Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy by Wenjing Bai, Jinxin Xu, Wenbin Gu, Danyang Wang, Ying Cui, Weidong Rong, Xiaoan Du, Xiaoxia Li, Cuicui Xia, Qingqing Gan, Guantao He, Huahui Guo, Jinfeng Deng, Yuqiong Wu, Ray-Whay Chiu Yen, Srinivasan Yegnasubramanian, Scott B. Rothbart, Cheng Luo, Linping Wu, Jinsong Liu, Stephen B. Baylin, Xiangqian Kong

“…Herein, we demonstrate that human STELLA (hSTELLA) is inadequate, while mouse STELLA (mSTELLA) is fully proficient in inhibiting the abnormal DNA methylation and oncogenic functions of UHRF1 in human cancer cells. …”
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Stratégies de subsistance et analyse culturelle de populations néolithiques de Ligurie : approche par l’étude isotopique (δ13C et δ15N) des restes osseux by Gwenaëlle Le Bras-Goude, Didier Binder, Vincenzo Formicola, Christine Couture-Veschambre, Jean-Jacques Hublin, Isabelle Richards, Henri Duday

“…For the last ten millennia humans have learned how to manage and produce their own food resources. …”
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Research on inverse simulation of physical training process based on wireless sensor network by Chu Rouxia, Chen Xiaodong, Tao Shifang, Yang Donghai

“…In order to improve the control ability of the human body in the process of physical training, it is necessary to carry out the inverse simulation analysis of the physical training process and establish the process control model of the physical training. …”
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An android can show the facial expressions of complex emotions by Alexander Diel, Wataru Sato, Chun-Ting Hsu, Alexander Bäuerle, Martin Teufel, Takashi Minato

“…Androids can show human-like facial expressions of basic emotions. …”
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Gut-Lung Microbiota in Chronic Pulmonary Diseases: Evolution, Pathogenesis, and Therapeutics by Chang Yi Shi, Chen Huan Yu, Wen Ying Yu, Hua Zhong Ying

“…The microbiota colonized in the human body has a symbiotic relationship with human body and forms a different microecosystem, which affects human immunity, metabolism, endocrine, and other physiological processes. …”
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Director Eligibility: Corporations and AI by Daisuke ASAOKA

“…Such a corporation, with its lack of human intervention, is essentially a thing that consists of capital, in a transformation of the traditional view of a corporation as a combination of humans and capital.…”
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Diversity and Potential Cross-Species Transmission of Rotavirus A in Wild Animals in Yunnan, China by Xiang Le, Yinzhu Tao, Binghui Wang, Yutong Hou, Yuting Ning, Junjie Hou, Ruimei Wang, Qian Li, Xueshan Xia

“…Rotavirus A (RVA) is the primary enteric pathogen of humans and many other species. However, RVA interspecies transmission remains poorly understood. …”
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Aligning knowledge concepts to whole slide images for precise histopathology image analysis by Weiqin Zhao, Ziyu Guo, Yinshuang Fan, Yuming Jiang, Maximus C. F. Yeung, Lequan Yu

“…However, previous studies only learn from training data, posing a stark contrast to how human clinicians teach each other and reason about histopathologic entities and factors. …”
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O moralnych obowiązkach ludzi wobec zwierząt. Etyka Gary’ego Francione by Dorota Probucka

“…In his opinion, neither of these philosophers did not escape from the anthropocentric paradigm binding the moral obligations to animals with the primacy of human interest. Singer believed that only humans have the ability to plan their own future, and only they want to live and extend their own existence. …”
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A Practical Review of Cytomegalovirus in Gastroenterology and Hepatology by Ali Y. Fakhreddine, Catherine T. Frenette, Gauree G. Konijeti

“…Human cytomegalovirus (CMV) is a ubiquitous Herpesviridae virus with a wide spectrum of pathology in humans. …”
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Bats as an Important Source of Antimicrobial-Resistant Bacteria: A Systematic Review by Julio D. Soto-López, Manuel Diego-del Olmo, Pedro Fernández-Soto, Antonio Muro

