In-vitro study of hybrid silver nanoparticles with humic acid extracted from cow dung against pathogens by Shabir Ahmed Dharejo, Tajnees Pirzada, Muhammad Raza Shah, Ahmed Nadeem, Khalid Hussain Thebo

“…The as-prepared AgNPs coupled with humic acid (HA) were characterized by an atomic force microscope (AFM), X-ray powder diffraction (XRD), zeta potential, zeta sizer, Fourier-transform infrared (FT-IR) spectroscopy, and UV–VIS spectrophotometer. Moreover, human plasma, varied salt concentrations, and pH levels were used for stability confirmation using a UV–VIS spectrophotometer. …”
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Key regions aberrantly connected within cerebello-thalamo-cortical circuit and their genetic mechanism in schizophrenia: an fMRI meta-analysis and transcriptome study by Yarui Wei, Ziyu Wang, Kangkang Xue, Xiaoyu Niu, Longyao Ma, Shaoqiang Han, Baohong Wen, Yong Zhang, Huafu Chen, Jingliang Cheng

“…Gene annotation analysis was performed to identify genes over-expressed in these regions by using the Allen Human Brain Atlas, followed by a set of gene functional feature analyses. 19 studies (1333 patients and 1174 healthy controls) were included in this meta-analysis. …”
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Contaminant-degrading bacteria are super carriers of antibiotic resistance genes in municipal landfills: A metagenomics-based study by Fang-Zhou Gao, Wei-Li Jia, Bing Li, Min Zhang, Liang-Ying He, Hong Bai, You-Sheng Liu, Guang-Guo Ying

“…Results showed that the antibiotic resistome in landfills contained 1,403 ARG subtypes, with the total abundance over the levels in natural environments and reaching the levels in human feces and sewage. Therein, 49 subtypes were listed as top priority ARGs for future surveillance based on the criteria of enrichment in landfills, mobilizable and present in pathogens. …”
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Surgical sharp debridement alongside maggot debridement therapy (MDT) for the treatment of diabetic foot ulcers (DFUs): A systematic review of case reports by Babak Choobi Anzali, Anna Javanbakht, Maryam Rasouli, Nasim Talebiazar, Milad Hashemzadeh, Mir Amir Hossein Seyed Nazari

“…Inclusion criteria were studies that reported on the use of surgical sharp debridement alongside MDT for DFUs, while exclusion criteria included insufficient detail on treatment methods or patient outcomes, non-human studies, and non-English publications. Data were extracted using a standardized form, and the quality of case reports was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Case Reports. …”
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Risk Evaluation of Pyrolyzed Biochar from Multiple Wastes by Shem M. Ndirangu, Yanyan Liu, Kai Xu, Shaoxian Song

“…These toxic compounds formed pose a threat to human health through the food chain. Determination of toxicity levels is a first step in the risk management of toxic biochar. …”
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Influence of sacroiliac joint variation on clinical features of axial spondyloarthritis: a comparative analysis by Denis Poddubnyy, Torsten Diekhoff, Sevtap Tugce Ulas, Fabian Proft, Valeria Rios Rodriguez, Judith Rademacher, Juliane Greese, Katharina Ziegeler, Carolina Dominguez Aleixo, Maximilian Lindholz

“…Classification of back pain as inflammatory (=IBP), human leucocyte antigen-B27 positivity, family history, disease activity according to Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), symptom duration, elevated acute phase reactants, peripheral and extramusculoskeletal manifestations were evaluated. …”
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Exposure to lead and cadmium released from ceramics and glassware by Mimoza Rahovica, Arif Latifi, Evgenija Kiroska Petreska, Tatjana Kadifkova Panovska

“…The migration of lead and cadmium from ceramic and glassware used for food contact is a significant source of lead and cadmium intake in humans. This study shed light on the analysis carried out to identify the presence of lead and cadmium in samples of ceramic and glassware, which are available on the market in the Republic of North Macedonia. …”
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Age and Sex‐Related Differences in Neuroprotective Effects of Cardiovascular Endurance on Cortical Thickness and Brain Volume in Adults Across Age by Junyeon Won, Marissa Gogniat, J. Carson Smith

“…Methods This cross‐sectional study included data from 1691 adults across the adult lifespan (22–100 years) from the Human Connectome Project Young Adults and Aging data. 2‐minute walk test performance was used as a proxy of CE. …”
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Construction of complex three-dimensional vascularized liver tissue model in vitro based on a biphasic cell-laden embedding medium by Weikang Lv, Haoran Yu, Abdellah Aazmi, Tuya Naren, Wanli Cheng, Mengfei Yu, Zhen Wang, Xiaobin Xu, Huayong Yang, Liang Ma

“…Constructing an in vitro vascularized liver tissue model that closely simulates the human liver is crucial for promoting cell proliferation, mimicking physiological heterogeneous structures, and recreating the cellular microenvironment. …”
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Synthesis, X-Ray Crystal Structures, Biological Evaluation, and Molecular Docking Studies of a Series of Barbiturate Derivatives by Assem Barakat, Hazem A. Ghabbour, Abdullah Mohammed Al-Majid, Qurat-ul-ain, Rehan Imad, Kulsoom Javaid, Nimra Naveed Shaikh, Sammer Yousuf, M. Iqbal Choudhary, Abdul Wadood

