A Roadmap Draft for the Development of Marine Regenerative Medicine in I.R. Iran by Mahdi Mahmoudpour, Iraj Nabipour

“…Educating and training the next generation of human resources to provide a critical national mass of workforce for MRM; 5. …”
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Deep learning-based prediction of HER2 status and trastuzumab treatment efficacy of gastric adenocarcinoma based on morphological features by Zhida Wu, Tao Wang, Junlin Lan, Jianchao Wang, Gang Chen, Tong Tong, Hejun Zhang

“…Abstract Background First-line treatment for advanced gastric adenocarcinoma (GAC) with human epidermal growth factor receptor 2 (HER2) is trastuzumab combined with chemotherapy. …”
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Long-Term Stability and Osteogenic Activity of Recycled Polysulfone-Calcium Silicate Bone Implants In Vitro by Chi-Nan Chang, Yun-Ru Huang, Shinn-Jyh Ding

“…We evaluated the phase, morphology, weight loss, and three-point bending strength of the PSF-based composites after they were soaked in dynamic simulated body fluid (SBF) at pH levels of 7.4 and 5.0 for up to 12 months. Human mesenchymal stem cells (hMSCs) were utilized to assess the osteogenic activity of these composites. …”
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The Role of ChatGPT and AI Chatbots in Optimizing Antibiotic Therapy: A Comprehensive Narrative Review by Ninel Iacobus Antonie, Gina Gheorghe, Vlad Alexandru Ionescu, Loredana-Crista Tiucă, Camelia Cristina Diaconu

“…However, challenges such as inconsistent handling of clinical nuances, susceptibility to unsafe advice, algorithmic biases, data privacy concerns, and limited clinical validation underscore the importance of human oversight and refinement. <b>Conclusions:</b> AI chatbots have the potential to complement antibiotic stewardship efforts by promoting appropriate antibiotic use and improving patient outcomes. …”
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Modeling TB and HIV co-infections by Lih-Ing W. Roeger, Z. Feng, Carlos Castillo-Chávez

“…Tuberculosis (TB) is the leading cause of death among individuals infected with the human immunodeficiency virus (HIV). The study of the joint dynamics of HIV and TB present formidable mathematical challenges due to the fact that the models of transmission are quite distinct. …”
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Mining functional gene modules by multi-view NMF of phenome-genome association by Xu Jin, WenQian He, MingMing Liu, Lin Wang, YaoGong Zhang, YingJie Xu, Ling Ma, YaLou Huang, MaoQiang Xie

“…In the experiments on mining functionally related genes from mouse phenotype ontology and human phenotype ontology, CMNMF effectively improves clustering performance over the baseline methods. …”
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Micro-Characterization of Indoor Deposited Particles Using FTIR, SEM-EDS, and XRD Techniques: A Case Study of a University Campus, Bangladesh by Mamun Mahmud, Kazi ABM Mohiuddin

“…Abstract Micro-characterization of indoor atmospheric particles is essential for understanding atmospheric particle consequences on human health. In this study, the atmospheric particles were collected from inside the different buildings of KUET campus. …”
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Protocol for the development of a global core outcome set for the surgical treatment of differentiated thyroid cancer: a literature review and international Delphi survey by Anton F Engelsman, Romana T Netea-Maier, Christiaan F Mooij, Robin P Peeters, Menno R Vriens, A S Paul van Trotsenburg, Schelto Kruijff, Joep P M Derikx, Faridi S Jamaludin, Daniël J van de Berg, Hanneke M van Santen, Sarah C Clement, Eveline Bruinstroop, Frederik A Verburg, Angelique Seur, Els J M Nieveen van Dijkum

“…The final COS will be reported in accordance with the COS-Standards for Reporting statement.Ethics and dissemination The medical research ethics committee of the Amsterdam UMC confirmed that the Dutch Medical Research Involving Human Subjects Act (WMO) does not apply to this study and that full approval by the committee is not required. …”
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Prognostic significance of mast cell and microvascular densities in malignant peripheral nerve sheath tumor with and without neurofibromatosis type 1 by Roberto André Torres de Vasconcelos, Pedro Guimarães Coscarelli, Thyago Marsicano Vieira, Washington Silva Noguera, Davy Carlos Mendes Rapozo, Marcus André Acioly

“…Recently, the essential role of mast cells in the tumor onset of neurofibromatosis type 1 (NF1)‐associated neurofibromas and MPNSTs was confirmed in both experimental and human studies. In this study, we investigate mast cell density (MCD), microvascular density (MVD), and proliferation index (Ki‐67) in MPNST. …”
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AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1β, and IL-18 by Junhui Zhen, Le Zhang, Jiachao Pan, Shumin Ma, Xiaojian Yu, Xiaobo Li, Shijun Chen, Wenjun Du