“…<b>Conclusions</b>: Surveillance is essential to control the emergence of resistant bacteria related to bats, which could eventually affect humans, as this is a problem of a ‘One Health’ nature, with effects on human, animal, and environmental health.…”
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Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo by Juan A. Garcia-Sanchez, Estelle Bonnet, Céline Loubatier, Anne Doye, Guillaume Paillier, Fabien Segui, Frédéric Larbret, Paul Chaintreuil, Ludovic Batistic, Cédric Torre, Marcel Deckert, Jolanta Polanowska, Patrick Munro, Laurent Boyer, Orane Visvikis

“…Dysregulation of TFEB is associated with a range of human diseases, and understanding the regulatory mechanisms of TFEB is crucial for identifying potential drug targets. …”
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Clinical Manifestation, Histopathology, and Imaging of Traumatic Injuries Caused by Brazilian Porcupine (Sphiggurus villosus) Quills by Lívia M. Araújo Jorge, Fred Bernardes Filho, Fabrício Lamy, Laila Klotz A. Balassiano, Loan Towersey, Roderick Hay, Marco Andrey C. Frade

“…Injuries to humans caused by porcupines are rare. However, they may occur due to the proximity of urban areas and the animal’s habitat in areas such as the Floresta da Tijuca in Rio de Janeiro. …”
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Mechanisms of trematodiases pathogenicity: the presence of the secretory proteins from the liver fluke Opisthorchis felineus in the gallbladder tissues of the patients with chronic... by M. Y. Pakharukova, A. V. Kovner, A. N. Trigolubov, E. N. Fedin, E. S. Mikhailova, S. G. Shtofin, A. I. Autenshlyus, V. A. Mordvinov

“…We demonstrated by immunohistochemistry assay using antibodies against recombinant O. felineus proteins that thioredoxin peroxidase and glutathione-S-transferase could be detected in the biliary duct epithelium of the experimental animals and in human gallbladder tissues. Moreover, these proteins could also be detected in human gallbladder infiltrated cells and underlying connective tissues. …”
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Eksperyment medyczny przeprowadzany na organizmie ludzkim – aspekty prawa międzynarodowego, europejskiego i krajowego by Leszek Karski

“…The Convention for the Protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine is the subject of analysis in the third part of the paper. …”
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Historical Case of Cervical Penetrating Wound: From First Aid to Surgical Intervention by Koné Fatogoma Issa, Keïta Mohamed Amadou, Soumahoro Siaka, Konaté N’faly, Diarra Kassim, Timbo Samba Karim

“…We report a case of cervical penetrating wound by posing the problem of its support and by analyzing the chain of survival of a patient to human sacrifice. Case Report. It was an 11-year-old boy admitted to the hosting service of cervical penetrating wound emergency occurring in a context of human sacrifice by weapon (knife). …”
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Employees' perceptions of the implementation of Akhlak values at PT Pegadaian by Antoni Ludfi Arifin, Taufan Maulamin, Resista Vikaliana, Rully Yusuf

“…Its employees also respect values-driven organizations. This is a typical human resource on a network that places workers and decision makers. …”
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Pesticide residues in vegetables produced in rural south-western Uganda by Hannington, Ngabirano, Grace, Birungi

“…Pesticide residues may lower food quality and pose risk to human health. Therefore, regulation and monitoring pesticide residues in vegetables produced in southwestern Uganda in order to avoid harmful effects on human health would be paramount.…”
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DigiLoCS: A leap forward in predictive organ-on-chip simulations. by Manoja Rajalakshmi Aravindakshan, Chittaranjan Mandal, Alex Pothen, Stephan Schaller, Christian Maass

“…Finally, we illustrate the clinical significance of this approach by applying the findings to humans, utilising propranolol as a proof-of-concept example. …”
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Metabolomic Links between Sugar-Sweetened Beverage Intake and Obesity by Bingjie Zhou, Reiko Ichikawa, Laurence D. Parnell, Sabrina E. Noel, Xiyuan Zhang, Shilpa N. Bhupathiraju, Caren E. Smith, Katherine L. Tucker, Jose M. Ordovas, Chao-Qiang Lai

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