The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking by Daniel P. Neumann, Katherine A. Pillman, B. Kate Dredge, Andrew G. Bert, Caroline A. Phillips, Rachael Lumb, Yesha Ramani, Cameron P. Bracken, Brett G. Hollier, Luke A. Selth, Traude H. Beilharz, Gregory J. Goodall, Philip A. Gregory

“…Using 3’ end anchored RNA sequencing, we mapped the alternative polyadenylation (APA) landscape following Transforming Growth Factor (TGF)-β-mediated induction of EMT in human mammary epithelial cells and found APA generally causes 3’UTR lengthening during this cell state transition. …”
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Toxoplasma gondii in Slaughtered Sheep in High- and Low-Humidity Regions in the South of Iran: Molecular Prevalence and Genotype Identification by Seyedeh Zahra Khademi, Fatemeh Ghaffarifar, Abdolhossein Dalimi, Mohammad Saaid Dayer, Amir Abdoli

“…Toxoplasma gondii is one of the most common meat-born zoonoses that infect all warm-blooded animals and humans. Sheep (Ovis aries) is one of the main reservoirs of T. gondii worldwide, and the infections induce various sequels, such as abortion and stillbirth. …”
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Pathology Survey on a Captive-Bred Colony of the Mexican Goodeid, Nearly Extinct in the Wild, Zoogoneticus tequila (Webb & Miller 1998) by Alessio Arbuatti, Leonardo Della Salda, Mariarita Romanucci

“…Encountered diseases included the following: 7 cases of scoliosis (2 males and 5 females); 2 fish with a similar congenital deviation of ocular axis; 1 adult male with left corneal opacity, presumably of traumatic origin; 1 female fish with a large subocular fluid-filled sac, histologically referable to a lymphatic cyst, similarly to the eye sacs of a Goldfish variety (Carassius auratus) called bubble eye; and 1 female fish with recurrent abdominal distension consequent to distal bowel dilation and thinning, associated with complete mucosal atrophy, and comparable to intestinal pseudo-obstruction syndromes described in humans and various animal species. The absence of infectious or parasitic diseases, as well as the low incidence of diseases potentially related to environmental alterations or nutritional disorders such as spinal deformities, suggests the adequacy of breeding management techniques of Z. tequila for its conservation and reintroduction in to the original habitat in the near future.…”
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Biological properties of Moringa oleifera: A systematic review of the last decade [version 1; peer review: 2 approved, 1 approved with reservations] by Andrea Catalina Gómez, Javier Andrés Soto, C. A. Zuniga-Gonzalez, Karen Shirley Molina, Andrea Natalia Barreto, Maryeli Vásquez

“…Methods In this work, the biological activity of Moringa oleifera in human health was explored through a review of 129 original articles published between 2010 and 2021 related to antitumor activity and its potential uses against chronic and infectious diseases. …”
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Acrylamide Induces Antiapoptotic Autophagy and Apoptosis by Activating PERK Pathway in SH-SY5Y Cells by Yiqi Wang, Ying Liu, Xing Zhang, Yang Jiao, Lian Duan, Ruijie Cheng, Ning Yang, Hong Yan

“…Acrylamide (ACR) is a commonly used organic compound that exhibits evident neurotoxicity in humans. Our previous studies showed that the mechanisms of ACR-caused neurotoxicity included apoptosis, PERK-mediated endoplasmic reticulum stress, and autophagy, but the relationships among them were still unclear. …”
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Asymptomatic cholecystitis and its controversial issues in biliary surgery by Sergey Yurievich Muraviev, Evgeniy Alexandrovich Tarabrin, Alexey Leonidovich Shestakov, Irina Alexandrovna Tarasova, Ivan Alexandrovich Markov, Vadim Sergeevich Razumovsky, Anna Victorovna Ananichuk, Andrey Pavlovich Fabrika, Valeria Alexandrovna Stener, Mehrshad Ebrahimnezhad, Denis Vasilievich Orlushin, Anna Nikolaevna Zavyalova

“…That is why most cases of postcholecystectomy syndrome occur in patients operated on for asymptomatic cholecystitis.The unwillingness to discover the secret of stone formation and asymptomatic cholecystitis in humans when concretions in the gallbladder are detected without reference to surgery, to indicate the trajectory of the examination, leads to a number of tactical errors, preserving the risk of PES, and erasing practical recommendations for the management of such patients. …”
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Peripheral Blood Derived Mononuclear Cells Enhance the Migration and Chondrogenic Differentiation of Multipotent Mesenchymal Stromal Cells by Niina Hopper, John Wardale, Daniel Howard, Roger Brooks, Neil Rushton, Frances Henson

“…The aim of this study was to evaluate the effect of peripheral blood derived mononuclear cell (PBMC) stimulation on mesenchymal stromal cells (MSCs) derived from the infrapatellar fat pad of human OA knee. Cell migration was measured using an xCELLigence electronic migration chamber system in combination with scratch assays. …”
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Automated Indirect Immunofluorescence Evaluation of Antinuclear Autoantibodies on HEp-2 Cells by Jörn Voigt, Christopher Krause, Edda Rohwäder, Sandra Saschenbrecker, Melanie Hahn, Maick Danckwardt, Christian Feirer, Konstantin Ens, Kai Fechner, Erhardt Barth, Thomas Martinetz, Winfried Stöcker

“…Indirect immunofluorescence (IIF) on human epithelial (HEp-2) cells is considered as the gold standard screening method for the detection of antinuclear autoantibodies (ANA). …”
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A hypothetical comparative evaluation system for arctic indoors by Seyed-Amin Tabatabaeifard, Jean-François Lalonde, Marc Hébert, André Potvin, Claude MH. Demers