“…Following siRNA-mediated knockdown of AIM2 in HBV-infected and HBV-uninfected human glomerular mesangial (HGM) cells, expression of caspase-1, IL-1β, and IL-18 was detected by qRT-PCR and Western blot. …”
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Interleukin-1 Receptor-Associated Kinase 4 Deficiency in a Greek Teenager by Panagiota Karananou, Anastasia Alataki, Efimia Papadopoulou-Alataki

“…Background. Human interleukin- (IL-) 1 receptor-associated kinase 4 (IRAK-4) deficiency is a recently described primary immunodeficiency. …”
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Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis by Alexandra Noble, Rodrigo Motta, Silvia Cabras, Belen Moron Flores, Jan Nowak, Aleksandra Glapa-Nowak, Alessandra Geremia, Jack Satsangi, Emma Culver

“…Epigenetic age acceleration was observed in patients with IgG4-SC, but not in those with PSC or UC. meQTL analyses to identify genetic determinants of methylation revealed a strong human leucocyte antigen (HLA) signal in both PSC and IgG4-SC (HLA-DQB2, HLA-DPA1, HLA-F and HLA-DRA). …”
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Intensification of Natural Disasters in the State of Pará and the Triggering Mechanisms Across the Eastern Amazon by Everaldo B. de Souza, Douglas B. S. Ferreira, Luciano J. S. Anjos, Alan C. Cunha, João Athaydes Silva, Eliane C. Coutinho, Adriano M. L. Sousa, Paulo J. O. P. Souza, Waleria P. Monteiro Correa, Thaiane S. Silva Dias, Alexandre M. C. do Carmo, Carlos B. B. Gutierrez, Giordani R. C. Sodré, Aline M. M. Lima, Edson J. P. Rocha, Bergson C. Moraes, Luciano P. Pezzi, Tercio Ambrizzi

“…The detailed characterization of disasters on a municipal scale is relevant in terms of the scientific contribution applied to the strategic decision-making, planning, and implementation of public policies aimed at early risk management (rather than post-disaster response), which is critical for safeguarding human well-being and strengthening the resilience of Amazonian communities vulnerable to climate change.…”
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EEG-based functional and effective connectivity patterns during emotional episodes using graph theoretical analysis by Majid Roshanaei, Hamzeh Norouzi, Julie Onton, Scott Makeig, Alireza Mohammadi

“…These findings enhance our understanding of emotional processing and have practical applications in mental health, biomarker identification, and human-computer interaction.…”
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Lipidomics-based association study reveals genomic signatures of anti-cancer qualities of pigmented rice sprouts by Rhowell Navarro Tiozon, Rhowell Navarro Tiozon, Erstelle Pasion-Uy, Saleh Alseekh, Saleh Alseekh, Kristel June D. Sartagoda, Shem Gempesaw, Joel H. G. Tolentino, Alisdair R. Fernie, Alisdair R. Fernie, Nese Sreenivasulu

“…This study offers valuable insights into the health-promoting potential of germinated rice sprouts as a rich dietary source of antioxidants beneficial to human health.…”
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Principle and certain nomotechnical characteristics of criminal offences against the constitutional order and security of the Republic of Serbia by Bodrožić Ivana P.

“…Those are two abstract values, the fundamental social importance of which is extremely important for the standard realization of basic human and citizen rights as the most essential object of criminal law protection. …”
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Pollinator species richness and abundance across diverse habitat-types on Terceira Island (Azores, Portugal) by Mário Boieiro, Raúl Oliveira, Ricardo Costa, Paulo Borges

“…The use of a combination of standardised sampling techniques allowed us to collect information on diverse pollinator groups, but, most importantly, the data collected will contribute to assess the impacts of human activities on pollinator abundance and richness and support decision-making on habitat management for pollinators in the Azores.…”
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Safeguarding forest ecosystems: harnessing IoT for fire detection by Iman Atighi, Zhi Zhou

“…Forest fires represent a significant threat to natural ecosystems and human lives, necessitating early detection and rapid response for effective mitigation. …”
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Molecular dynamics simulation of wild and mutant proteasome subunit beta type 8 (PSMB8) protein: Implications for restoration of inflammation in experimental autoimmune encephalomy... by Shamrat Kumar Paul, Md Saddam, Nisat Tabassum, Mahbub Hasan

“…In EAE-MS disease, the level of proteasome subunit beta type-8 (PSMB8), encoded by the PSMB8 gene, is increased and regulates the inflammatory response in this disease. In humans, the Nakajo-Nishimura Syndrome is caused by a mutation in the gene PSMB8, a part of the immunoproteasome subunit. …”
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Microplastics in agricultural soils: sources and microbial remediation approaches by Nataliia Tkachuk, Liubov Zelena, Yaroslav Novikov

“…The sources of microplastics in agricultural soils are plastics used to cover fertilizers, pesticides and seeds, film for mulching, use of wastewater for irrigation, sludge from wastewater treatment as fertilizers that can lead to the occurrence of environmental risks for the functioning of agroecosystems and human health. Microbial remediation is a promising direction for the removal of microplastics from agricultural soils. …”
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