hsa_circWDR37_016 Regulates Hypoxia-Induced Proliferation of Pulmonary Arterial Smooth Muscle Cells by Shan-Shan Li, Shuang Liang, Yao Long, Xu Chen, Xin Jin

“…Quantitative real-time PCR (qRT-PCR) analysis validated that exposure to hypoxia markedly increased the circWDR37 level in cultured human PASMCs. As evidenced by flow cytometry, 5-ethynyl-2′-deoxyuridine (EdU) incorporation, wound healing, and Tunel assay, silencing of endogenous circWDR37 attenuated proliferation and cell-cycle progression in hypoxia-exposed human PASMCs in vitro. …”
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Motor synergy and energy efficiency emerge in whole-body locomotion learning by Guanda Li, Mitsuhiro Hayashibe

“…Abstract Humans exploit motor synergies for motor control; however, how they emerge during motor learning is not clearly understood. …”
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Microplastics in a Traditional Turkish Dairy Product: Ayran by Serkan Kemal Buyukunal, Sanae Rbaibi Zipak, Karlo Muratoglu

“…Ingestion of microplastic particles (MP) through food has been associated with a multitude of health problems in humans. Although ayran is a traditional and nutritious Turkish beverage, the impact of microplastic pollution is unknown. …”
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KRAS and BRAF Mutation Detection: Is Immunohistochemistry a Possible Alternative to Molecular Biology in Colorectal Cancer? by Nicolas Piton, Francesco Borrini, Antonio Bolognese, Aude Lamy, Jean-Christophe Sabourin

“…Additionally, a mouse anti-human BRAF monoclonal antibody was tested on 30 FFPE tumor samples with known BRAF status. …”
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Ginkgolide B Blocks Vascular Remodeling after Vascular Injury via Regulating Tgfβ1/Smad Signaling Pathway by Quan Wang, Shuai Ni, Li Ling, Siqi Wang, Hanbin Xie, Zhanhong Ren

“…Additional experiments reveal that GB exerts a protective effect on vascular remodeling and further restenosis through modulation of the Tgfβ1/Smad signaling pathway in vivo and in human vascular smooth muscle cells (HVSMAs) but not in human umbilical vein endothelial cells (HUVECs) in vitro. …”
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Structure of an ex vivoDrosophila TOM complex determined by single-particle cryoEM by Agalya Periasamy, Pamela Ornelas, Thomas Bausewein, Naomi Mitchell, Jiamin Zhao, Leonie M. Quinn, Werner Kuehlbrandt, Jacqueline M. Gulbis

“…The Drosophila TOM structure presented here shows that the human and Drosophila TOM are very similar, with small conformational changes at two subunit interfaces attributable to variation in lipid-binding residues. …”
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An Immunocompetent HIV-Negative Elderly Patient with Low-Grade Fever, Generalized Lymphadenopathy, Splenomegaly, and Acute Phase Response: Do Not Forget Castleman Disease by Kalliopi Azariadis, Maria Ioannou, Kalliopi Zachou, George N. Dalekos

“…Multicentric Castleman disease (MCD) is a rare lymphoproliferative disorder that mainly affects middle-aged patients with human immunodeficiency virus (HIV) infection. However, HIV-negative patients can also be affected representing a small proportion of the total MCD cases. …”
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Research on Groundwater Drought and Sustainability in Badain Jaran Desert and Surrounding Areas Based on GRACE Satellite by Xiaojun Liu, Naiang Wang, Yixin Wang, Nan Meng, Yuchen Wang, Bin Qiao, Rongzhu Lu, Dan Yang

“…Furthermore, the Sustainability Index (SI) of the study area declined markedly from 1.00 to 0.01, underscoring the critical impact of human activities on groundwater resources in the BJDCA. …”
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Gingiva-Derived Mesenchymal Stem Cells Attenuate Imiquimod- (IMQ-) Induced Murine Psoriasis-Like Skin Inflammation by Ziyu Ye, Yanfang Liang, Bihua Lin, Yanyun Li, Xingxing Chai, Jiachun Lian, Xueying Zhang, Zhengping Che, Jincheng Zeng

