Use of digital data from open sources during the investigation of criminal offenses: certain aspects by Basysta I., Havrylyuk L., Hutnyk A., Khytra A.

“…An analysis of national legislation, national judicial practice, the Berkeley protocol for conducting an investigation using open digital data (hereinafter referred to as the Berkeley Protocol), the practice of the European Court of Human Rights, the International Criminal Court and scientific research, based on which, by means of a synthesis, the basis of the problem was identified. …”
Get full text

Science-based communication and education needed to improve forest carbon science, policy, and management outcomes by Chad C Papa, Kylie Clay, Lauren T Cooper, Scott C Stark

“…Climate change is one of the most pressing issues facing humanity and forests are increasingly seen as a key pathway to mitigating and adapting to the climate crisis. …”
Get full text

Microbiota alterations in patients treated for susceptible or drug-resistant TB by M. Hauptmann, B. Kalsdorf, J.E. Akoh-Arrey, C. Lange, U.E. Schaible

“…BACKGROUND: We investigated alterations of human microbiota under anti-TB therapies in relationship to the level of Mycobacterium tuberculosis drug response. …”
Get full text

Asking the classroom with technology: a systematic literature review by Talha Mahboob Alam, George Adrian Stoica, Özlem Özgöbek

“…This study provides recommendations for technologists (human-centered design, dynamic customization, advanced data protection protocols, cross-platform adaptability), teachers (digital competence, lecture planning, peer collaboration, adaptive teaching), institutions (resources allocation, support of interactive practices, impact monitoring, incentives for teachers) policymakers (training programs, equitable access, funding, and resources, clear guidelines for implementation) for successful implementation.…”
Get full text

Systematic literature review on Calcium Pyrophosphate Deposition (CPPD) nomenclature: condition elements and clinical states— A Gout, Hyperuricaemia and Crystal-Associated Disease... by Georgios Filippou, Antonella Adinolfi, Emilio Filippucci, Nicola Dalbeth, Robert Terkeltaub, Tristan Pascart, Edoardo Cipolletta, Silvia Sirotti, Charlotte Jauffret, Sara Tedeschi, Daniele Cirillo, Luca Ingrao, Alessandro Lucia

“…This systematic literature review constituted its first step and aimed to provide a state-of-the-art analysis of the medical literature of the last 20 years.Methods A systematic literature search was undertaken in the PubMed, Cochrane and Embase databases between 2000 and 2022, restricted to studies on humans and in the English language. Eight reviewers independently and manually extracted labels related to CPPD concepts, according to an a priori list generated by the authors: pathogenic conditions and pathogenic crystal labels, elementary imaging condition elements and asymptomatic and symptomatic condition states. …”
Get full text

The N-acetyltransferase 10 inhibitor [11C]remodelin: synthesis and preliminary positron emission tomography study in mice by Rui Luo, Yiding Zhang, Katsushi Kumata, Lin Xie, Yusuke Kurihara, Masanao Ogawa, Tomomi Kokufuta, Nobuki Nengaki, Feng Wang, Ming-Rong R. Zhang

“…Moreover, remodelin has been found to enhance healthspan in an animal model of the human accelerated ageing syndrome. In this study, we synthesized C-11-labelled remodelin ([11C]remodelin) for the first time as a positron emission tomography (PET) probe and assessed its biodistribution in mice using PET. …”
Get full text

Nucleotide Sequencing and Identification of Some Wild Mushrooms by Sudip Kumar Das, Aninda Mandal, Animesh K. Datta, Sudha Gupta, Rita Paul, Aditi Saha, Sonali Sengupta, Priyanka Kumari Dubey

“…The determined nucleotide sequences of the mushrooms may provide additional information enriching GenBank database aiding to molecular taxonomy and facilitating its domestication and characterization for human benefits.…”
Get full text

Structural basis for the interaction between the Drosophila RTK Sevenless (dROS1) and the GPCR BOSS by Jianan Zhang, Yuko Tsutsui, Hengyi Li, Tongqing Li, Yueyue Wang, Salma Laraki, Sofia Alarcon-Frias, Steven E. Stayrook, Daryl E. Klein

“…Our findings provide a fundamental understanding of the regulatory function of dROS1 and further provide mechanistic insight into the human ortholog and oncogene ROS1.…”
Get full text

Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA) by Wei Zhao, Lisha Lin, Kristen M. Kelly, Lauren A. Opsasnick, Belinda L. Needham, Yongmei Liu, Srijan Sen, Jennifer A. Smith

“…DNA methylation (DNAm) may be a potential mechanism by which stressors get embedded into the human body at the molecular level and subsequently affect health outcomes. …”
Get full text

The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer by M. P. Smal, A. I. Rolevich, T. N. Nabebina, S. A. Krasny, R. I. Goncharova

