Atractylenolide I prevents acute liver failure in mouse by regulating M1 macrophage polarization by Hui Zhang, Min Gao, Haiyan Wang, Junfeng Zhang, Lin Wang, Guanjun Dong, Qun Ma, Chunxia Li, Jun Dai, Zhihua Li, Fenglian Yan, Huabao Xiong

“…A murine model of lipopolysaccharide (LPS)- and D-galactosamine (D-GalN)-induced ALF is widely used to investigate the underlying mechanisms and potential therapeutic drugs for human liver failure. Atractylenolide I (ATR-I) is an active component of the Atractylodes macrocephala rhizome and possesses various pharmacological activities, including anti-tumor, anti-inflammatory, and anti-oxidant properties. …”
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RTEL1 is upregulated in gastric cancer and promotes tumor growth by Chunyu Yang, Suzeng Wang, Ge Gao, Peiwen Xu, Mengyuan Qian, Yuan Yin, Surui Yao, Zhaohui Huang, Zehua Bian

“…However, the precise role of RTEL1 in human cancers, particularly in GC, is not yet fully understood. …”
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Unignorable Emissions and Potential Health Effects of Unregulated Pollutants from Nonroad Engines Using Greener Fuels — A Review by Lulu Duan, Yu-Lun Hsieh, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Muhammad Isyhraff Azhan Bin Mansor, Hyojun Lee, Chien-Er Huang, How-Ran Chao, Mengjie Song, Minseop Song

“…However, these machines also emit unregulated pollutants such as PAHs, VOCs, POPs, and metals, which severely impact human health and the atmosphere. A key strategy to reduce these emissions is using green fuels, including biodiesel, oxygenated fuels, metal additives, hydrogen, and ammonia. …”
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Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis by Yingshan Zeng, Zhiquan Wu, Mengtian Xiong, Zhishan Liang, Ziyu Chen, Huimin Huang, Hongyu Yang, Qingsong Chen

“…These results highlight Piezo1 and the NF-κB/p65 pathway as potential therapeutic targets for HAVS and underscore the need for further validation in human samples and exploration of additional signaling mechanisms involved in vibration-induced vascular injury.…”
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High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report by Tsuyoshi Okura, Etsuko Ueta, Risa Nakamura, Yohei Fujioka, Keisuke Sumi, Kazuhisa Matsumoto, Kyoko Shoji, Kazuhiko Matsuzawa, Shoichiro Izawa, Yuri Nomi, Hitomi Mihara, Yuzuru Otsuka, Masahiko Kato, Shin-ichi Taniguchi, Kazuhiro Yamamoto

“…We have developed a highly sensitive liquid chromatography-tandem mass spectrometry method for measuring AGEs in human serum. Here, we use this method to investigate the relationship between AGEs and insulin secretion and resistance in patients with T2DM. …”
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Evaluation of Housing Quality Indicators Using Analytic Network Process (ANP) by hossein mobarra, Mahsa Faramarzi Asli

“…Housing is a crucial domain for testing human interactions and serves as a physical framework where social, cultural, and economic resources intertwine. …”
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Automatic Coastline Detection Using Coastsat Toolbox and GIS: A Case Study at Oued-Laou Beach, Morocco by Souiri Smail, Hakkou Mounir, Haddaoui Hatim, Oubdil Soufiane, Lmrimed Nargiss

“…Coastal zones are vital ecosystems increasingly impacted by erosion and human activities. Accurate and timely shoreline mapping is essential for understanding coastal dynamics, predicting erosion, and guiding sustainable management strategies. …”
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Essential oil and furanosesquiterpenes from myrrh oleo-gum resin: a breakthrough in mosquito vector management by Eleonora Spinozzi, Marta Ferrati, Cecilia Baldassarri, Paolo Rossi, Guido Favia, Giorgio Cameli, Giovanni Benelli, Angelo Canale, Livia De Fazi, Roman Pavela, Luana Quassinti, Cristiano Giordani, Fabrizio Araniti, Loredana Cappellacci, Riccardo Petrelli, Filippo Maggi

“…The EO non-target toxicity on Daphnia magna Straus (LC50 = 4.51 μL/L) and its cytotoxicity on a human kidney cell line (HEK293) (IC50 of 14.38 μg/mL) were also assessed. …”
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Cultivable Actinobacteria First Found in Baikal Endemic Algae Is a New Source of Natural Products with Antibiotic Activity by Denis V. Axenov-Gribanov, Daria V. Kostka, Ulyana А. Vasilieva, Zhanna M. Shatilina, Maria E. Krasnova, Ekaterina V. Pereliaeva, Elena D. Zolotovskaya, Maria M. Morgunova, Olga O. Rusanovskaya, Maxim A. Timofeyev

