Thymus ad astra, or spaceflight-induced thymic involution by Wataru Muramatsu, Wataru Muramatsu, Maria Maryanovich, Maria Maryanovich, Maria Maryanovich, Taishin Akiyama, Taishin Akiyama, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis

“…Understanding these dynamics will not only enhance the safety of human space missions but also provide critical insights into thymus biology under extreme conditions.…”
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YKL-40 as a Novel Factor Associated with Inflammation and Catabolic Mechanisms in Osteoarthritic Joints by Tuija Väänänen, Anna Koskinen, Erja-Leena Paukkeri, Mari Hämäläinen, Teemu Moilanen, Eeva Moilanen, Katriina Vuolteenaho

“…Moreover, IL-6 and IL-17 enhanced YKL-40 production in human primary chondrocyte cultures. The present study introduces YKL-40 as a cartilage-derived factor associated with mediators of inflammation and cartilage destruction involved in the pathogenesis of OA.…”
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The mirror preference test: A reverse translational approach to study anomalous subjective experience in rats by Daria Chestnykh, Liubov S. Kalinichenko, Stephan von Hörsten, Johannes Kornhuber, Christian P. Müller

“…Symptoms related to the misinterpretation of reality are crucial for diagnosis but pose challenges for preclinical research. In humans, a Mirror-Gazing test is used to examine abnormal self-experience and to predict the risk of schizophrenia. …”
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Method of obtaining and storing hyperimmune anthrax serum by S. V. Ivanova, L. A. Melnikova, A. P. Rodionov, V. V. Evstifeev

“…Anthrax is a highly dangerous disease of animals and humans caused by the spore-forming bacterium Bacillus anthracis. …”
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Complementary Non‐invasive Fish Monitoring Distinguishes Depth‐Dependent Fish Communities by Ewan Burns, Vijini Mallawaarachchi, Thomas M. Clarke, Belinda Martin, Joseph D. DiBattista, Jamie Hicks, Danny Brock, Elizabeth A. Dinsdale, Charlie Huveneers, Michael P. Doane

“…ABSTRACT Human activities are increasingly affecting marine environments, with fish communities serving as critical indicators of ecosystem health. …”
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TRANSFORMATION OF THE GENDER DICHOTOMY OF SPIRIT AND BODY IN POSTMODERN PHILOSOPHY AND CULTURE by O. P. Vlasova, Y. V. Makieshyna

“…The changing systems of post paradigm relations, radically transforming human life in the postmodern world, represent the obvious transformations of the fundamental conceptual schemes. …”
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The Prognostic Significance of TRs in Hepatocellular Carcinoma: Insights from TCGA and GEO Databases by Hao Zhou, Weijie Wang, Ruopeng Liang, Rongtao Zhu, Jiahui Cao, Chenguang Sun, Yuling Sun

“…Background: Reduced expression of thyroid hormone receptors (TRs) has been observed in various human malignancies, though its predictive value in hepatocellular carcinoma (HCC) remains uncertain. …”
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Isolation of Helicobacter pylori from Gastric Biopsy of Dyspeptic Patients in Ghana and In Vitro Preliminary Assessment of the Effect of Dissotis rotundifolia Extract on Its Growth by Michael Buenor Adinortey, Charles Ansah, Cynthia Ayefoumi Adinortey, Ansumana Sandy Bockarie, Martin Tangnaa Morna, Damian H. Amewowor

“…Helicobacter pylori (H. pylori) is a gram-negative bacterium that colonizes the human stomach. Infection with this microaerophilic bacterium causes gastric and duodenal ulcer. …”
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Antimicrobial Activity of Aspergillus sp. from the Amazon Biome: Isolation of Kojic Acid by Josy Caldas Rodrigues, Weison Lima da Silva, David Ribeiro da Silva, Carolina Rabelo Maia, Clarice Virginia Santos Goiabeira, Haile Dean Figueiredo Chagas, Gigliola Mayara Ayres D’Elia, Gleica Soyan Barbosa Alves, Viviane Zahner, Cecilia Veronica Nunez, Ormezinda Celeste Cristo Fernandes

“…The elucidated molecule was evaluated for cytotoxicity against the human fibroblast strain (MRC5). The extract presented inhibitory activity against both Gram-positive and negative bacteria, with the range of inhibition halos from 5.3 to 14 mm in diameter and an MIC ranging from 500 to 15.6 μg/mL. …”
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Vision-Based Underwater Docking Guidance and Positioning: Enhancing Detection with YOLO-D by Tian Ni, Can Sima, Wenzhong Zhang, Junlin Wang, Jia Guo, Lindan Zhang

“…This study proposed a vision-based underwater vertical docking guidance and positioning method to address docking control challenges for human-operated vehicles (HOVs) and unmanned underwater vehicles (UUVs) under complex underwater visual conditions. …”
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Evaluation of a compressed air foam system to clean quail rearing facilities by Jill Wright Skrobarczyk, David James Caldwell, Kenneth Scott McKenzie, Ashley Charles Blankenburg, James Allen Byrd, Morgan Brian Farnell

