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28781
Physiological Entrainment: A Key Mind–Body Mechanism for Cognitive, Motor and Affective Functioning, and Well-Being
Published 2024-12-01“…Background: The human sensorimotor system can naturally synchronize with environmental rhythms, such as light pulses or sound beats. …”
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28782
Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy
Published 2016-01-01“…Human amniotic-fluid-derived mesenchymal stem cells (AF-MSCs) are interesting for their multilineage differentiation potential and wide range of therapeutic applications due to the ease of culture expansion. …”
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28783
Calculation of Flood Recurrence of Delibekirli Basin (Kırıkhan/Hatay) using Statistical and Deterministic Methods and Modeling with HEC-RAS
Published 2024-07-01“…As an inevitable consequence of population growth, human beings occupying more space on the earth's surface are more likely to encounter and be damaged by natural events. …”
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28784
Long-term correction of hemophilia A via integration of a functionally enhanced FVIII gene into the AAVS1 locus by nickase in patient-derived iPSCs
Published 2025-01-01“…We inserted FE-FVIII with a human elongation factor-1 alpha (EF1α) promoter into the AAVS1 locus of HA patient-derived iPSCs via CRISPR/Cas9 (D10A) nickase to ensure expression in any cell type. …”
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28785
Hypoxia-Inducible Factor-1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae-Induced Pneumosepsis
Published 2021-01-01“…We here determined the role of myeloid cell HIF1α in the host response during pneumonia and sepsis caused by the common human pathogen Klebsiella pneumoniae. To this end, we generated mice deficient for HIF1α in myeloid cells (LysM-cre × Hif1αfl/fl) or neutrophils (Mrp8-cre × Hif1αfl/fl) and infected these with Klebsiella pneumoniae via the airways. …”
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28786
Research on “Identification–Cognition–Perception” of the Pedestrian Spaces Around Subway Stations near Popular Tourist Attractions from the Tourists’ Perspective: A Case Study of T...
Published 2025-01-01“…Future urban spatial optimization research should consider both cognitive and perceptual dimensions, enhancing the comprehensiveness of the human-centered perspective. The research results provide empirical references and guidance for the management and practice of urban space renewal around subway stations near major cities’ tourist attractions.…”
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28787
THE ROLE OF BLACK TEA AND PINEAPPLE JUICE AS NEGATIVE ORAL CONTRASTS ON MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY (MRCP) EXAMINATION
Published 2019-05-01“…Background: Magnetic resonance cholangiopancreatography examination is a superior examination in the detection of anatomic structures or pathological abnormalities in the human pancreatobiliary system. This examination is recommended to use negative oral contrast which aims to eliminate gastrointestinal signals that are around the pancreatobiliary system which can be a barrier to the visualization of the pancreatobiliary tract. …”
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28788
The Cytokine and Bone Protein Expression by Ellagic Acid-Hydroxyapatite in Bone Remodelling Model
Published 2022-01-01“…Ellagic acid, a phenolic compound with anti-inflammatory potential, can be used to accelerate the bone healing process and affect human health, while hydroxyapatite is the most commonly used bone graft material. …”
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28789
Bioinformatics Based Drug Repurposing Approach for Breast and Gynecological Cancers: RECQL4/FAM13C Genes Address Common Hub Genes and Drugs
Published 2025-01-01“…Materials and Methods: Gene intensity values of breast cancer, gynaecological cancers such as cervical, ovarian and endometrial cancers were used from the Gene Expression Omnibus database Affymetrix Human Genome U133 Plus 2.0 Array project. Using the linear modelling method included in the R LIMMA package, genes that differ between healthy individuals and cancer patients were identified. …”
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28790
Are Artificial Sweeteners a Healthier Alternative to Sugar?
Published 2025-02-01“…Aim of the Study This study examines the effects of sweeteners on human health and evaluates their suitability as sugar substitutes for modern consumers, highlighting their benefits and potential risks. …”
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28791
The “best practices for farming” successfully contributed to decrease the antibiotic resistance gene abundances within dairy farms
Published 2025-01-01“…IntroductionFarms are significant hotspots for the dissemination of antibiotic-resistant bacteria and genes (ARGs) into the environment and directly to humans. The prevalence of ARGs on farms underscores the need for effective strategies to reduce their spread. …”
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28792
Modulatory effects of cinnamomi cortex and its components epicatechin and linalool on skin circadian rhythms
Published 2025-02-01“…This study aimed to examine the effects of CC extract and its 18 individual components on the circadian rhythm of HaCaT, an immortalized human keratinocyte line. CC extract and its bioactive components epicatechin (EC) and linalool (LO) significantly enhanced the circadian amplitude without altering the period. …”
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28793
The prognosis for delayed immune recovery in HIV-infected children might be associated with pre-cART CD4+ T cell count irrespective of co-infection with tuberculosis
Published 2025-01-01“…Abstract Background Immune reconstitution following the initiation of combination antiretroviral therapy (cART) significantly impacts the prognosis of individuals infected with human immunodeficiency virus (HIV). Our previous studies have indicated that the baseline CD4+ T cells count and percentage before cART initiation are predictors of immune recovery in TB-negative children infected with HIV, with TB co-infection potentially causing a delay in immune recovery. …”
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28794
Host-microbe computational proteomic landscape in oral cancer revealed key functional and metabolic pathways between Fusobacterium nucleatum and cancer progression
Published 2025-01-01“…Host proteins associated with LPS response, cell migration/adhesion, and metabolism of amino acids were significantly upregulated in the human cancer proteome, whereas the complement cascade was downregulated in malignant samples. …”
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28795
Teenage Pregnancy: Impact of the Integral Attention Given to the Pregnant Teenager and Adolescent Mother as a Protective Factor for Repeat Pregnancy
Published 2007-01-01“…This study was approved by the Human Research Ethics Committee. The Epi-Info v6.0b software was used for data and result evaluation using the means and the chi-squared test. …”
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28796
Targeting SLC4A4: A Novel Approach in Colorectal Cancer Drug Repurposing
Published 2025-01-01“…Methods: The study utilized computational approaches, including receptor-based virtual screening and high-throughput docking, to identify potential SLC4A4 inhibitors. A model of the human SLC4A4 structure was generated based on CryoEM data (PDB ID 6CAA), and drug candidates from the DrugBank database were evaluated using two computational tools (DrugRep and CB-DOCK2). …”
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28797
A girl with intragenic variants in MARS2 and a chondrodysplasia phenotype
Published 2025-03-01“…Background: The human mitochondrial methionyl-tRNA is crucial for mitochondrial translation, serving as both initiator and elongator in polypeptide chains. …”
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28798
“Sichuanvirus”, a novel bacteriophage viral genus, able to lyse carbapenem-resistant Klebsiella pneumoniae
Published 2025-01-01“…Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a severe threat for human health and urgently needs new therapeutic approaches. …”
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28799
Dengue Virus NS1 Protein as a Diagnostic Marker: Commercially Available ELISA and Comparison to qRT-PCR and Serological Diagnostic Assays Currently Used by the State of Florida
Published 2017-01-01“…These comparisons were made among a group of 21 human sera. Results. Nine of 14 (64.3%) DENV qRT-PCR+ samples were also DENV NS1+. …”
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28800
Piezoelectric biomaterials for providing electrical stimulation in bone tissue engineering: Barium titanate
Published 2025-03-01“…Piezoelectric materials have the same piezoelectric effect as human bone, and they are able to deform in response to physiological movement, thus providing electrical stimulation to cells or damaged tissue without the need for an external power source. …”
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