WIPI-1 Positive Autophagosome-Like Vesicles Entrap Pathogenic Staphylococcus aureus for Lysosomal Degradation by Mario Mauthe, Wenqi Yu, Oleg Krut, Martin Krönke, Friedrich Götz, Horst Robenek, Tassula Proikas-Cezanne

“…By automated fluorescence-based high content analyses, we demonstrate that Staphylococcus aureus strains (USA300, HG001, SA113) stimulate autophagy and become entrapped in intracellular PtdIns(3)P-enriched vesicles that are decorated with human WIPI-1, an essential PtdIns(3)P effector of canonical autophagy and membrane protein of both phagophores and autophagosomes. …”
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Model analysis for an HIV infectious disease using elasticity and sensitivity techniques by Honar J. Hamad, Sarbaz H. A. Khoshnaw, Muhammad Shahzad

“…The human immunodeficiency virus (HIV) is an infection that mainly impacts CD4+ T cells inside the immune system, causing a gradual decline in immunological function. …”
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MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

“…EMT is involved in multiple physiological and pathological processes in the human body. The occurrence of EMT involves many signal transduction pathways and complex molecular mechanisms related to calnexin, growth factors, transcription factors, and the microenvironment. …”
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BTS1-knockout Saccharomyces cerevisiae with broad-spectrum antimicrobial activity through lactic acid accumulation by Liu Cong, Yuan Zhou, Yu Zhang, Shanshan Mao, Chaoqun Chen, Liying Wang, Xiao Li, Zuo Zhang, Zuobin Zhu, Ying Li

“…Bacterial infections pose significant threats to human health, and prudent antibiotic use remains a key strategy for disease treatment and control. …”
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Sustainability assessment of pectin extraction from Citrus paradisi peel to support the encapsulation of lactic acid bacteria by Natalia A. Di Clemente, Enzo La Cava, Sonia Sgroppo, Andrea Gomez-Zavaglia, Esteban Gerbino

“…The main impact categories were climate change, human toxicity with carcinogenic effects and depletion of water resources contributing to deionized water and electricity consumption. …”
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Species classification of Tabanus (Diptera: Tabanidae) in Western Thailand: Integrating DNA barcoding and modern morphometrics by Tanasak Changbunjong, Thekhawet Weluwanarak, Sedthapong Laojun, Tanawat Chaiphongpachara

“…The species of Tabanus, commonly known as horse flies, are remarkable ectoparasites capable of transmitting various pathogens to animals and humans. Given their role in disease transmission, accurate identification of horse fly species is critical but traditionally relies on morphological characteristics, requiring significant expertise and posing a high potential for error, especially with damaged specimens. …”
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Histopathological evaluation of green betel leaf extract ointment on incision wounds infected with Staphylococcus aureus in wistar rats by Winda Irawati Zebua, Linda Chiuman, Edy Fachrial

“…The skin, as the largest organ in both humans and animals, functions as a protective barrier against various external threats such as sharp objects, temperature fluctuations, chemicals, and physical trauma. …”
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Semiautomatic volumetry of the temporal lobes of the brain and correlation with electroencephalography results in dogs with assumed idiopathic epilepsy by Paulina Kinga Drobot, Aleksandra Banasik, Karolina Owsińska‐Schmidt, Marcin Wrzosek, Przemysław Podgórski

“…Automated brain volumetry, widely used in human medicine, can now be applied in veterinary medicine because of the availability of brain atlases. …”
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Communicative strategies and tactics in the speech of Liera Farkash, the heroine of the first season of the TV series Early Swallows by Mariia Bobro, Kateryna Demianiva

“…Communication plays an extremely important role in the life of humans as social beings. The speech of characters in literary works is promising in terms of studying their communicative behavior, since, on the one hand, it reflects the actual speech of a particular period, and on the other, it is to some extent more deliberate, as  the author, in order to realise their creative intention, meticulously thinks over the characters’ words, the linguistic means they use, the style and nature of their communication. …”
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A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth by Marina R. Good, Monica L. Fernández-Quintero, Wei Ji, Alesandra J. Rodriguez, Julianna Han, Andrew B. Ward, Jenna J. Guthmiller

“…We do not observe any binding to α2,6 sialic acids, the receptor used by human seasonal influenza viruses. Using molecular dynamics and a cryo-EM structure of A/Texas/37/2024 H5, we show A/Texas/37/2024 H5 is more flexible within the receptor-binding site compared to a 2.3.4.4b H5 from 2022. …”
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Vaccinating in Different Settings: Best Practices from Italian Regions by Carlo Signorelli, Flavia Pennisi, Anna Carole D’Amelio, Michele Conversano, Sandro Cinquetti, Lorenzo Blandi, Giovanni Rezza

“…Results: In Veneto, where prevention departments were the main actor, herpes zoster vaccination coverage for the 65-year-old cohort increased from 44.4% to 54.9%; in Tuscany, family pediatricians administered 64% of all childhood vaccines; in Liguria, pharmacies delivered 70.1% of COVID-19 vaccines, while vaccinating in schools in Taranto led to higher human papilloma virus vaccination rates compared to regional and national averages. …”
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Hubungan Kepatuhan Minum Obat dan Jumlah CD4 Terhadap Kualitas Hidup Orang dengan HIV AIDS di Poliklinik Voluntary Counseling and Testing RSUP Dr M Djamil Padang by Rihaliza Rihaliza, Arina Widya Murni, Alfitri Alfitri

