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30321
Numerical Analysis on the Storage of Nuclear Waste in Gas-Saturated Deep Coal Seam
Published 2021-01-01“…Nuclear power has contributed humanity a lot since its successful usage in electricity power generation. …”
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30322
Computer-Aided Construction and Evaluation of Poly-L-Lysine/Hyodeoxycholic Acid Nanoparticles for Hemorrhage and Infection Therapy
Published 2024-12-01“…Cytotoxicity and hemolysis tests indicated minimal impact on human cells and significantly reduced hemolysis rates compared to PLL alone. …”
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30323
Pharmacological Evaluation of Secondary Metabolites and Their Simultaneous Determination in the Arabian Medicinal Plant Plicosepalus curviflorus Using HPTLC Validated Method
Published 2019-01-01“…Plicosepalus is an important genus of the Loranthaceae family, and it is a semiparasitic plant grown in Saudi Arabia, traditionally used as a cure for diabetes and cancer in human and for increasing lactation in cattle. A flavonoid quercetin (P1), (-)-catechin (P2), and a flavane gallate 2S,3R-3,3′,4′,5,7-pentahydroxyflavane-5-O-gallate (P3) were isolated from the methanol extract of the aerial parts of P. curviflorus (PCME). …”
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30324
Effects of exercise on vascular remodelling and fetal growth in uncomplicated and abortion-prone mouse pregnancies
Published 2024-12-01“…Abstract Studies in humans and rodents show exercise in pregnancy can modulate maternal blood pressure, vascular volume, and placental efficiency, but whether exercise affects early uteroplacental vascular adaptations is unknown. …”
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30325
Use of linear features by red-legged partridges in an intensive agricultural landscape: implications for landscape management in farmland
Published 2024-02-01“…Through GPS-monitoring of adult birds, we first assess home range size throughout the year and during the breeding season, in relation to breeding status and to linear features (seminatural linear vegetation and tracks-roads for human traffic) density. Then, we focus on habitat selection during the breeding period in relation to linear features. …”
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30326
Early life stress and functional connectivity in antipsychotic-naïve first episode psychosis patients
Published 2025-01-01“…The results also provide support for the long-term differential impact of trauma subtypes on the human brain. Overall, the results contribute to the understanding of the neural mechanisms underlying the association between childhood trauma and psychosis spectrum disorders.…”
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30327
Optimization of Conditions for Expression of Dengue Serotype 2 EDIII Protein in <i>Escherichia coli</i> and Immune Responses of Adjuvant-Free EDIII Ferritin Nanoparticles Against D...
Published 2025-01-01“…Thus, purified DENV2 EDIII and EDIII human ferritin heavy chain nanoparticles were immunized intramuscularly into BALB/c mice without an adjuvant, and the immunogenicity was analyzed using IgG ELISA and a serum-neutralizing assay. …”
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30328
CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions
Published 2025-01-01“…Moreover, we reveal that DUB3 as a bona fide deubiquitinase of YAP1, which functionally links CK2 and YAP1 stability in a variety of human cancers. Mechanistically, CK2α directly phosphorylates DUB3 at Thr495, thereby facilitating DUB3-mediated deubiquitination process of YAP1. …”
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30329
Occurrence of Cytomegalovirus among pregnant antenatal women within Bauchi metropolis, Nigeria
Published 2025-03-01“…Approximately 3 ml of blood was obtained from 300 women using separate 5 ml syringes and Ethylenediamintetraacetic acid (EDTA)-coated bottles. The human ABO blood group and Rhesus factor for each subject were determined using blood group antisera while their plasma screened for CMV IgM by enzyme-linked Imunosorbent assay (ELISA). …”
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30330
Synthesis and Antiviral Evaluation of 5-(4-Aryl-1,3-butadiyn-1-yl)-uridines and Their Phosphoramidate Pronucleotides
Published 2024-12-01“…The antiviral activities of obtained compounds were measured through HTS against RNA viruses including influenza H1N1 and H3N2, human respiratory syncytial virus (RSV), SARS-CoV-2, Zika, hepatitis C virus (HCV), Hepatitis E virus (HEV), as well as against coronavirus (HCoV-229E). …”
