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14721
Bridging the gap: From petri dish to patient - Advancements in translational drug discovery
Published 2025-01-01“…The article aims to showcase how these technologies improve the predictability of drug performance in human bodies and significantly speed up the drug development process. …”
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14722
Reprezentacje obiektów przyrodniczych z dziecięcej perspektywy
Published 2021-06-01“…The presented research showed also that children make conceptualization mainly through personal experiences and that when describing animals, children focus on observable animal activity and behavior, as well as animal appearance, size, the environment of living and the relation with humans. …”
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14723
Gut Microbiota and its Metabolites in Pathogenesis of NAFLD
Published 2023-02-01“…Metabolites of microbial origin are important biological molecules involved in many specific reactions of the human body. This literature review presents the results of recent studies in the field of metabolomics in patients with NAFLD. …”
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14724
Microbiome interactions and their ecological implications at the Salton Sea
Published 2022-04-01“…Although the Salton Sea was once a thriving destination for humans and wildlife, it has now degraded to the point of ecosystem collapse. …”
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14725
The emergence of cell-based protein arrays to test for polyspecific off-target binding of antibody therapeutics
Published 2024-12-01“…Cell-based protein arrays assess binding across the full human membrane proteome, ~6,000 membrane proteins each individually expressed in their native structural configuration within live or unfixed cells. …”
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14726
Une approche multidisciplinaire de la fabrique des paysages dans la longue durée dans les forêts de Blois, Russy, Boulogne et Chambord (Loir-et-Cher)
Published 2017-07-01“…The archaeological work conducted in these forests focuses on all kinds of vestiges preserved by the cover of vegetation as well as human forestry activities (Dupouey et al., 2007). …”
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14727
Sickness, Hygienic Education and Village Practice: Tuberculosis in the Life of a Cobbler
Published 2011-03-01“…Sickness and health are thus in a central position in human life. Tuberculosis, for example, was formerly a common disease in Finland. …”
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14728
Gene fitness landscapes of Vibrio cholerae at important stages of its life cycle.
Published 2013-01-01“…Vibrio cholerae has evolved to adeptly transition between the human small intestine and aquatic environments, leading to water-borne spread and transmission of the lethal diarrheal disease cholera. …”
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14729
Development and preclinical testing of a naloxone prodrug depot for extended protection against opioid overdose
Published 2025-01-01“…Preclinical studies demonstrated efficacy in rat overdose models and achieved monkey naloxone levels matching effective human therapeutic levels. Although monkey efficacy was not assessed, combined rat efficacy and monkey pharmacokinetics suggest strong potential for successful human translation.…”
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14730
A Mosquito Culex cedecei Stone and Hair (Insecta: Diptera: Culicidae)
Published 2021-09-01“…Culex cedecei is therefore considered a vector of a zoonotic pathogen that can affect human health. …”
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14731
A distant TANGO1 family member promotes vitellogenin export from the ER in C. elegans
Published 2025-02-01“…Summary: Vitellogenin is thought to share a common ancestor with human apolipoprotein B (ApoB) for systemic lipid transport. …”
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14732
Suppression of monocyte and neutrophil function by recombinant IL-2
Published 1993-01-01“…We now describe the effects of human recombinant IL-2 on human neutrophil and monocyte functions related to mobility, phagocytosis, glucose uptake, respiration and degranulation. …”
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14733
Exploring historical maps for insights into ecosystem extent and condition: a case study landscape in Poland
Published 2024-12-01“…The least natural areas were scarce and so human pressure and impacts were lower. Humans have significantly influenced this landscape by expanding mineral extraction activities and built-up areas. …”
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14734
Design and Fabrication of an Improved Vise
Published 2023“…Human effort applied to clamp the job varies from operator to operator. …”
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14735
Under the Skies of Olympus: Three Types of Divine Landscapes in the Homeric Hymns
Published 2023-10-01“… The paper discusses the landscapes of Apollo, Hermes, Pan, and Demeter in the Homeric hymns, analysing how particular landscape representations articulate the gods’ functions and identities, their relationship to humanity and the structure of the Olympic cosmos. It is argued that an in-depth examination of the representation of landscape in Ancient literature reveals patterns of representation that contribute to a deeper understanding of the religious worldview of the ancient Greeks. …”
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14736
The Prognostic Value of Adaptive Nuclear Texture Features from Patient Gray Level Entropy Matrices in Early Stage Ovarian Cancer
Published 2012-01-01“…Background: Nuclear texture analysis gives information about the spatial arrangement of the pixel gray levels in a digitized microscopic nuclear image, providing texture features that may be used as quantitative tools for prognosis of human cancer. The aim of the study was to evaluate the prognostic value of adaptive nuclear texture features in early stage ovarian cancer.…”
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14737
The Food Recall Manual
Published 2004-12-01“… The Food Science and Human Nutrition Department of the University of Florida has assembled this manual to assist food businesses, at all parts of the food chain, in learning to conduct rapid and effective product recalls. …”
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14738
Review essay: On the state of the debate in ecological theology
Published 2002-06-01“… This review essay assesses the state of the debate on a Christian Ecological Theology with specific reference to the important volume of essays Christianity and ecology: seeking the well-being of earth and humans edited by Dieter Hessel and Rosemary Ruether (2000). …”
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14739
Dezbatere de carte Cătălin Zamfir, România în criză, Editura Academiei Române, București, 2023
Published 2025-02-01“… The "Alexandru Ioan Cuza" University in Iasi, the Faculty of Philosophy and Social-Political Sciences, the Department of Sociology, Social Assistance and Human Resources hosted on 31st of October 2024 a book debate on the Cătălin Zamfir volume, Romania in crisis, Romanian Academy Publishing House, Bucharest, 2023. …”
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14740
L’histoire des ordures : de la préhistoire à la fin du dix-neuvième siècle
Published 2013-12-01“…However, the awareness of the necessity of an effective management of garbage appeared only lately in human history. The objective of this article is to present, through an essentially bibliographical approach, the way the people lived and managed their waste since the Prehistory until at the end of the XIXth century.…”
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