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16381
Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets
Published 2025-01-01“…Abstract T cells mediate pathogenesis of several autoimmune disorders by recognizing self-epitopes presented on Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) complex. The majority of autoantigens presented to T cells in various autoimmune disorders are not known, which has impeded autoantigen identification. …”
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16382
Expanding horizon of invasive alien plants under the interacting effects of global climate change: Multifaceted impacts and management prospects
Published 2025-07-01“…Consequently, IAP-climate change can influence ecological economics, livelihood, and human well-being. Implementation of species distribution model (SDM) into management and mitigation strategies is required to control IAP along with the present and future climate change scenarios.…”
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16383
UNVEILING THE ROOTS OF ENDURING COMMUNAL CONFLICTS IN NIGERIA: INDIGENE-SETTLER RIVALRY AND THE PATH FORWARD
Published 2024-06-01“…These conflicts have inflicted significant harm, including widespread community devastation, loss of life, displacement of millions, and severe human rights violations, particularly impacting vulnerable populations like women and children. …”
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16384
Investigation of Viral, Bacterial and Parasitic Zoonotic Diseases in Rodents in Turkey
Published 2024-11-01“…The extent of the distribution of the infections, alternative hosts and the consequences of human exposure needs to be clarified through further studies.…”
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16385
Down-Regulation of Tristetraprolin Expression Results in Enhanced IL-12 and MIP-2 Production and Reduced MIP-3α Synthesis in Activated Macrophages
Published 2006-01-01“…Cytokines IL-6, IL-12, TNF-α, and MIP-2 (a homologue to human IL-8) were expressed at higher levels whereas MIP-3α was produced at lower levels in LPS-treated shTTP cells than in control cells suggesting that the expression of these cytokines is regulated by TTP. …”
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16386
Characterization of Zebrafish von Willebrand Factor Reveals Conservation of Domain Structure, Multimerization, and Intracellular Storage
Published 2012-01-01“…von Willebrand disease (VWD) is the most common inherited human bleeding disorder and is caused by quantitative or qualitative defects in von Willebrand factor (VWF). …”
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16387
Equine Infectious Anemia Virus Cellular Partners Along the Viral Cycle
Published 2024-12-01“…Equine infectious anemia virus (EIAV) is the simplest described <i>lentivirus</i> within the <i>Retroviridae</i> family, related to the human immunodeficiency viruses (HIV-1 and HIV-2). …”
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16388
An Optimized Protocol for Simultaneous Propagation of Patient-derived Organoids and Matching CAFs
Published 2025-01-01“…Existing models are limited to a few HR+ cell lines, organoid models, and patient-derived xenograft models, all lacking components of the human tumor microenvironment. Furthermore, the low take rate and loss of estrogen receptor (ER) expression in patient-derived organoids (PDOs) has been challenging. …”
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16389
Outcome of Allogeneic Adult Stem Cell Therapy in Dogs Suffering from Osteoarthritis and Other Joint Defects
Published 2018-01-01“…Osteoarthritis is a common condition that causes joint pain and stiffness that affects both humans and dogs. In Australia, allogeneic canine adipose-derived mesenchymal stem cells for therapy have been commercially available since 2010. …”
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16390
Modeling and simulation for toxicity assessment
Published 2017-05-01“…The effect of various toxicants on growth/death and morphology of human cells is investigated using the xCELLigence Real-Time Cell Analysis High Troughput in vitro assay. …”
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16391
Readiness for Perception and Action: Towards a More Mechanistic Understanding of Phasic Alertness
Published 2025-01-01“…Human survival requires prompt perception and action to address relevant events in the environment. …”
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16392
Polar stations as testing platforms for space analogue simulations – Case study for Polish potential
Published 2025-12-01“…The extensive experience of Polish polar researchers provides a relevant background for crew selection and support in conducting physiological and psychological studies on humans. In conclusion, polar stations can function as simulation laboratories for the new era of space exploration.…”
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16393
Characterization of Potential Virulence Factors of Vibrio mimicus Isolated from Fishery Products and Water
Published 2021-01-01“…Vibrio mimicus is a Gram-negative bacterium that is closely related to V. cholerae and causes gastroenteritis in humans due to contaminated fish consumption and seafood. …”
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16394
Amniotic Fluid Stem Cells: Future Perspectives
Published 2012-01-01“…The existence of stem cells in human amniotic fluid was reported for the first time almost ten years ago. …”
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16395
Preparación de alimentos en puré
Published 2014-03-01“…Lepore, and published by the UF Department of Food Science and Human Nutrition, February 2014. FSHN12-12s/FS246: Preparación de alimentos en puré (ufl.edu) …”
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16396
Exploring Host Genetic Polymorphisms Involved in SARS-CoV Infection Outcomes: Implications for Personalized Medicine in COVID-19
Published 2020-01-01“…To systematically explore genetic polymorphisms associated with the clinical outcomes in SARS-CoV infection in humans. Methods. This comprehensive literature search comprised available English papers published in PubMed/Medline and SCOPUS databases following the PRISMA-P guidelines and PICO/AXIS criteria. …”
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16397
Biology Learners’ Conception of Ecology of a Wetland Ecosystem
Published 2024-12-01“…Wetlands ecosystems play an important role and are relevant to biotic and abiotic factors including survival of humans. Therefore, it is imperative that learners in Lesotho become sensitized to the knowledge about the ecology of wetland ecosystems. …”
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16398
Investigation of the Effect of Neck Muscle Active Force on Whiplash Injury of the Cervical Spine
Published 2018-01-01“…In this manuscript, a mixed FE human model in a sitting posture with an active head-neck was developed. …”
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16399
Advancements in Bone Replacement Techniques–Potential Uses After Maxillary and Mandibular Resections Due to Medication-Related Osteonecrosis of the Jaw (MRONJ)
Published 2025-01-01“…While various biomaterial scaffolds have shown promise in addressing these challenges, regenerating bone in this region remains complex due to its irregular shape, intricate structure, and differing cellular origins compared to other bones in the human body. Moreover, the significant and variable mechanical loads placed on the maxillofacial bones add further complexity, especially in cases of difficult-to-treat medical conditions. …”
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16400
The success of the tumor immunotherapy: neutrophils from bench to beside
Published 2025-01-01“…Neutrophils are the most abundant circulating leukocytes in human, and heterogeneous neutrophils have been increasingly recognized as important players in tumor progression. …”
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