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  1. 14681

    Pioneering Ideas on Fuzzy Logic in al-Miyānajī's Philosophy by Mehmet Emin Koç

    Published 2024-12-01
    “… It is possible to say that human thinking and logic began with his existence. …”
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  2. 14682

    MiRNAs as major players in brain health and disease: current knowledge and future perspectives by Sarika V. Kapplingattu, Sujata Bhattacharya, Yogita K. Adlakha

    Published 2025-01-01
    “…We highlight the promising therapeutic potential of miRNAs as antitumor agents for aggressive human brain tumors including glioblastoma.…”
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  3. 14683

    Sensor and Dynamic Pricing Aware Vertical Transportation in Smart Buildings by Hyunkyoung Choi, Kyungwoon Cho, Hyokyung Bahn

    Published 2019-01-01
    “…Smart buildings are also equipped with indoor sensors that can track the movement of human beings. In this paper, we propose a new elevator control system (ECS) that utilizes two kinds of context information in smart buildings: (1) human movements estimated by indoor sensors and (2) dynamic changes of electricity price. …”
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  4. 14684

    Epigenetic regulation and post-translational modifications of ferroptosis-related factors in cardiovascular diseases by Chunlu Jing, Yupeng Wu, Yuzhu Zhang, Zaihan Zhu, Yong Zhang, Zhen Liu, Dandan Sun

    Published 2025-01-01
    “…Abstract As an important element of the human body, iron participates in numerous physiological and biochemical reactions. …”
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  5. 14685

    Review Sistem Drainase Parak Jambu Dadok Tunggul Hitam Padang Menggunakan Model EPA-SWMM by Mas Mera, Februarman Februarman, Fandi Aryadwitama Priadi

    Published 2024-06-01
    “…Flood disasters have been a never-ending problem for humans all over the world from the past to the present. …”
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  6. 14686

    Continuous Dual Resetting of the Immune Repertoire as a Basic Principle of the Immune System Function by Silvana Balzar

    Published 2017-01-01
    “…The CDR concept’s relative simplicity and concomitantly documented congruency with empirical, clinical, and experimental data suggest it may represent a plausible theoretical framework to better understand the human immune system function.…”
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  7. 14687

    La nature et les ruines : anciennes présences humaines dans le récit climatique de science‑fiction by Rémi Auvertin

    Published 2023-12-01
    “…European modernity and romanticism have made the human ruin a symbol of the passage of time and the fall of civilizations. …”
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  8. 14688

    Knowledge construction in the community of fishing women in the region of Guaraqueçaba – PR by Elaine Mandelli Arns, Faimara do Rocio Strauhs

    Published 2022-05-01
    “…Findings: The network of human and non-human elements, the process of knowledge creation, was mapped establishing a comparison between the model proposed in this community and the SECI Model. …”
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  9. 14689

    Visualization Analysis of Construction Robots Based on Knowledge Graph by Runrun Dong, Cuixia Chen, Zihan Wang

    Published 2024-12-01
    “…Future trends in the field are likely to include human-robot collaboration, intelligent construction, robot vision technology, and the cultivation of specialized talent.…”
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  10. 14690

    THE UNITED NATIONS CHARTER AND THE RESPONSIBILITY TO PROTECT: INTERROGATING THE HUMANITARIAN CRISIS IN SYRIA by ANTHONY IMEH UMOH, BARINAADAA NWINKOL

    Published 2024-08-01
    “…The United Nations Charter gives responsibility to international community to use appropriate diplomatic and other peaceful measure in accordance with Chapter VI and VIII of the Charter to help protect populations from genocide, war crimes, ethnic cleansing and crime against humanity. In the same vein, the responsibility to protect populations from genocide and other gross forms of human rights abuse emerged in 2005 as an important global principle during the UN World Summit Outcome Document. …”
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  11. 14691

    Explanation of Security Sequences of Climate Change (Case Study: Iran’s Central Drainage Basin) by Morad Kavianirad, Yadollah Karimi Pour, Hedayat Fahmi, Sadegh Karami

    Published 2017-09-01
    “…Efforts to provide security have always been of great importance to human being. In recent decades, the security issues of climate change have attracted attentions due to its sustainable consequences on the lives and civilization of humans. …”
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  12. 14692

    A Case Report of Monkeypox in a 4-Year-Old Boy from the DR Congo: Challenges of Diagnosis and Management by Anna Korsgaard Eltvedt, Michael Christiansen, Anja Poulsen

    Published 2020-01-01
    “…Furthermore, closer contact between humans and bush animals could play a role along with the ongoing difficulties of controlling HIV in the same geographical area. …”
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  13. 14693

