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  1. 1761
  2. 1762

    Full-length inhibitor protein is the most effective to perturb human dUTPase activity by Bianka Kőhegyi, Zoé S. Tóth, Enikő Gál, Máté Laczkovich, András Benedek, Beáta G. Vértessy, Kinga Nyíri

    Published 2025-02-01
    “…The effect of StlNT and a peptide derived from the full-length inhibitor on the activity of the human dUTPase was also tested. We showed that the C-terminal part of the Stl protein omitted from the crystal structure has an important role in the enzyme inhibition as the full-length Stl is needed to exert maximal inhibition on the human dUTPase.…”
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  3. 1763

    Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells by Daniel Alvarez-Berdugo, Marcel Jiménez, Pere Clavé, Laia Rofes

    Published 2014-01-01
    “…We aimed to explore the pharmacodynamics of the TRPV1 agonists, capsaicin, natural capsaicinoids, and piperine in an in vitro bioassay using human PC-3 cells and to examine desensitization and the effect of the specific antagonist SB366791. …”
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  4. 1764
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  6. 1766

    An Emerging Pulmonary Haemorrhagic Syndrome in Dogs: Similar to the Human Leptospiral Pulmonary Haemorrhagic Syndrome? by R. Klopfleisch, B. Kohn, S. Plog, C. Weingart, K. Nöckler, A. Mayer-Scholl, A. D. Gruber

    Published 2010-01-01
    “…Severe pulmonary haemorrhage is a rare necropsy finding in dogs but the leptospiral pulmonary haemorrhagic syndrome (LPHS) is a well recognized disease in humans. Here we report a pulmonary haemorrhagic syndrome in dogs that closely resembles the human disease. …”
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  7. 1767
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    Plant miRNAs for Improved Gene Regulation in a Wide Range of Human Cancers by Maksym Zoziuk, Vittorio Colizzi, Pavlo Krysenko, Maurizio Mattei, Roberta Bernardini, Fabio Massimo Zanzotto, Stefano Marini, Dmitri Koroliouk

    Published 2025-01-01
    “…Based on the broad database of human miRNA expression for all cancer types, we grade human miRNAs by their expression level. …”
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  9. 1769
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    Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1 by Ryo Kubota, Michael J. Reid, Kuo Lee Lieu, Mark Orme, Christine Diamond, Niklas Tulberg, Susan H. Henry

    Published 2020-01-01
    “…The larger hydrophobic compounds from Astellas (compound 35c) and Boehringer Ingelheim (PXS-4728A) were hypothesized to have higher binding affinity for human VAP-1 compared to rodent VAP-1 since the channel in human VAP-1 is larger and more hydrophobic than that in rodent VAP-1. …”
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  11. 1771
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    Avatars and humans may not elicit the same accent-related biases in mock courtroom research by Lara A. Frumkin, Anna Stone, Mary Jane Spiller

    Published 2025-02-01
    “…A three-way interaction showed the Lebanese human non-standard accented witness was rated more poorly than her standard-accented counterpart, her avatar counterpart, and the Mexican and German human non-standard accented witnesses.DiscussionFindings reveal that avatar witnesses cannot yet reliably replace their human counterparts. …”
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  14. 1774

    RELAP5/MOD3.3 Best Estimate Analyses for Human Reliability Analysis by Andrej Prošek, Borut Mavko

    Published 2010-01-01
    “…The purpose of the study was to estimate the operator action success criteria time windows in scenarios in which the human actions are supplement to safety systems actuations, needed for updated human reliability analysis (HRA). …”
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  15. 1775

    High Association between Human Circulating MicroRNA-497 and Acute Myocardial Infarction by Zhenci Li, Jing Lu, Yi Luo, Shaonan Li, Minsheng Chen

    Published 2014-01-01
    “…In conclusion, circulating miR-497 might be a promising biomarker for AMI identification and there was high association between human miR-497 and acute myocardial infarction.…”
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  16. 1776

    Role of the Microenvironment in Mesenchymal Stem Cell-Based Strategies for Treating Human Liver Diseases by Shan-jing Xu, Li-ping Ye, Wei Wang, Ya-hong Chen, Jian Dong, Xin-li Mao, Shao-wei Li

    Published 2021-01-01
    “…Liver disease is a severe health problem that endangers human health worldwide. Mesenchymal stem cell (MSC) therapy is a novel treatment for patients with different liver diseases due to its vast expansion potential and distinctive immunomodulatory properties. …”
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  17. 1777

    The Food Safety Modernization Act of 2011: Final Rule for Preventive Controls for Human Food by Jessica Lepper, Soohyoun Ahn, Keith R. Schneider, Michelle Danyluk, Renée M. Goodrich Schneider

    Published 2018-01-01
    “…It is intended to provide an overview of the final Preventive Controls for Human Food (PCHF) rule. Written by Jessica A. Lepper, Soohyoun Ahn, Keith R. …”
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    Upper-Limb Muscle Synergy Features in Human-Robot Interaction with Circle-Drawing Movements by Cheng Wang, Shutao Zhang, Jingyan Hu, Zhejing Huang, Changcheng Shi

    Published 2021-01-01
    “…However, the muscle synergies characterized by multiple surface electromyographic (sEMG) signals in upper limbs during human-robot interaction (HRI) with circle-drawing movements are rarely investigated. …”
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