Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals by Ruxing Zhao, Yujing Sun, Yongyuan Zhang, Weili Wang, Shouyu Wang, Chuang Wang, Jinbo Liu, Ling Gao, Zhao Hu, Jianchun Fei, Xinguo Hou, Huizhen Zheng, Li Chen

“…The immune system poses the critical interactive chain between the human body and the virus. Here, we make efforts to examine whether comorbidity with type 2 diabetes (T2D) affects the immunological response in COVID-19 patients. …”
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Enhanced preoperative prediction of breast lesion pathology, prognostic biomarkers, and molecular subtypes using multiple models diffusion-weighted MR imaging by Litong He, Feng Li, Yanjin Qin, Yuling Li, Qilan Hu, Zhiqiang Liu, Yunfei Zhang, Tao Ai

“…Significant differences in IVIM-D, IVIM-D*, and DKI-MK values were observed between human epidermal growth factor receptor 2 (HER2)-negative and HER2-positive tumors. …”
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Extracellular vesicles derived from creeping fat stem cells promote lymphatic function and restrain inflammation of Crohn's disease by Weigang Shu, Yongheng Wang, Mengfan Chen, Xiaoli Zhu, Fangtao Wang, Chunqiu Chen, Peng Du, Alexandra Bartolomucci, Xin Su, Xiaolei Wang

“…Methods To evaluate the regulative roles of CrF‐EVs on lymphatic functions, in vitro assays were performed using human lymphatic endothelial cells (HLECs). Next, Interleukin 10 knock‐out (Il‐10−/−) mice were used to assess the biological functions of CrF‐EVs in spontaneous mesenteritis and colitis. …”
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Resolution of oncogene-induced senescence markers in HPV-infected cervical cancer tissue by Ashraf I. Khasawneh, Sofian Al Shboul, Nisreen Himsawi, Amani Al Rousan, Nisreen Abu Shahin, Mohammed El-Sadoni, Ahmad Alhesa, Ala’ Abu Ghalioun, Suzan Khawaldeh, Bayan Shawish, Salem Abu Mahfouz, Mais Al-Shayeb, Shatha Abo Dawoud, Raghad Tlilan, Mohammad Nuseir, Moureq R. Alotaibi, Ola Abu Al Karsaneh, Fida Asali, Marcos Yébenes Mayordomo, Raghda Barham, Rame Khasawneh, Tareq Saleh

“…Moreover, whether cervical epithelial cells that are part of the premalignant cervical intraepithelial neoplasia (CIN), exhibit markers of OIS in Human Papillomavirus (HPV)-infected tissue, has not been investigated. …”
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Catalytic effect of Fe@Fe2O3 nanowires and Fenton process on carbamazepine removal from aqueous solutions using response surface methodology by M.M. Amin, S. Yousefinejad, M. Dehghani, S. Rahimi

“…Due to toxicity and bio-stability of this psychotropic pharmaceutical in the environment and humans, its removal efficiency and mineralization are important. …”
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Development and utilization of Treponema pallidum expressing green fluorescent protein to study spirochete-host interactions and antibody-mediated clearance: expanding the toolbox... by Kristina N. Delgado, Crystal F. Vicente, Christopher M. Hennelly, Farhang Aghakhanian, Jonathan B. Parr, Kevin P. Claffey, Justin D. Radolf, Kelly L. Hawley, Melissa J. Caimano

“…Fluorescent TPA strains provide a powerful new tool for elucidating host-pathogen interactions that enable the syphilis spirochete to establish infection and persistent long-term within its obligate human host.…”
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The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Cont... by S. Abramov, S. Sokolovskyi, A. Gozhenko, I. Sobko, G. Titov, V. Gladyshev, M. Khmil, Ugis Kletnieks

“…Notably, PLANTOR does not contain procoagulant minerals or nanoparticles that could remain in the human body, and therefore does not belong to means with a chemical or biochemical mechanism of action. …”
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Network meta-analysis of cadmium toxicity against Chlorella vulgaris and the role of growth stimulants and macronutrients by M. Iqhrammullah, S. Saudah, M. Monalisa, F. Fahrurrozi, S.A. Akbar, S.S. Lubis