    Photoswitch dissociation from a G protein-coupled receptor resolved by time-resolved serial crystallography by Hannah Glover, Torben Saßmannshausen, Quentin Bertrand, Matilde Trabuco, Chavdar Slavov, Arianna Bacchin, Fabio Andres, Yasushi Kondo, Robin Stipp, Maximilian Wranik, Georgii Khusainov, Melissa Carrillo, Demet Kekilli, Jie Nan, Ana Gonzalez, Robert Cheng, Werner Neidhart, Tobias Weinert, Filip Leonarski, Florian Dworkowski, Michal Kepa, Josef Wachtveitl, Michael Hennig, Joerg Standfuss

    Published 2024-12-01
    “…Abstract G protein-coupled receptors (GPCRs) are the largest family of cell surface receptors in humans. The binding and dissociation of ligands tunes the inherent conformational flexibility of these important drug targets towards distinct functional states. …”
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  14. 14694

    The Strange Case: The Unsymmetric Cisplatin-Based Pt(IV) Prodrug [Pt(CH3COO)Cl2(NH3)2(OH)] Exhibits Higher Cytotoxic Activity with respect to Its Symmetric Congeners due to Carrier... by Elisabetta Gabano, Ilaria Zanellato, Giulia Pinton, Laura Moro, Mauro Ravera, Domenico Osella

    Published 2022-01-01
    “…The complexes were tested on a panel of human tumor cell lines. Complex 2 showed an anomalous higher cytotoxicity (similar to that of cisplatin) with respect to their analogues 1 and 3. …”
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  15. 14695

    The World as God’s Property in Psalm 24:1-2 as the Source of Man’s Right Attitude Towards Creation by Janusz Nawrot

    Published 2023-02-01
    “… The ongoing discussion on various forums regarding human responsibility for the ecological state of the surrounding world, should include the voice of the word spoken in the Bible by God, the Creator of heaven and earth. …”
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  16. 14696

    G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s disease pathogenesis by Morgan G. Stykel, Shehani V. Siripala, Eric Soubeyrand, Carla L. Coackley, Ping Lu, Suelen Camargo, Sharanya Thevasenan, Gerardo Balderas Figueroa, Raphaella W.L. So, Erica Stuart, Rachi Panchal, Elissavet-Kalliopi Akrioti, Jeffery T. Joseph, Omid Haji-Ghassemi, Era Taoufik, Tariq A. Akhtar, Joel C. Watts, Scott D. Ryan

    Published 2025-01-01
    “…Linking these deficits is critical to restoring DA signaling in PD. Using murine and human pluripotent stem cell (hPSC) models of PD coupled with human postmortem tissue, we show that accumulation of α-syn micro-aggregates impairs metabolic flux through the pentose phosphate pathway (PPP). …”
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  17. 14697

    The Pathophysiological Impact of HLA Class Ia and HLA-G Expression and Regulatory T Cells in Malignant Melanoma: A Review by Lasse Lindholm Johansen, Jørgen Lock-Andersen, Thomas Vauvert F. Hviid

    Published 2016-01-01
    “…Although there is still no standardized immunological treatment worldwide, the interaction between the human leucocyte antigen (HLA) system and tumor progression seems to be a promising focus in the way of optimizing the treatment of malignant melanoma.…”
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  18. 14698

    De la bibliothèque au « Tesseract » : une représentation borgésienne de la littérature dans le film de Christopher Nolan Interstellar (2014)  by Emmanuel Buzay

    Published 2021-06-01
    “…Because it is decisive for understanding the way in which the library, as a memory of the world, rethinks humanity, its mutations, and its limits in a journey through time, the constant represented by the figure of the “book in the film” reveals a double identity which, although based on scientific knowledge, nonetheless reactivates an immemorial imaginary with its mythologies. …”
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  19. 14699

    Insulin resistance compromises midbrain organoid neuronal activity and metabolic efficiency predisposing to Parkinson’s disease pathology by Alise Zagare, Janis Kurlovics, Catarina Almeida, Daniele Ferrante, Daniela Frangenberg, Armelle Vitali, Gemma Gomez-Giro, Christian Jäger, Paul Antony, Rashi Halder, Rejko Krüger, Enrico Glaab, Egils Stalidzans, Giuseppe Arena, Jens C Schwamborn

    Published 2025-01-01
    “…To investigate insulin resistance caused pathological changes in the human midbrain, which could predispose a healthy midbrain to PD development, we exposed iPSC-derived human midbrain organoids from healthy individuals to either high insulin concentration, promoting insulin resistance, or to more physiological insulin concentration restoring insulin signalling function. …”
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  20. 14700

    From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome by Nathan Cramer, Zygmunt Galdzicki

    Published 2012-01-01
    “…Down syndrome (DS) is caused by the overexpression of genes on triplicated regions of human chromosome 21 (Hsa21). While the resulting physiological and behavioral phenotypes vary in their penetrance and severity, all individuals with DS have variable but significant levels of cognitive disability. …”
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