“…These results should be useful for researchers and practitioners within building sciences, computer vision, and photobiology, showcasing an out-of-the-box approach for categorizing indoor spaces based on standards and human-environmental qualifications.…”
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Levels of PAHs in the Waters, Sediments, and Shrimps of Estero de Urias, an Estuary in Mexico, and Their Toxicological Effects by Foday M. Jaward, Henry A. Alegria, Jose G. Galindo Reyes, Armando Hoare

“…The sources of contamination are closely related to human activities such as domestic and industrial discharge, automobile exhausts, and street runoff. …”
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Synthesis, H2S releasing properties, antiviral and antioxidant activities and acute cardiac effects of nucleoside 5′-dithioacetates by Miklós Bege, Miklós Lovas, Dániel Priksz, Brigitta Bernát, Ilona Bereczki, Rasha Ghanem Kattoub, Richárd Kajtár, Simon Eskeif, Levente Novák, Jan Hodek, Jan Weber, Pál Herczegh, István Lekli, Anikó Borbás

“…The antioxidant activity of 5′-thionucleosides is significantly higher than that of trolox, but lower than that of ascorbic acid, while intact dithioacetates have no remarkable antioxidant effect. In human Calu cells, the guanosine derivative showed a moderate anti-SARS-CoV-2 effect which was also confirmed by virus yield reduction assay. …”
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What Do Gases in the Large Intestine Have to Do with Health? by Klaudia Pawełek, Patrycja Kinga Marta, Filip Maciej Huzarski, Gabriela Monika Ferfecka, Magdalena Rosa-Bończak, Agata Ossolińska, Weronika Kłosowicz, Oliver Carlton, Lucyna Stolarska, Natalia Morawiecka

“… A healthy human gastrointestinal tract contains approximately 200 ml of gas, with an average daily elimination of 600 ml. …”
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Clean Eco-Friendly Cooking Energy as Sustainable Approach and Mitigation to Climate Change: A Case Study of Ankole, Western Uganda. by Kayamba, William Kariiti

“…The main objective was to investigate how traditional cooking fuels have become a health hazard to many mothers and children in Ankole, human activities and rural-urban migration, have caused hiking of prices for fuel for cooking; wetland drainage, bush clearing for farming, charcoal burning, brick making associated with social and economic developments have affected the environment. …”
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Production of Emulsion Paint Using Locally Available Materials. by Turyarugayo, Emmanuel

“…These chemicals are not only expensive to purchase and use but also hazardous to human health and release harmful compounds to our environment after exposure to the chemical paints made on the interior and exterior surfaces where the painting is done. …”
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Clean eco-friendly cooking energy as sustainable approach and mitigation to climate change: A case study of Ankole, Western Uganda by Kayamba William Kariiti

“…The main objective was to investigate how traditional cooking fuels have become a health hazard to many mothers and children in Ankole, human activities and rural-urban migration, have caused hiking of prices for fuel for cooking; wetland drainage, bush clearing for farming, charcoal burning, brick making associated with social and economic developments have affected the environment. …”
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Students’ Daily Attendance Management System. by Komurembe, Phionah, Rukundo, Emmanuel

“…The system provides an intuitive interface for teachers and administrators, enabling real-time tracking and management of student attendance data. By minimizing human errors and ensuring data accuracy, it supports better decision-making in budgeting and resource allocation. …”
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SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

“…Background: The inheritance of the short SLC6A4 allele, encoding the serotonin transporter (SERT) in humans, increases susceptibility to neuropsychiatric and metabolic disorders, with aging and female sex further exacerbating these conditions. …”
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Functional assessment of the glycoproteins of a novel Hendra virus variant reveals contrasting fusogenic capacities of the receptor-binding and fusion glycoproteins by Andrew Z. Ma, Yao Yu Yeo, Jean F. Lee, Colin M. Kim, Shahrzad Ezzatpour, Carolina Menchaca, Viraj Upadhye, Edward J. Annand, John-Sebastian Eden, Raina K. Plowright, Alison J. Peel, David W. Buchholz, Hector C. Aguilar

“…Our in vitro data showed that HeV-g2 glycoproteins induced cell-cell fusion in human cells, shared receptor tropism with HeV-g1, and cross-reacted with antibodies raised against HeV-g1. …”
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Chemical Composition and Larvicidal Activity of Flower Extracts from Clitoria ternatea against Aedes (Diptera: Culicidae) by Darvin R. Ravindran, Madhuri Bharathithasan, Patmani Ramaiah, Mohd Sukhairi Mat Rasat, Dinesh Rajendran, Shakila Srikumar, Intan H. Ishak, Abd Rahman Said, Rajiv Ravi, Mohamad Faiz Mohd Amin

“…Mosquitoes have always been a human health threat; the major global health problems caused by them are malaria, dengue fever, yellow fever, and Zika as well as several other vector-borne outbreaks. …”
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Whole-genome sequencing and phylogenetic analysis of Salmonella isolated from pullets through final raw product in the processing plant of a conventional broiler complex: a longitu... by Yagya Adhikari, Matthew A. Bailey, Steven Kitchens, Pankaj Gaonkar, Luis R. Munoz, Stuart B. Price, Dianna V. Bourassa, Laura Huber, Richard J. Buhr, Kenneth S. Macklin

“…Furthermore, improper cooking or handling of contaminated raw chicken meat and meat products with Salmonella and other zoonotic pathogens can potentially cause foodborne illness in humans.…”
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