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Role of sclerostin in mastocytosis bone disease
Published 2025-01-01“…We assessed sclerostin, bioactive sclerostin, and SOST gene expression in HMC-1.2 human mast cell culture supernatants and plasma of SM patients (n = 39). …”
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Editorial: The Artificial Intelligence in Translational Medicine and Biomedical Research, How Future Can be Shaped?!!
Published 2023-12-01“…Additionally, the Neuralink that is introduced by Neuralink Corp. is taking a historical step after gaining the approval from FDA to start human trials. Such dramatical change in the brain interface using AI can be a solution for many diseases that human couldn’t treat. …”
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The impact of gestational age limits on abortion-related outcomes: a synthesis of legal and health evidence
Published 2025-02-01“…Methods This paper synthesizes the results of a systemic review with the identification and application of relevant international human rights standards. A search strategy was drawn up to capture public health, international human rights law, and policy evidence related to the impacts of GLs. …”
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Comparative study of packaging materials developed from fish and legume protein concentrates
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Rescue of in vitro models of CSF1R-related adult-onset leukodystrophy by iluzanebart: mechanisms and therapeutic implications of TREM2 agonism
Published 2025-01-01“…Herein, we demonstrate that iluzanebart is a potent, dose-dependent, and specific activator of TREM2 signaling in human primary cells. Iluzanebart treatment rescued viability of human monocyte-derived macrophages (hMDM) and induced pluripotent stem cell-derived human microglia (iMGL) in multiple in vitro models of CSF1R-ALSP, including in induced pluripotent stem cell (iPSC) differentiated microglia carrying the heterozygous I794T mutation found in CSF1R-ALSP patients. …”
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Geographically widespread and novel hemotropic mycoplasmas and bartonellae in Mexican free-tailed bats and sympatric North American bat species
Published 2025-01-01“…However, bacterial pathogens can have significant impacts on both human health and bat morbidity and even mortality. …”
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Role of Vigilin and RACK1 in dengue virus-Aedes aegypti-Wolbachia interactions
Published 2025-01-01“…Functional studies in human cells indicated that RACK1 interacts with Vigilin to promote dengue virus (DENV) replication. …”
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Evaluation of multidrug resistance in the Gram-negative microbiome of cancer patients and the adverse effects of their metabolites on albino rats and epithelial or fibroblasts cell...
Published 2025-01-01“…Moreover, all metabolites showed marked cytotoxicity against human normal cell lines; human mammary epithelial (MCF10A), human lung fibroblasts (WI38) and human dermal fibroblasts (HDFs). …”
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Naturally occurring influenza reassortment in pigs facilitates the emergence of intrahost virus subpopulations with distinct genotypes and replicative fitness
Published 2025-01-01“…All the IAV genotypes could replicate in various swine and human-sourced respiratory epithelial cells, and we observed that distinct reassortant genotypes recovered from a single pig could exhibit different growth abilities, especially in human cells. …”
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COEVOLUTIONARY SEMANTICS OF TECHNOLOGICAL CIVILIZATION GENESIS AND EVOLUTIONARY RISK (BETWEEN THE BIOAESTHETICS AND BIOPOLITICS)
Published 2016-12-01“…As a result, the future of human nature depends not only on the rationalist principles of ethics of Homo species (the archaism of Jurgen Habermas), but also on the holistic and emotionally aesthetic image of «Self». …”
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AIP56, an AB toxin secreted by Photobacterium damselae subsp. piscicida, has tropism for myeloid cells
Published 2025-01-01“…The discovery of AIP56-like and AIP56-related toxins in diverse organisms, including human-associated Vibrio strains, highlights the evolutionary conservation of this toxin family, suggesting that AIP56 and its homologs may share conserved receptors across species. …”
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A Review of Potentially Toxic Elements in Sediment, Water, and Aquatic Species from the River Ecosystems
Published 2024-12-01“…There is concern over potential toxic elements (PTEs) impacting river ecosystems due to human and industrial activities. The river’s water, sediment, and aquatic life are all severely affected by the release of chemical and urban waste. …”
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