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28181
The Studies of Chlorogenic Acid Antitumor Mechanism by Gene Chip Detection: The Immune Pathway Gene Expression
Published 2013-01-01“…Persistently increasing incident of cancer in human beings has served to emphasize the importance of studies on mechanism of antitumor substances. …”
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28182
Natural antifibrosis potential of anthocyanin in Ipomoea batatas against Transforming Growth Factor beta Type II receptor by in silico ADMET and molecular docking study
Published 2025-01-01“…Purple sweet potato (Ipomoea batatas) are known to have bioactive anthocyanin compounds with numerous human therapeutic benefits. Anthocyanins derived from I. batatas can suppress the action of Transforming Growth Factor beta Type II Receptor (TGFβRII) to prevent fibrosis progression. …”
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28183
Navigating a Climate in Crisis through a Biomimetic Epistemology
Published 2024-12-01“… We have entered a geological epoch where environmental change is driven primarily by human activity. The technology-centric approach to sustainable development as the dominant model of innovation in industrialized countries has led to expansive ecological degradation. …”
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28184
Single-Cell RNA Sequencing Reveals Macrophage Dynamics During MASH in <i>Leptin</i>-Deficient Rats
Published 2025-01-01“…Macrophages play important roles in metabolic dysfunction-associated steatohepatitis (MASH), an advanced and inflammatory stage of metabolic dysfunction-associated steatotic liver disease (MASLD). In humans and mice, the cellular heterogeneity and diverse function of hepatic macrophages in MASH have been investigated by single cell RNA sequencing (scRNA-seq). …”
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28185
Temporal drivers of abundance and community structure of scyphozoan jellyfish in tropical coastal waters
Published 2025-01-01“…Population blooms of scyphozoan jellyfish in tropical shallow water regions can fuel localized fisheries but also negatively impact human welfare. However, there is a lack of baseline ecological data regarding the scyphozoans in the region, which could be used to manage a fast-growing fishery and mitigate potential impacts. …”
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28186
Probiotic Characterization of Lactic Acid Bacteria from Donkey Feces in China
Published 2025-01-01“…Probiotics are beneficial to humans and animals and often used for regulating immunity, intestinal microbiota balance, and animal growth performance. …”
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28187
Inhibition of Horseradish Peroxidase Activity by Boroxine Derivative, Dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH]
Published 2017-01-01“…Recently research shows that horseradish peroxidase, HRP, when combined with other compounds, is highly reactive toward different human tumour cells and that better understanding of catalytic mechanism and inhibition HPR could lead to a new targeted cancer therapy. …”
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28188
The Effect of a Training Program (Retention) on the Clinical Competence, Self-Efficacy, and Occupational Stress of Undergraduate Students of Anesthesia: The Transition from Student...
