Effect of glucagon-like peptide-1 receptor agonists in osteoarthritis: A systematic review of pre-clinical and human studies by Jacinta Cheng, Tia Solomon, Mahnuma Estee, Flavia M. Cicuttini, Yuan Z. Lim

Subjects: Get full text

Epidemiological Trends of Human Monkeypox Cases in Northern, Southern, Western, and Eastern Regions in Europe: A Cross-Sectional Study by Sultan Ayoub Meo, Abdulaziz Hassan Alsomali, Abdullah Abdulrahman Almushawah, Anusha Sultan Meo

“…This study highlights the prevalence and epidemiological trends of a human monkeypox outbreak in various regions in Europe. …”
Get full text

Incomplete human reference genomes can drive false sex biases and expose patient-identifying information in metagenomic data by Caitlin Guccione, Lucas Patel, Yoshihiko Tomofuji, Daniel McDonald, Antonio Gonzalez, Gregory D. Sepich-Poore, Kyuto Sonehara, Mohsen Zakeri, Yang Chen, Amanda Hazel Dilmore, Neil Damle, Sergio E. Baranzini, George Hightower, Teruaki Nakatsuji, Richard L. Gallo, Ben Langmead, Yukinori Okada, Kit Curtius, Rob Knight

“…We find that insufficient host filtration using prior human genome references can introduce false sex biases and inadvertently permit flow-through of host-specific DNA during bioinformatic analyses, which could be exploited for individual identification. …”
Get full text

Reinforcement and Maintenance of Human Resources for Health Systems during Long-Term Crises: A Systematic Review of Systematic Reviews by Amir Mohammad Salehi, Salman Khazaei, Motahareh Masumi, Farnaz Shavandi, Mostafa Kavand, Ensiyeh Jenabi, Mahnaz Khatiban

“…Background. Human resources are one of the most critical organizational resources, the reinforcement and maintenance of whom require much energy in health organizations, particularly in long-term crises. …”
Get full text

Necrotizing Fasciitis Resulting from Human Bites: A Report of Two Cases of Disease Caused by Group A Streptococci by Christopher A Sikora, Jack Spielman, Kerry MacDonald, Gregory J Tyrrell, John M Embil

Get full text

The Effect of A2E on the Uptake and Release of Calcium in the Lysosomes and Mitochondria of Human RPE Cells Exposed to Blue Light by Mao-Mei Luo, Lin Chen, Shu Wang, Chun Zeng, De-Zhi Li, YeGe Bi, Long-Qian Liu, Shan-Jun Cai

“…Primary human RPE cells were cultured from passages 4 to 6 and exposed to blue light at an intensity of 2000 ± 500 lux for 6 hours. …”
Get full text

Plant Polyphenols and Oxidative Metabolites of the Herbal Alkenylbenzene Methyleugenol Suppress Histone Deacetylase Activity in Human Colon Carcinoma Cells by Isabel Anna Maria Groh, Chen Chen, Claudia Lüske, Alexander Thomas Cartus, Melanie Esselen

“…Evidence has been provided that diet and environmental factors directly influence epigenetic mechanisms associated with cancer development in humans. The inhibition of histone deacetylase (HDAC) activity and the disruption of the HDAC complex have been recognized as a potent strategy for cancer therapy and chemoprevention. …”
Get full text

Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids by Xin-Ru Wen, Jia-Wei Tang, Jie Chen, Hui-Min Chen, Muhammad Usman, Quan Yuan, Yu-Rong Tang, Yu-Dong Zhang, Hui-Jin Chen, Liang Wang

Get full text

Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography by Vineeta Das, Furu Zhang, Andrew J. Bower, Joanne Li, Tao Liu, Nancy Aguilera, Bruno Alvisio, Zhuolin Liu, Daniel X. Hammer, Johnny Tam

“…Abstract Background In vivo imaging of the human retina using adaptive optics optical coherence tomography (AO-OCT) has transformed medical imaging by enabling visualization of 3D retinal structures at cellular-scale resolution, including the retinal pigment epithelial (RPE) cells, which are essential for maintaining visual function. …”
Get full text

The concept of vulnerability and its relation to equality in the context of human rights: cases from climate change, anti-discrimination and asylum by Monika Mayrhofer, Margit Ammer, Katrin Wladasch