“…Inadequate use of antibiotics has led to spread of microorganisms resistant to effective antimicrobial compounds for humans and animals. This study was aimed to isolate cultivable strains of actinobacteria associated with Baikal endemic alga Draparnaldioides baicalensis and estimate their antibiotic properties. …”
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Event Detection and Identification of Influential Spreaders in Social Media Data Streams by Leilei Shi, Yan Wu, Lu Liu, Xiang Sun, Liang Jiang

“…However, traditional event detection models require human intervention to detect the number of topics to be explored, which significantly reduces the efficiency and accuracy of event detection. …”
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PEMANFAATAN MEDIA MONOPOLI UNTUK MENINGKATKAN KEAKTIFAN DAN HASIL BELAJAR IPA SISWA KELAS III SDN SUGIHWARAS KECAMATAN MAOSPATI KABUPATEN MAGETAN TAHUN PELAJARAN 2015/2016 by Anang Gatot Subroto, R. Bekti Kiswardianta, M.S Djoko Laksana

“…Education is an important role in improving human resources. SDN Sugihwaras 2 Maospati have adequate facilities and infrastructure, but its use is not maximized. …”
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Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1 by Yong Li, Qi Zhang, Na Li, Liting Ding, Jinping Yi, Yue Xiao, Shibiao Chen, Xuan Huang

“…The protein level of Ataxin-10 is relatively higher in human vascular endothelial cells, which can be significantly suppressed by TNF-α in both HUVECs and HLMECs. …”
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Enhancing Miscanthus floridulus remediation of soil cadmium using Beauveria bassiana FE14: Plant growth promotion and microbial interactions by Ying Wang, Sha Xiang, Rui Chen, Liang Chen, Wendi Lan, Jun Fang, Yunhua Xiao

“…Soil heavy metal pollution presents substantial risks to food security and human health. This study focused on the efficiency of plant growth-promoting fungus-Beauveria bassiana FE14 and Miscanthus floridulus on the synergistic remediation of soil Cd contamination. …”
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IMPORTANCE OF POSTUROLOGY AS PREVENTION AND INTERVENTION FOR MUSCULOSKELETAL AND SPINAL DEFORMITIES by Petya Kasnakova, Biyanka Tornyova, Tanya Paskaleva

“…Conclusion: Posturology provides an opportunity for diagnosis, treatment and prevention of common joint and musculoskeletal injuries due to the interrelationships with other body systems. Correct human posture is one of the signs of good physical development and health.…”
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Successful Strategy in Creating Low-FODMAP Wholegrain Bread—Simple and Global by Aleksandra M. Torbica, Vesna Vujasinović, Uroš Miljić, Goran Radivojević, Bojana Filipčev, Milorad Miljić, Miloš Radosavljević

“…At the same time; bakery products are an important part of the human diet worldwide and the key contributors to the high intake of FODMAPs; especially in their wholegrain form. …”
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Model the allocation of productive financial resources from the perspective of livelihood poverty indicators using a combination of clustering methods and SAW technique by mehrdad Mohamadpour shatery, hoshang taghizadeh, sahar khoshfetrat

“…Poverty is a social, economic, cultural and political reality that has long been one of the greatest human problems. The diversity of problems, needs and problems of the deprived and low-income groups of the society and the multiplicity of poverty indicators on the one hand, and on the other hand the lack of financial resources and credits to solve the poverty indicators, organizations in charge of poor affairs, including Imam Khomeini Relief Committee Has faced serious challenges in the optimal allocation of resources. …”
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Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex by Harald Bernhard, Hana Petržílková, Barbora Popelářová, Kamil Ziemkiewicz, Karolina Bartosik, Marcin Warmiński, Laura Tengo, Henri Gröger, Luciano G. Dolce, Cameron D. Mackereth, Ronald Micura, Jacek Jemielity, Eva Kowalinski

“…Abstract Kinetoplastids are a clade of eukaryotic protozoans that include human parasitic pathogens like trypanosomes and Leishmania species. …”
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Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes by Daniel Espes, Mats Martinell, Per-Ola Carlsson

“…Future studies are clearly needed to delineate the exact role, if any, of betatrophin in regulating human beta-cell mass.…”
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Dynamics of <i>Nakaseomyces glabratus</i> biofilm formation by E. M. Lenchenko, N. P. Sachivkina, A. V. Liseitsev

“…Formation of biofilms of microorganisms, including those of Nakaseomyces glabratus, is responsible for the development of local and systemic pathologies in humans and animals. The system of gene expression coordination (quorum sensing) in the representation of signaling molecules allows regulation of the amount and composition of biofilm populations thus expanding the adaptive capacity of microorganisms. …”
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Effects of reproductive technologies and SPF status on some physiological and behavioral characteristics in rats with arterial hypertension (ISIAH strain) by D. S. Ragaeva, T. O. Abramova, I. N. Rozhkova, E. Yu. Brusentsev, E. V. Kalinichenko, T. N. Igonina, S. Ya. Amstislavsky

“…On the other hand, assisted reproductive technologies (ART) are widely used in modern medicine for human infertility treatment as well as for genome resource banking. …”
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