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30331
Safe-and-sustainable-by-design redox active molecules for energy storage applications
Published 2025-02-01“…Conclusion Taken together, the modified designs led to safer and more sustainable redox active materials for both humans and the environment at lab scale. Implementing the results mentioned above to further expedite the technology will ultimately pave the way to more sustainable energy storage applications. …”
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30332
The Role of Caspase-4 and NLRP1 in MCF7 Cell Pyroptosis Induced by hUCMSC-Secreted Factors
Published 2020-01-01“…Our previous study showed that the factors secreted by human umbilical cord MSCs (hUCMSCs) induced pyroptosis in the breast cancer cell line MCF7 and our RNA sequencing studies revealed an increase in the expression of the pyroptosis-related gene caspase-4 (CASP4) and nucleotide-binding, leucine-rich repeat pyrin domain-containing protein 1 (NLRP1) in pyroptotic MCF7 cells. …”
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30333
Evaluating the Performance of Low-cost PM Sensors over Multiple COALESCE Network Sites
Published 2023-02-01“…Abstract Air quality is a global concern, with particulate matter receiving considerable attention due to its impact on human health and climate change. Recent advances in low-cost sensors allow their deployment in large number to measure spatio-temporal and real-time air quality data. …”
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30334
Leaflet: Operative Steps for Interventional Studies in Neuroscience
Published 2024-12-01“…Clinical trials are designed to assess the effects of drugs on humans, focusing on determining safety profiles, appropriate modes of administration, and comparative efficacy against placebos. …”
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30335
Tailoring and characterization of bioactive graft material for alveolar bone preservation and regeneration in fresh extraction sockets of dog model
Published 2025-01-01“…Tailored amorphous multiporous bioactive glass (TAMP -BG) was prepared and characterized for bioactivity and response of human alveolar bone marrow mesenchymal stem cells (hABMSCs). …”
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30336
The Effects of Alpha Interferon on the Development of Autoimmune Thyroiditis in the NOD H2h4 Mouse
Published 2003-01-01“…Alternatively, it is possible that αIFN did not induce thyroiditis in mice because, unlike in humans, in mice αIFN does not induce Th1 switching.…”
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30337
Extracellular vesicles-derived miR-21 as a biomarker for early diagnosis and tumor activity in breast cancer subtypes
Published 2025-01-01“…The levels of miR-21 were higher in the MBC group than in the HD group (p = 0.029), mainly in those who were human epidermal growth factor receptor 2 (HER2)+ (p = 0.0005) and hormone receptor-positive (p = 0.036). …”
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30338
An investigator-blinded, 24-month, parallel-group, non-inferiority study to compare aesthetic restorations in primary anterior teeth in a paediatric dental clinic: study protocol f...
Published 2025-02-01“…Secondary outcomes will include tooth survival, longevity of restoration, quality of life, perception and satisfaction of the participants’ parents/guardians.Ethics and dissemination This protocol has been approved by the Human Research Ethics Committee of Universidade Metropolitana de Santos (protocol number: 6.019.297. …”
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30339
Characteristics and Sources of Organic Aerosol Markers in PM2.5
Published 2021-08-01“…These results confirmed that biomass burning can significantly influence the concentrations and chemical compositions of OAs, thereby they can affect human health and atmospheric chemistry.…”
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30340
Alleviating the IL-1β-stimulated extracellular matrix degradation in osteoarthritis, and chondrocyte inflammation by Morinda officinalis polysaccharide via the SIRT6/NF-κB pathway...
Published 2025-01-01“…To investigate, CCK-8 (cell counting kit-8) assays were performed to evaluate MOP’s impact on the viability of human chondrocytes (C28/I2 cells). Cell damage was assessed using flow cytometry and Hoechst 33258 fluorescent staining. …”
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