“…BACKGROUND AND OBJECTIVES: The presence of heavy metals, specifically cadmium, in the environment poses significant threats to both ecological systems and human health. However, microalgae have shown potential in addressing this issue through their ability to absorb cadmium and produce valuable biomass, making them a promising solution for bioremediation. …”
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Comparison of radiation esophagitis associated with daytime versus evening radiotherapy in patients with esophageal carcinoma by Yun Xing, Yutian Yin, Liang Yu, Cong Zhang, Guangjin Chai, Bo Lyu, Bin Wang, Lina Zhao, Geng Xiang

“…Abstract Purpose Based on the demonstration of a circadian rhythm in the human oral mucosa cell cycle, with most cells in the G2/M phase in the afternoon and at night, the present study evaluated the severity of acute radiation esophagitis and treatment outcomes in esophageal squamous cell carcinoma patients receiving radiotherapy (RT) in the daytime versus in the evening. …”
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Effect of Tonifying deficiency and Zhengqi porridge on immune function reconstruction in HIV/AIDS patients with Qi deficiency (补虚正气粥对艾滋病气虚型患者免疫功能重建的影响研究)... by WEI Yan (魏艳), LI shu (李树), YUAN Hongxia (袁洪霞), ZHANG Ying (张英), LIU Xiaoli (刘小丽), LIU Lingling (刘玲玲)

“…Objective To observe the effect of Tonifying deficiency and Zhengqi porridge on immune function reconstruction of HIV/AIDS patients with Qi deficiency. Methods Sixty (Human Immunodeficiency Virus/ Acquired Immunodeficiency Syndrome)HIV/AIDS patients admitted to the center for Disease Control and prevention in Huichuan District of Zunyi City were randomly divided into control group and treatment group by random number table. …”
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Secreted LGALS3BP facilitates distant metastasis of breast cancer by Seung-Su Kim, Issac Park, Jeesoo Kim, Na-Lee Ka, Ga Young Lim, Mi-Ye Park, Sewon Hwang, Ji-Eun Kim, So Yeon Park, Jong-Seo Kim, Hyun-Woo Rhee, Mi-Ock Lee

“…Secreted LGALS3BP in the TAMR secretome helped BC cells adhere to the extracellular matrix and promoted the tube formation of human umbilical vein endothelial cells. Compared with sensitive cells, xenograft animal experiments with MCF7/TAMR cells showed increased pulmonary metastasis, which completely disappeared in LGALS3BP-knockdown TAMR cells. …”
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From cellular senescence towards age-related macular degeneration: the role of telomeres by L.K. Moshetova, O.I. Abramova, K.I. Turkina, O.P. Dmitrenko, N.S. Karpova

“…Karpova²</b> </p> <p> <b>¹Russian Medical Academy of Continuous Professional Education, Moscow, <br> &nbsp;Russian Federation</b> </p> <p> <b>²Institute of General Pathology and Pathophysiology, Moscow, Russian Federatio</b>s&nbsp; </p> <p> <i>Since the discovery, telomeres and telomerase have been extensively studied, at first, as a mechanism of cellular senescence, and then, as human health and disease indicators. Telomeres that protect chromosomal ends play a vital role in genomic stability by preserving information.…”
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Climate change risks illustrated by the Intergovernmental Panel on Climate Change (IPCC) “burning embers” by P. Marbaix, P. Marbaix, P. Marbaix, A. K. Magnan, A. K. Magnan, A. K. Magnan, V. Muccione, V. Muccione, P. W. Thorne, Z. Zommers

“…<p>The completion of the Sixth Assessment Cycle of the Intergovernmental Panel on Climate Change (IPCC) provides a unique opportunity to understand where the world stands on climate-change-related risks to natural and human systems at the global level, as well as for specific regions and sectors. …”
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Good soil management can reduce dietary zinc deficiency in Zimbabwe by Muneta G. Manzeke-Kangara, Edward J. M. Joy, Florence Mtambanengwe, Prosper Chopera, Michael J. Watts, Martin R. Broadley, Paul Mapfumo

