Studi Retrospektif Kanker Kulit di Poliklinik Ilmu Kesehatan Kulit dan Kelamin RS Dr. M. Djamil Padang Periode Tahun 2015-2017 by Silvia Wilvestra, Sri Lestari, Ennesta Asri

“…Faktor peningkatan radiasi sinar ultraviolet, faktor genetik, pola hidup yang tidak sehat, dan infeksi human papillomavirus dapat menjadi pencetus untuk timbulnya kanker kulit. …”
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A Review of Agricultural Film Mapping: Current Status, Challenges, and Future Directions by Mengmeng Zhang, Jinwei Dong, Quansheng Ge, Hasituya, Pengyu Hao

“…The accurate and timely agricultural film maps are expected to support effective land management, rationalize human land use behavior, and inform policy formulation for environmental sustainability.…”
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Anti-HER2 biparatopic antibody KJ015 has near-native structure, functional balanced high affinity, and synergistic efficacy with anti-PD-1 treatment in vivo by Zheng Wang, Yu Liu, Yunxia Xu, Lin Lu, Zhen Zhu, Baojie Lv, Xin Fang, Yao Tang, Jinhua Wang, Yu Cheng, Ying Hu, Junwen Lou, Peican Wu, Chendan Liu, Yanjun Liu, Xin Zeng, Qing Xu

“…Currently approved human epidermal growth factor receptor 2 (HER2)-targeted antibody therapies are largely derived from trastuzumab, including trastuzumab-chemotherapy combinations, fixed-dose trastuzumab-pertuzumab combinations, and trastuzumab antibody-drug conjugates. …”
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Hepatocyte-derived liver progenitor-like cells attenuate liver cirrhosis via induction of apoptosis in hepatic stellate cells by Xu Zhou, Wen-Ming Liu, Han-Yong Sun, Yuan Peng, Ren-Jie Huang, Cai-Yang Chen, Hong-Dan Zhang, Shen-Ao Zhou, Hong-Ping Wu, Dan Tang, Wei-Jian Huang, Han Wu, Qi-Gen Li, Bo Zhai, Qiang Xia, Wei-Feng Yu, He-Xin Yan

“…We have developed a strategy to effectively expand murine and human hepatocyte-derived liver progenitor-like cells (HepLPCs) in vitro. …”
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Antimicrobial Activity and Mode of Action of N-Heterocyclic Carbene Silver(I) Complexes by Giusy Castagliuolo, Michela Di Napoli, Tshering Zangmo, Joanna Szpunar, Luisa Ronga, Anna Zanfardino, Mario Varcamonti, Diego Tesauro

“…Silver drugs have played a vital role in human healthcare for the treatment of infections for many centuries. …”
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LC-MS-Based Global Metabolic Profiles of Alternative Blood Specimens Collected by Microsampling by Marlene N. Thaitumu, Daniel Marques De Sá e Silva, Philippine Louail, Johannes Rainer, Glykeria Avgerinou, Anatoli Petridou, Vassilis Mougios, Georgios Theodoridis, Helen Gika

“…<b>Results:</b> BµS devices, especially Mitra and Capitainer, provided equal or even superior information on the metabolic profiling of human blood based on the number and intensity of features and the precision and stability of some annotated metabolites compared to plasma. …”
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Aluminum-Induced Alterations in Purinergic System Parameters of BV-2 Brain Microglial Cells by Charles Elias Assmann, Vitor Bastianello Mostardeiro, Grazielle Castagna Cezimbra Weis, Karine Paula Reichert, Audrei de Oliveira Alves, Vanessa Valéria Miron, Margarete Dulce Bagatini, Taís Vidal Palma, Cinthia Melazzo de Andrade, Micheli Mainardi Pillat, Fabiano Barbosa Carvalho, Cristina Ruedell Reschke, Ivana Beatrice Mânica da Cruz, Maria Rosa Chitolina Schetinger, Vera Maria Melchiors Morsch

“…Aluminum (Al) is ubiquitously present in the environment and known to be a neurotoxin for humans. The trivalent free Al anion (Al3+) can cross the blood-brain barrier (BBB), accumulate in the brain, and elicit harmful effects to the central nervous system (CNS) cells. …”
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Exploring the operator experience in automated shuttles: Fatigue, attention, and gaze behaviour by Christer Ahlström, My Weidel, Anna Sjörs Dahlman, Ashleigh Filtness, Anna Anund

“…Automated shuttles provide a first look at future transportation, however, they still require on-board human operators for regulatory compliance and safety assurance. …”
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Effect of Chlorhexidine Treatment on Microleakage of Glass Ionomer, Giomer and Methacrylate-Based Composite Restorations in Class V Cavities by Ayşe Aslı Şenol, Seda Özmen, Büşra Karabulut Gençer, Bilge Tarçın, Pınar Yılmaz Atalı

