The Modulation of PPARγ1 and PPARγ2 mRNA Expression by Ciglitazone in CD3/CD28-Activated Naïve and Memory CD4+ T Cells by Mohd Nor Norazmi, Rafeezul Mohamed, Asma Abdullah Nurul, Nik Soriani Yaacob

“…Given their roles in immune regulation, the expression of the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) 1 and 2 isoforms was investigated in human naïve (CD45RA+) and memory (CD45RO+) CD4+ T cells. …”
Get full text

c-Jun-N-Terminal Kinase Signaling Is Involved in Cyclosporine-Induced Epithelial Phenotypic Changes by Nicolas Pallet, Eric Thervet, Dany Anglicheau

“…In primary cultures of human renal epithelial cells, CsA activates JNK signaling, and the treatment with a JNK inhibitor reduces the occurrence of cell shape changes, E-cadherin downregulation, cell migration, and Snail-1 expression. …”
Get full text

Exploration of the Role of Cyclophilins in Established Hepatitis B and C Infections by Jennifer Molle, Sarah Duponchel, Jennifer Rieusset, Michel Ovize, Alexander V. Ivanov, Fabien Zoulim, Birke Bartosch

“…We show, furthermore, that CypA silencing has a modest but reproducible impact on persistent HBV infections in cultured human hepatocytes.…”
Get full text

Major Depressive Disorder and Measures of Cellular Aging: An Integrative Review by Patricia Anne Kinser, Debra E. Lyon

“…This review integrates findings from eleven human studies which evaluated telomere length and telomerase activity, in order to synthesize the state of the current science and to inform the development of new knowledge and enhance nursing research of depression using appropriate biobehavioral measures. …”
Get full text

Islam and Scholarship Tradition: Historical Trajectories and Future Challenges of Modernity by Mohammad Fadel

“…These social, economic, and political phenomena not only bring opportunities for a human betterment but also challenges to Islamic tradition and community. …”
Get full text

Imagining alternative futures through the lens of food in the Afghan and Tajik Pamir mountains by Frederik J.W. Van Oudenhoven, L. Jamila Haider

“…Using Felix Guattari’s concept of the ‘three ecologies’, we apply these perspectives to an analysis of the three spheres in which development agencies in the region are active : landscape and agriculture, social (economic) relationships, and the human subjectivity of memories, identity and imagination. …”
Get full text

Evaluation of Mechanochemically Prepared CePO₄∙H₂O Nanoparticles as UV Filter for Photoprotective Formulations by Stanislav Kurajica, Filip Brleković, Sabina Keser, Goran Dražić, Katarina Mužina, Vanesa Mihajlović

“…The photocatalytic activity in the Castor oil degradation process and the cytotoxicity for human skin cells were determined and compared to commercial TiO₂ nanoparticles, with rhabdophane nanoparticles exhibiting superior properties. …”
Get full text

Blood Glucose Control Using a Novel Continuous Blood Glucose Monitor and Repetitive Intravenous Insulin Boluses: Exploiting Natural Insulin Pulsatility as a Principle for a Future... by Nils K. Skjaervold, Dan Östling, Dag R. Hjelme, Olav Spigset, Oddveig Lyng, Petter Aadahl

“…The main obstacles were the drift of the IvS-1 sensor and problems with the calibration procedure, which calls for an improvement in the sensor stability before this method can be applied fully in new studies in animals and humans.…”
Get full text

Escherichia coli Strains Isolated from the Uteri Horn, Mouth, and Rectum of Bitches Suffering from Pyometra: Virulence Factors, Antimicrobial Susceptibilities, and Clonal Relations... by Juliana M. A. Agostinho, Andressa de Souza, Ruben P. Schocken-Iturrino, Lívia G. Beraldo, Clarissa A. Borges, Fernando A. Ávila, José M. Marin

“…Using the genotypic methods some isolates from uteri, pus, and saliva of the same bitch proved to have identical DNA profiles which is a reason for concern due to the close relationship between household pets and humans.…”
Get full text

Removing Heavy Metals from the Soil with Phytoremediation by Mustafa Aybar, Ayla Bilgin, Bülent Sağlam