“…This is especially important in cases of salmonellosis where there is a risk of disease transmission to humans. Compressed air foam systems (CAFS) may serve as an alternative carrier for foaming agents to clean and sanitize agricultural surfaces following an outbreak. …”
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Equipping our public health nutrition workforce to promote planetary health: a case example of tertiary education co-designed with students by Ka Po Chau, Wing Chong, Raquel Londono, Beau Cubillo, Julia McCartan, Liza Barbour

“…Students’ descriptions of what planetary health means to them were focused on humans’ role in protecting and preserving the ecosystem, the responsible and sustainable use of natural resources and a need to sustain a healthy life for future generations. …”
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Two-dimensional flood model for risk exposure analysis of land use/land cover in a watershed by G. Puno, R. Puno, I. Maghuyop

“…CONCLUSION: The study highlighted the integration of the findings and recommendations in the localized comprehensive land use plan and implementation to realize the challenge of building a climate change proof and a flood-resilient human settlement in the urbanizing watershed of Solana.…”
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Carboxymethyl Hyaluronan-Stabilized Nanoparticles for Anticancer Drug Delivery by Jessica L. Woodman, Min Sung Suh, Jianxing Zhang, Yuvabharath Kondaveeti, Diane J. Burgess, Bruce A. White, Glenn D. Prestwich, Liisa T. Kuhn

“…These studies tested the ability of CMHA to stabilize the formation of calcium phosphate nanoparticles and evaluated their potential to target therapy resistant, CD44+/CD24−/low human breast cancer cells (BT-474EMT). CMHA stabilized particles (nCaPCMHA) were loaded with the chemotherapy drug cis-diamminedichloroplatinum(II) (CDDP) to form nCaPCMHACDDP. …”
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An electrolyte-gated transistor for the monitoring of a CRISPR/Cas activity by Pierre Guermonprez, Le Tu Anh, Louis Renaud, Pierre Nioche, Eric Krejci, Aurélie Alleaume-Butaux, Nicolas Battaglini, Vu Thi Thu, Sébastien Sanaur, Benoît Piro

“…Detection of Ribonucleic acids (RNA) is a critical step in the identification of viral or bacterial infections in humans and animals. Reverse transcriptase-polymerase chain reaction (RT-PCR) remains the gold standard, but clustered regularly interspaced short palindromic repeats linked to a Cas endoribonuclease particle (CRISPR/Cas) have recently revolutionized the recognition step of two RNAs, i.e. the CRISPR-RNA (crRNA) and the target, providing a much better selectivity compared to the naked hybridization on which RT-PCR is based. …”
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HIV/AIDS prevalence among adolescents in Igbo-Eze South Local Government Area, Enugu State, and the need for faith-based interventions by Favour Chukwuemeka Uroko, Goodness Chimeremma Ike

“…Introduction This study investigated the prevalence of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) among adolescents in Igbo-Eze South Local Government Area (LGA) of Enugu State, Nigeria. …”
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Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang

“…During conducting a first-in-human trial for a new molecular entity, we were able to determine the mechanism of dichotomized variability in plasma drug concentrations, which appeared closely related to adverse drug reactions (ADRs) through integrated omics analysis. …”
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Life Cycle Assessment of Methanol Production from Municipal Solid Waste: Environmental Comparison with Landfilling and Incineration by Cristiano Queiroz Cerqueira, Electo Eduardo Silva Lora, Lidiane La Picirelli de Souza, Márcio Montagnana Vicente Leme, Regina Mambeli Barros, Osvaldo José Venturini

“…To answer this, this study evaluates the environmental performance of MSW-to-methanol technologies using life cycle assessment (LCA), focusing on key indicators such as global warming potential, resource depletion, and impacts on human health and ecosystem quality. The results reveal that methanol production from MSW significantly reduces global warming potential (GWP) by 87% compared to landfilling and 56% compared to incineration. …”
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Infiltration and subtype analysis of CD3 + CD20 + T cells in lung cancer by Liping Luo, Juan Ji, Juan Dong, Maotao He, Wenjun Jiang, Yang Liu, Weidong Wang

“…Abstract Background CD3 + CD20 + T cells (TB cells) are a subset of lymphocytes in the human body that are associated with inflammation. …”
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Factors influencing the adoption of appropriate electronic waste recycling practices in Sub-Saharan Africa: Empirical literature review by Benjamin MWALUGENI, Jacob KIHILA, Alphonce KYESSI

“…This provides a path for the implementation of sustainable development goals that aim to protect human health and the environment. Value: This study revealed that the absence of policies, regulations and recycling infrastructure are some of the factors affecting the adoption of e-waste recycling in sub-Saharan Africa. …”
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