DeepCERES: A deep learning method for cerebellar lobule segmentation using ultra-high resolution multimodal MRI by Sergio Morell-Ortega, Marina Ruiz-Perez, Marien Gadea, Roberto Vivo-Hernando, Gregorio Rubio, Fernando Aparici, Maria de la Iglesia-Vaya, Gwenaelle Catheline, Boris Mansencal, Pierrick Coupé, José V. Manjón

“…This paper introduces a novel multimodal and high-resolution human brain cerebellum lobule segmentation method. …”
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POVERTY LEVELS MUST BE REDUCED TO IMPROVE ACCESSIBILITY TO HEALTH SERVICES by Desri Yesi, Ekowati Retnaningsih, Pardomuan Robinson Sihombing, Nuryanto Nuryanto, Irni Novitha

“…Conclusion: Based on the results, policies to improve access to health services, a basic human right, could not be solely achieved by the health sector. …”
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Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals by Gerardo Claudio Glikin, Liliana María Elena Finocchiaro

“…The encouraging outcomes obtained in companion animals support their ready application in veterinary clinical oncology and serve as preclinical proof of concept and safety assay for future human gene therapy trials.…”
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A Novel Protective Framework for Defeating HTTP-Based Denial of Service and Distributed Denial of Service Attacks by Mohammed A. Saleh, Azizah Abdul Manaf

“…Secondly, the service traceback oriented architecture (STBOA) scheme is to validate whether the incoming request is launched by a human or by an automated tool. Then, it traces back the true attacking IP source. …”
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Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response by Agnieszka Krupa, Marek Fol, Bozena R. Dziadek, Ewa Kepka, Dominika Wojciechowska, Anna Brzostek, Agnieszka Torzewska, Jaroslaw Dziadek, Robert P. Baughman, David Griffith, Anna K. Kurdowska

“…Interleukin-8 (IL-8) has been implicated in the pathogenesis of several human respiratory diseases, including tuberculosis (TB). …”
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Assessment of Antioxidant and Cytotoxicity Activities of Saponin and Crude Extracts of Chlorophytum borivilianum by Mehdi Farshad Ashraf, Maheran Abd Aziz, Johnson Stanslas, Ismanizan Ismail, Mihdzar Abdul Kadir

“…Cytotoxicity evaluation of crude extract and total saponin fraction against MCF-7, PC3, and HCT-116 cancer cell lines using 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyltetrazolium bromide (MTT) cell viability assay indicated a higher cytotoxicity activity of the crude extract than the total saponin fraction on all cell lines, being most effective and selective on MCF-7 human breast cancer cell line.…”
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Metabolism of Mycotoxins, Intracellular Functions of Vitamin B12, and Neurological Manifestations in Patients with Chronic Toxigenic Mold Exposures. A Review by Ebere C. Anyanwu, Mohammed Morad, Andrew W. Campbell

“…Since patients with chronic exposures to toxigenic molds manifest vitamin B12 deficiencies, the role of mycotoxins in vitamin B12 metabolism is assessed, and since vitamin B12 plays important biochemical roles in one-carbon metabolism, the synergistic effects with mycotoxins on humans are reviewed. An outline of the proposed mechanism by which mycotoxins disrupt or interfere with the normal functions of vitamin B12 on one-carbon metabolism is proposed. …”
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Cumulative Risk Assessment Toolbox: Methods and Approaches for the Practitioner by Margaret M. MacDonell, Lynne A. Haroun, Linda K. Teuschler, Glenn E. Rice, Richard C. Hertzberg, James P. Butler, Young-Soo Chang, Shanna L. Clark, Alan P. Johns, Camarie S. Perry, Shannon S. Garcia, John H. Jacobi, Marcienne A. Scofield

“…Resources are organized according to the main elements of the assessment process: (1) planning, scoping, and problem formulation; (2) environmental fate and transport; (3) exposure analysis extending to human factors; (4) toxicity analysis; and (5) risk and uncertainty characterization, including presentation of results. …”
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The Value of Routine Polymerase Chain Reaction Analysis of Intraocular Fluid Specimens in the Diagnosis of Infectious Posterior Uveitis by Marius A. Scheepers, Karin A. Lecuona, Graeme Rogers, Catey Bunce, Craig Corcoran, Michel Michaelides

“…To assess the value of routine polymerase chain reaction (PCR) analysis on intraocular fluid from patients presenting with a first episode of suspected active infectious posterior uveitis in a population with a high prevalence of human immunodeficiency virus infection. Design. Retrospective, interventional case series. …”
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Relations entre l’estime de soi et l’état de santé « objectif » des aînés by Enguerran Macia, Gilles Boëtsch, Nicole Chapuis-Lucciani