“…Although the role of RAS gene mutations in the pathogenesis of various human cancers has been established, the clinical significance of these molecular alterations in bladder cancer remains unclear. …”
Get full text

A multiresolution approach with method-informed statistical analysis for quantifying lymphatic pumping dynamics by Mohammad S. Razavi, Katarina J. Ruscic, Elizabeth G. Korn, Marla Marquez, Timothy T. Houle, Dhruv Singhal, Lance L. Munn, Timothy P. Padera

“…For example, the reliability of the peak-and-valley analysis of human lymphatic vessels was increased 3-fold using the described approach. …”
Get full text

Evaluating the Mechanisms of Improved Glucose Homeostasis after Bariatric Surgery in Ossabaw Miniature Swine by Jonathan G. Sham, Vlad V. Simianu, Andrew S. Wright, Skye D. Stewart, Mouhamad Alloosh, Michael Sturek, David E. Cummings, David R. Flum

“…Conclusions. Similar to humans, Ossabaw swine exhibit both obesity-dependent and obesity-independent IR. …”
Get full text

Evaluation of post-earthquake fractures according to anatomical body parts: A retrospective study by Muhammed Furkan Arpaci, Ferhat Tas, Gokce Bagci Uzun, Mehmet Akcicek, Feyza Inceoglu, Mine Argali Deniz, Emre Demirel, Hidir Pekmez

“…Bone fractures that occur in earthquakes threaten human life. The study aims to localize the fractures in earthquake victims according to anatomical regions in the earthquake centered in Kahramanmaraş 2023. …”
Get full text

Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease by Hui Xu, Anakha Ajayan, Ralf Langen, Jeannie Chen

“…We investigated whether these defects extend to the zQ175KI mouse model which is thought to be more representative of the human condition because it was engineered to contain the extended CAG repeat within the endogenous HTT locus. …”
Get full text

Pain in the Prehospital Setting in Rwanda: Results of a Mixed-Methods Quality Improvement Project by A. Rosenberg, E. Uwitonze, M. Dworkin, J. P. D. Guidry, T. Cyuzuzo, D. Banerjee, K. McIntyre, K. Carlyle, J. M. Uwitonze, I. Kabagema, T. Dushime, S. Jayaraman

“…Introduction. Pain is a universal human experience tied to an individual’s health but difficult to understand. …”
Get full text

High-performance UWB Vivaldi antenna on FR4: A cost-effective solution for wearable technologies by Sahar Saleh, Tale Saeidi, Nick Timmons, Bader Alali, Faroq Razzaz, Ayman A. Althuwayb

“…The antenna's suitability for wearable applications was validated through testing on flat and curved human phantoms made of skin, fat, and muscle, showing low Specific Absorption Rate (SAR) values across the UWB spectrum, confirming its safety for body-centric use. …”
Get full text

Characterization and Modelling of Potential Seaborne Disasters, in the ANA Region by Ashraf Labib, Dylan Jones, Natalia Andreassen, Rune Elvegård, Mikel Dominguez Cainzos

“…The Arctic region is inherently dangerous to transportation and human existence due to its extreme climate and environmental conditions, and hence the complexities associated with emergency situations within the maritime domain are amplified when operating within the Arctic and North-Atlantic (ANA). …”
Get full text

A Campus Landscape Visual Evaluation Method Integrating PixScape and UAV Remote Sensing Images by Lili Song, Moyu Wu

“…The results indicate that the tangent method considers the visual impact of the vertical amplitude and the distance between landscape and viewpoints, which is more in line with the real visual perception of the human eyes. In addition, objective quantitative evaluation metrics based on visibility modeling can reflect the visual differences of landscapes from different viewpoints and have good applicability in campus landscape visual evaluation. …”
Get full text

Immune Cell Profiling Reveals a Common Pattern in Premetastatic Niche Formation Across Various Cancer Types by Shigeaki Sugiyama, Kanae Yumimoto, Keiichi I. Nakayama

“…Discussion Validation of our findings in humans will require data on the presence or absence of micrometastases in patients and the accumulation of comprehensive and temporal information on immune cells. …”
Get full text

Ferroptosis triggers mitochondrial fragmentation via Drp1 activation by Lohans Pedrera, Laura Prieto Clemente, Alina Dahlhaus, Sara Lotfipour Nasudivar, Sofya Tishina, Daniel Olmo González, Jenny Stroh, Fatma Isil Yapici, Randhwaj Pratap Singh, Nils Grotehans, Thomas Langer, Ana J. García-Sáez, Silvia von Karstedt

“…Abstract Constitutive mitochondrial dynamics ensure quality control and metabolic fitness of cells, and their dysregulation has been implicated in various human diseases. The large GTPase Dynamin-related protein 1 (Drp1) is intimately involved in mediating constitutive mitochondrial fission and has been implicated in mitochondrial cell death pathways. …”
Get full text