Effects of age and diet on triglyceride metabolism in mice by Kathryn M. Spitler, Shwetha K. Shetty, Brandon S.J. Davies

“…Both age and diet can contribute to alterations in triglyceride metabolism and subsequent metabolic disease. In humans, plasma triglyceride levels increase with age. …”
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Changes of Air Pollutants in Urban Cities during the COVID-19 Lockdown-Sri Lanka by Buddhi Pushpawela, Sherly Shelton, Gayathri Liyanage, Sanduni Jayasekara, Dimuthu Rajapaksha, Akila Jayasundara, Lesty Das Jayasuriya

“…During the lockdown period, human activities were significantly reduced, causing significant reductions in industrial operations and transportation activities, further reducing emissions and improving air quality in two cities. …”
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Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice by Md Imam Faizan, Gagandeep Kaur, Sadiya Bi Shaikh, Felix Effah, Hoshang Unwalla, Irfan Rahman

“…Abstract The use of genetically diverse mouse models offers a more accurate reflection of human genetic variability, improving the translatability of findings to heterogeneous human populations. …”
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Did Turkey Experience Reductions in Air Pollution During The Covid-19 Lockdown and Partial Lockdown? by İsmet Yener, Kazım Onur Demirarslan

“…Air pollution, one of humanity's essential environmental problems due to the increasing population and urbanization, negatively affects the ecosystem and public health. …”
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Acceptability of artificial intelligence in breast screening: focus groups with the screening-eligible population in England by Jo Waller, Rumana Newlands, Lauren Gatting, Angie A Kehagia, Syeda Ahmed, Priscilla Meccheri

“…Data were analysed using a reflexive thematic analysis.Results Four themes described public perceptions of AI in breast screening found in this study: (1) Things going wrong and being missed summarises a predominant and pervasive concern about an AI tool being used in breast screening; (2) Speed of change and loss of control captures a positive association of AI with technological advances held by the women but also feelings of things being out of their control, and that they were being left behind and in the dark; (3) The importance of humans reports concern around the possibility that AI excludes humans and renders them redundant and (4) Desire for thorough research, staggered implementation and double-checking of scans included insistence that any AI be thoroughly trialled, tested and not solely relied on when initially implemented.Conclusions It will be essential that future decision-making and communication about AI implementation in breast screening (and, likely, in healthcare more widely) address concerns surrounding (1) the fallibility of AI, (2) lack of inclusion, control and transparency in relation to healthcare and technology decisions and (3) humans being left redundant and unneeded, while building on women’s hopes for the technology.…”
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Alpha synuclein overexpression can drive microbiome dysbiosis in mice by Timothy R. Sampson, Zachary D Wallen, Woong-Jai Won, David G. Standaert, Haydeh Payami, Ashley S. Harms

“…As such, several experimental rodent and non-human primate models of α-syn overexpression recapitulate some of the hallmark pathophysiologies of PD. …”
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Risk characterisation of chemicals of emerging concern in real-life water reuse applications by Jan C. Specker, Antonia Praetorius, Milo L. de Baat, Nora B. Sutton, Annemarie P. van Wezel

“…Environmental risks could be assessed for 77 % of detected CECs, while the human health risk assessment is limited to 28 %. …”
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BREEDING FOR ANTIOXIDANT CONTENT IN GRAIN AS A PROMISING TREND IN OBTAINING HEALTHY FOOD PRODUCTS by V. I. Polonskiy, I. G. Loskutov, A. V. Sumina

“…The substances that may aid to prevent a number of serious human diseases include antioxidants, while one of the important quality parameters in food products and their ingredients is their antioxidant activity. …”
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Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization by Hang Xian, Huan Guo, Yuan-Ying Liu, Sui-Bin Ma, Rui Zhao, Jian-Lei Zhang, Hang Zhang, Rou-Gang Xie, Xu-Cheng Guo, Jie Ren, Sheng-Xi Wu, Ceng Luo, Rui Cong

“…The consistent results in both humanity and rodents endow great potential to future transformation of clinical practice.…”
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Zooarchaeological investigation of the Hoabinhian exploitation of reptiles and amphibians in Thailand and Cambodia with a focus on the Yellow-headed Tortoise (Indotestudo elongata... by Bochaton, Corentin, Chantasri, Sirikanya, Maneechote, Melada, Claude, Julien, Griggo, Christophe, Naksri, Wilailuck, Forestier, Hubert, Sophady, Heng, Auertrakulvit, Prasit, Bowonsachoti, Jutinach, Zeitoun, Valéry

