Showing 3,261 - 3,280 results of 25,478 for search '"Humanities"', query time: 0.11s Refine Results
  1. 3261

    Soft Lithography and Minimally Human Invasive Technique for Rapid Screening of Oral Biofilm Formation on New Microfabricated Dental Material Surfaces by Marta Alvarez-Escobar, Sidónio C. Freitas, Derek Hansford, Fernando J. Monteiro, Alejandro Pelaez-Vargas

    Published 2018-01-01
    “…Microfabrication offers opportunities to study surface concepts focused to reduce bacterial adhesion on implants using human minimally invasive rapid screening (hMIRS). …”
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  2. 3262
  3. 3263

    To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations by Holli-Joi Sullivan, Xiaoyan Wang, Shaina Nogle, Siyan Liao, Chun Wu

    Published 2020-01-01
    “…Chiglitazar is a promising new-generation insulin sensitizer with low reverse effects for the treatment of type II diabetes mellitus (T2DM) and has shown activity as a nonselective pan-agonist to the human peroxisome proliferator-activated receptors (PPARs) (i.e., full activation of PPARγ and a partial activation of PPARα and PPARβ/δ). …”
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  4. 3264

    TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic Cells by L. Kui, G. C. Chan, P. P. W. Lee

    Published 2017-01-01
    “…Following recombinant human TSG-6 treatment and CpG-A or R837 stimulation, significant reduction in IFN-α and TNF-α was observed in healthy donors’ pDCs, and the same phenomenon was confirmed in GEN2.2. …”
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  5. 3265

    Xylazine as a Drug of Abuse and Its Effects on the Generation of Reactive Species and DNA Damage on Human Umbilical Vein Endothelial Cells by Luz Silva-Torres, Christian Veléz, Lyvia Álvarez, Beatriz Zayas

    Published 2014-01-01
    “…Human xylazine (XYL) abuse among addicts has received great interest due to its potential toxic effects upon addicts and the need to understand the mechanism of action associated with the potential health effects. …”
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  6. 3266
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  8. 3268

    Trace metals potential human health risks assessment through consuming common food spices in Ado Ekiti, Southwest, Nigeria by J.A. Olusola, O.B. Akintan, O. Osanyinlusi

    Published 2025-03-01
    “…While culinary spices are often used for their flavour and colouring capabilities, they also contain significant trace minerals that may be harmful to human health. Objectives: This study aimed to assess the concentrations of trace minerals, including Iron (Fe), Chromium (Cr), Lead (Pb), Cadmium (Cd), and Arsenic (As), in commonly used spices in Ado Ekiti, Nigeria. …”
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  9. 3269

    Efficacy and Safety of Recombinant Human Thrombopoietin (rhTPO) on Coagulation Function and Inflammatory Factors in the Treatment of Patients with Sepsis-Related Thrombocytopenia by Huijuan Wang MD, Dong Chen MD, Ming He MD

    Published 2025-02-01
    “…Background this study aimed to investigate the efficacy of recombinant human thrombopoietin (rhTPO) in the treatment of sepsis-associated thrombocytopenia, and to evaluate its impact on coagulation function, inflammatory markers, platelet (Plt) count, and patient prognosis. …”
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  10. 3270

    Antitumor effects of natural killer cells derived from gene-engineered human-induced pluripotent stem cells on hepatocellular carcinoma by Mayuna Nakamura, Yuka Tanaka, Keishi Hakoda, Masahiro Ohira, Tsuyoshi Kobayashi, Kenji Kurachi, Kouichi Tamura, Hideki Ohdan

    Published 2025-02-01
    “…The eNK cells (HLCN061, developed by HEALIOS K.K.) are human iPSC-derived NK cells differentiated from clinical-grade iPSCs in which IL-15, CCR2B, CCL19, CD16a, and NKG2D have been introduced. …”
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  11. 3271
  12. 3272

    Inhibitory properties of a latent inhibitor after its compound preexposure with several novel stimuli: evidence from human conditioning by Unai Liberal, Gabriel Rodríguez, Paula Nogueiras, James Byron Nelson, Geoffrey Hall, Geoffrey Hall

    Published 2025-02-01
    “…To examine whether this phenomenon generalizes to humans, we conducted two experiments using a video game-based conditioning paradigm. …”
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  13. 3273
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  15. 3275

    Human Settlements Interactions and Deforestation in Gambari Forest Reserve located in Oluyole Local Government Area (LGA) of Oyo State, Nigeria by E.O. Toyinbo, R.A. Fasasi, C.F. Agbor, C.O. Fakorede

    Published 2021-11-01
    “… This study was designed to examine changes in land cover types and the interaction of human settlements with the forest and impact of such interaction on the reserve. …”
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  16. 3276

    Human embryonic stem cells cultured on hydrogels grafted with extracellular matrix protein‐derived peptides with polyethylene glycol joint nanosegments by Abdullah A. Alarfaj, Abdurahman H. Hirad, Murugan A. Munusamy, S. Suresh Kumar, Akon Higuchi

    Published 2022-12-01
    “…Abstract Human pluripotent stem cells (hPSCs) can be proliferated on completely synthetic materials under xeno‐free cultivation conditions using biomaterials grafted with extracellular matrix protein (ECM)‐derived peptides. …”
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  17. 3277

    Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation by Li Chen, Kaikai Shi, Weimin Qiu, Lars Aagaard, Moustapha Kassem

    Published 2020-01-01
    “…Background. Human bone marrow stromal/stem cells (hMSCs, also known as the skeletal stem cells or mesenchymal stem cells) are being employed to study lineage fate determination to osteoblasts, adipocytes, and chondrocytes. …”
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  18. 3278

    Helicobacter pylori Infection Elicits Type I Interferon Response in Human Monocytes via Toll-Like Receptor 8 Signaling by Chalystha Yie Qin Lee, Yee Teng Chan, Yi Ying Cheok, Grace Min Yi Tan, Ting Fang Tang, Heng Choon Cheong, Jamuna Vadivelu, Suhailah Abdullah, Chung Yeng Looi, Won Fen Wong

    Published 2022-01-01
    “…Here, we investigated the involvement of these receptors in the immunity to H. pylori. Human THP-1 monocytic cells were infected with H. pylori, and the expression levels of human Toll-like receptors (TLRs) were examined. …”
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  19. 3279
  20. 3280

    Binding Mode Investigation of Polyphenols from Scrophularia Targeting Human Aldose Reductase Using Molecular Docking and Molecular Dynamics Simulations by Abinaya Manivannan, Prabhakaran Soundararajan, Yoo Gyeong Park, Sugunadevi Sakkiah, Byoung Ryong Jeong

    Published 2015-01-01
    “…In the present study, the binding mode and pharmacokinetic properties of potential polyphenolic compounds with reported aldose reductase inhibitory activity from the genus Scrophularia have been investigated. The human ALR2 enzyme (PDB ID: 2FZD) acted as the receptor in the current study. …”
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