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30801
The impact of glucocorticoid receptor transactivation on context-dependent cell migration dynamics
Published 2025-02-01“…Based on data from 1085 human breast cancer specimens, GR pathway expression correlated with migratory, extracellular matrix, and angiogenesis gene signatures. …”
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30802
Photothermal performance of nanofluids: An experimental study on direct absorption solar energy conversion using graphene oxide and its binary composites for water purification
Published 2025-04-01“…Water scarcity affects two-thirds of the world’s population and is one of the most important challenges to human development. Nanotechnology led by solar evaporation is emerging to solve water resource problems by absorbing solar energy to vaporize nanofluid samples, especially in areas where seawater resources are abundant and economical. …”
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30803
Evaluation of the Biochemical and Antioxidant Behaviour of Four Species Chenopodium quinoa Willd, Zea mays L., Triticosecale wittmack and Hordeum vulgare L. Effected by Oxidative S...
Published 2024-12-01“…Cereals and pseudo-cereals, the world's most important crop, are an important source of sustenance for humans and animals. In addition, they are distinguished by their high tolerance to abiotic stressors. …”
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30804
Assessment of Nitrogen Ceilings for Dutch Agricultural Soils to Avoid Adverse Environmental Impacts
Published 2001-01-01“…This leads to a series of environmental impacts, including: (1) nitrate (NO3) contamination of drinking water, (2) eutrophication of freshwater lakes, (3) acidification and biodiversity impacts on terrestrial ecosystems, (4) ozone and particle formation affecting human health, and (5) global climate change induced by emissions of N2O. …”
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30805
Study on Change of Landscape Pattern Characteristics of Comprehensive Land Improvement Based on Optimal Spatial Scale
Published 2025-01-01“…This scale can reflect the spatial variability of the landscape pattern in the study area and is the most suitable analysis range. (3) The fragmentation degree of paddy fields as landscape matrix decreased and the landscape dominance degree increased in the comprehensive land improvement; the degree of fragmentation of irrigated land and agricultural land for facilities increased, the aggregation of land for construction increased, the dominance degree of the pond surface decreased, and the overall landscape diversity of each mosaic decreased; the landscape heterogeneity of ditches, rural roads, forest and grassland corridors was weakened, and the ecosystem service function was weakened. (4) The trend of increased fragmentation, simplification of landscape types, and decreased diversity presented by the landscape pattern clearly indicates that the landscape pattern of the study area has been seriously damaged to some extent under the influence of human activities. This damage not only has a direct negative impact on the local ecological environment, but also poses a potential threat to the sustainable development of the region.…”
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30806
Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study
Published 2025-01-01“…Background: T-shaped uterus is a subclass of dysmorphic uteri according to the European Society of Human Reproductionand Embryology (ESHRE) classification. …”
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30807
Geospatial clustering and correlates of deaths during the Ebola outbreak in Liberia: a Bayesian geoadditive semiparametric analysis of nationally representative cross-sectional sur...
Published 2022-06-01“…The community-level development indicators (global human footprint, gross cell production and population density) had a non-linear associative effect with the observed spatial clustering. …”
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30808
Scalable information extraction from free text electronic health records using large language models
Published 2025-01-01“…Eight advanced open-source LLMs were evaluated against a baseline pattern-matching model. Two human reviewers provided the manual labels, achieving 93% inter-annotator agreement. …”
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30809
Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization
Published 2025-01-01“…So far, the results have been less promising when transitioning to humans and larger animal models due to challenges in oxygenation and insulin delivery. …”
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30810
Management of acute bacterial meningitis in a limited resource setting: an Egyptian consensus model
Published 2025-01-01“…They convened to assess the current situation and develop a new consensus on the management of ABM, taking into consideration the human and health potential of Egypt. All the experts who participated in writing and directing this conference belong to different Egyptian universities, and their main clinical interest was infectious diseases. …”
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30811
Screening of Lactic Acid Bacteria Isolated from Fermented Cowpea and Optimization of Biomass Production Conditions
Published 2025-01-01“…These results demonstrated that the <i>Pediococcus pentosaceus</i> NCU006063 strain has excellent potential as a fermentation agent and can provide a theoretical base for the in-depth exploration and promotion of fermented cowpea use in human diets.…”
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30812
The APOE∗3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis
Published 2019-01-01“…The respective mice respond similarly to lipid-lowering and antidiabetic drugs as humans. The objective of this study was to evaluate/characterize the APOE∗3-Leiden.glucokinase+/− (E3L.GK+/−) mouse as a novel disease model to study the metabolic syndrome and diabetic complications. …”
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30813
The Strength of a Story: Partnering With a Community Organization to Destigmatize Substance Use Disorder
Published 2025-01-01“…Community members expressed how the session helped humanize health care providers and had interest in participating in future sessions. …”
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30814
Measurement the Physiological Properties of Water Pipe Smokers in Shekhan Distract
Published 2019-08-01“…Smoking is one of the old habits used by humans before 400 years ago, where this custom was exclusively used in males with the development of time, tools, ingredients and flavors that used in hookah the women also started smoking, which led to an increase in the prevalence of use in many countries of the world Smoking is one of the reasons that lead to an increase in the percentage incidence of lung cancer, chronic lung disease ,mouth disease ,teeth deformation and gingivitis. …”
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30815
Team Assembly Mechanisms and the Knowledge Produced in the Mexico’s National Institute of Geriatrics: A Network Analysis and Agent-Based Modeling Approach
Published 2019-01-01“…Mexico’s National Institute of Geriatrics (INGER) is the national research center of reference for matters related to human aging. INGER scientists perform basic, clinical, and demographic research which may imply different scientific cultures working together in the same specialized institution. …”
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30816
Hydroxyurea mitigates diabetic kidney disease through mTOR-S6K signaling pathway in STZ-induced diabetic mice
Published 2025-01-01“…This study aims to understand whether the application of HU could be effective to treat DKD.MethodsThe streptozotocin (STZ)-induced diabetic mice, and high glucose (HG)-treated human renal mesangial cells (HRMCs) were used to investigate the effect of HU on DKD. …”
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30817
Modulation of iron metabolism by new chemicals interacting with the iron regulatory system
Published 2025-02-01“…V004-0872 inhibited the human IRP2 via Cys512 and caused decreased iron levels through reciprocal TfR1 downregulation and ferritin upregulation. …”
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30818
Laminin-5 γ2 Chain Expression Correlates with Unfavorable Prognosis in Colon Carcinomas
Published 2001-01-01“…The results indicate that laminin-5 γ2 chain expression is up-regulated during the progression of human colon cancer and that it plays a role in the aggressiveness of these tumors. …”
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30819
Lactylation-driven TNFR2 expression in regulatory T cells promotes the progression of malignant pleural effusion
Published 2024-12-01“…Malignant pleural effusion (MPE) from humans and mouse was used to investigate the potential mechanisms by which lactate regulates TNFR2 expression.Results Treg cells with high TNFR2 expression exhibited elevated levels of immune checkpoint molecules. …”
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30820
International perspective on healthcare provider gender bias in musculoskeletal pain management: a scoping review protocol
Published 2022-06-01“…Additionally, results will be presented in tabular and graphical form.Ethics and dissemination As this study will neither involve human subject participation nor utilisation of protected data, ethical approval is not required. …”
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