FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models by Timothy Weeden, Tyler Picariello, Brendan Quinn, Sean Spring, Pei-Yi Shen, Qifeng Qiu, Benjamin F. Vieira, Lydia Schlaefke, Ryan J. Russo, Ya-An Chang, Jin Cui, Monica Yao, Aiyun Wen, Nelson Hsia, Tama Evron, Katy Ovington, Pei-Ni Tsai, Nicholas Yoder, Bo Lan, Reshmii Venkatesan, John Hall, Cody A. Desjardins, Mo Qatanani, Scott Hilderbrand, John Najim, Zhenzhi Tang, Matthew K. Tanner, Romesh Subramanian, Charles A. Thornton, Oxana Ibraghimov-Beskrovnaya, Stefano Zanotti

“…HSALR and TfR1 hu/mu ;DMSXL Tg/Tg mice were used as models of myotonic dystrophy, the latter expresses human TfR1 and a human DMPK RNA with >1,000 CUG repeats. …”
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Amelioration of liver fibrosis with autologous macrophages induced by IL-34-based condition by Yuichi Igarashi, Haruka Wada, Masato Muto, Ryohei Sone, Yoshinori Hasegawa, Ken-ichiro Seino

“…Similar macrophages could be differentiated from human CD14+ monocytes in the presence of interleukin 34 plus interleukin 4, and a therapeutic effect was observed using a humanized mouse model. …”
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Dynamin-1 is a potential mediator in cancer-related cognitive impairment by Ding Quan Ng, Casey Hudson, Tracy Nguyen, Sukesh Kumar Gupta, Yong Qin Koh, Munjal M. Acharya, Alexandre Chan

“…Through a stepwise approach, this study investigated the role of DNM1 in CRCI pathogenesis, incorporating both human data and animal models. The human study recruited newly diagnosed, chemotherapy-naïve adolescent and young adult cancer and non-cancer controls to complete a cognitive instrument (FACT-Cog) and blood draws for up to three time points. …”
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Studies on humoral immunity in dogs after use of rabies inactivated vaccines formulated with Montanide ISA 70 VG and GEL 01 adjuvants by A. N. Balashov, M. I. Doronin, A. V. Borisov, D. A. Lozovoy, D. V. Mikhalishin, V. A. Starikov

“…As an acute endemic infection, it poses a considerable danger to both animals and humans. The leading role in the transmission of rabies to humans belongs to diseased dogs; stray animals can be potential sources of rabies agent, which increases the risk of transmitting a deadly virus to humans. …”
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Understanding Recruiters’ Acceptance of Artificial Intelligence: Insights from the Technology Acceptance Model by Filomena Almeida, Ana Junça Silva, Sara L. Lopes, Isabel Braz

“…Specifically, the findings show the importance of ethical considerations and maintaining human involvement to ensure a balanced and effective integration of AI tools.…”
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La nocturnité au quotidien chez les Indiens tseltal du Chiapas (Mexique) by Aurore Monod Becquelin, Marie Chosson

“…This analysis invites us to scrutinise the Tseltal night from the perspective of its role as an agent of behaviours, thoughts, attitudes, and corporeal habits among these natives of the Mexican Highlands.As the home of sleep, night enables the dreamer to mix with supernatural beings, making accessible and visible a dynamic cosmos in which plants, animals, humans and nonhumans interact. However, certain traits that define this night extend beyond the nocturnal part of the nychthemeron in order to emerge on its diurnal side, what we call manifestations of nocturnity. …”
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A Most Eminent Victorian: Thomas Henry Huxley by Sherrie Lyons

“…Huxley maintained that the question of “man’s place in nature” should be approached independently of the question of origins, yet at the same time argued passionately and eloquently that even if humans shared a common a origin with the apes, this did not make humans any less special. …”
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Experimental and Analytical Study on the Vibration Performance of U-Shaped Steel-Concrete Composite Hollow Waffle Slab by Xi Zhang, Qiming Wang, Yousan Wang, Qing Li

“…Third, the CHW slab shows excellent vibration serviceability proved by the frequency, accelerations, and human perceptions threshold with the current codes. …”
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Automated Creation and Provisioning of Decision Information Packages for the Smart Factory by Eva Hoos, Pascal Hirmer, Bernhard Mitschang

