The question of strains in AA amyloidosis by Gunilla T. Westermark, Ebba Nyström, Sofie Nyström, K. Peter R. Nilsson, Per Hammarström, Per Westermark

“…The strain theory originates from prion disorders, but here, we provide evidence of strains in systemic amyloidosis. Human AA amyloidosis manifests as two distinct clinical phenotypes called common AA and vascular AA. …”
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Lineage tracing studies suggest that the placenta is not a de novo source of hematopoietic stem cells. by Xiaowen Chen, Joanna Tober, Martin Dominguez, Alan T Tang, Jenna Bockman, Jisheng Yang, Sneha Mani, Chin Nien Lee, Mei Chen, Triloshan Thillaikumaran, Patricia Mericko-Ishizuka, Monica Mainigi, Nancy A Speck, Mark L Kahn

“…Lastly, we found that RUNX1 and other HEC genes were not expressed in first-trimester human placenta villous ECs, suggesting that human placenta is not hemogenic. …”
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A Sociopsychological Analysis of the Profiles of the Earliest Muslims and the Nature of the Islamic Call by Mücahit Yüksel, Hakan Temir

“…Islam is the religion preached by all prophets, from the first human being and the first prophet, Adam, to the last prophet, Muhammad. …”
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Monitoring of immune activation using biochemical changes in a porcine model of cardiac arrest by Anton Amann, Bernhard Widner, Josef Rieder, Herwig Antretter, Georg Hoffmann, Viktoria Mayr, Hans-Ulrich Strohmenger, Dietmar Fuchs

“…In animal models, immune activation is often difficult to assess because of the limited availability of specific assays to detect cytokine activities. In human monocytes/macrophages, interferon-γ induces increased production of neopterin and an enhanced activity of indoleamine 2,3-dioxygenase, which degrades tryptophan via the kynurenine pathway. …”
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Comparison of ELISA and IFAT for Leishmania infantum by European and Middle Eastern diagnostic laboratories by Kurayi G. Mahachi, Marie Ozanne, Patrick Bourdeau, Juliana Sarquis, Eric Kontowicz, Laia Solano-Gallego, Luis Cardoso, Gaetano Oliva, Gad Baneth, Maria Grazia Pennisi, Angela M. Toepp, Guadalupe Miró, Margaret Carrel, Christine A. Petersen

“…Abstract Background Visceral leishmaniosis (VL) is the most severe form of human leishmaniosis, with an estimated 95% case fatality if left untreated. …”
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Automated skin melanoma diagnostics based on mathematical model of artificial convolutional neural network by D. A. Gavrilov, E. I. Zakirov, E. V. Gameeva, V. Yu. Semenov, O. Yu. Aleksandrova

“…Modern algorithms of computer vision equaled and even in some problems surpassed human capabili es. This jerk is largely due to the emergence and development of the technology of deep convolu onal neural networks.Recent developments in the fi eld of image processing and machine learning open up the prospect of crea ng systems based on ar fi cial neural convolu onal networks, superior to humans in problems of image classifi ca on, in par cular, in solving problems of analysis of various medical images. …”
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Public Health Risks Associated with Food Process Contaminants – A Review by Ahmadullah Zahir, Zhiwen Ge, Iftikhar Ali Khan

“…Moreover, prolonged exposure to these dangerous compounds might harm human health. There is limited understanding of the sources, formation processes, and hazards of food processing contaminants, and a lack of knowledge of the mechanisms involved in how to control their generation. …”
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Out-of-phase relationship of Holocene moisture variations between the northeastern and southeastern Tibetan plateau and its societal impacts by Duo Wu, Minmin Ma, Yongxiu Lu, Shilong Guo, Tao Wang, Xuyi Ma, Guanghui Dong

“…In the present study, well-dated sedimentary records with unambiguous indicators of humidity variations from the NETP and YNP were integrated, along with radiocarbon dates from human and animal bones and the remains of crop plants from archaeological sites in this region. …”
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Adolescent and adult mice use both incremental reinforcement learning and short term memory when learning concurrent stimulus-action associations. by Juliana Chase, Liyu Xia, Lung-Hao Tai, Wan Chen Lin, Anne G E Collins, Linda Wilbrecht

“…Computational modeling has revealed that human research participants use both rapid working memory (WM) and incremental reinforcement learning (RL) (RL+WM) to solve a simple instrumental learning task, relying on WM when the number of stimuli is small and supplementing with RL when the number of stimuli exceeds WM capacity. …”
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From musk to body odor: Decoding olfaction through genetic variation. by Bingjie Li, Marissa L Kamarck, Qianqian Peng, Fei-Ling Lim, Andreas Keller, Monique A M Smeets, Joel D Mainland, Sijia Wang

“…First, we found a SNP in OR51B2 that associated with trans-3-methyl-2-hexenoic acid, a key component of human underarm odor. Second, we found two linked SNPs associated with the musk Galaxolide in a novel musk receptor, OR4D6, which is also the first human OR shown to drive specific anosmia to a musk compound. …”
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Soap and water cleaning versus bleach-based cleaners for eliminating SARS-CoV-2 infection by Ekong E. Udoh, Ubong A. Udoh, Abiodun Egwuenu, Ekpereonne B. Esu, Aruk Eteng, Faithman E. Ovat, Uduak Okomo, Olabisi Oduwole, Joseph Okebe, Martin Meremikwu