“…Abstrak Infeksi Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) merupakan salah satu masalah kesehatan masyarakat yang serius yang dapat menimbulkan masalah yang cukup luas yakni meliputi masalah fisik, sosial dan emosional. …”
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Arbuscular mycorrhizal fungi mitigate cadmium stress in maize by Qiqiang Kuang, Yujie Wu, Yamin Gao, Tingting An, Shuo Liu, Liyan Liang, Bingcheng Xu, Suiqi Zhang, Min Yu, Sergey Shabala, Yinglong Chen

“…Soil cadmium (Cd) pollution poses a significant environmental threat, impacting global food security and human health. Recent studies have highlighted the potential of arbuscular mycorrhizal (AM) fungi to protect crops from various heavy metal stresses, including Cd toxicity. …”
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Fine Particulate Matter Deposition in 3D Out-of-Plane Bifurcation Lung Airway by Chun-Chih Chuang, Justus Kavita Mutuku, Chih-Che Chueh, Anurita Selvarajoo, Wei-Hsin Chen

“…While the in-plane airway structures of human lungs are usually used in numerical models, a 3D out-of-plane layout that can geometrically represent triple bifurcations airways of the so-called Weibel model is developed in the present study with the presence of fine particles inside. …”
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Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome by Jonah J. Scott-McKean, Adriano L. Roque, Krystyna Surewicz, Mark W. Johnson, Witold K. Surewicz, Alberto C. S. Costa

“…Because 4xHFS-induced LTP had not yet been characterized in Ts65Dn mice, we also investigated the effects of picrotoxin, amyloid beta oligomers, and soluble recombinant human prion protein (rPrP) on this form of LTP. Whereas ≥10 μM picrotoxin increased LTP to control levels, it also caused seizure-like oscillations. …”
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Ecological drivers shaping mainstem and tributary fish communities in the upper Jinsha River, southeastern Qinghai-Tibet Plateau by Pengcheng Lin, Masami Fujiwara, Baoshan Ma, Zhijun Xia, Xinghua Wu, Chunling Wang, Tao Chang, Xin Gao

“…The upper Jinsha River located in the eastern part of the Qinghai-Tibet Plateau, is experiencing intensified human activities, such as hydropower development. …”
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Complex bacterial diversity of Guaymas Basin hydrothermal sediments revealed by synthetic long-read sequencing (LoopSeq) by John E. Hinkle, John E. Hinkle, Jeffrey P. Chanton, Molly A. Moynihan, Molly A. Moynihan, S. Emil Ruff, S. Emil Ruff, Andreas Teske

“…To improve on these approaches, we use LoopSeq, a high-throughput synthetic long-read sequencing method that has yielded promising results in analyses of microbial ecosystems, such as the human gut microbiome. In this study, LoopSeq is used to obtain near-full length (approximately 1,400–1,500 nucleotides) bacterial 16S rRNA gene sequences from hydrothermal sediments in Guaymas Basin. …”
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Decoding Gestures in Electromyography: Spatiotemporal Graph Neural Networks for Generalizable and Interpretable Classification by Hunmin Lee, Ming Jiang, Jinhui Yang, Zhi Yang, Qi Zhao

“…In recent years, significant strides in deep learning have propelled the advancement of electromyography (EMG)-based upper-limb gesture recognition systems, yielding notable successes across a spectrum of domains, including rehabilitation, orthopedics, robotics, and human-computer interaction. Despite these achievements, prevailing methodologies often overlook the intrinsic physical configurations and interconnectivity of multi-channel sensory inputs, resulting in a failure to adequately capture relational information embedded within the connections of deployed EMG sensor network topology. …”
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Anti-allergic effect of 5,7-dihydroxy-4-methylcoumarin in IgE-mediated RBL-2H3 cells and PCA murine model by Sugeun Gwon, Seong-Ah Shin, Moonsu Kim, Sun Young Moon, Seyeon Choi, Minji Kim, Jun Hyuck Lee, Hyun Ho Park, Chang Sup Lee

“…Therefore, this study was conducted to investigate the anti-allergic effects of 5,7-dihydroxy-4-methylcoumarin in two experimental models: rat basophilic leukemia-2H3 cells sensitized using dinitrophenyl-specific immunoglobulin E (IgE)/human serum albumin and a passive cutaneous anaphylaxis (PCA) murine model. …”
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Physicochemical Characterisation of Water and Sediment of the Semimechanized Artisanal Gold Mining Environment of the Béké Locality by Blanche Mefomdjo Fotie, Harouna Boukari, Ibrahim Elhadji Daou, Christian Kapta Momegni, Manyi Audrey Ebua Eta, Louis Bernard Tchuikoua, Luc Leroy Mambou Ngueyep

“…All these enabled the identification of the potential sources of impacts on the human, physical, and biological environment. Three soil samples (S1, S5, and S7) were collected on the same spot with the water sample and analyzed to assess the intensity of soil contamination. …”
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