“…All barbiturates derivatives (4a–4x, 4z, and 5a–5m) were found to be noncytotoxic against human prostate (PC-3), Henrietta Lacks cervical (HeLa) and Michigan Cancer Foundation-7 breast (MCF-7) cancer cell lines, and 3T3 normal fibroblast cell line, except 4y which was cytotoxic against all the cell lines.…”
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Mechanism of the blood-brain barrier modulation by cadherin peptides by Elinaz Farokhi, Ahmed L. Alaofi, Vivitri D. Prasasty, Filia Stephanie, Marlyn D. Laksitorini, Krzysztof Kuczera, Teruna J. Siahaan

“…Aim: This study was aimed at finding the binding site on the human E-cadherin for Ala-Asp-Thr Cyclic 5 (ADTC5), ADTC7, and ADTC9 peptides as blood-brain barrier modulator (BBBM) for determining their mechanism of action in modulating the blood-brain barrier (BBB). …”
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How much does government’s short-term response matter for explaining cross-country variation in COVID-19 infection outcomes? A regression-based relative importance analysis of 84 c... by Gordon G Liu, Junjian Yi, Hanmo Yang, Xiaoyun Peng

“…The degree of individualism explains 9.30% of the variation, and the explanatory power of the other socioeconomic factors is less than 4% each.Conclusion The COVID-19 infection outcomes are correlated with multivariate factors, ranging from state NPIs, culture-influenced human behaviours, geographical conditions and socioeconomic conditions. …”
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Antimicrobial activity of Monascus purpureus-derived red pigments against Salmonella typhimurium, Escherichia coli, and Enterococcus faecalis by Islam I. Teiba, Islam Mamdouh, Mokhtar I. Yousef, Ahmed Hussein, Emad H. El-Bilawy

“…Abstract The rise of antimicrobial-resistant microorganisms (AMR) poses a significant global challenge to human health and economic stability. In response, various scientific communities are seeking safe alternatives to antibiotics. …”
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A Spatio-Temporal Deep Learning Model for Automatic Arctic Sea Ice Classification with Sentinel-1 SAR Imagery by Li Zhao, Yufeng Zhou, Wei Zhong, Cheng Jin, Bo Liu, Fangzhao Li

“…Arctic sea ice has a significant effect on global climate change, ship navigation, Arctic ecosystems, and human activities. Therefore, it is essential to produce high-resolution sea ice maps that accurately represent the geographical distribution of various sea ice types. …”
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Research on a traditional Chinese medicine case-based question-answering system integrating large language models and knowledge graphs by Yuchen Duan, Qingqing Zhou, Yu Li, Chi Qin, Ziyang Wang, Hongxing Kan, Hongxing Kan, Jili Hu, Jili Hu

“…The system’s performance, evaluated using the RAGAS framework, achieved high scores: 0.9375 in faithfulness, 0.9686 in answer relevancy, and 0.9500 in context recall; In human evaluations, the levels of safety and usability are significantly higher than those of LLMs without using RAG.DiscussionThe results demonstrate that integrating LLMs with a knowledge graph significantly enhances the efficiency and accuracy of retrieving TCM case information. …”
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High Glucose Induces Endothelial COX2 and iNOS Expression via Inhibition of Monomethyltransferase SETD8 Expression by Jie Qi, Qichao Wu, Qian Cheng, Xiangyuan Chen, Minmin Zhu, Changhong Miao

“…Our previous study indicated that SET domain-containing protein 8 (SETD8) downregulation is involved in high glucose-mediated endothelial inflammation in human umbilical vein endothelial cells (HUVECs). …”
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Citrullinated Autoantigen–Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture by Tim Ammon, Julia Zeiträg, Vanessa Mayr, Manuela Benedicic, Hans‐Peter Holthoff, Martin Ungerer

“…Based on these results, new coculture systems of disease‐relevant cells are developed to simulate human secondary lymphoid tissues ex vivo. This technology will serve as a platform to identify therapies that modulate disease‐specific immune cells.…”
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The Changes in Biochemical Compositions of Five Different Macroalgae and Seagrass (Halophila stipulacea (Forsskal) Ascherson 1867) Collected from Iskenderun Bay by Eyüp İlker Saygılı, Zafer Çetin, Mehmet Naz, Oktay Söyler, Ergün Taşkın, Selin Sayın

“…In conclusion, the information of the biochemical compositions of five different macroalgae and Angiosperms/Seagrass (Halophila stipulacea) are important for the evaluation of potential sources for commercial and human consumption. In addition, biochemical compositions of tested macroalgae and seagrass could make important contributions to feed formulations and functional foods in future.…”
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Groundwater for drinking and sustainable agriculture and public health hazards of nitrate: Developmental and sustainability implications for an arid aquifer system by Boualem Bouselsal, Adel Satouh, Johnbosco C. Egbueri, Mofreh A. Hashim, Ahmed A. Arafat, Prabhu Paramasivam, Ali Alzaed, Enas E. Hussein

“…The integration of the water quality index, health risk assessments, hydrogeochemical modeling, and GIS mapping provides a comprehensive framework for analyzing groundwater in arid regions under pressure from climate change and human activities. These findings highlight the need for integrated strategies for sustainable groundwater management worldwide.…”
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Chitosan nanoparticles loaded with Lactobacillus rhamnosus bioactive metabolites: Preparation, characterization, and antifungal activity by Aya Abdel-Nasser, Hayam M. Fathy, Ahmed N. Badr, Olfat S. Barakat, Amal S. Hathout

“…Aspergillus flavus is a severe danger to worldwide maize (Zea mays) cultivation, due to its extreme toxicity of aflatoxins produced by the fungi, and its ability to cause economic losses while also posing a health concern to humans and animals. Among the measures that may be considered for A. flavus control, applying coatings based on natural ingredients appears to be the most promising. …”
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