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29121
Exploring Synergies: Greenhouse Gas Dynamics, Soil Mechanisms, and Forest Ecosystems for Climate Resilience and Sustainable Environmental Stewardship
Published 2025-02-01“…This research provides valuable insights for promoting a sustainable balance between human activities and the vital role of forests in maintaining a healthy environment.…”
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29122
Role of the Kaiso gene in the development of inflammation in Mucin-2 defcient mice
Published 2019-01-01“…We have shown that mice with impaired intestinal barrier function that develop processes similar to human IBD also develop inflammatory responses, such as increased expression of Il1, Tnf and Il17a genes. …”
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29123
Phytoconstituent analysis, bioactivity, and safety evaluation of various colors of Chrysanthemum morifolium flower extracts for cosmetic application
Published 2025-02-01“…However, further studies, including human clinical trials, are needed to confirm these biological activities and safety profiles.…”
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29124
The Use of Yoga in the Treatment of PCOS
Published 2025-01-01“…Asana means “comfortable posture,” so any yoga posture is considered optimal for human well-being and balance. There are also more complicated asanas, especially for beginners, that can feel like they are taking away from one’s balance. …”
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29125
HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content
Published 2025-01-01“…Here we show that plasma HDL-FC content varies 2-fold among normolipidemic human subjects and linearly correlates with low-density lipoprotein (LDL)-FC content. …”
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29126
Finger roots (Uvaria chemea) and African greenheart (Cylicodiscus gabunensis): Alternative potent therapy to sildenafil in erectile dysfunction
Published 2025-02-01“…Further investigations are necessary to elucidate the underlying mechanisms of action, determine optimal dosages, and evaluate the long-term safety profiles of these herbal extracts for potential human applications.…”
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29127
Perception, Trust, and Motivation in Consumer Behavior for Organic Food Acquisition: An Exploratory Study
Published 2025-01-01“…(1) Background: A sustainable healthy diet assures human well-being in all life stages, protects environmental resources, and preserves biodiversity. …”
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29128
Artificial intelligence as an asset for the improvement of decision-making cycle in military operations
Published 2024-01-01“…The model shows the possibility of artificial intelligence, together with humans, to be a significant factor in the decision-making process that will ensure supremacy in the process of making decisions. …”
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29129
ALKBH5 acts a tumor-suppressive biomarker and is associated with immunotherapy response in hepatocellular carcinoma
Published 2025-01-01“…The clinical significance of ALKBH5 and TIM3 were evaluated in human HCC tissues. The biological function of ALKBH5 was analyzed in vitro and in vivo. …”
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29130
3-bromo-4-(2-hydroxyethyl)-7-methoxy-2H-chromen-2-one inhibits allergic reactions in IgE-mediated RBL-2H3 cells and a passive cutaneous anaphylaxis mouse model
Published 2025-01-01“…In this study, we investigated the anti-allergic effects of the coumarin derivative 3-bromo-4-(2-hydroxyethyl)-7-methoxy-2H-chromen-2-one in rat basophilic leukemia (RBL)-2H3 cells sensitized to dinitrophenyl (DNP)-immunoglobulin E (IgE) and human serum albumin (HSA). Our results demonstrated that 3-bromo-4-(2-hydroxyethyl)-7-methoxy-2H-chromen-2-one effectively reduces the release of β-hexosaminidase and histamine, inhibiting mast cell degranulation. …”
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29131
Caerin 1.1/1.9-mediated antitumor immunity depends on IFNAR-Stat1 signalling of tumour infiltrating macrophage by autocrine IFNα and is enhanced by CD47 blockade
Published 2025-01-01“…These results indicate that F1/F3 may be effective to improve the efficacy of ICB and therapeutic vaccine-based immunotherapy for human epithelial cancers and warrants consideration for clinical trials.…”
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29132
A Synoptic- and Remote Sensing-based Analysis of a Severe Dust Storm Event over Central Asia
Published 2023-01-01“…The extremely high PM concentrations (PM10 > 10,000 µg m−3 in Tashkent) could endanger both human health and the environment, especially in a region suffering from high susceptibility to wind erosion and significant land degradation and desertification. …”
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29133
Identification of a new alphacoronavirus (Coronaviridae: <i>Alphacoronavirus</i>) associated with the greater horseshoe bat (<i>Rhinolophus ferrumequinum</i>) in the south of Europ...
Published 2024-12-01“…The interspecies transmission of bat coronaviruses to other mammalian hosts, including livestock and humans, can lead to epidemics, epizootics, and global pandemics. …”
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29134
Preventive aspects and patient satisfaction with laser aided gingivectomy versus conventional method. An in-vivo comparative study
Published 2021-07-01“…Gingival diseases are among the most common health problems of human being. Gingivectomy, as a surgical interference can be performed with either scalpel or soft tissue Laser The objective of this study was to evaluate the preventive extent of Diode Laser in regards to gingivectomy associated complications beside the patient`s satisfaction. …”
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29135
Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study
Published 2020-01-01“…In this study, MSCs were isolated from the human umbilical cord (UCMSCs). The ability of UCMSCs to regulate chronic inflammation was investigated in a randomized placebo-controlled pilot study to assess the efficacy and safety of UCMSC therapy in patients with nonhealing wounds. …”
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29136
Removal of ceftriaxone and ciprofloxacin antibiotics from aqueous solutions using graphene oxide derived from corn cob
Published 2024-01-01“…BACKGROUND AND OBJECTIVES: Preliminary studies on the exploration of carbonaceous materials from agricultural waste and their use as adsorbents for antibiotic removal have shown the potential to address a new threat to human health due to antibiotic residue. Therefore, this study developed and synthesized graphene oxide from corn cob for its efficiency in removing ceftriaxone and ciprofloxacin.METHODS: The Hummers methods were used to synthesize graphene oxide from corn cobs. …”
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29137
TRIM25: A Global Player of Cell Death Pathways and Promising Target of Tumor-Sensitizing Therapies
Published 2025-01-01“…Therapy resistance still constitutes a common hurdle in the treatment of many human cancers and is a major reason for treatment failure and patient relapse, concomitantly with a dismal prognosis. …”
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29138
Deep-Sea Ecosystems as an Unexpected Source of Antibiotic Resistance Genes
Published 2024-12-01“…The ratio of nonsynonymous to synonymous substitutions (pN/pS) values of these genes suggest different evolutionary strategies in response to deep-sea conditions and possible human impacts. These resistome profiles provide valuable insights into their natural origins as well as the ecological and evolutionary implications of antibiotic resistance in deep-sea ecosystems. …”
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29139
The Application of CA and PCA to the Evaluation of Lipophilicity and Physicochemical Properties of Tetracyclic Diazaphenothiazine Derivatives
Published 2019-01-01“…Using computer programs, based on different computational algorithms, theoretical values of lipophilicity (AClogP, ALOGP, ALOGPs, miLogP, MLOGP, XLOGP2, and XLOGP3) as well as molecular descriptors (molecular weight, volume of a molecule, dipole moment, polar surface, and energy of HOMO orbitals and LUMO orbitals) and parameters of biological activity: human intestinal absorption (HIA), plasma protein binding (PPB), and blood-brain barrier (BBB), were determined. …”
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29140
Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma
Published 2024-12-01“…Both JPX‐0700/−0750 treatment reduced leukemic cell growth in human AML or NKCL xenograft mouse models significantly, being well tolerated by mice. …”
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