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28121
Biogenic silver nanoparticles produced by Trichoderma reesei inhibit SARS-CoV-2 infection, reduce lung viral load and ameliorate acute pulmonary inflammation
Published 2025-01-01“…Additionally, AgNPs impair caspase-1 activation, lactate dehydrogenase release and IL-1β production by human monocytes. Moreover, our study reveals that AgNPs treatment significantly alleviated acute lung injury induced by SARS-CoV-2 infection in Syrian hamsters. …”
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28122
POMA-C: A Framework for Solving the Problem of Precise Anesthesia Control Under Incomplete Observation Environment in Low-Income Areas
Published 2025-01-01“…Through comprehensive ablation experiments—where key observation dimensions are systematically reduced to simulate missing data—POMA-C demonstrates significantly higher decision accuracy and cumulative reward optimization compared to methods like Q-learning and human expertise, even in data-constrained environments. …”
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28123
The TRPV1-PKM2-SREBP1 axis maintains microglial lipid homeostasis in Alzheimer’s disease
Published 2025-01-01“…Lipid-droplet-accumulating microglia were identified in the aging mouse and human brain; however, little is known about the formation and role of lipid droplets in microglial neuroinflammation of Alzheimer’s disease (AD). …”
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28124
Changes in basic composition and in vitro digestive characteristics of pork induced by frozen storage
Published 2025-01-01“…IntroductionFrozen pork can reduce the quality of the meat and alter the digestibility and bioavailability of meat proteins in the human body. In this study, we investigated the changes in the basic composition during frozen storage and their effects on the structural properties of digestion products after protein digestion.MethodsThe impacts of frozen storage at different temperatures (−8, −18, −25, and −40°C) and for different times (1, 3, 6, 9, and 12 months) on the basic components and in vitro digestive characteristics of pork were evaluated.ResultsThe moisture, crude fat, and protein contents decreased with extended storage and increased temperature, whereas muscle juice loss increased (p < 0.05). …”
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28125
Fish scale-inspired biomimetic nanocoatings on magnesium implants for vascularized bone regeneration in infected bone defects
Published 2025-01-01“…Biodegradable magnesium (Mg)-based alloys are desirable for orthopedic implants due to the mechanical properties approximating those of human bone and the released Mg2+ ions essential to osteogenic activity. …”
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28126
P-glycoprotein-independent cytotoxic effects of 5-aminopyrazole in L1210 leukemia cells
Published 2025-04-01“…Five derivatives (A1-A5), each containing perfluorinated methylbenzene at the N3 nitrogen of the pyrazole ring, were tested on murine lymphoblastic cell line variants: parental S cells (P-gp positive), R cells (vincristine-resistant and P-gp positive), and T cells (human P-gp transfected). Among these, A1 and A4 exhibited the strongest effects, especially in R cells, with lesser but similar effects observed in S and T cells. …”
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28127
The influence of depth on the global deep-sea plasmidome
Published 2025-01-01“…Our limited understanding of the deep-sea’s microbial ecology, especially its plasmidome, necessitates caution in human activities like mining. Such activities could have unforeseen impacts on this largely unexplored ecosystem.…”
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28128
Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro
Published 2020-01-01“…Importantly, treatment with human recombinant Asporin protein reduces the mineralization level in osteogenic media-induced aortic valvular interstitial cells with the concomitant decreased level of Wnt/β-catenin signaling. …”
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28129
Anatomical alterations: biparietal thinning in antiquity. Review of published cases and a new case
Published 2025-01-01“…By presenting this new case, we aim to stimulate further research into biparietal thinning and similar cranial pathologies, enriching the broader narrative of human health evolution.…”
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28130
<i>Vibrio cholerae</i> Gut Colonization of Zebrafish Larvae Induces a Dampened Sensorimotor Response
Published 2025-01-01“…Cholera is caused by <i>Vibrio cholerae,</i> which colonizes the upper small intestine in humans once ingested. A growing number of studies suggest that the gut microbiome composition modulates animal behavior. …”
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28131
Predicting Traffic Accident Risk in Seoul Metropolitan City: A Dataset Construction Approach
Published 2025-01-01“…In contemporary society, the rapid progression of urbanization and technological advancements has led to a substantial increase in the number of vehicles, consequently elevating the rate of traffic accidents. To minimize the human and economic losses resulting from these accidents, extensive research has been conducted over the past decades. …”
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28132
Potensi Eugenol Fraksi Etil Asetat Bunga Cengkeh terhadap Proliferasi Kanker Serviks (HeLa Cell Line)
Published 2024-09-01“…<p>Cervix cancer, also known as cervical cancer, is a type of cancer that is caused mainly by oncogenic Human Papillomavirus (HPV), which attacks the cervix. …”
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28133
ELEVATED BLOOD LEAD LEVELS IN WOMEN OF REPRODUCTIVE AGE DUE TO LEADS EXPOSURE FROM CONTAMINATED WATER
Published 2024-03-01“…Background: Water quality can decrease due to population growth, domestic waste handling, climate, and human activities. Most of the people in Cimahi use well water for drinking and eating. …”
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28134
The effect of two commonly consumed energy drinks on the bond strength of conventional and APC® brackets
Published 2019-12-01“…Materials and Methods: Sixty sound human premolars were divided into two groups of conventional and APC® brackets, and each group had three subgroups of control (artificial saliva), Wild Tiger and Red Bull storage. …”
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28135
Study of Abiotic and Biotic Parameters Affecting the Abundance of Mosquito Larvae (Diptera: Culicidae) in the Region of Fez (Morocco)
Published 2020-01-01“…Mosquitoes cause significant human health issues. However, very few studies have attempted to examine the question of how abiotic and biotic factors affect the abundance of Culicidae in the larval habitat. …”
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28136
Prognostic Value of Metastatic Tumoral Caveolin-1 Expression in Patients with Resected Gastric Cancer
Published 2017-01-01“…Caveolin-1 (Cav-1), as the main component of caveolae, has complex roles in tumourigenesis in human malignancies. We investigated Cav-1 in primary and metastatic tumor cells of gastric cancer (GC) and its association with clinical outcomes. …”
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28137
Triglycerides mediate the relationships of per- and poly-fluoroalkyl substance (PFAS) exposure with nonalcoholic fatty liver disease (NAFLD) risk in US participants
Published 2025-01-01“…In conclusion, our study suggested that PFAS mixtures exposure may influence NAFLD risk score by mediating TG in human metabolism. This result could provide more comprehensive epidemiological evidence and guide clinical applications.…”
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28138
Optimizing water resource management in tropical drought-prone regions through hybrid MCDM techniques: A water-stress mapping approach
Published 2025-02-01“…Study focus: Mapping regional water-stress due to climate change and human interventions received less attention in the previous works. …”
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28139
Land use and land cover spatiotemporal dynamic pattern and predicting changes using integrated CA-Markov model
Published 2016-05-01“…Agricultural lands and human-built environment constitute the majority of changes and are increasing continuously. …”
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28140
Parental kidnapping as a form of abuse of parental rights
Published 2024-06-01“…Statistical data from the Secretariat of the Commissioner for Human Rights of the Verkhovna Rada of Ukraine for 2022–2023 regarding the number of parental requests for the unauthorized change of the child’s place of residence by one of the parents is provided. …”
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