“…This gap in research hinders a complete comprehension of past human subsistence strategies and economies, as only a limited number of comprehensive studies encompassing all the taxa found in archaeological sites have been conducted thus far. …”
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An AI-Based Digital Scanner for <i>Varroa destructor</i> Detection in Beekeeping by Daniela Scutaru, Simone Bergonzoli, Corrado Costa, Simona Violino, Cecilia Costa, Sergio Albertazzi, Vittorio Capano, Marko M. Kostić, Antonio Scarfone

“…Detecting the parasite and defining the intervention thresholds for effective treatment is a difficult and time-consuming task; different detection methods exist, but they are mainly based on human eye observations, resulting in low accuracy. …”
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The question of strains in AA amyloidosis by Gunilla T. Westermark, Ebba Nyström, Sofie Nyström, K. Peter R. Nilsson, Per Hammarström, Per Westermark

“…The strain theory originates from prion disorders, but here, we provide evidence of strains in systemic amyloidosis. Human AA amyloidosis manifests as two distinct clinical phenotypes called common AA and vascular AA. …”
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Monitoring of immune activation using biochemical changes in a porcine model of cardiac arrest by Anton Amann, Bernhard Widner, Josef Rieder, Herwig Antretter, Georg Hoffmann, Viktoria Mayr, Hans-Ulrich Strohmenger, Dietmar Fuchs

“…In animal models, immune activation is often difficult to assess because of the limited availability of specific assays to detect cytokine activities. In human monocytes/macrophages, interferon-γ induces increased production of neopterin and an enhanced activity of indoleamine 2,3-dioxygenase, which degrades tryptophan via the kynurenine pathway. …”
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Automated skin melanoma diagnostics based on mathematical model of artificial convolutional neural network by D. A. Gavrilov, E. I. Zakirov, E. V. Gameeva, V. Yu. Semenov, O. Yu. Aleksandrova

“…Modern algorithms of computer vision equaled and even in some problems surpassed human capabili es. This jerk is largely due to the emergence and development of the technology of deep convolu onal neural networks.Recent developments in the fi eld of image processing and machine learning open up the prospect of crea ng systems based on ar fi cial neural convolu onal networks, superior to humans in problems of image classifi ca on, in par cular, in solving problems of analysis of various medical images. …”
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Public Health Risks Associated with Food Process Contaminants – A Review by Ahmadullah Zahir, Zhiwen Ge, Iftikhar Ali Khan

“…Moreover, prolonged exposure to these dangerous compounds might harm human health. There is limited understanding of the sources, formation processes, and hazards of food processing contaminants, and a lack of knowledge of the mechanisms involved in how to control their generation. …”
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Out-of-phase relationship of Holocene moisture variations between the northeastern and southeastern Tibetan plateau and its societal impacts by Duo Wu, Minmin Ma, Yongxiu Lu, Shilong Guo, Tao Wang, Xuyi Ma, Guanghui Dong

“…In the present study, well-dated sedimentary records with unambiguous indicators of humidity variations from the NETP and YNP were integrated, along with radiocarbon dates from human and animal bones and the remains of crop plants from archaeological sites in this region. …”
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Soap and water cleaning versus bleach-based cleaners for eliminating SARS-CoV-2 infection by Ekong E. Udoh, Ubong A. Udoh, Abiodun Egwuenu, Ekpereonne B. Esu, Aruk Eteng, Faithman E. Ovat, Uduak Okomo, Olabisi Oduwole, Joseph Okebe, Martin Meremikwu

“…Methods: We assessed studies which compared the effect of soap and water cleaning on SARS-CoV-2 among humans to that of bleach-based cleaning, both in households and communities. …”
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The effect of malotilate, a derivative of malotilate and a flavenoid on eicosanoid production in inflammatory bowel disease in rats by A. P. M. van Dijk, J. H. P. Wilson, F. J. Zijlstra

“…There were marked differences in eicosanoid formation patterns between rat and human mucosa, both normal and inflamed. In view of the hyperacute nature of the mucosal damage and the marked differences in eicosanoid production, acetic acid induced colitis in rats is probably not a suitable model of ulcerative colitis in humans.…”
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hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts by Yifei Wang, Yaqin Zhang, Bing Lu, Jianbo Xi, Dickson Kofi Wiredu Ocansey, Fei Mao, Donglin Hao, Yongmin Yan

“…We also used the TGF-induced human intestinal fibroblast CCD-18Co to observe the role of hucMSC-Ex in the proliferation, migration, and activation of intestinal fibroblasts. …”
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Health Risk Assessment of Pesticide Residues in Drinking Water of Upper Jhelum Region in Kashmir Valley-India by GC-MS/MS by M. Imran Ganaie, Ishrat Jan, Afshan Nabi Mayer, Alamgir A. Dar, Ishtiaq A. Mayer, Pervez Ahmed, Javid A. Sofi

“…They can therefore impair human and biota health when present over the threshold level. …”
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