Phytochemical Screening and Biological Activity of Mentha × piperita L. and Lavandula angustifolia Mill. Extracts by Ersilia Alexa, Corina Danciu, Isidora Radulov, Diana Obistioiu, Renata Maria Sumalan, Adriana Morar, Cristina Adriana Dehelean

“…In terms of biological activity against MDA-MB-231 breast carcinoma cell line, and A375 human melanoma cell line, at the highest employed concentration, 150 μg·mL–1, the tested extracts present a weak antiproliferative effect.…”
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Why are women still leaving academic medicine? A qualitative study within a London Medical School by Christopher J Peters, Lesley Regan, Victoria Salem, Clare Lloyd, Dhruti Hirani

“…Thematic analysis was performed on the transcribed conversations.Participants and setting Nine women physicians who completed a postgraduate degree (MD or PhD) at a large London Medical School and Academic Health Sciences Centre, Imperial College London, but did not go on to pursue a career in academic medicine.Results Influences to leave clinical academia were summarised under eight themes—career intentions, supervisor support, institutional human resources support, inclusivity, work–life balance, expectations, mentors and role models, and pregnancy and maternity leave.Conclusion The women in our focus group reported several factors contributing to their decision to leave clinical academia, which included lack of mentoring tailored to specific needs, low levels of acceptance for flexible working to help meet parental responsibilities and perceived explicit gender biases. …”
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The percentage of Body Fat and its Relationship with Blood Pressure in Adults from Rural and Urban Areas by Carlos Enrique García Yerena, Omar Oliveros Rangel, Brian Johan Bustos Viviescas, Amalia Villamizar Navarro, John Alexander García Galviz

“…<strong>Foundation:</strong> excess body fat is marked by a permanent imbalance between food consumption and energy expenditure of human beings that generate various health risks, including increased blood pressure. …”
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Neuroplasticity of Acupuncture for Stroke: An Evidence-Based Review of MRI by Jinhuan Zhang, Chunjian Lu, Xiaoxiong Wu, Dehui Nie, Haibo Yu

“…After searching PubMed, Web of Science, and Embase databases, 24 human and five animal studies were identified. This review focuses on the evidence on the possible mechanisms underlying mechanisms of acupuncture therapy in treating stroke by regulating brain plasticity. …”
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Assessment of groundwater intrinsic vulnerability using GIS-based DRASTIC method in district Karak, Khyber Pakhtunkhwa, Pakistan by Muhammad Muneer, Mumtaz Ali Khan, Fayaz Ullah Shinwari, Ijaz Ahmed, Syed Mamoon Siyar, Fahad Alshehri, Muhammad Shahab

“…The concentration of Nitrate &gt;10 ppm represent that some human action has contributed toward the highest concentration.…”
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Stellettin B Isolated from Stelletta Sp. Reduces Migration and Invasion of Hepatocellular Carcinoma Cells through Reducing Activation of the MAPKs and FAK/PI3K/AKT/mTOR Signaling P... by Tsung-Chang Tsai, Wen-Tung Wu, Jen-Jie Lin, Jui-Hsin Su, Yu-Jen Wu

“…In this study, we used Stellettin B, an active compound isolated from Stelletta sponges, as the experimental drug and evaluated its inhibition effects on cell migration and invasion in human hepatoma cells (HA22T and HepG2). MTT assay, gelatin zymography, and western blotting were employed. …”
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Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples by HyoYoung Kim, Won Gi Yoo, Junhyung Park, Heebal Kim, Byeong-Chul Kang

“…Single-nucleotide polymorphisms (SNPs) have been emerging out of the efforts to research human diseases and ethnic disparities. A semantic network is needed for in-depth understanding of the impacts of SNPs, because phenotypes are modulated by complex networks, including biochemical and physiological pathways. …”
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Quantification of Malondialdehyde in Atmospheric Aerosols: Application of the Thiobarbituric Acid Method by David H. Gonzalez, Suzanne E. Paulson

“…Abstract Based on available toxicity data, malondialdehyde (MDA; O=CHCH2CH=O) has been designated as a potential human carcinogen. A handful of studies suggest that MDA forms in the gas and aerosol phase in the troposphere, potentially contributing to inhalation toxicity, yet it has never been quantified in ambient air. …”
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Microscopic Photosensitization: A New Tool to Investigate the Role of Mitochondria in Cell Death by May-Ghee Lum, Tetsuhiro Minamikawa, Phillip Nagley

“…Using mitochondrially localized CMXRos as a photosensitizer coupled to laser irradiation by confocal laser scanning microscopy, we demonstrate that partial irradiation of about half the mitochondria in human 143B TK– cells induces rapid loss of mitochondrial membrane potential (ΔΨm) in nonirradiated mitochondria. …”
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Overcoming the Constraints of Anti-HIV/CD89 Bispecific Antibodies That Limit Viral Inhibition by Xiaocong Yu, Mark Duval, Melissa Gawron, Marshall R. Posner, Lisa A. Cavacini