“…To support correct and efficient decision making, human actors have to be provided with relevant data depending on the current context. …”
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The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model by Jan Dusek, Ivana Mejdrová, Klára Dohnalová, Tomas Smutny, Karel Chalupsky, Maria Krutakova, Josef Skoda, Azam Rashidian, Ivona Pavkova, Kryštof Škach, Jana Hricová, Michaela Chocholouskova, Lucie Smutna, Rajamanikkam Kamaraj, Miloš Hroch, Martin Leníček, Stanislav Mičuda, Dirk Pijnenburg, Rinie van Beuningen, Michal Holčapek, Libor Vítek, Magnus Ingelman-Sundberg, Oliver Burk, Thales Kronenberger, Radim Nencka, Petr Pavek

“…Through comprehensive analyses utilizing lipidomics, bile acid metabolomics, and transcriptomics in humanized PXR-CAR-CYP3A4/3A7 mice fed high-fat and high-cholesterol diets, we demonstrate that MI-883 significantly reduces plasma cholesterol levels and enhances fecal bile acid excretion. …”
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Scale-free behavior of weight distributions of connectomes by Michelle Cirunay, Géza Ódor, István Papp, Gustavo Deco

“…In this work, we investigate the weighted degree and connection length distributions of the KKI-113 and KKI-18 human connectomes, the fruit fly, and the mouse retina. …”
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The Dynamics of Labor Income Share in an Era of Robotic Automation: A Panel Data Analysis in High-Level Automation Countries by Erkişi Kemal, Çetin Melike

“…This study examines the impact of robotic capital, physical capital, technological change, human capital, and trade globalization on labor income share dynamics in the era of robotic automation. …”
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‘We Need to Ask Ourselves’: We, As A Marker of (Inter)Subjectivity in Academic Debate by Barczewska Shala

“…In contrast, Lennox’s uses are primarily inclusive, placing himself, Dawkins, and all scientists as part of the human race and using the human predicament as his main argument. …”
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Deep Learning Approach for Ascaris lumbricoides Parasite Egg Classification by Narut Butploy, Wanida Kanarkard, Pewpan Maleewong Intapan

“…For their reason, computer technology is considered to aid humans. With the benefit of speed and ability of computer technology, image recognition is adopted to recognize images much more quickly and precisely than human beings. …”
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HuBot: A biomimicking mobile robot for non-disruptive bird behavior study by Lyes Saad Saoud, Loïc Lesobre, Enrico Sorato, Saud Al Qaydi, Yves Hingrat, Lakmal Seneviratne, Irfan Hussain

“…The Houbara bustard, an avian species of conservation concern, poses significant challenges to researchers because of its elusive nature and sensitivity to human disturbances. Traditional research methods, often reliant on human observations, face some challenges and can inadvertently affect bird behavior. …”
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“That Sottish and Selfish principle”: Cugoano on Self-Interest, Imagination, and Moral Wrongdoing by Aminah Hasan-Birdwell

“…In a general sense, Cugoano depicts a form of moral wrongdoing or behavior that applies to humanity as a whole and is essentially a state of selfishness in which reason is superseded by a “viciated imagination.” …”
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Ticks and tick-borne pathogens on Belle-Île-en-Mer: An exploratory study in a western French island environment by A. Haidar-Ahmad, C. Barthel, P. Boyer, G. Joncour, B. Degeilh, N. Boulanger

“…The high prevalence of Rickettsia infection in Dermacentor indicates an additional risk of human rickettsioses.…”
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Postharvest Practices and Farmers’ Knowledge in Managing Maize Pests in the Eastern Cape Province, South Africa by Bongumusa Charles Gumede, Simon Kamande Kuria

“…Most farmers (57%) cultivated maize for human consumption, income generation, and livestock feeding. …”
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Plasma Gelsolin Levels Decrease in Diabetic State and Increase upon Treatment with F-Actin Depolymerizing Versions of Gelsolin by Neeraj Khatri, Amin Sagar, Nagesh Peddada, Vikas Choudhary, Bhupinder Singh Chopra, Veena Garg, Renu Garg, Ashish

“…The study aims to map plasma gelsolin (pGSN) levels in diabetic humans and mice models of type II diabetes and to evaluate the efficacy of gelsolin therapy in improvement of diabetes in mice. …”
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Koncepcja ekorozwoju w ujęciu Stefana Kozłowskiego by Grzegorz Embros

“…The models take into account a human factor, environment, techniques as well as energy and information. …”
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