Published 2024-11-01“… Background: Transferring students from university to the workplace due to facing many challenging and stressful factors is one of the important stages that, if the educational authorities do not pay attention, it leads to low efficiency and an increase in the number of resignations from the workplace, which leads to financial and human losses for the system. Purpose: Investigating the effect of a training program on the clinical competence, self-efficacy, and occupational stress of Anesthesiology undergraduate students, in their transition from the studenthood to the clinical workforce. …”
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28189
Assessment of foot type and comparison of anthropometric foot dimension between foot types of Indian population: A pilot study
Published 2025-01-01“…Background: Human foot morphology is essential for enhancing the fit and comfort of foot-related products in fields like orthopedics, orthotic design, and sports sciences. …”
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28190
From fitness trackers to medical devices: wearable technologies
Published 2023-06-01“…The multiple possibilities they offer have spread towards previously hard-to-imagine fields, like e-health or human physiological monitoring. An application has been developed for its usage in scenarios where data collection is applied to smart spaces, aiming at its usage in firefighting and sports. …”
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28191
Image-guided Control of Transgene Expression Based on Local Hyperthermia
Published 2003-01-01“…A stable modified C6 glioma cell line was used carrying a fused gene coding for thymidine kinase (TK) and green fluorescent protein (GFP) under control of the human heat-shock protein 70 (HSP70) promoter. In vitro studies showed strong induction of the TK-GFP gene expression upon heat shock under various conditions and localization of the protein product in the nucleus. …”
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28192
Multiband Planar Inverted-F Antenna with Independent Operating Bands Control for Mobile Handset Applications
Published 2017-01-01“…The distribution of specific absorption rate for both European and American standards for each operating band and at various distances between the antenna and the human head is also studied.…”
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28193
The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons
Published 2022-01-01“…Motor neurons (MNs) derived from human-induced pluripotent stem cells (hiPSC) hold great potential for the treatment of various motor neurodegenerative diseases as transplantations with a low-risk of rejection are made possible. …”
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28194
3D Face Modeling Algorithm for Film and Television Animation Based on Lightweight Convolutional Neural Network
Published 2021-01-01“…The LW-CNN model adopts a separable convolution structure, which can propose more accurate features with fewer parameters and can extract 3D feature points of a human face. In order to enhance the accuracy of feature extraction, a face detection method based on the inverted triangle structure is used to detect the face frame of the images in the training set before the model extracts the features. …”
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28195
Morphometric Factors Controlling the Old and New Debris-Laden Floods in the South-Southwest Catchment Area of the Esence Mountains with the Example of Günebakan (Erzincan) Flood
Published 2023-07-01“…In this study, the formation and development processes of two flood-overflow events that occurred in Günebakan Stream Basin, the first on 17/07/2011 and the second on 03/07/2020, in the size of a natural disaster and resulted in significant property losses, and their effects on the natural and human environment were examined. In addition, the morphometric characteristics of the Günebakan, Çadırtepe, and Allahmedet stream basins, which are adjacent to each other in the south-southwest catchment area of the Esence Mountains, which surround the Erzincan Plain from the north, were revealed and their flood-overflow potentials were investigated. …”
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28196
A comprehensive environmental index for monitoring ecological quality of typical alpine wetlands in Central Asia
Published 2025-02-01“…Furthermore, the driving factors behind these changes were analyzed by combining meteorological precipitation data with human activities. Long-term monitoring results indicate that the Bayanbulak Wetland has experienced significant expansion, with its ecological quality improving remarkably over the past 45 years, particularly in the Big Urdus basin. …”
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28197
Codon optimized influenza H1 HA sequence but not CTLA-4 targeting of HA antigen to enhance the efficacy of DNA vaccines in an animal model
Published 2024-12-01“…Infections caused by the influenza virus lead to both epidemic and pandemic outbreaks in humans and animals. Owing to their rapid production, safety, and stability, DNA vaccines represent a promising avenue for eliciting immunity and thwarting viral infections. …”
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28198
Targeting the activated allosteric conformation of the endothelin receptor B in melanoma with an antibody-drug conjugate: mechanisms and therapeutic efficacy
Published 2025-01-01“…Methods We previously reported the rendomab B49 antibody (RB49) exhibiting a preferential affinity for the activated conformation of human endothelin B receptor (ETB), not displaced by high endothelin levels, and without any pharmacological properties that could inhibit the division of melanoma cells. …”
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28199
Effect of the Ensemble System Size on the Precipitation Forecast Accuracy
Published 2022-09-01“…The errors in weather forecasting stem from the limitations of human theoretical understanding of the atmosphere and the operational capacity to produce forecasts. …”
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28200
Renal Effects of Hyperbaric Oxygen Therapy in Patients with Diabetes Mellitus: A Retrospective Study
Published 2021-01-01“…Animal experiments suggest HBOT does not harm renal function and may have an antiproteinuric effect, but little is known on the effect of HBOT in humans. We performed a retrospective chart review of 94 patients with diabetes mellitus who underwent HBOT at our institution over an eight-year period. …”
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