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Atomic Force Microscopy (AFM) nanomechanical characterization of micro- and nanoplastics to support environmental investigations in groundwater by Massimiliano Galluzzi, Michele Lancia, Chunmiao Zheng, Viviana Re, Valter Castelvetro, Shifeng Guo, Stefano Viaroli

“…Micro and nanoplastic (MNP) pollution is a severe environmental issue, posing potential risks to environmental and human health due to the intrinsic toxicity of plastic particles and their capacity to adsorb other pollutants. …”
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Sargassum plagiophyllum Ethanolic Extract Enhances Wound Healing by Modulating FAK/Src/Akt/p38 and Rac1 Signaling in Keratinocytes HaCaT Cells by Furoida Moolsup, Wanida Sukketsiri, Wipawadee Sianglum, Jirawat Saetan, Nattakanwadee Khumpirapang, Supita Tanasawet

“…This study, therefore, aimed to explore phytochemical analysis, antimicrobial, antioxidant, and wound healing properties of brown seaweed Sargassum plagiophyllym ethanolic extract (SPEE) on human skin keratinocyte HaCaT cells and the possible mechanism involved. …”
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Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death by Jialin Dai, Jiangjin Liu, Qiong Zhang, Yang An, Bing Xia, Changwu Wan, Yuanyuan Zhang, Yanni Yu, Jie Wang

“…It provides a proteomic analysis of human left anterior descending coronary artery from subjects diagnosed with SCD through histological examination and cases of nondisease accidental deaths through autopsy. …”
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Intelligent methods for natural data analysis: application to space weather by O.V. Mandrikova

“…The negative impact of space weather anomalies on human health and practically all modern infrastructure objects requires the development of methods and the creation of effective means of detecting anomalies. …”
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Adolescents: Contraceptive Knowledge and Use, a Brazilian Study by Divanise S. Correia, Ana C. P. Pontes, Jairo C. Cavalcante, E. Sócrates T. Egito, Eulália M.C. Maia

“…This study was approved by the Human Research Ethics Committee, and Epi InfoTM software was used for data and result evaluation using the mean and chi-square statistical test. …”
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Investigation of Air Quality and the Effects of Meteorological Factors on Air Pollution in Nevşehir Province by Kahraman Oğuz

“…Increasing urban air pollution causes important problems affecting the environment and human health. One of the most important sources of urban air pollution is the road transport sector. …”
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New derivatives of sulfonylhydrazone as potential antitumor agents: Design, synthesis and cheminformatics evaluation by Sabbah Dima A., Al-Azaideh Bara’a A., Talib Wamidh H., Hajjo Rima, Sweidan Kamal, Al-Zuheiri Aya M., Sheikha Ghassan Abu, Shraim Sawsan

“…Target compounds exhibited an antiproliferative effect against the human colon carcinoma (HCT-116) cell line. Our cheminformatics analysis indicated that the para-tailored derivatives [p-NO2 (3) and p-CF3 (7)] have better ionization potentials based on calculated Moran autocorrelations and ionization potentials. …”
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Limits and Risks of Digital Transformation by T. S. Akhromeeva, G. G. Malinetskiy, S. A. Posashkov

“…It happens when artificial intelligence systems are assigned strategically important tasks that they must solve at a speed inaccessible to humans.The analysis shows that managing the risks of digital transformation and its limitations requires the attention of the scientific and expert community, as well as active participants in this process.…”
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Analysis of Roadside Land Use Changes and Landscape Ecological Risk Assessment Based on GF-1: A Case Study of the Linghua Expressway by Mengdi Wen, Liangliang Zhang, Huawei Wan, Peirong Shi, Longhui Lu, Zixin Zhao, Zhiru Zhang, Jinhui Wu

“…Landscape ecological risk assessment, as an important means to predict and measure the adverse effects of human activities on the ecological environment, is being paid more and more attention. …”
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Buildings, Causalities, and Injuries Innovative Fuzzy Damage Model during Earthquakes by Mohammad Reza Amiri Shahmirani, Abbas Akbarpour Nikghalb Rashti, Mohammad Reza Adib Ramezani, Emadaldin Mohammadi Golafshani