“…Human gingiva-derived mesenchymal stem cells (GMSCs) are isolated from the gingival propria with promising regenerative, immunomodulatory, and anti-inflammatory properties. …”
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Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. by Joel M Montgomery, Patrick J Blair, Darin S Carroll, James N Mills, Alberto Gianella, Naomi Iihoshi, Ana M Briggiler, Vidal Felices, Milagros Salazar, James G Olson, Raisa A Glabman, Daniel G Bausch

“…Precipitation in the months preceding the outbreak was particularly heavy in comparison to other years, suggesting a possible climatic or ecological influence on rodent populations and risk of hantavirus transmission to humans. Hantavirus infection appears to be common in the Santa Cruz Department, but more comprehensive surveillance and field studies are needed to fully understand the epidemiology and risk to humans.…”
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Research on Spatial-temporal Variation Characteristics and In fluencing Factors of Annual Maximum Daily Temperature in the Pearl River Basin under the Background of Global Warming by QIN Beilei, WU Xiaoqing, ZHU Tianran, LAI Chengguang

“…Global warming and severe human activities have induced the non-stationary global climate, leading to increasingly frequent climate events like extreme high temperature, which has seriously threatened human health and socio-economic development. …”
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Addition of Zirconium Oxide for Reduction of Hydroxyapatite Layer Cracks in Ti-6Al-4V ELI Implant Materials for Improved Osseointegration by Sanny Ardhy, Gunawarman Gunawarman, Jon Affi, Yuli Yetri

“…These result is certainly good for increasing osseointegration in the human body.…”
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An unstable variant of GAP43 leads to neurodevelopmental deficiency by Mariko Noda, Ayumi Matsumoto, Hidenori Ito, Masayo Kagami, Toshihiro Tajima, Takayoshi Matsumura, Takanori Yamagata, Koh-ichi Nagata

“…While the association between GAP43 and human neurological disorders have been reported, the underlying mechanisms remain largely unknown. …”
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Micro-PET/CT Monitoring of Herpes Thymidine Kinase Suicide Gene Therapy in a Prostate Cancer Xenograft: The Advantage of a Cell-specific Transcriptional Targeting Approach by Mai Johnson, Makoto Sato, Jeremy Burton, Sanjiv S. Gambhir, Michael Carey, Lily Wu

“…The extent of tumor killing was analyzed by apoptotic staining and human prostate marker (prostate-specific antigen). …”
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A Structure Analysis for Ecological Management of Moist Tropical Forests by Adrien Djomo Njepang

“…Human interventions alter stand structure, species composition, and regeneration capacity of the forest. …”
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Non-negligible Occurrence of Errors in Gender Description in Public Data Sets by Jong Hwan Kim, Jong-Luyl Park, Seon-Young Kim

“…Due to advances in omics technologies, numerous genome-wide studies on human samples have been published, and most of the omics data with the associated clinical information are available in public repositories, such as Gene Expression Omnibus and ArrayExpress. …”
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Prevalence of <i>Leptospira</i> spp. in Lithuanian Wild Boars (<i>Sus scrofa</i>) by Birutė Karvelienė, Inga Stadalienė, Jūratė Rudejevienė, Evelina Burbaitė, Dalia Juodžentė, Marius Masiulis, Jūratė Buitkuvienė, Jurgita Šakalienė, Gintaras Zamokas

“…Even though leptospirosis in humans in Lithuania is rare, it remains a disease of significance in Europe. …”
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Microplastic accumulation in snake-eyed lizard (Ophisops elegans Menetries, 1832) after long-term monitoring: habitats matter, not years by Cantekin Dursun, Kamil Candan, Kaan Karaoğlu, Çetin Ilgaz, Yusuf Kumlutaş, Elif Yıldırım Caynak, Serkan Gül

“…It is thought that this accumulation is caused by human activities in the lizard's environment and that it enters the food web indirectly because it lives in areas with high human interaction. …”
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Turkey’s Drought Status Associated with Climate Change by Emine Su Turan

“…Due to various human activities, the accumulation of greenhouse gases in the atmosphere has increased rapidly since the industrial revolution. …”
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Online Corporate Social Responsibility Reporting in the Croatian Banking Sector by Sanda Grudić Kvasić, Ljerka Cerović, Bojana Olgić Draženović

“…Using website content analysis of all twenty-eight banks currently operating in the Croatian banking sector, corporate social responsibility disclosure is categorised in terms of themes (environment, human resources, customers and products, and community involvement). …”
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