New insights into Notch signaling as a crucial pathway of pancreatic cancer stem cell behavior by chrysin-polylactic acid-based nanocomposite by Eman M. Ragab, Doaa M. El Gamal, Fares F. El-najjar, Hager A. Elkomy, Mahmoud A. Ragab, Mariam A. Elantary, Omar M. Basyouni, Sherif M. Moustafa, Shimaa A. EL-Naggar, Abeer S. Elsherbiny

“…A population of pancreatic cancer stem cells with aberrantly active developmental signaling pathways has been identified in recent studies of human pancreatic tumors. Among these Notch signaling pathway has been identified as a key regulator of CSCs self-renewal, making it an attractive target for therapeutic intervention. …”
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Supervised and Self-Supervised Learning for Assembly Line Action Recognition by Christopher Indris, Fady Ibrahim, Hatem Ibrahem, Götz Bramesfeld, Jie Huo, Hafiz Mughees Ahmad, Syed Khizer Hayat, Guanghui Wang

“…The safety and efficiency of assembly lines are critical to manufacturing, but human supervisors cannot oversee all activities simultaneously. …”
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R-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania by Jeziel D. Damasceno, Emma M. Briggs, Marija Krasilnikova, Catarina A. Marques, Craig Lapsley, Richard McCulloch

“…Abstract Genomes in eukaryotes normally undergo DNA replication in a choreographed temporal order, resulting in early and late replicating chromosome compartments. Leishmania, a human protozoan parasite, displays an unconventional DNA replication program in which the timing of DNA replication completion is chromosome size-dependent: larger chromosomes complete replication later then smaller ones. …”
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A data-driven methodology for the classification of different liquids in artificial taste recognition applications with a pulse voltammetric electronic tongue by Jersson X Leon-Medina, Leydi J Cardenas-Flechas, Diego A Tibaduiza

“…Electronic tongue-type sensor arrays are devices used to determine the quality of substances and seek to imitate the main components of the human sense of taste. For this purpose, an electronic tongue-based system makes use of sensors, data acquisition systems, and a pattern recognition system. …”
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Prevalence of Blood-Borne Viruses in Health Care Workers of a Northern District in Pakistan: Risk Factors and Preventive Behaviors by Muhammad Zuhaib Khan, Shahab Saqib, Sayed Irtiza Hussain Shah Gardyzi, Javaria Qazi

“…There is also a potential threat of human immunodeficiency virus (HIV) spread in the country. …”
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Diversity and bioindicators of natural enemies in organic paddy fields implementing habitat modification by Setyadin Yuris, Leksono Amin Setyo, Tarno Hagus

“…Indonesian rice farming relies heavily on intensive systems, adversely affecting soil quality, human health, and non-target organisms. Organic systems are a viable alternative characterized by organic fertilizers and biopesticides, avoiding genetically modified microorganisms and promoting biodiversity. …”
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On the Design and Performance Analysis of Flexible Planar Monopole Ultra-Wideband Antennas for Wearable Wireless Applications by Deepa Thangarasu, Rama Rao Thipparaju, Sandeep Kumar Palaniswamy, Malathi Kanagasabai, Mohammed Gulam Nabi Alsath, Devisowjanya Potti, Sachin Kumar

“…The antenna conformability is measured by placing the fabricated antennas on various curved and nonplanar parts of the human body. The aforementioned antennas offer better flexibility for different bent conditions. …”
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Biomonitoring of radioactive contamination using benthic invertebrate communities in Manzala Lake, Egypt by Imam Noha, Bendary Reda E.

“…Manzala Lake, the largest in Egypt’s Nile Delta, has significant human activity. The Lake’s ecological condition has recently been impacted by a significant increase in agricultural, industrial, and urban wastewater discharge. …”
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Socioeconomic Characteristics Influencing Level of Awareness of Aflatoxin Contamination of Feeds among Livestock Farmers in Meru District of Tanzania by E. M. Ayo, A. Matemu, G. H. Laswai, M. E. Kimanya

“…Aflatoxins occurrence in feeds challenges human and animal health. Farmers’ awareness status of these toxins has an effect on their level of exposure. …”
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Quo Vadis PCA? A Review on Current Concepts, Economic Considerations, Patient-Related Aspects, and Future Development with respect to Patient-Controlled Analgesia by S. Nardi-Hiebl, L. H. J. Eberhart, M. Gehling, T. Koch, T. Schlesinger, P. Kranke

“…New PCA technology can support the implementation of efficient processes to reduce workload and human errors; however, these new products come with a cost, which is not necessarily reflected through beneficial budget impact or significant improvements in patient outcome. …”
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Intranasally administrated fusion-inhibitory lipopeptides block SARS-CoV-2 infection in mice and enable long-term protective immunity by Said Mougari, Valérie Favède, Camilla Predella, Olivier Reynard, Stephanie Durand, Magalie Mazelier, Edoardo Pizzioli, Didier Decimo, Francesca T. Bovier, Lauren M. Lapsley, Candace Castagna, Nicole A. P. Lieberman, Guillaume Noel, Cyrille Mathieu, Bernard Malissen, Thomas Briese, Alexander L. Greninger, Christopher A. Alabi, N. Valerio Dorrello, Stéphane Marot, Anne-Geneviève Marcelin, Ana Zarubica, Anne Moscona, Matteo Porotto, Branka Horvat