“…To this end, bispecific constructs of human antibody F240, reactive with well-conserved gp41 epitope and antibody 14A8, reactive with the IgA receptor (CD89) on effector cells, were constructed. …”
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TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets by Trudy Straetemans, Mandy van Brakel, Sabine van Steenbergen, Marieke Broertjes, Joost Drexhage, Joost Hegmans, Bart N. Lambrecht, Cor Lamers, Pierre van Der Bruggen, Pierre G. Coulie, Reno Debets

“…We identified MC2/A2 and MA3/DP4-specific TCR-Vα3/Vβ28 and TCR-Vα38/Vβ2 chains and validated these TCRs in vitro upon gene transfer into primary human T cells. The MC2 and MA3 TCR were surface-expressed and mediated CD8 T-cell functions towards melanoma cell lines and CD4 T-cell functions towards dendritic cells, respectively. …”
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LPS from P. gingivalis and Hypoxia Increases Oxidative Stress in Periodontal Ligament Fibroblasts and Contributes to Periodontitis by L. Gölz, S. Memmert, B. Rath-Deschner, A. Jäger, T. Appel, G. Baumgarten, W. Götz, S. Frede

“…We hypothesize that hypoxic and inflammatory events induce oxidative stress in the periodontal ligament (PDL) by activating NOX4. Human primary PDL fibroblasts were stimulated with lipopolysaccharide from Porphyromonas gingivalis (LPS-PG), a periodontal pathogen bacterium under normoxic and hypoxic conditions. …”
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Composition and Biological Properties of Agaricus bisporus Fruiting Bodies – a Review by Muszyńska Bożena, Kała Katarzyna, Rojowski Jacek, Grzywacz Agata, Opoka Włodzimierz

“…Studies of tyrosinase isolated from this species show its very high similarity to human tyrosinase. This points directly to the fact that this species could be a rich source of tyrosinase used for medicinal and cosmetics purposes. …”
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Des bois dans les Maisons. Rôles du système social dans la forêt rurale des paysages des Coteaux de Gascogne (Sud-ouest de la France) by Marc Deconchat, Julien Blanco, Émilie Andrieu, Anne Sourdril

“…It focuses on the benefits of closely associating approaches of landscape ecology and human and social sciences to understand the current state and recent history of these woodlots and to help in designing landscape projects adapted to local contexts. …”
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MFGE8, ALB, APOB, APOE, SAA1, A2M, and C3 as Novel Biomarkers for Stress Cardiomyopathy by Xiao-Yu Pan, Zai-Wei Zhang

“…These DEGs were mainly enriched in ECM-receptor interaction, dilated cardiomyopathy (DCM), human papillomavirus infection, and focal adhesion, whereas in GO function classification, they were mainly enriched in the extracellular region, positive regulation of the multicellular organismal process, establishment of localization, and intracellular vesicle. …”
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Methodology for ensuring employee engagement in the context of enterprise digital transformation by I. V. Kablashova, I. V. Logunova, V. N. Rodionova

“…The results of the research can be useful to scientists and practitioners dealing with the problems of human resource management in innovations and digital standards of industrial enterprises implementation.…”
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Increased Kappa/Lambda Hybrid Antibody in Serum Is a Novel Biomarker Related to Disease Activity and Inflammation in Rheumatoid Arthritis by Lang Yi, Mingju Hao, Tian Lu, Guigao Lin, Lida Chen, Ming Gao, Gaowei Fan, Dong Zhang, Guojing Wang, Xin Yang, Yulong Li, Kuo Zhang, Rui Zhang, Yanxi Han, Lunan Wang, Jinming Li

“…The κ/λ hybrid antibodies in normal human serum were reported recently, but their clinical relevance has not yet been explored. …”
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Quantitative Proteomic Analysis of Hepatic Tissue of T2DM Rhesus Macaque by Tingfu Du, Shuaiyao Lu, Qinfang Jiang, Yun Li, Kaili Ma

“…Type 2 diabetes mellitus (T2DM) is a metabolic disorder that severely affects human health, but the pathogenesis of the disease remains unknown. …”
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Spatiotemporal Variation and Abrupt Change Analysis of Temperature from 1960 to 2012 in the Huang-Huai-Hai Plain, China by Yanyu Yin, Hui Liu, Xiangsheng Yi, Weidong Liu

“…The abrupt change time for winter temperature was in the late 1970s, while it was in the late 1980s and early 1990s for spring, autumn, and annual temperature. (4) Macroscopic effects of global and regional climate warming and human activities were probably responsible for the temperature changes. …”
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Successful Integration of Hepatitis C Virus Point-of-Care Tests into the Denver Metro Health Clinic by A. Jewett, A. A. Al-Tayyib, L. Ginnett, B. D. Smith

“…The Centers for Disease Control and Prevention (CDC) recommends testing and linkage to care for persons most likely infected with hepatitis C virus (HCV), including persons with human immunodeficiency virus. We explored facilitators and barriers to integrating HCV point-of-care (POC) testing into standard operations at an urban STD clinic. …”
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