“…Abstract Background Dietary zinc (Zn) deficiency is widespread in sub-Saharan Africa (SSA) with adverse impacts on human health. Agronomic biofortification with Zn fertilizers and improved soil fertility management, using mineral and organic nutrient resources, has previously been shown to increase Zn concentration of staple grain crops, including maize. …”
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Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma by Dirk Hose, Seemun Ray, Sina Rößler, Ulrich Thormann, Reinhard Schnettler, Kim de Veirman, Thaqif El Khassawna, Christian Heiss, Anne Hild, Daniel Zahner, Francisca Alagboso, Anja Henss, Susanne Beck, Martina Emde-Rajaratnam, Jürgen Burhenne, Juliane Bamberger, Eline Menu, Elke de Bruyne, Michael Gelinsky, Marian Kampschulte, Marcus Rohnke, Sabine Wenisch, Karin Vanderkerken, Thomas Hanke, Anja Seckinger, Volker Alt

“…The material’s anti-myeloma activity was assessed using ten human myeloma cell lines (HMCLs) and eight primary myeloma cell samples including four patients refractory to systemic bortezomib treatment. …”
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Economic and relationship-strengthening intervention to reduce alcohol use in couples living with HIV in Malawi: a study protocol for a randomised controlled trial of Mlambe by Torsten B Neilands, Lynae A Darbes, James Mkandawire, Derek S Brown, Fred M Ssewamala, Judith A Hahn, Amy A Conroy, Nancy Mulauzi, Scott Tebbetts

“…Programmatic costs will be ascertained throughout the study and incremental cost-effectiveness ratios will be computed for each arm.Ethics and dissemination The RCT has been approved by the University of California, San Francisco (UCSF) (Human Research Protection Program; Protocol Number 23-40642), and the study has been approved by the National Health Sciences Research Committee (NHSRC; Protocol Number 24/05/4431) in Malawi. …”
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Promotive effect of cancer-testis antigen CT57 on proliferation, invasion, migration and epithelial-mesenchymal transition of liver cancer cells by LUO Lange, ZHENG Chao, LEI Ming

“…Objective·To investigate the effect of cancer-testis antigen family member CT57 on proliferation, migration and invasion of the human liver cancer cells and tumorigenesis in nude mice, and the possible mechanism. …”
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Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation by Meng Zhang, Meng Zhang, Xiaomei Zhang, Xiaomei Zhang, Jiaxi Wang, Wenyi Lu, Xia Xiao, Hairong Lyu, Xiaoyuan He, Yedi Pu, Juanxia Meng, Cuicui Lyu, Xinping Cao, Mingfeng Zhao, Mingfeng Zhao

“…BackgroundHuman C-type lectin-like molecule 1 (CLL-1) represents a promising therapeutic target for Chimeric antigen receptor T (CAR-T) cells therapy in the treatment of acute myeloid leukemia (AML). …”
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Tannin alleviated reproductive dysfunction in pregnant ewes infected with Haemonchus contortus by Xin Li, Xin Li, Hai Xiang, Hai Xiang, Rong Liang, Rong Liang, Xinyu Han, Xinyu Han, Rongzhen Zhong, Rongzhen Zhong, Hongyu Liu, Hongyu Liu, Yi Fang, Yi Fang

“…Finally, fetal weights were measured, and fetal ovarian tissue samples were taken for transcriptomic analysis.ResultsThe results showed that tannins increased the levels of gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), estrogen (E2), progesterone (P4), human chorionic gonadotropin (hCG), red blood cell (RBC) counts, packed cell volume (PCV), and mRNA levels of gonadotropic axis receptors in pregnant ewes infected with H. contortus (p &lt; 0.05). …”
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Primary Clear Cell Adenocarcinoma of the Cervix: A Clinical Analysis of 18 Cases without Exposure to Diethylstilbestrol by Dongying Wang, Chunhua Zhao, Li Fu, Yang Liu, Weiyang Zhang, Tianmin Xu

“…The most common type of lesion was the endocervical type (66.7%, 12/18). The negative rate of human papillomavirus (HPV) examination was 88.9% (8/9). …”
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