Subjects: Get full text

Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts by Sara Baroni, S Romero-Cordoba, I Plantamura, M Dugo, E D’Ippolito, A Cataldo, G Cosentino, V Angeloni, A Rossini, M G Daidone, M V Iorio

“…Here we show that miR-9, upregulated in various breast cancer cell lines and identified as pro-metastatic miRNA, affects the properties of human breast fibroblasts, enhancing the switch to CAF phenotype, thus contributing to tumor growth. …”
Get full text

Retracted: Human Umbilical Mesenchymal Stem Cells-Derived Microvesicles Attenuate Formation of Hypertrophic Scar through Multiple Mechanisms by Stem Cells International

Get full text

In vitro evaluation and comparison of the abrasive capacity of zirconia whitening toothpaste at different concentrations on the radicular dentin surface of human teeth by Miranda Stavileci, Teuta Pustina, Besir Salihu, Jacques Veronneau, Xhevahir Bajrami, Afrim Gjelaj

“…Material and method: This study tested 40 extracted human teeth. After crown removal, root dentin samples were randomly divided into four experimental groups based on zirconia toothpaste concentration: Group A (10 samples) brushed for 5 min with 0.5 % zirconia toothpaste, Group B (10 samples) with 1 %, Group C (10 samples) with 2 %, and the last 10 samples with 5 %.Before brushing, specimens were weighed three times using a precision analytical scale and measured with a Profile Projector. …”
Get full text

Fluctuations in Seminal Quality throughout the Year: How do Temperature, Humidity and Atmospheric Pressure Impact on Human Sperm Quality? by Nicolás David Ramírez, Andrea Tissera, Rosa Molina, Jose Olmedo, Héctor Guillermo Molina, Arnaldo Mangeaud, Ana Carolina Martini

“…Journal of Human Reproductive Sciences…”
Get full text

Evaluating Human Factors in TFM Sizing Accuracy: Statistical Findings from a Round-Robin Programme (Part 2) by Mariana Burrowes M. Guimarães, Edward Ginzel, Gabriela Ribeiro Pereira, Cesar Giron Camerini, Cesar Giron Camerini

“…CIVA simulation software is well known for its ability to reproduce ultrasonic results; however, software simulation cannot fully represent the human factors of uncertainty. To address the human factors, a second part to the programme was organised whereby welds with seeded flaws were provided to volunteers from several labs. …”
Get full text

The Synthesis Followed by Spectral and Calorimetric Evaluation of Stability of Human Milk Fat Substitutes Obtained from Thistle Milk and Lard by Joanna Bryś, lnês Filipa Vaz Flores, Agata Górska, Ewa Ostrowska–Ligęza, Andrzej Bryś, Tomasz Niemiec, Piotr Koczoń

“…The central point of current investigations was the first time ever synthesis of modern substitutes of human milk fat followed by versatile evaluation of their oxidative properties. …”
Get full text

Political ecology survey of human-chimpanzee coexistence within postwar Mabi-Yaya Nature Reserve, Côte d’Ivoire by Sasha Pruvost, Vincent Leblan

“…This situation has made human-chimpanzee coexistence in shared landscapes nearly impossible, except, paradoxically and unsustainably, within protected areas. …”
Get full text

Flavonoids of Rosa rugosa Thunb. inhibit tumor proliferation and metastasis in human hepatocellular carcinoma HepG2 cells by Zhiguo Zhang, Meilin Wang, Shu Xing, Chen Zhang

Subjects: Get full text

Dual RNA sequencing of a co-culture model of Pseudomonas aeruginosa and human 2D upper airway organoids by Cayetano Pleguezuelos-Manzano, Wouter A. G. Beenker, Gijs J. F. van Son, Harry Begthel, Gimano D. Amatngalim, Jeffrey M. Beekman, Hans Clevers, Jeroen den Hertog

Get full text

Critical Studies on Integrating Land-Use Induced Effects on Climate Regulation Services into Impact Assessment for Human Well-Being by Zhihui Li, Xiangzheng Deng, Jikun Huang, Rongrong Zhang, Juan Huang

“…After that, the effects of LUC and climate changes on human well-being via climate regulation services were revisited and commented accordingly. …”
Get full text