“…Methods: We assessed studies which compared the effect of soap and water cleaning on SARS-CoV-2 among humans to that of bleach-based cleaning, both in households and communities. …”
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Endotoxin Triggers Tumor Initiation Events in Nontumorigenic Breast Epithelial Cells and Enhances Invasion-Related Phenotype in Pretumorigenic and Tumorigenic Breast Epithelial Cel... by Farah Yassine, Sabreen F. Fostok, Nataly Naser Al Deen, Rabih S. Talhouk

“…Results showed that short-term ET exposure upregulated matrix metalloproteinase-9 (MMP-9) activity in nontumorigenic mammary epithelial cells of mouse (SCp2) and human origins (HMT-3522 S1; S1) and upregulated inflammatory mediators including nitric oxide (NO) and interleukin 1-β in tumorigenic human breast cells (MDA-MB-231), all in a dose-dependent manner. …”
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School Leadership and Management in the Age of Artificial Intelligence (AI): Recent Developments and Future Prospects by Turgut Karakose, Tijen Tülübaş

“…With the advent of Artificial Intelligence (AI), it has become possible to invent computer systems that can perform human-like processes to tackle large data and solve complex problems. …”

Characteristics of seismic strata in the southeast Zhoushan Archipelago (East China Sea) with emphasis on shallow gas by Bing Deng, Junbing Chen

“…The presence of ultra-shallow gas-charged sediment sealed by fine-grained muddy sediment in coastal areas with frequent human disturbance suggests a high potential for sediment instability. …”
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The effect of malotilate, a derivative of malotilate and a flavenoid on eicosanoid production in inflammatory bowel disease in rats by A. P. M. van Dijk, J. H. P. Wilson, F. J. Zijlstra

“…There were marked differences in eicosanoid formation patterns between rat and human mucosa, both normal and inflamed. In view of the hyperacute nature of the mucosal damage and the marked differences in eicosanoid production, acetic acid induced colitis in rats is probably not a suitable model of ulcerative colitis in humans.…”
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hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts by Yifei Wang, Yaqin Zhang, Bing Lu, Jianbo Xi, Dickson Kofi Wiredu Ocansey, Fei Mao, Donglin Hao, Yongmin Yan

“…We also used the TGF-induced human intestinal fibroblast CCD-18Co to observe the role of hucMSC-Ex in the proliferation, migration, and activation of intestinal fibroblasts. …”
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Second harmonic generation imaging reveals entanglement of collagen fibers in the elephant trunk skin dermis by Andrew K. Schulz, Magdalena Plotczyk, Sophia Sordilla, David C. A. Gaboriau, Madeline Boyle, Krishma Singal, Joy S. Reidenberg, David L. Hu, Claire A. Higgins

“…The bimodal distribution of collagen is seen across all portions of the trunk, and is dissimilar from that of human skin where one orientation dominates within a body site. …”
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Health Risk Assessment of Pesticide Residues in Drinking Water of Upper Jhelum Region in Kashmir Valley-India by GC-MS/MS by M. Imran Ganaie, Ishrat Jan, Afshan Nabi Mayer, Alamgir A. Dar, Ishtiaq A. Mayer, Pervez Ahmed, Javid A. Sofi

“…They can therefore impair human and biota health when present over the threshold level. …”
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First whole genome report of Mangrovibacter phragmitis PSU-3885–11 isolated from a patient in Thailand by Nattarika Chaichana, Thunchanok Yaikhan, Mingkwan Yingkajorn, Nonthawat Thepsimanon, Sirikan Suwannasin, Kamonnut Singkhamanan, Sarunyou Chusri, Rattanaruji Pomwised, Monwadee Wonglapsuwan, Komwit Surachat

“…The findings also emphasize the importance of continued surveillance and genomic analysis of environmental bacteria that may emerge as opportunistic pathogens in human infections.…”
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Monitoring the Spread of Multidrug-Resistant <i>Escherichia coli</i> Throughout the Broiler Production Cycle by Victor Dellevedove Cruz, Danilo Henrique Rabaçal Alves, Jamile Kellen de Souza, Maísa Fabiana Menck-Costa, Bruno Henrique Dias de Oliva, Ana Angelita Sampaio Baptista, Alexandre Oba, Fabrizio Matté, Kácio Emílio Borges Baierle, Sérgio Paulo Dejato da Rocha, Kelly Cristina Tagliari de Brito, Benito Guimarães de Brito, Gerson Nakazato, Marcio Costa, Renata Katsuko Takayama Kobayashi

“…The monitoring of antimicrobial virulence and resistance genes are tools that have come to assist the breeding of these animals, directing possible treatments as already used in human medicine and collecting data to demonstrate possible dissemination of multidrug-resistant strains that may cause damage to industry and public health. …”
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