“…One of the human concerns has always been to estimate the damage caused before the earthquake and predict the extent of injuries and causalities. …”
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Clinical Application of Development of Nonantibiotic Macrolides That Correct Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases by Carmen Rodriguez-Cerdeira, Elena Sanchez-Blanco, Alberto Molares-Vila

“…Inflammation-driven immune dysfunction supports the development of several chronic human disorders including skin diseases. Nonantibiotic macrolides have anti-inflammatory and/or immunomodulatory activity that suggests the exploitation of these in the treatment of skin diseases characterized by inflammatory disorders. …”
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Intratympanic administration of dexamethasone attenuates radiation induced damage to middle ear mucosa by Hyuk Chan Kwon, Sup Kim, Sheng Jin, Sun-Ae Shin, Jeong Han Lee, Min Jung Park, Soo Jeong Kim, Yong-Ho Park

“…The present study investigated the effects and underlying mechanisms of DEX delivered via intratympanic administration on RTx-induced damage to the middle ear and human middle ear epithelial (HMEE) cells. Sprague–Dawley (SD) rats were exposed to fractionated RTx (6.6 Gy/day for 5 days), and middle ear samples were collected at 1 and 4 months. …”
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Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration by Paul Tamburini, Dennis Vestergaard Pedersen, Denise Devore, Josh Cone, Rekha Patel, Todd Hunter, Fang Sun, Gregers Rom Andersen, Jeffrey Hunter

“…Tarperprumig incorporates a C-terminal variable domain of a heavy chain only antibody (VHH) that binds properdin (FP) connected via a flexible linker to an N-terminal VHH that binds human serum albumin (HSA). The purified bispecific VHH antibody exhibits an experimental molecular weight average of 27.4 kDa and can be formulated at > 100 mg/mL. …”
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Protocol for a qualitative study to explore acceptability, barriers and facilitators of the implementation of new teleophthalmology technologies between community optometry practic... by Ann Blandford, Konstantinos Balaskas, Rima Hussain, Sarah Abdi, Angela Aristidou, Josie Carmichael, Giulia Cappellaro

“…Findings will be reported through academic journals and conferences in ophthalmology, health services research, management studies and human-computer interaction.…”
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Congenital cytomegalovirus - current state of knowledge on the treatment and prevention of fetuses and newborns by Katarzyna Miedzińska, Mateusz Grego, Łukasz Stojak, Dariusz Popiela, Karina Urbańska, Filip Kwiatkowski, Mateusz Baczewski, Witold Czyż

“… Cytomegalovirus (CMV)  is common  pathogen in the human population and one of the most  causes of intrauterine infections of the fetus. …”
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Characterization of the Sodium Multi-Vitamin Transporter in the Mosquito <i>Anopheles stephensi</i> and Its Capacity to Mobilize Pantothenate and Biotin by Jun Isoe, Brendan F. Riske, Megan E. Dobson, Hannah L. Kaylor, Jessica C. Brady, Yared Debebe, Laura M. Saavedra, Shirley Luckhart, Michael A. Riehle

“…In this work, we examined Pan levels in the important human malaria vector <i>Anopheles stephensi</i>, including the abundance of Pan during immature development and adulthood. …”
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Synthesis, antiproliferative and antiplasmodial evaluation of new chloroquine and mefloquine-based harmiquins by Pavić Kristina, Poje Goran, Carvalho Lais Pessanha De, Held Jana, Rajić Zrinka

“…Testing of the antiproliferative activity of the new UT harmiquins, and previously prepared triazole-(TT) and amide-type (AT) CQ-based harmiquins, against a panel of human cell lines, revealed TT harmiquine 16 as the most promising compound, as it showed pronounced and selective activity against the tumor cell line HepG2 (IC50 = 5.48 ± 3.35 μmol L−1). …”
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Photobiomodulation: An Effective Approach to Enhance Proliferation and Differentiation of Adipose-Derived Stem Cells into Osteoblasts by Daniella Da Silva, Anine Crous, Heidi Abrahamse

“…Osteoporosis is regarded as the most common chronic metabolic bone condition in humans. In osteoporosis, bone mesenchymal stem cells (MSCs) have reduced cellular function. …”
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