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    Synthesis of CF<sub>3</sub>-Indazoles via Rh(III)-Catalyzed C-H [4+1] Annulation of Azobenzenes with CF<sub>3</sub>-Imidoyl Sulfoxonium Ylides by Yilong Shang, Chen Li, Guiqiu Wang, Guiwei Yao, Hongliang Wu, Xun Chen, Ruirui Zhai

    Published 2025-01-01
    “…Moreover, the antitumor activities of selected CF<sub>3</sub>-indazoles against human cancer cell lines were also studied, and the results indicated that several compounds displayed considerable antiproliferative activities.…”
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  3. 12123

    RETRACTED ARTICLE: P16INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency by Jianliang Jin, Jianguo Tao, Xin Gu, Zhenzhen Yu, Rong Wang, Guoping Zuo, Qing Li, Xianhui Lv, Dengshun Miao

    Published 2017-08-01
    “…The effect of Bmi-1 deficiency on epithelial-to-mesenchymal transition (EMT) was examined in Bmi-1-knockdown human renal proximal tubular epithelial (HK2) cells, which were treated with concentrated conditioned medium (CM) from the fifth-passage renal interstitial fibroblasts (RIFs) of above three group mice or with exogenous TGF-β1. …”
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    Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson’s Disease Patients by William Haylett, Chrisna Swart, Francois van der Westhuizen, Hayley van Dyk, Lize van der Merwe, Celia van der Merwe, Ben Loos, Jonathan Carr, Craig Kinnear, Soraya Bardien

    Published 2016-01-01
    “…Parkin, an E3 ubiquitin ligase, is involved in respiratory chain function, mitophagy, and mitochondrial dynamics. Human cellular models with parkin null mutations are particularly valuable for investigating the mitochondrial functions of parkin. …”
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    From contamination to detection: The growing threat of heavy metals by Basma Hossam Abdelmonem, Lereen T. Kamal, Rana M. Elbaz, Mohamed R. Khalifa, Anwar Abdelnaser

    Published 2025-01-01
    “…Heavy metals like lead, mercury, cadmium, and arsenic are environmental pollutants that accumulate in ecosystems and pose significant health risks to humans and wildlife, primarily through food chain contamination where plants absorb heavy metals, affecting their growth and threatening consumer health. …”
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    What is the relationship between exposure to environmental pollutants and severe mental disorders? A systematic review on shared biological pathways by Pierluigi Catapano, Mario Luciano, Salvatore Cipolla, Daniela D'Amico, Alessandra Cirino, Maria Chiara Della Corte, Gaia Sampogna, Andrea Fiorillo

    Published 2025-02-01
    “…The 47 papers included in the review were divided into two groups: those conducted on human participants (15 studies) and those utilizing animal models (31 studies); one study included both humans and animals. …”
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  20. 12140

    Potential Application of Electrical Stimulation in Stem Cell-Based Treatment against Hearing Loss by Mingliang Tang, Xiaoqian Yan, Qilin Tang, Rongrong Guo, Peng Da, Dan Li

    Published 2018-01-01
    “…Deafness is a common human disease, which is mainly caused by irreversible damage to hair cells and spiral ganglion neurons (SGNs) in the mammalian cochlea. …”
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