“…Environmental pollution is one of the most critical factors adversely affecting human health. Improvement in living standards, the rapid increase of urban populations, and widespread industrial production, all result in the generation of huge amounts of environment-polluting waste. …”
Get full text

Preventing Foodborne Illness: Yersiniosis by Christopher R. Pabst, Jaysankar De, Aswathy Sreedharan, Correy Jones, Keith R. Schneider

“…Schneider and published by the UF/IFAS Food Science and Human Nutrition Department, also describes long-term effects and complications of yersiniosis, members of the population most at risk, and prevention methods. …”
Get full text

Animal Models of Diabetic Retinopathy: Summary and Comparison by Angela Ka Wai Lai, Amy C. Y. Lo

“…Until now, there is no single model that displays all the clinical features of DR as seen in human. Yet, with the understanding of the pathological findings in these animal models, researchers can select the most suitable models for mechanistic studies or drug screening.…”
Get full text

Protective Immunity against SARS Subunit Vaccine Candidates Based on Spike Protein: Lessons for Coronavirus Vaccine Development by Atin Khalaj-Hedayati

“…Although several attempts have been made to develop vaccines against human coronavirus infections since the emergence of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) in 2003, there is no available licensed vaccine yet. …”
Get full text

Economic Aspects of Slavery in the Triangular Trade in the Early Modern Period by Igor JOSIPOVIĆ, Marko VUJEVA

“…Slavery has existed since the beginning of human civilisation. However, there was a great upsurge in slavery during the early modern period and the Age of Discovery, when it gained enormous popularity and took new forms. …”
Get full text

The protective role of carotenoids in chronic obstructive pulmonary disease: A systematic review and Meta-analysis of observational studies by Jing Sui, Wenbin Shen, Yanni Zhang, Jiarui Liang, Hui Xia, Guiju Sun

“…Both observational studies conducted in human populations were included, and association between level of carotenoids intake/blood and COPD. …”
Get full text

EMPOWERING COMMUNITIES FOR SUSTAINABLE TRANSITION: INTEGRATING TOURISM WITH ECONOMIC AND SOCIODEMOGRAPHIC DYNAMICS IN POST-MINING STRATEGIES by Agung Dwi SUTRISNO, Chun-Hung LEE, Sapta SUHARDONO, I Wayan Koko SURYAWAN

“…The findings underscore the importance of investing in human capital, primarily through targeted educational programs to enhance skills necessary for environmental stewardship and tourism-related activities. …”
Get full text

Photoreceptor metabolic window unveils eye–body interactions by Shaopeng Yang, Zhuoyao Xin, Weijing Cheng, Pingting Zhong, Riqian Liu, Ziyu Zhu, Lisa Zhuoting Zhu, Xianwen Shang, Shida Chen, Wenyong Huang, Lei Zhang, Wei Wang

“…Our work, replicated across cohorts of diverse ethnicities, reveals the potential of photoreceptors to inform systemic health and advance a multisystem perspective on human health by revealing eye–body connections and shared metabolic influences.…”
Get full text

Establishing Lot Size through Sanitation Clean Breaks in Produce Packing Facilities by Benjamin Chapman, Michelle D. Danyluk

“…Danyluk and published by the UF Department of Food Science and Human Nutrition, August 2013. http://edis.ifas.ufl.edu/fs234 …”
Get full text

Something old, something new: preliminary findings from an exploratory study about people's information habits and information grounds by Fisher Naumer, Durrance, Stromsky, Christianson

“…</b> A telephone survey of 612 urban-rural residents was conducted regarding their needs for health and human services in partnership with the United Way of America. …”
Get full text

ALIGNING PRAXIS OF FAITH AND THEOLOGICAL THEORY IN THEOLOGICAL EDUCATION THROUGH AN EVALUATION OF CHRISTIANITY IN SOUTH AFRICA by E. Oliver

“…Just as the Fourth Industrial Revolution blurs the distinctive lines between physical, digital, and biological, so should the separated boxes of personal faith, institutionalised religion, and spirituality be wiped out. Human self-awareness helps us know ourselves and improve our ability to glorify God, while the Communication Revolution empowers Christians to spread the gospel globally. …”
Get full text