“…In spite of several studies on self-esteem covering the human life-span, the relation between self-esteem, aging and health remains incompletely explored, particularly in the French population.The objective of this study is twofold: (1) to assess the relation between self-esteem and socio-demographic factors, notably age, among older French adults, and (2) if, as is presumed, advancing age is associated with lower self-esteem, to test the mediating effect of chronic diseases and physical incapacities on the relation between age and negative self-esteem.For this, 400 older adults living in Marseille, aged from 60 to 92, were individually interviewed (average duration: 1 h 30).In this sample, age, place of residence and educational level were associated with self-esteem. …”
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Empathic love therapy for adolescents living with HIV in Surabaya, Indonesia by Erika Martining Wardani, Riezky Faisal Nugroho, Siti Nurjanah, Syiddatul Budury, Iis Noventi

“…Introduction Adolescents with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) do not only experience physical pain. …”
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Eliciting Emotions: Investigating the Use of Generative AI and Facial Muscle Activation in Children’s Emotional Recognition by Manuel A. Solis-Arrazola, Raul E. Sanchez-Yanez, Ana M. S. Gonzalez-Acosta, Carlos H. Garcia-Capulin, Horacio Rostro-Gonzalez

“…The aim is to determine if AI can realistically generate and recognize emotions similar to human experiences. The study involves generating a database of 280 images (40 per emotion) of children expressing various emotions. …”
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Thiamine and Thiamine Pyrophosphate as Non-Competitive Inhibitors of Acetylcholinesterase—Experimental and Theoretical Investigations by Łukasz Szeleszczuk, Dariusz Maciej Pisklak, Błażej Grodner

“…Vitamin B₁ (thiamine) plays an important role in human metabolism. It is essential for the proper growth and development of the body and has a positive effect on the functioning of the digestive, cardiovascular, and nervous systems. …”
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Roles of Whole-Genome Sequencing in Determining Transmission and Risk Factors Associated with Carbapenem-Resistant Organisms at a Vietnam HealthCare Center of Orphan Children by Van Kim Nguyen, Pirom Noisumdaeng, Katiya Ivanovitch, Eugene Athan, Larry Croft, Phuong Toai Nguyen, Huu Phuc Pham Nguyen

“…At this center, we performed a cross-sectional study and collected fecal samples from humans (20 healthcare workers (HCWs) and 67 residents) and 175 environmental samples, with rectal and environment swabs, as data for this study, from September 2022 to December 2022. …”
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Essentials of a Robust Deep Learning System for Diabetic Retinopathy Screening: A Systematic Literature Review by Aan Chu, David Squirrell, Andelka M. Phillips, Ehsan Vaghefi

“…An ideal deep learning algorithm should be clinic-, clinician-, and camera-agnostic; complying with the local regulation for data sovereignty, storage, privacy, and reporting; whilst requiring minimum human input.…”
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Evaluation of Genotype Diversity in Oat Germplasm and Definition of Ideotypes Adapted to the Mediterranean Environment by Anna Iannucci, Pasquale Codianni, Luigi Cattivelli

“…Oat (Avena sativa L.) is a cereal species widely used for human food and livestock feed. It is rich in primary metabolites (e.g., protein, carbohydrate, and fibre) as well as in many secondary compounds (e.g., fructo-oligosaccharides). …”
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Prospective de novo drug design with deep interactome learning by Kenneth Atz, Leandro Cotos, Clemens Isert, Maria Håkansson, Dorota Focht, Mattis Hilleke, David F. Nippa, Michael Iff, Jann Ledergerber, Carl C. G. Schiebroek, Valentina Romeo, Jan A. Hiss, Daniel Merk, Petra Schneider, Bernd Kuhn, Uwe Grether, Gisbert Schneider

“…In order to proactively evaluate the deep interactome learning framework for protein structure-based drug design, potential new ligands targeting the binding site of the human peroxisome proliferator-activated receptor (PPAR) subtype gamma are generated. …”
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E-Bike Injuries: Experience from an Urban Emergency Department—A Retrospective Study from Switzerland by Sylvana Papoutsi, Luca Martinolli, Christian Tasso Braun, Aristomenis K. Exadaktylos

“…This continuous and rapid transition from human-powered bicycles to an electric bicycle technology may indicate the increasing demand for low-cost transportation technology in combination with a healthy lifestyle. …”
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A collaborative management model as an effort for the conservation of native plants of Java’s mountains in Mount Merbabu National Park by Gunawati Dewi, Sulaksono Nurpana, Ibrahim Mohd Hairy

“…The preservation of these native plants is threatened by anthropogenic activities in the surrounding area, including forest fires, highintensity human activities, illegal actions, and excessive exploitation. …”
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Temperature Depended Role of Shigella flexneri Invasion Plasmid on the Interaction with Acanthamoeba castellanii by Amir Saeed, David Johansson, Gunnar Sandström, Hadi Abd

“…Shigella flexneri is a Gram-negative bacterium causing the diarrhoeal disease shigellosis in humans. The virulence genes required for invasion are clustered on a large 220 kb plasmid encoding type three secretion system (TTSS) apparatus and virulence factors such as adhesions and invasion plasmid antigens (Ipa). …”
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