“… Purpose: The aim of this in vitro study was to evaluate the effect of material selection and chlorhexidine digluconate (CHX) pretreatment on microleakage in Class V cavities restored with 3 different restorative materials.Materials and Methods: Thirty freshly extracted sound human molars were cleaned and stored in distilled water. …”
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A multimodal multistream multilevel fusion network for finger joint angle estimation with hybrid sEMG and FMG sensing by Zhouping Chen, Mohamed Amin Gouda, Longcheng Ji, Hong Wang

“…Finger joint angle (FJA) estimation, as a dynamic and fine-grained decoding mode, can support intuitive and natural human–machine interactions. This study is pioneering work dedicated to achieving accurate and clinically friendly FJA estimation. …”
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Revisiting the Metabolism of Donepezil in Rats Using Non-Targeted Metabolomics and Molecular Networking by Eun-Ji Park, Eui-Hyeon Kim, Ki-Young Kim, Ji-Hyeon Jeon, Im-Sook Song, So-Young Park, Kwang-Hyeon Liu

“…<b>Conclusions</b>: The metabolic characteristics of donepezil in rats were comparable to those in humans, indicating that a rat is a reliable model for studying donepezil metabolism. …”
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Users’ experiences of an online intervention for bipolar disorder: important lessons for design and evaluation by Richard Morriss, Steven H Jones, Fiona Lobban, Alyson L Dodd, Sara Mallinson, Martin Griffiths

“…Individual preferences and human contact were key factors for both trial design and engagement with an online intervention.Clinical implications Digital interventions should be co-produced, personalised, interactive and embedded as one component in a broader package of care.Trial registration number ISRCTN56908625; Post-results.…”
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Metallothionein II treatment mitigates rotenone-induced neurodegeneration in zebrafish models of Parkinson’s disease by Yong Hui Nies, Wei Ling Lim, Norwahidah Abd Karim, Mohamad Fairuz Yahaya, Seong Lin Teoh

“…This study explores the neuroprotective potential of exogenous human metallothionein 2 (hMT2) peptide in a rotenone-induced PD zebrafish model.MethodsAdult zebrafish were divided into four groups: control, rotenone-treated, hMT2 pre-treatment, and hMT2 co-treatment. …”
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Analysis of Melanin Concentration on Reflective Pulse Oximetry Using Monte Carlo Simulations by Maximilian Reiser, Oliver Amft, Andreas Breidenassel

“…We conclude that skin tone-adapted calibration should be applied to make reflective pulse oximeter applicable to any human, independent of skin pigmentation.…”
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Estimation of translational importance of mammalian mRNA nucleotide sequence characteristics based on ribosome profiling data by O. A. Volkova, Yu. V. Kondrakhin, R. N. Sharipov

“…A statistical analysis was carried out for revealing relationships between the human and mouse mRNA nucleotide sequence characteristics and ribosome profiling data. …”
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Landscape connectivity alters the evolution of density-dependent dispersal during pushed range expansions by Dahirel, Maxime, Bertin, Aline, Calcagno, Vincent, Duraj, Camille, Fellous, Simon, Groussier, Géraldine, Lombaert, Eric, Mailleret, Ludovic, Marchand, Anaël, Vercken, Elodie

“…As human influence reshapes communities worldwide, many species expand or shift their ranges as a result, with extensive consequences across levels of biological organization. …”
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Pan-caspase inhibitors induce secretion of HIV-1 latency reversal agent lymphotoxin-alpha from cytokine-primed NK cells by Zamaneh Hajikhezri, Ioannis Zygouras, Anders Sönnerborg, Robert van Domselaar

“…Moreover, cytokine-primed but not resting human primary NK cells exhibited LRA activity that could be neutralized with LTα neutralizing antibodies. …”
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A pilot study on the effects of olfactory stimulation with white musk aromatic oil on psychophysiological activity: a crossover study by Fadilla Zennifa, Taisuke Nakashima, Yanli Xu, Saki Koshio, Erika Tomimatsu, Akiko Isa, Katsuya Satake, Fumi Kishida, Kuniyoshi Shimizu

“…Abstract Studies on the compounds of aromatic oils and their effects on psychophysiological changes in humans are often conducted separately. To obtain better validation, a suitable protocol is needed that can be extrapolated to large-scale olfactory stimulation experiments. …”
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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy by Gerhard Frey, Ana Paula G. Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J. Boyle, Jay M. Short

“…Xenograft studies showed that the efficacy of CAB bispecific antibodies is similar to that of a non-CAB anti-EpCAM bispecific antibody, but they have markedly reduced toxicity in non-human primates, indicating an unprecedentedly widened therapeutic index of over 100-fold. …”
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Lactoferrin: a secret weapon in the war against pathogenic bacteria by Lucero Ruiz-Mazón, Gerardo Ramírez-Rico, Mireya de la Garza

“…Because of its effectiveness, accessibility, low cost, and nontoxicity, Lf could be a promising alternative for preventing or treating infections in animals and humans.…”
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