“…Abstract We have assessed antiviral activity and induction of protective immunity of fusion-inhibitory lipopeptides derived from the C-terminal heptad-repeat domain of SARS-CoV-2 spike glycoprotein in transgenic mice expressing human ACE2 (K18-hACE2). The lipopeptides block SARS-CoV-2 infection in cell lines and lung-derived organotypic cultures. …”
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Transcranial Magnetic Stimulation as a Potential Biomarker in Multiple Sclerosis: A Systematic Review with Recommendations for Future Research by Nicholas J. Snow, Katie P. Wadden, Arthur R. Chaves, Michelle Ploughman

“…Transcranial magnetic stimulation (TMS) is a noninvasive method used to study the human motor system, which has shown potential in MS research. …”
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RECQ4-MUS81 interaction contributes to telomere maintenance with implications to Rothmund-Thomson syndrome by Raghib Ashraf, Hana Polasek-Sedlackova, Victoria Marini, Jana Prochazkova, Zdenka Hasanova, Magdalena Zacpalova, Michala Boudova, Lumir Krejci

“…This underscores the importance of RECQ4-MUS81 in safeguarding genome integrity and suggests potential implications for human disease. Our findings demonstrate the RECQ4-MUS81 interaction as a key mechanism in alleviating replication stress at hard-to-replicate regions and highlight its relevance in pathological conditions such as RTS.…”
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The Role of Mannose-Binding Lectin in Severe Sepsis and Septic Shock by Gennaro De Pascale, Salvatore Lucio Cutuli, Mariano Alberto Pennisi, Massimo Antonelli

“…Mannose-binding lectin (MBL) is a serum protein that recognizes a wide range of pathogenic microorganisms and activates complement cascade via the antibody-independent pathway. More than 30% of humans harbor mutations in MBL gene (MBL2) resulting in reduced plasmatic levels and activity. …”
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Sensorimotor Cortical Neuroplasticity in the Early Stage of Bell’s Palsy by Wenwen Song, Minhui Dai, Lihua Xuan, Zhijian Cao, Sisi Zhou, Courtney Lang, Kun Lv, Maosheng Xu, Jian Kong

“…Neuroplasticity is a common phenomenon in the human brain following nerve injury. It is defined as the brain’s ability to reorganize by creating new neural pathways in order to adapt to change. …”
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Impact of Aqueous Extract Artemisia Herba-Alba Leaves as a Green Inhibitor against Acid Activation of 2024 Aluminum Alloy by Nacer Hechiche, Gérald Culioli, Abdelaziz Kadri, Dalila Boughrara, Amar Saal, F. Xavier Perrin

“…This work is part of the development of new bio-sourced corrosion inhibitors from an abundant resource that can replace conventional synthetic inhibitors that are harmful to both human health and the environment. The corrosion inhibition performance of an aqueous extract of Artemisia herba-alba on the corrosion of 2024 aluminum alloy in a 1 M hydrochloric acid solution is investigated by weight loss method, electrochemical (linear polarization, potentiodynamic polarization, and electrochemical impedance spectroscopy) and SEM techniques. …”
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Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic Mice by Yoo-Ri Chung, Jeong A. Choi, Jae-Young Koh, Young Hee Yoon

“…Additionally, induction of ER stress and the unfolded protein response (UPR) were assessed in diabetic mice and human retinal pericytes exposed to advanced glycation end products (AGE) or modified low-density lipoprotein (mLDL). …”
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The Impact of Adequate Selenium Intake on Severity Symptoms and Quality of Life among People with Allergic Rhinitis by Thanyapron Tiyawisutsri, Napassorn Suwanpanyakul, Weeraya Kongkasri, Kamonwan Thongsri, Roger Timothy Callaghan, Alongkote Singhato

“…Background: Selenium (Se) deficiency leads to impairment of human immune function. Allergic Rhinitis (AR) is one of the most common immune-related diseases that affects the quality of life among patients. …”
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Assembly of Genetically Engineered Ionizable Protein Nanocage-based Nanozymes for Intracellular Superoxide Scavenging by Qiqi Liu, Zhanxia Gao, Xiangyun Zhang, Qiannan Duan, Yue Zhang, Adam C. Midgley, Li Jiao, Ruming Liu, Mingsheng Zhu, Deling Kong, Jie Zhuang, Xinglu Huang

“…Specifically, ionizable repeated Histidine-Histidine-Glutamic acid (9H2E) sequences are genetically incorporated into the outer surface of human heavy chain FTn, followed by the assembly of various chain-like nanostructures via a two-armed polyethylene glycol (PEG). …”
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Analysis of Seed Vigor Using the Biospeckle Laser Technique by Roberto A. Braga, José Luís Contado, Karina Renostro Ducatti, Edvaldo A. Amaral da Silva

“…However, monitoring seed vigor over time poses a significant challenge for the seed industry, as traditional methods are time-consuming and heavily reliant on subjective human judgment. Concerning these limitations, optical-based techniques have emerged as promising alternatives. …”
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